• Title/Summary/Keyword: 키트

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Ebola Hemorrhagic Fever Outbreaks: Diagnosis for Effective Epidemic Disease Management and Control (에볼라 출혈열 발병 : 효과적인 전염병 관리 및 통제를 위한 진단)

  • Kang, Boram;Kim, Hyojin;Macoy, Donah Mary;Kim, Min Gab
    • Microbiology and Biotechnology Letters
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    • v.45 no.2
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    • pp.87-92
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    • 2017
  • The first Ebola hemorrhagic fever outbreak occurred in the Democratic Republic of Congo and Sudan in 1976 and then emerged in West Africa in 2014 with a total of 27,741 cases and 11,284 deaths. The fever is caused by the Ebola virus, which belongs to the Filoviridae family and contains a ssRNA genome. The known subtypes of the virus are Bundibugyo ebolavirus, Reston ebolavirus, Sudan ebolavirus, $Ta\ddot{i}$ Forest ebolavirus, and Zaire ebolavirus. The Ebola outbreak was historically originated majorly from the East and Central African tropical belt. The current outbreaks in West Africa caused numerous deaths and spread fear in global society. In the absence of effective treatment strategies and any vaccine, accurate diagnosis is the most important contributing factor in the management and control of the epidemic disease. WHO (World Health Organization) has announced emergency guidance for the selection and use of Ebola in in vitro diagnostic assays. Numerous companies and research institutions have studied the various diagnosis methods and identified four WHO procurement approved as diagnosis kits: RealStar Ebolavirus Screen RT-PCR kit 1.0 (Altona), Liferiver-Ebola Virus (EBOV) Real time RT-PCR kit, Xpert Ebola Assay, and ReEBOV Antigen Rapid Test Kit. The efficiency of novel diagnostic kits such as Rapid Diagnosis Test (RDT) is currently being evaluated.

Reliability Design of the Hinge Kit System in Common Refrigerator Under Repetitive Load (상용 냉장고에서 반복 하중을 받는 힌지 키트 시스템(HKS)의 신뢰성 설계 연구)

  • Woo, Seong-woo;Lee, Jongkil
    • 대한공업교육학회지
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    • v.33 no.2
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    • pp.312-324
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    • 2008
  • To improve the newly designed HKS(hinge kit system) in common refrigerators, it was investigated the new robust methodologies. There were the study of failure modes, mechanisms in the marketplace, and the design parameters of HKS with various improvements using accelerated life testing. Based on the claimed marketplace product returns and 1st ALT reproduction, the fracturing and cracking occur in the housing of the HKS. The missing design parameters of the failed HKS in the design phase of the refrigerator was the housing hinge kit structure. The corrective action plans are the modifications of the housing hinge kit structure from the open supporting to all supporting structure. Based on 2nd ALTs, the fracturing and cracking occur in the torsion shaft. The missing design parameter was the roundness of torsion shaft. After a sequence of ALT testing, the levels of the missing design parameters were setup. The yearly failure rate and B1 life of the redesigned HKS, based on the results of ALT, were over 0.01 percent and 10 years, respectively. The parameter design through the inspection of the failed product, load analysis, and three rounds of ALT, was very effective in the new robust design methodologies of the mechanical system and this method can be applied to other design system.

The Development of Diagnosis for Atopic Dermatitis by Evaluating the Expression of Skin Barrier Proteins Using a Non-Invasive Method (비침습적 피부장벽단백질 측정을 통한 아토피 피부염의 진단 및 유용성)

  • Kim, In Sik;Lee, Ji-Sook
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.4
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    • pp.395-400
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    • 2017
  • Atopic dermatitis is a chronic inflammatory skin disease caused by a variety of genetic and environmental factors, dysregulation of immunological response, as well as dysfunction of the skin barrier proteins. The purpose of this study is to develop an ELISA kit suitable for evaluating the expression of skin barrier proteins. Proteins were obtained from the skin via AriNo and D-Squame patches. The efficiency of protein collection from the skin, using the Arino patch, was shown to be more effective than using D-Squame; while the efficiency of lysis using 0.1% Triton-X100 was higher than that of other lysis solutions, including 0.1 M Tris-HCL, 0.1% Tween-20, and 5 mM KOH. Recombinant skin barrier proteins, such as filaggrin and involucrin, were produced by molecular biological methods. Monoclonal antibodies against filaggrin and involucrin were produced by immunization of mice, fusion of spleen cells and myeloma cells, as well as a selection of antibody-producing hybridoma cells. The filaggrin expression in the skin of subjects suffering from atopic dermatitis was lower than that in normal mice. Involucrin expression was not altered between normal individuals and subjects with atopic dermatitis. These findings contribute to an elucidation of the importance of the skin barrier protein expression in atopic dermatitis and the development of a diagnostic kit for atopic dermatitis.

Fusion Analytical Sensitivity of Rapid Influenza Antigen Limit of Detection Tests for Human Influenza virus (인플루엔자 바이러스에 대한 신속 항원 검출 검사 검출한계의 융합적 분석)

  • Song, Chang-Sub;Sung, Hyun-Ho;Kim, Jung-Hyun;Kim, Dae-Eun;Park, Chang-Eun;Yoon, Joong-Soo
    • Journal of the Korea Convergence Society
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    • v.9 no.3
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    • pp.165-171
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    • 2018
  • In this study, to analyze the detection of limit for sensitivity of the influenza rapid antigen test kit, the positive detection of limits were analyzed by serial dilution of influenza virus A and B type for five influenza rapid antigen test kits in Korea. As a result of analysis, visual measurement of type A were up to 1:8192 for the Wellsbio product and up to 1:4096 for the II product, up to 1:512 for the I and III products, and only 1:128 for the IV product, and type B were positive for up to 1:8192 for the Wellsbio product, up to 1: 4096 for the II product and up to 1:1024 for the I, III and IV products. For instrument readings with the same specimen, both A and B types were found to be positive for up to 1:8192 for the Wellsbio product, up to 1: 4096 for the II product, and up to 1:2048 for the I product. The sensitivity of the rapid antigen test for influenza differs greatly depending on the sampling area of the patient, infection period, specimen volume, etc. Therefore, it is necessary to observe exactly the collection timing and method of the specimen. And it is necessary further study to improve the sensitivity for influenza rapid antigen test.

Evaluation on Odor Removal Performance of Bacteria-Based Odor Reduction Kit for Revetment Blocks (호안블록용 박테리아 기반 악취저감 키트의 악취제거 성능평가)

  • Keun-Hyoek Yang;Ju-Hyun Mun;Ki-Tae Jeong;Hyun-Sub Yoon;Jae-Il Sim
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.12 no.2
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    • pp.229-238
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    • 2024
  • This study evaluated the odor removal performance of a bacteria-based odor reduction kit. The bacteria used were Rhodobacter capsulatus, Paracoccus limosus, and Brevibacterium hankyongi, which can remove ammonia (NH3), hydrogen sulfide (H2S), total nitrogen (T-P), and total phosphorus (T-N), which are odor pollutants. The materials used were bacteria and porous aggregates (expanded vermiculite, zeolite beads, activated carbon), and the combination of the materials varied depending on the removal mechanism. Materials with a physical adsorption mechanism (zeolite beads and activated carbon) gradually slowed down the concentration reduction rate of odor pollutants (NH3, H2S, T-P, and T-N), and had no further effect on reducing the concentration of odor pollutants after 60 hours. Expanded vermiculite, in which bacteria that remove odors through a bio-adsorption mechanism were immobilized, had a continuous decrease in concentration, and the concentration of odor pollutants reached 0 ppm after 108 hours. As a result, the odor removal performance of materials with physical adsorption mechanisms in actual river water did not meet the odor emission standard required by the Ministry of Environment, while the expanded vermiculite immobilized with bacteria satisfied the odor emission permissible standard and achieved water quality grade 1.

소 임신진단키트를 이용한 번식효율 증진

  • 성환후
    • 한우개량
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    • v.6 no.5 s.23
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    • pp.22-27
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    • 2001
  • 한우의 번식에 있어서 번식효율을 증진하기 위해서는 정확한 수정적기의 선택과 수정 후 가능하면 조기에 임신감정을 실시하여 공태기간을 최소로 단축시켜 번식우의 효율을 증진하고 송아지 생산비를 줄여야 할 것이다. 임신감정은 일반적으로 인공수정사나 수의사가 직장검사를 통해 태아를 확인하는 방법이 있으나, 이 방법은 수정 후 50-60일 이후부터 가능하며 숙련자에 따라 진단율이 다르며 암소에게 스트레스를 주고 태아나 난소에 손상을 주거나 심하면 태아의 조기폐사 등의 부작용이 있으며 진단율도 2-3만원 정도 소요된다. 최근 임신진단을 현장에서 간단히 조기에 진단할 수 있는 새로운 방법이 개발되어 있어 소개하기로 한다.

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데이터 글러브를 이용한 자동차 로봇 제어 인터페이스 설계

  • Kwon, Cha-Uk;Kim, Iee-Jo;Cha, Kyung-Ae
    • Proceedings of the Korea Society for Industrial Systems Conference
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    • 2009.05a
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    • pp.93-97
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    • 2009
  • 현재 손가락 및 제스춰 인식 같은 영상처리를 이용하여 로봇의 움직임을 제어하는 방법이 많이 연구되고 있지만, 인식 속도가 느려서 빨리 제어하지 못하는 단점이 있다. 하지만 데이터 글러브와 같은 입력 장치를 이용하면 쉽고 빠르게 제어가 가능하다. 이에 본 논문에서는 로봇 키트를 이용하여 자동차 로봇을 구현하고, 이를 데이터 글러브(Data Glove)와 연동시켜 움직임을 제어하는 방법을 제안한다.

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Integration and Control of A Physical FMS and A Virtual FMS in Web Environment (웹기반에서의 실재 FMS와 가상 FMS의 통합 및 제어)

  • 박정현;구와바라
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
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    • 2001.10a
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    • pp.413-418
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    • 2001
  • 민첩생산의 필요성이 날로 증가하고 있는 생산환경 하에서 대표적인 자동생산시스템인 FMS의 효율적인 운영과 동시에 원격지에서의 FMS 모니터링 및 제어는 필수화되고 있다. 최근에 시뮬레이션을 기반으로 하는 가상생산의 개념이 일반화되고 이를 지원하는 다양한 정보기술의 발전에 따라 FMS에도 적용되고 있다. 본 논문에서는 웹환경 하에서 실재 FMS와 이에 대응되는 가상 FMS를 통합함으로서 원격지에서의 효율적 운영을 지원하는 모니터링 및 제어시스템 구축방법을 소개하고자 한다. 또한 키트형 FMS와 이에 대한 가상 FMS 모델를 대상하여 적용한 결과를 소개하도록 한다.

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8086 프로세서용 인 써키트 에뮬레이터의 제작에 관한 연구

  • 강중용
    • 전기의세계
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    • v.37 no.1
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    • pp.55-62
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    • 1988
  • 본 연구에서는 현재 IBM PC등에 사용되는 8088프로세서의 16비트버젼인 8086프로세서의 ICE를 설계 제작하였다. 8088프로세서와 8086프로세서는 그 내부 기능이 동일하기 때문에 어셈블러나 링커등의 소프트웨어 개발장비들을 IBM PC에서 지원받을 수 있으므로 IBM PC에 연결된 ICE는 전체적으로 하나의 MDS시스템을 구성할 수 있다. 제작된 ICE는 1) 테스트하려는 시스템의 메모리에 대한 읽기 및 쓰기, 2) 테스트프로그램의 실제 조건에서의 수행, 3) 디버깅 기능, 4) ICE의 메모리 영역을 테스트하려는 시스템에서 활용하도록하는 기능 등을 수행할 수 있도록 하였다. 또 8086프로세서는 싱글프로세서모드와 멀티프로세서모드의 두가지 동작 모드가 있는데 싱글프로세서모드에서 동작될 수 있도록 설계되었으며 ICE의 기능 수행을 위한 논리 회로의 구성과 이해에 주안점을 두었다.

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