• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.8 no.1
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• pp.5-11
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• 1997

To set up an objective basis for the evaluation of the stroboscopic findings, video-strobolaryngoscopic images of vocal fold vibration in 5 female and 5 male normal speakers were analyzed using an image analysis computer program called KSIP(Kay Storoboscopy Image Processing, Kay Elemetrics Corp., NJ, USA). Four consecutive vibratory cycles were compared in comfortable, louder, high-pitched /ee/ phonation for every subject. findings mostly replicated earlier studies including glottal chinks which were observed in most female speakers throughout the cycles and clear distinction between female and male speakers in their vibratory patterns as well as intensity and frequency-re-lated differences. However, there were some findings incompatible with those from previous studies which may be attributable to technical problems. This study may provide an objective basis of the stroboscopic findings such as image shape, amplitude, area, and their changes according to frequency and intensity variations. We anticipate that funker study with larger samples ran provide an objective criteria for normal vibratory characteristics of the laryngostro-boscopic findings.

• Proceedings of the KSLP Conference
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• 1994.06a
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• pp.117-127
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• 1994

사람의 성대는 일상회화중 1초에 100∼300번 진동하며 노래를 부를 때에는 100번 이하 또는 1,000번 이상까지 진동하게되므로 우리의 육안으로는 그 자세한 진동상태를 관찰할 수 가 없다. 따라서 이런 경우의 성대 진동상태를 관찰하려면 특수한 검사기기를 사용해야한다. 현재 사용되고 있는 검사법으로는 후두스트로보스코피(laryngostroboscopy), 초고속영화촬영(ultra high speed cinematography), 그로토그라피(glottoraphy) 및 카이모그라피(kymography) 등이 있다. (중략)

• Proceedings of the KSLP Conference
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• 1996.11a
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• pp.92-92
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• 1996

비디오스트로보스코피 화상의 정량화를 통한 glottal cycle의 객관적인 평가는 여러 질환의 감별 및 치료전후의 결과를 비교하는데 중요한 역할을 담당할 수 있으리라 사려되나 아직은 정상 발성시나 병적인 조건에서의 참고치나 그 의미에 대하여 보고된 경우는 흔치 않은 실정이다. 이에 저자들은 정상성인을 대상으로 발성의 주파수와 강도의 변화에 따른 glottal cycle의 변화를 정량화 함으로써 추후 연구나 임상적용 둥의 기본자료로서 활용하고자 하였다. (중략)

• Proceedings of the KOSOMBE Conference
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• v.1989 no.05
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• pp.51-54
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• 1989

In last several years, a number of volume localization techniques, such as ISIS, VSE, SPARS and STEAM etc., have been developed for the MR spectroscopy. These localizing techniques, however, require application of several RF pulses for the 3-D volume selection and suffer from T1 and T2 decays due to relatively long RF excitation time. In this paper, we propose a single-shot RF pulse localization technique to achieve the localized 3-D volume selection. This technique combines the cylindrical volume selection technique with a radial gradient coil with single-shot RF pulse and the oscillating selection gradient technique, so thai it minimizes the volume selection time. We report some experimental results obtained with the proposed method which appears promising for 3-D volume imaging and localized spectroscopy.

• Phonetics and Speech Sciences
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• v.11 no.3
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• pp.69-76
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• 2019

This study aimed to investigate the effects of vocal aerobic treatment (VAT) on the improvement of voice in patients with voice disorders. Twenty patients (13 males, 7 females) were diagnosed with voice disorders on the basis of videostroboscopy and voice evaluations. Acoustic evaluation was performed with the Multidimensional voice program (MDVP) and Voice Range Profile (VRP) of Computerized Speech Lab (CSL), and aerodynamic evaluation with PAS (Phonatory Aerodynamic System). The changes in F0, Jitter, Shimmer, and NHR before and after treatment were measured by MDVP. F0 range and Energy range were measured with VRP before and after treatment, and the changes in Expiratory Volume (FVC), Phonation Time (PHOT), Mean Expiratory Airflow (MEAF), Mean Peak Air Pressure (MPAP), and Aerodynamic Efficiency (AEFF) with PAS. Videostroboscopy was performed to evaluate the regularity, symmetry, mucosal wave, and amplitude changes of both vocal cords before and after treatment. Voice therapy was performed once a week for each patient using the VAT program in a holistic voice therapy approach. The average number of treatments per patient was 6.5. In the MDVP, Jitter, Shimmer, and NHR showed statistically significant decreases (p < .001, p < .01, p < .05). VRP results showed that Hz and semitones in the frequency range improved significantly after treatment (p < .01, p < .05), as did PAS, FVC, and PHOT (p < .01, p < .001). The results for videostroboscopy, functional voice disorder, laryngopharyngeal reflux, and benign vocal fold lesions were normal. Thus, the VAT program was found to be effective in improving the acoustic and aerodynamic aspects of the voice of patients with voice disorders. In future studies, the effect of VAT on the same group of voice disorders should be studied. It is also necessary to investigate subjective voice improvement and objective voice improvement. Furthermore, it is necessary to examine the effects of VAT in professional voice users.

• Proceedings of the KSLP Conference
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• 1997.11a
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• pp.257-257
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• 1997

1996년 10월부터 1997년 6월까지 안ㆍ이비인후과병원과 영동세브란스병원 이비인후과에 음성장애를 주소로 내원한 환자 중 성대양성질환으로 성대미세수술을 시행하고 음성검사를 시행한 환자들을 대상으로 하였다. 대상환자는 총 85명으로 후향적으로 의무기록을 검토하여 수술시 병명, 수술시 레이저(laser)사용유무, 수술 후 발성장애 유무를 확인하였으며 그 중 수술 후 지속적인 혹은 반복적인 발성장애를 보인 환자는 총 12명으로 발성장애의 원인과 치료의 종류 및 치료효과를 판정하기 위해 후두비디오스트로보 스코피 검사, 청각심리검사 및 음성분석을 확인하였으며 통계처리를 하였다. (중략)

• Journal of Yeungnam Medical Science
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• v.25 no.2
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• pp.154-159
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• 2008

Angioleiomyoma of the sinonasal tract is a rare benign tumor. We report a case of angioleiomyoma of the nasal septum in a 51-year-old woman who complained of frequent epistaxis for 3 months. Surgicalexcision was performed. The excised specimen was $0.7{\times}0.5{\times}0.4cm$ in size, well circumscribed, grayish white, rubbery, and soft. Histological examination showed thick-walled blood vessels and smooth muscle cell proliferation. No nuclear atypia or mitoses were present.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.49 no.spc1
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• pp.169-175
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• 2004

동의보감에 수재되어 있는 약쑥은 식용뿐만이 아니고 한방에서는 출혈 및 지혈약으로 자궁출혈, 임신중의 출혈, 코피지혈 등에 효과가 크다고 알려져 왔다. 또한 부인병과 건위, 설사치료와 항암활성, HeLa cell에 대한 억제작용도 보고되어 있다. MeOH엑스가 HCl-EtOH유발법, $1\%$ 암모니아 수용액 유발법, HCl-aspirin 유발법등에 의하여 유발된 위 손상에 대하여 강한 억제 작용을 나타내고 있는데 이는 flavonoid의 일종인 eupatilin으로 확인된 바 있다. 이 물질이 5-lipoxygenase inhibitor ($ID_{50}=14{\times}16^{-6}M$) 작용과 prosta glandin synthase의 활성을 약간 억제한다고 보고되었다. 약쑥의 eupatilin과 jaceosidin을 분리하여 그 화학구조를 구명하였다. 이를 지표물질로 하여 HPLC 분석조건과 HPLC용 검체의 조제, 표준검량선을 작성하였다. 강화사자발쑥 100 g의 잎에는 eupatilin은 240 mg, jaceosidin은 10 mg함유되어 있고 싸주아리쑥에는 eupatilin은 330 mg, jaceosidin은 123 mg 함유되어 있음이 확인되었다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 1998.05a
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• pp.389-393
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• 1998

방사성 핵종의 인위적 방사능 측정과 환경방사능의 측정에 있어서, 발생된 펄스의 에너지와 발생 상대시간을 동시에 측정하여 계수함으로써, 채널분해능과 시간분해능 및 처리속도를 향상시킬 수 있는 ADC 시스템을 개발하였다. 다양한 크기를 갖는 입력펄스의 파고와 관계없이 일정한 불감시간(deadtime)을 갖는 방식으로 시간보정 과정을 필요로 하지 않으며, 측정된 파고와 상대적 불감시간은 동시에 계수되어 방사능 분석을 위한 자료로 제공된다. 본 연구는, 기존에 측정효율을 감소시키는 주요 원인이 되었던 불감시간 보정 과정을 배제하고 전체 스펙트로스 코피(spectroscopy)의 정확도 및 안정도를 유지할 수 있는 변환체계를 개발하며, 특히 측정 환경에 따라 다양하게 적용할 수 있는 불감시간 측정방식을 제공하는 것이다.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.3 no.1
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• pp.22-28
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• 1989

Laryngostroboscopy is one of the most practical techniques for clinical examination of the larynx. The videostroboscopy provides valuable information concerning the nature of vocal folds' vibration, an immediate image of the presence or absence of pathology, and a permanent record. Additionally, when used by trained observers in conjunction with other instrumentation, it can provide both qualitative and quantitative data on vocal function of both the normal and disordered larynx. The authors examined the 388 patients with voice disorders by videostroboscope. This paper describes the clinical procedure of laryngostroboscopy based on some introductory remarks on laryngeal anatomy and function. And the findings of parameters observed by the stroboscopy is noted for the laryngeal disorders.