• Journal of the korean academy of Pediatric Dentistry
• /
• v.35 no.3
• /
• pp.494-503
• /
• 2008

Real-time PCR 기법을 이용하여 구강내 치태에서 특정 세균의 존재여부를 알 수 있을 뿐 아니라 정량적 분석이 가능하게 되었다. 이 연구는 real-time PCR 기법을 이용하여 8-18세의 청소년에서 치주질환 원인균의 조성을 알아보고자 전신질환이 없는 어린이 및 청소년 65명을 대상으로 치은연하의 치태를 채취하여 5종의 치주질환 원인균의 출현율과 그 양을 측정하고, 또한 함께 측정한 치태지수 및 치은지수와의 상관관계를 조사하여 다음과 같은 결론을 얻었다. 1. 치태지수의 평균은 1.33이었으며, 치은지수의 평균은 0.97이었다. 치태지수는 나이가 증가할수록 낮아졌다(p<0.05). 2. 치주질환 원인균의 출현율은 P. gingivalis 61.5%, T. forsythia 53.8%, T. denticola 29.2%, A. actinomycetemcomitans 15.4%, F. nucleatum은 100%였다. P. gingivalis, T. denticola는 10세 이후 출현율이 증가하였고 A. actinomycetemcomitans는 8-10세 군에서 출현율이 높았다(p<0.05). 3. 정량적 분석에서 치태지수와 치은지수는 F. nucleatum의 양과 유의한 상관성이 있었으며, 치태지수는 치은지수와 유의한 상관성이 있었다. T. forsythia는 A. actinomycetemcomitans, T. denticola양과 강한 상관성을 보였으며, T. denticola양과 A. actinomycetemcomitans도 강한 상관관계를 가지고 있었다.

• Journal of Periodontal and Implant Science
• /
• v.35 no.3
• /
• pp.661-674
• /
• 2005

The purpose of this study was to quantify and compare the level of MMP-2, MMP-8 in the healthy, inflammed gingival tissue and inflammed gingival tissue associated with type 2 DM. We investigate whether expression of MMP-2, MMP-8 is increased by chronic periodontitis associated with type 2 DM. Gingival tissue samples were obtained during periodontal surgery or tooth extraction. Based on patient's systemic condition & clinical criteria of gingiva, each gingival samples were divided into three groups. Group l(n=8) is clinically healthy gingiva without bleeding and no evidence of bone resorption or periodontal pockets, obtained from 8 systemically healthy patients. Group 2(n=8) is inflammed gingiva from patients with chronic periodontitis. Group 3(n=8) is inflammed gingiva from type 2 diabetic patients with chronic periodontitis. Tissue samples were prepared and analyzed by Western blotting. The quantification of MMP-2, MMP-8 was performed using a densitometer and statistically analyzed by ANOVA. MMP-2, MMP-8 was expressed in all samples including healthy gingiva and increased in group 3 compared to group 1 and 2, and showed that significant variation was observed between group 1 & 3 in MMP-8 results. In conclusion, this study demonstrated that human gingival tissue with chronic periodontitis associated to type 2 diabetes showed slightly elevated MMP-2, MMP-8 levels compared to healthy gingiva and non-diabetic inflamed gingiva.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2003.10a
• /
• pp.23-23
• /
• 2003

• 건강소식
• /
• v.37 no.2
• /
• pp.28-29
• /
• 2013

치아 및 구강계는 빼놓을 수 없는 신체 재정비기관 중 하나. 소위 풍치로 불리는 치은염, 치주염은 치아를 붙잡아주는 역할을 하는 치주(잇몸)을 약하게 만들어 치아의 배열을 삐뚤어지게 한다.

• 대한치주과학회:학술대회논문집
• /
• 1997.11a
• /
• pp.109-110
• /
• 1997

• 대한치주과학회:학술대회논문집
• /
• 2005.11a
• /
• pp.89-90
• /
• 2005

• 대한치주과학회:학술대회논문집
• /
• 2004.11a
• /
• pp.69-69
• /
• 2004

• 대한치주과학회:학술대회논문집
• /
• 2007.11a
• /
• pp.169-169
• /
• 2007

• Journal of dental hygiene science
• /
• v.10 no.2
• /
• pp.117-122
• /
• 2010

The purpose of this study was to obtain basic data on the relationing between smoking, drinking and periodontal pocket formation. There was no nationwide epidemiologic study on periodontal diseases and smoking, drinking in korea. 177 adults aged 20 and older were recruited the study subjects. Data for smoking, drinking and general characteristics were collected by questions. Periodontal pocket formation was measured greater than 3 mm by probing. Sectional arch numbers of periodontal pocket formation by sex, marriage status and drink yes or no were no statististically difference. Sectional arch numbers of periodontal pocket formation by ages were statististically to increase in proportion to age. Sectional arch numbers of periodontal pocket formation by economic status were statististically to increase in proportion to high economic status. Sectional arch numbers of periodontal pocket formation by smoke yes or no were statististically to increase more smokers than non-smokers. According to regression analysis, periodontal pocket formation was influenced by age, economic status and smoke yes or no.

• Journal of dental hygiene science
• /
• v.12 no.6
• /
• pp.583-590
• /
• 2012

The purpose of this study was to investigate effect of the economic stress and state-trait anxiety on the periodontal disease in order to prevent the occurrence and progression of periodontal disease. Date were collected from total of 326 subjects in their forties and fifties by using questionnaire and examination of periodontal states during the period from February to November 2011. Results were analyzed by using frequency, t-test, ANOVA and Multiple regression of SPSS ver. 19.0. 1. The economic stress were significant statistically to the higher, medium and low of gingival index (p<0.01). 2. The state-trait anxiety were significant statistically to the higher, medium and low of gingival index (p<0.001), of the pocket depth (p<0.05), of the clinical attachment loss (p<0.05). 3. The gingival index were investigate effect of the higher the economic stress ($\beta$=0.052, p<0.01), the higher the state-trait anxiety ($\beta$=0.052, p<0.01). As a result, this study suggests that the dental clinic institute needs to let the patients with the periodontal disease know about the effects of economic stress and state-trait anxiety. They also necessarily need to implement education program including stress management, economic stress, and state-trait anxiety improvement in order to prevent periodontal disease and to take charge.