• Title/Summary/Keyword: 치유인자

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The Effect of Short-term Forest Therapy Camp on Youths with Internet Addiction Risk Group: Focused on the Biological, Neurocognitive and Psychosocial Aspects (인터넷중독 위험 청소년에 대한 단기 산림치유 효과: 생물학적, 신경인지적 및 심리-사회적 측면을 중심으로)

  • Chung, Ahn Soo;Choi, Sam Wook;Woo, Jong Min;Mok, Jung Yeon;Kim, Ki Weon;Park, Bum-Jin
    • Journal of Korean Society of Forest Science
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    • v.104 no.4
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    • pp.657-667
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    • 2015
  • This study examined the effectiveness of 'Forest Therapy (FT)' from the biological, neurocognitive and psychosocial perspectives. Adolescents who were classified as potential internet addicts took part in a FT program for two (once or twice) or three days. Before and after participating the program, Serum Brain-derived neurotrophic factor (BDNF), Comprehensive Attention Test (CAT), Children's Depression Inventory (CDI), and State Anxiety Inventory (STAI) were measured. It was found that FT led to positive consequences, indicated by increased serum BDNF, improved CAT performance, reduced internet use desire, greater resilience, and better social relationship. In addition, FT was partially effective in alleviating state anxiety level, when the participants were classified in accordance with FT exposure lengths. Overall, this study provides evidence that FT reduces symptoms related to internet addiction and promotes various qualities required for well-being.

A Study on Remaining Formaldehyde Concentration in the Synthesis of Self-Healing Microcapsules (자기치유성 마이크로캡슐 합성 공정에서의 포름알데히드 잔류량 연구)

  • Kim, Dong-Min;Lee, Jun-Seo;Ryu, Byung-Cheol;Chung, Chan-Moon
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.8 no.1
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    • pp.129-133
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    • 2020
  • The concentration of remaining formaldehyde contained in waste liquid emitted from the process of urea-formaldehyde microcapsule synthesis was analyzed by gas chromatography-mass spectrometry (GC-MS). Three factors that can affect on the reaction of formaldehyde were selected including pH, ammonium chloride input and temperature. The effect of these factors on the concentration of remaining formaldehyde was studied. When ammonium chloride input was 0.025g, microcapsules could not be obtained or core substance leaked out because of weak shell, and therefore this reaction condition would be inadequate. It was confirmed that the concentration of remaining formaldehyde could be minimized when the microencapsulation was conducted at 70℃ and pH 2.5 by using a ammonium chloride input of 0.050g. This study can make contribution to UF microencapsulation in safer working environment.

A Case of Bacillus licheniformis Bacteremia Associated with Bronchoscopy (기관지 내시경 후에 발생한 Bacillus Licheniformis 균혈증)

  • Hong, Tae Won;Kim, Hyo Youl;Jee, Myeong Gwan;Choi, Joung Wook;Youg, Suk Joong;Shin, Kye Chul;Lee, Won Yeon
    • Tuberculosis and Respiratory Diseases
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    • v.57 no.6
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    • pp.553-556
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    • 2004
  • Bacillus species are aerobic, gram-positive, spore forming rods, and they are usually found in the surrounding environment. If they are isolated in the clinical specimen, they are generally considered as contaminants rather than a true pathogen. Infection with Bacillus licheniformis is usually associated with the immunocompromised state, trauma, an indwelling intravenous catheter or an intravenous drug abuser. This infection is easily controlled by removal of the catheter and surgical debridement of the local infected tissue as well as an appropriate antimicrobial therapy. We reported here on a case of Bacillus licheniformis bacteremia associated with a bronchoscopic procedure in an immune competent patient.

Application Methods of the Natural Topography and Environmental Facts for Building Optimum Eco-Village (최적 생태마을 조성을 위한 자연지형과 환경요인 적용기법 연구)

  • YEON, Sang-Ho
    • Journal of the Korean Association of Geographic Information Studies
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    • v.18 no.4
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    • pp.59-67
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    • 2015
  • There are several methods for building optimal eco-villages in a narrow territory. To derive a new optimal eco-village factors by combining environmental factors from ubiquitous sensor network and topography factors, this study attempted to investigate ecological spaces of specific human settlements, to compare those with the spatial analytical results on natural real settlements, and to draw a construction plan for an optimal ecological village. This study presented a new milestone for building eco-villages in the large or small village units of the entire country in the fact that we can find a living space to make natural healing possible by integrating ecological factors and wellbeing spatial configuration using more healthy natural space. Also, this study proposed a practical method to do so.

Stiffness Analysis of External Fixation System with System Configuration Parameters (시스템 구성 인자를 고려한 외고정장치 시스템의 강성 해석)

  • Kim Yoon Hyuk;Lee Hyun Keun
    • Journal of Biomedical Engineering Research
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    • v.25 no.6
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    • pp.531-536
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    • 2004
  • In fracture treatment with external fixators, the inter-fragmentary movements at the fracture site affect the fracture healing process, and these movements are highly related to the stiffness of external fixation systems. Therefore, in order to provide the optimal fracture healing at the fracture site, it is essential to understand the relationship between the stiffness and the system configurations in external fixation system. In this study we investigated the influences of system configuration parameters on the stiffness in the finite element analysis of an external fixation system of a long bone. The system alignment, the geometric and the material non-linearity of the pin, the joint stiffness and the callus formation were considered in the finite element model. In the first, the system stiffness of the developed finite element model was compared with the experiment data for model validation. The consideration of the joint stiffness and nonlinearity of the model improved the system stiffness results. The joint stiffness, the non-alignment of the system decreased the system stiffness while the callus formation increased the system stiffness. The present results provided the biomechanical basis of rational guidelines for design improvements of external fixators and pre-op. planning to maximize the system stiffness in fracture surgery.

Histological Evaluation on the Biocompatibility and Degradation of Poly Lactic-co Glycolic Acid (PLGA)/Inorganic Filler Matrix in Surgically Created Intrabony 1-wall Defect in Beagle Dog. (비글견 1벽성 골내낭에서 Poly Lactic-co Glycolic Acid (PLGA)/Inorganic Filler Matrix의 생체 친화성 및 흡수성에 대한 조직학적 연구)

  • Lee, Jae-Youn;Kim, Chong-Kwan
    • The Journal of the Korean dental association
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    • v.47 no.6
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    • pp.364-372
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    • 2009
  • 치주 질환으로 인하여 소실된 치주조직을 재생시키려는 여러 술식이 많이 연구되고있다. 그 중 bioactive factor의 적용은 치주조직의 재생에 있어서 우수한 치료법으로 평가되고 있으며, 이를 수용부에 적절히 적용하기 위한 운반체로 생체친화적인 중합체가 이용되고 있다. 본 연구의 목적은 PLGA를 Inorganic filler에 혼합시킨 재료를 성견의 일벽성 골내낭에 적용하여 이 재료의 생체 친화성과 생체 흡수도를 보고자 하는 것이다. 5마리의 비글견에서 제 3 소구치를 모두 발치한 뒤, 8주간의 치유기간이 지나고 제 2 소구치 원심면과 제 4 소구치 근심면에 5mm 깊이, 4mm폭의 일벽성 골내낭을 형성하였다. 좌측 defect에는 PLGA/inorganic filler matrix를 이식하였고 우측에는 아무것도 이식하지 않은 대조군으로 나누어 술 후 8주에 희생하여 치유 결과를 조직학적으로 비교 관찰하였다. 조직학적 분석 결과, 모든 결손부에서 염증의 소견이 관찰되지 않았으며 치근흡수와 유착은 발견되지 않았다. 백악질과 치조골, 치주인대를 포함한 치주조직의 재생에 있어서 대조군, 실험군 간에 조직학적으로 치유양상에 있어 차이를 많이 보이지 않았으며 PLGA/inorganic filler matrix는 8주 내에 완전히 흡수되어 결합조직이나 신생골내에서 그 흔적을 발견할 수 없었다. 이러한 결과는 PLGA/inorganic filler matrix는 생체친화성 및 생체흡수성이 우수한 재료로서 치주 조직의 재생 치료에 있어서 신체활성인자의 scaffold로 사용될 수 있는 가능성을 보여주었다.

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Immunohistochemical study on expression of mast cell and macrophage in irritation fibroma (자극성 섬유종에서 비만 세포와 대식 세포의 면역조직화학적 발현)

  • Han, Hye-Yeon;Kang, Nam-Kyu;Ryu, Mi-Heon
    • Journal of Korean society of Dental Hygiene
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    • v.13 no.1
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    • pp.174-180
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    • 2013
  • 연구목적 : 자극성 섬유종은 만성자극에 의해 발생하는 구강내 증식성 병변이다. 상처치유의 초기 과정에서는 비만 세포와 대식 세포가 섬유모세포의 이주, 증식, 아교질합성 등에 연관되어 있는 성장인자와 사이토카인을 분비하여 상처 치유에 중요한 역할을 한다. 저자들은 자극성 섬유종을 조직학적 특성에 따라 세분하고, 각각의 조직학적 아형에서 비만 세포와 대식 세포의 발현을 조사하여 자극성 섬유종의 발생 기전을 이해하고자 하였다. 연구방법 : 본 연구에서는 82예의 자극성 섬유종을 조직 소견에 따라 4가지 유형으로 분류하였으며, 자극성 섬유종과 10예의 정상 구강점막에 톨루이딘 블루 염색과 CD 68 면역조직화학염색을 시행하였다. 이를 통계화하여 자극성 섬유종의 조직학적 아형에 따른 비만 세포와 대식 세포의 분포 정도를 관찰하였다. 연구결과 : 통계 결과 비만 세포와 대식 세포의 분포는 자극성 섬유종에서 현저히 증가하였으며, Spearman 상관계수는 0.693이었다. 결론 : 조직의 섬유화에 관여하는 비만 세포는 자극성 섬유종의 cellular type에서 유의하게 증가하였으며, 대식 세포도 자극성 섬유종의 모든 아형에서 유의하게 증가하였다. 따라서 자극성 섬유종의 형성 과정에는 비만 세포와 대식 세포의 증가가 중요한 역할을 하는 것으로 생각되었다.

Effects of Forest Healing Programs Using School Forests on Language Acquisition and Ego-resilience of Multicultural Background Students (학교 숲을 활용한 산림치유프로그램 활동이 다문화배경 학생들의 언어습득 향상과 자아탄력성에 미치는 영향)

  • Jang, Cheoul-Soon;Shin, Chang-Seob;Jang, Byung-Soon;Sharif, Md. Omar
    • Korean Journal of Environment and Ecology
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    • v.33 no.3
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    • pp.333-340
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    • 2019
  • As the number of students in the multicultural background grows, the interest in their education is also increasing. The purpose of this study is to investigate the effect of forest healing factors on the improvement of language ability and ego-resilience of students from multicultural families. We conducted an after-school forest healing program of ten male and ten female middle school students of a multicultural preparatory school located in ${\bigcirc}{\bigcirc}$-dong in Cheongju, Chungnam Province. The experiment consisted of a total of 12 weekly one-hour (60 minutes) programs from April 12, 2018 to June 26, 2018. The forest healing program is an activity that uses the various environmental factors that exist in the forest to increase the immunity of the human body and restore physical and mental health. To determine the difference in ego-resilience before and after the program, we conducted a paired t-test and analyzed with the SPSS 18.0 program. The results showed that the ego-resilience significantly improved in all sub-factors including the positive thinking ability, problem-solving ability, intimacy ability, emotional adjustment ability, and autonomic behavior ability (p<.001). The descriptive statistics of the language ability showed the improvement in writing errors, pronunciation errors, sentence errors, tense errors, and errors in research and connection. We expect the results of this study can be used as the basic data to improve ego-resilience and language acquisition ability of middle-entry children and students from multicultural families.

The Effect of EGF, T3 and HB-EGF on Human Periodontal Fibroblasts (EGF, T3, HB-EGF 가 치주인대섬유모세포에 미치는 영향)

  • Hong, Eun-Kyoung;Cha, Jeong-Heon;Kim, Yun-Tae;Choi, Byung-Jai;Kim, Seong-Oh
    • Journal of the korean academy of Pediatric Dentistry
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    • v.34 no.3
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    • pp.438-446
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    • 2007
  • Viable cells of periodontal ligament would be an important factor for the successful replantation of an avulsed tooth. Therefore, it is critical to choose the storage medium for the preservation of traumatically avulsed teeth. Growth factors and hormones could be considered for the therapeutic application of the maintenance of viable periodontal ligament fibroblasts (PDLFs). Epidermal growth factor (EGF) has been suggested as an important player for the regeneration and wound healing process on other tissues. Therefore, EGF was evaluated for the therapeutic application on avulsed teeth. In addition, the synergic effect of EGF with tri-iodothyronine (T3) and heparin-binding epidermal growth factor-like growth factor (HB-EGF). The cell proliferation of PDLFs was determined by MTT assay and increased dose-dependently up to 10 ng/ml in the presence of EGF. Maximum cellular growth was shown at the concentration of 10 ng/ml EGF. Also, EGF promoted the wound healing of PDLFs examined by in vitro wound healing assay. Combined effects of EGF with T3 or HB-EGF on the proliferation of PDLFs were also studied. Interestingly, EGF showed the synergic effect on the proliferation of PDLFs with T3 and HB-EGF. To find out the mechanism of the synergic effect of EGF and T3, the effect of T3 on the expression of endogenous EGF receptor was determined by RT-PCR. The result was that T3 enhanced the expression of EGF receptor in PDLFs. It suggested that EGF might be a good choice for a therapeutic application, which can be used as combination with T3 and HB-EGF.

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Arthroscopic Repair of Full Thickness Tear of The Supraspinatus; Evaluation of the Clinical Outcome and the Postoperative Rotator Cuff Integrity (견관절 극상건 전층 파열의 관절경적 복원술; 임상적 결과 및 술후 회전근개 상태의 평가)

  • Noh, Kyu-Cheol;Chung, Kook-Jin;Kim, Sung-Woo;Yoo, Jung-Han
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.5 no.1
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    • pp.50-57
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    • 2006
  • Purpose: The purpose of this study was to evaluate the tendon healing of arthroscopic repair in full-thickness supraspinatus tears. We evaluate the effectiveness of the arthroscopic repair of full-thickness supraspinatus tears by assessing functional improvement. Materials and Methods: Thirty consecutive full-thickness supraspinatus tears were repaired arthroscopically in 19 patients with a one row of anchor and 11 patients with two rows of anchors. Patients ranged in age from 51 to 79 years (average 63 years). Average follow-up was 16 month (range, 12 to 28 months). To evaluate the effectiveness of the arthroscopic repair of full-thickness supraspinatus tears by assessing functional improvement, we calculate the Constant, ASES, UCLA scores. The 30 patients had either an MR Arthrogram (25 cases) or an MRI (5 cases), performed between 5 months and 20 months (mean 10 months) after surgery. Results: The cuff was healed in 21/30 cases (70%) and partially torn in 3 cases (10%) after the arthroscopic repair of full-thickness supraspinatus tear. Although the supraspinatus tendon was totally torn to the tuberosity in 6 cases(20%) after the arthroscopic repair, the size of the tear was smaller than the initial in 5 cases. The Constant score improved from an average of $55.7{\pm}7.1$ points preoperatively to $77.7{\pm}9.7$ points at the last follow-up (p<0.001), and the average ASES score improved from $39.2{\pm}7.4\;to\;72.4{\pm}12.6$ (p<0.001), and the average UCLA score improved from $17.9{\pm}2.2\;to\;26.8{\pm}5.0$ (p<0.001). Strength of elevation was significantly better $(7.1kgs{\pm}2.4)$ in the shoulders with a healed tendon that in those with an total or partial re-tear tendon $(4.5kgs{\pm}1.0)$ (p<0.05). Factors adversely affecting tendon healing were increasing age, Only 41.7% of the repairs completely healed in patients over 65 years (p<0.05). Conclusion: Arthroscopic repair of isolated full-thickness tear of the supraspinatus leads to completely healing in 70% of the cases. Total or partial re-tear of the repaired rotator cuff is associated with a decreased strength. Older patients had significantly lower healing rates.

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