• Pediatric Infection and Vaccine
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• v.25 no.3
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• pp.165-169
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• 2018

Sepsis and meningitis caused by Neisseria meningitidis are rare in neonates, but neonatal sepsis and meningitis are associated with a high rate of mortality. Meningococcal disease is commonly reported in older children and adolescents and is known to be more prevalent in community settings. In this study, a 16-day-old neonate was diagnosed with serogroup B meningococcal sepsis and meningitis. The baby was treated with antibiotics at the early stages of the infection and was discharged in good condition without any complications. This case report can serve to raise awareness of the incidence and importance of meningococcal infection in neonates, especially serogroup B.

• Journal of Acupuncture Research
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• v.20 no.3
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• pp.209-216
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• 2003

목적 : 대표적인 motor neuron disease(MND)이면서 가장 치명적인 신경퇴행성 질환인 ALS의 발생 양상과 한방치료효과에 대하여 연구하였다. 방법: 상지대학교 부속 한방병원에 래원한 ALS 환자들의 성별, 연령, 발병일, 발병양상, 래원 당시의 병태양상 등을 분석하였고, 이 중 3개월 이상 입원치료를 통하여 치료과정 평가가 가능하였던 18명의 환자들의 치료 전과 치료 후의 변화양상을 평가하였다. 결과 : 외국의 보고에 비하여 여성 환자가 많았고 발병 연령도 유의하게 낮았으며 상지에서 최초의 증상이 발현되는 비율이 상대적으로 높았다. Bulbar From의 비율도 높았고, 대부분의 환자가 여성인 것도 특이하였다. 환자들이 생각하는 질병의 발생원인 중 약 80%가 stress나 정신적 충격 등을 지적하여 정신적 불안상태가 유관함을 추정할 수 있었다. 한방치료가 ALS를 호전시키지는 못하였으나 진행을 억제하였고, 국소적인 주소증을 완화시키며 심리적 안정 상태를 유지하는데 도움이 된다고 평가되었다.

• Proceedings of the Microbiological Society of Korea Conference
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• 2001.11a
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• pp.77-81
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• 2001

Microsporidia in humans emerged with the AIDS epidemic. Enterocytozoon bieneusi is the most significant species' and causes chronic diarrhea, wasting, papillary stenosis, acaculous cholecystitis, bile duct dilatation and sclerosing cholangitis and is responsible for $30-50\%$ of all cases of in people with AIDS. Microsporidiosis has been reported in immunosuppressed, and in immunologically normal individuals. Variety of study has revealed the mode of transmission and possible reservoir of E. bieneusi. Its sites of infection suggest that transmission occurs by ingestion. Transmission has been speculated to occur via infected animals to human, person to person. There is evidence that E. bieneusi occurs in pigs, monkeys, and possibly other animals such as cattle, dogs, cats, llamas and rabbits. E. bieneusi from infected humans has been transmitted experimentally to macaques and to pigs. These observations reflect indirectly the zoonotic nature of E. bieneusi and indicate that cross species transmission is a real possibility. Meanwhile, In recent report, thirty-two percent of the pigs were found to be positive with rates higher over the summer months in US.

• Korean Journal of Environmental Biology
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• v.21 no.3
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• pp.292-296
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• 2003

Effects of aybusculayr mycorrhizal fungus (aMF), Glomus manihot, on plant growth and nutrient uptake on pepper (Capsicum annuum L.) seedlings were evaluated in the nursery experiment. Five different strains of pepper, Chungok, Shingang, Manitta, Gonggongchil, and Shintaeyang, were used in this study. Total fresh weight, nutrient (nitrogen, phosphate and potassium) uptake were increased in all strains inoculated with G. manihot alone and G. manihot and rock phosphate over control at 2 weeks after seeding. Plant weight and phosphate uptake in plants treated with AMF were significantly higher (P< 0.05) than those of control at 6 weeks after seeding. The treatment with G. manihot and rock phosphate gave better plant performance than the treatment with G. manihot alone at 6 weeks after seeding. The lengths of pathogenic symptom on pepper by Phytophthora capsici were reduced significantly by the inoculation of G. manihot spores, Therefore, it would be expected that AMF can be used as the biocontrol agent on pathogens in pepper.

• Fire Science and Engineering
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• v.24 no.5
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• pp.68-78
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• 2010

The purpose of this study, fire officials during the field activities find causes fugitive dust of containing asbestos is the seriousness of the phenomenon is a threat case and through questionnaires, during on-site activities to prevent exposure to asbestos is effectively. Analysis of the relationship to field activities of fire officials and about the dangers of asbestos dust, asbestos cancer caused by asbestos, and to protect fire officials from the same disease like malignant mesothelioma, by varying the conditions of irrational, fire officials at the scene activities in advance of a deadly hazard is aimed to eliminate through optimization of organizational management and a safe and pleasant working conditions for fire officials through the deadly hazards at the scene of action is aimed to obviate. Also according to asbestos exposure by wearing protective equipment as well as thoroughly strengthen firefighting, firefighting awards to recognize the seriousness of the hazard factors, disease and provide compensation to the legal system, for diseases not yet recognized officially recognized by disaster supplemented by institutional, fire officials to improve morale and working conditions, etc. versus expectations is to improve public services.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.6
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• pp.795-801
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• 2020

In the event of a fatal infectious disease in the country, it is very important that the government respond quickly and prevent the secondary infection of the people to prevent the subsequent spread of damage. However, in order to detect infectious diseases in existing medical institutions, and to reach the KCDCP(Korea Centers for Disease Control and Prevention) a total of four steps must be taken. In this paper, we simplifies the existing reporting process using the open blockchain. In addition, not only infectious disease related organizations share infectious disease information on the blockchain, but also grant access to the blockchain to ordinary citizens. By sharing information quickly and transparently revealing the process, we can add credibility to the response to the outbreak and official announcements. The public can also build efficient next-generation defense systems by checking information on the blockchain to prevent secondary infections.

• Korean Journal of Adult Nursing
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• v.20 no.1
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• pp.149-162
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• 2008

Purpose: The purpose of this study was to understand the meanings and nature of ICU admission experienced among patients with critical illness. The present study adopted a hermeneutic phenomenological method which was developed by van Manen. Methods: The participants for this study were 6 men and 3 women, who were over the age of 20 with ICU admission period more than 3 days. Data were collected by using in-depth interviews and observations from March, 2007 to September, 2007. The contents of the interviews were tape-recorded with the consent of the subject. Results: The essential themes that fit into the context of the 4 existential grounds of body, time, space and other people were as follows: a body that cannot react the way it wants, a wave of fear and insecurity everywhere, a struggle to survive, coming out from death's door, loss of time path, a long and continued waiting until escaping, more of machinery room than a patient's room, existence of life and death, an abyss of suffering seen thru another patient, taken care of by a doctor, trust and distrust, family, the ultimate safe zone. Conclusion: Critically ill patients in ICU experienced feelings of discomfort, unsafety, and insecurity. The result of this study can give nurses some insight into these experiences and help promote empathetic care.

• 건강소식
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• v.26 no.12 s.289
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• pp.6-13
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• 2002

뇌졸중, 심근경색 등의 심혈관질환은 암과 더불어 우리나라의 주요 사망원인이다. 2002년 통계청이 발표한 2001년 사망원인통계를 보면 인구 10만명 당 암이 123.5명으로 1위, 뇌졸중 등 뇌혈관 질환이 73.8명으로 2위, 심장질환(허혈성 심장질환과 기타 심장질환 포함)이 34.2명으로 3위였다. 이러한 심혈관질환의 예방을 위해서는 평소 뇌혈관질환을 일으킬 수 있는 위험인자들을 잘 관리할 필요가 있다. 사망률이 높은 심혈관질환의 주요 위험요인은 성별, 연령 등 선천적으로 타고나는 고정요인과 흡연, 비만 등 본인의 노력에 따라 생활습관을 바꿔 위험을 낮출 수 있는 변동요인으로 나눌 수 있다. 성별, 연령은 바꿀수 없지만 생활습관은 바꿀 수 있다. 심혈관 질환 예방에 있어서 가장 중요한 것은 기본적인 건강관리 수칙인 금연, 과음하지 않기, 균형있는 올바른 식생활, 규칙적인 운동, 표준체중 유지하기, 정기검진 등이다.특히 심혈관 질환은 채소류와 식물성 단백질, 식물성 지방 등을 위주로 한 식이요법이 도움을 줄 수 있고 튼튼한 혈관을 가지기 위해서 질 좋은 단백질과 비타민ㆍ무기질을 충분히 섭취해야 하며 콜레스테롤의 배설을 돕기 위해 섬유소가 충분한 식사를 한다. 갑자기 추워진 날씨로 생명을 다투는 뇌졸중이나 협심증, 심근경색 등 심혈관 관련 질병이 발생하기 쉬운 겨울철이다. 행사가 많은 연말에 과음을 삼가며 금연하고, 평소 담백한 한식 위주의 식사, 꾸준한 운동 등으로 건강관리에 힘써서 치명적인 심혈관 질환에 미리미리 대비하도록 한다.

• Proceedings of the Korea Contents Association Conference
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• 2018.05a
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• pp.347-348
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• 2018

일본 뇌염 바이러스(Japanese encephalitis virus)는 작은빨간집모기(Culex spp.)를 매개로 사람에게 감염될 수 있으며, 인체에 치명적인 질병을 유발한다. 일본 뇌염 바이러스의 혈청형(serotype)은 1종류이지만, 유전형(genotype)은 5종류(GI, GII, GIII, GIV, GV)로 분류되고 있다. 현재 일본 뇌염 바이러스 백신은 아시아 지역에서 감염 빈도가 높은 유전형 3(GIII)에 대한 백신이며, 사백신(inactivated vaccine)과 약독화 백신(attenuated vaccine)이 주로 사용되고 있다. 본 연구에서는 기존 백신의 부작용을 줄이고 한계점을 개선하기 위하여, 생물정보학 데이터베이스를 활용한 접근법을 통해 펩타이드 백신 후보군을 선별하였다. 5가지의 유전형 중에서도 감염 빈도가 가장 높은 유전형 3(GIII) 및 최근 감염빈도가 서서히 늘어나고 있어 주의가 요구되고 있는 유전형 1(GI)을 연구 대상으로 선정하였다. 여러 종류의 생물정보학 데이터베이스를 활용하여 백신으로 활용가치가 높은 것으로 보고되고 있는 외피 단백질(envelope protein)에 대한 아미노산 상동성을 분석하고, 이를 바탕으로 공통 적용이 가능한 동시에 면역원성이 높은 펩타이드 3종을 백신 후보군으로 선별하였다. 더 나아가 이들의 3차원 구조 모델링을 통해 보다 백신으로 활용 가능성이 높은 펩타이드를 최종 도출하였다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.12
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• pp.1815-1819
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• 2009

Based on the soft and rigid extents, tissues are mainly divided into two groups in mammals, soft tissues including heart, lung, kidney and brain, and hard tissues including tendon, cartilage, teeth and bone. Among various tissues, bone, a dynamic rigid organ, is continuously remodeled by the opposing functional activity between bone formation by osteoblasts and bone destruction by osteoclasts. Bone protects the soft tissues and provides mineral reservoirs, which can supply the mineral needs of other soft tissues to normally maintain cellular function. While calcification in bone is an important action to fundamentally support the body and protect the soft tissues, calcification in soft tissues, including the heart, aorta, kidney, lung and spleen, results in severe organ damages, eventually causing sudden death. A growing body of evidence indicates that the osteoporotic patient who are aging, post-menopausal, diabetes and chronic kidney disease simultaneously represent a high clinical incidence of soft tissue calcification, illustrating a link between soft tissue calcification and bone decalcification (osteoporosis). This study will review what is currently known about the connection between bone decalcification and soft tissue calcification.