• Communications for Statistical Applications and Methods
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• v.5 no.2
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• pp.447-458
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• 1998

본 논문에서는 환자의 수명과 치료횟수의 모형화를 위해 관측가능한 공변량을 포함하는 동시에 두 변수에 영향을 미치는 관측불가능한 환경요인을 고려하기 위한 개별환경효과모형을 도입하고자 한다. 개별환경효과를 나타내는 분포를 감마분포로 가정하여 사망시간과 치료횟수의 모형을 개발하고, 모형에 포함된 모수의 추론과정을 논의하며, 개발된 모형을 Autologous Blood and Marrow Transplant Registry(ABMTR)에 등록된 환자의 자료에 적용하여 환경효과를 고려하지 않은 독립모형과 비교하고자 한다.

• The Journal of Korean society of community based occupational therapy
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• v.1 no.2
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• pp.71-79
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• 2011

Objective : This study aimed to systematically reviewed to identify, evaluate, synthesize the research literature and suggested to the research direction on the effectiveness of occupational therapy using a sensory integration approach. Methods : We analyzed 10 studies that identified the effectiveness of occupational therapy using a sensory integration approach for children and adolescents offering in MEDLINE/PubMed and http://ajot.aotapress.net between 1993 and 2011. Results : The subjects were the sensory modulation disorder and autism spectrum. The different intervention strategies were similar to a previous studies. Intervention dosage was over 20 sessions, 2~3days per week more than 10weeks. Occupational therapy using a sensory integration approach may result in positive outcome in motor performance, behavioral outcomes, academic and psychoeducational outcomes and tried to currently identify the effect of intervention outcomes in sensory processing and occupational performance using the GAS. Conclusion : Clinicians have a minimal idea planing a research design and a evidence running a study.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.2
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• pp.95-106
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• 2007

The purpose of this study was to investigate effect of spectacle correction therapy instead of occlusion therapy for refractive amblyopia treatment. Spectacle correction were prescribed to give the same effect as a occlusion therapy by under correction for normal eye and there was no additional treatment but only spectacle correction for hyperopic amblyopia. The results can be summarized as follows: 1. In hyperopic amblyopia after correction, initial visual acuity($Mean{\pm}SD$) was $0.36{\pm}0.13$ and final visual acuity($Mean{\pm}SD$) was $0.82{\pm}0.23$. 2. Regardless with age, there was significant differences between initial acuity and final acuity, it shows improvement in visual acuity after spectacle correction treatment. 3. Initial correction age did not influence the length of treatment and success rate of treatment, so that ambyopia correction effect not related with age. 4. Compared with initial visual acuity with final visual acuity, initial visual acuity was in proportion to final visual acuity. 5. Incidence was higher in hyperopia and hyperopic astigmatism than myopia and myopic astigmatism in refractive amblyopia group and the therapy was more effective for hyperopia and hyperopic astigmatism than myopia and myopic astigmatism. 6. Treatment was effective even for children who is older than 8 years.

• The Journal of Korean Physical Therapy
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• v.14 no.1
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• pp.139-158
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• 2002

컴퓨터를 이용하여 MEDLINE, AMED, CINAHL과 Cochrane Libra를 검색하여 요통환자를 위한 다양한 형태의 운동치료 효과에 대해서 발표된 연구 보고서 중 1991년부터 2001년 사이에 영문으로 출판된 보고서를 중심으로 본 연구에 합당한 주제를 충족시키는 연구 보고서 40편을 선택하였다. 수집된 자료를 통하여 요통 관리의 운동치료 효과에 대하여 연구하였으며 일반적인 요통환자들만을 대상으로 급성, 아급성, 만성단계로 구분하였다. 실험논문은 수정된 rating system을 이용하여 논문의 질 수준과 연구결과를 측정하였으며 고찰 논문과 관찰 연구는 grading system을 사용하여 주요 연구 결과를 측정하였다. 본 연구의 결과는 운동치료가 통증감소와 기능 향상에 효과적임이 증명되었고, 총괄적으로 타당도를 지지하는 정도는 중등도에 해당되었다. 연구보고서들을 scale system을 통해서 세부적으로 분석했을 때, 상급의 연구 방법론적 질을 충족시켰다. 결과에 따르면 급성, 아급성과 만성요통에 대한 운동치료가 효과적이었다라는 확실한 증거를 나타냈다. 본 연구의 결론은 요통환자에 대한 운동치료는 효과적으로 입증되었으며, 특별히 만성요통환자의 경우에 더욱 더 효과적인 것으로 나타났다. 이러한 결론을 더욱 지지하기 위해서는 더 많은 고질의 연구 논문들이 이루어져야 할 것이다.

• Journal of Korean Traditional Oncology
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• v.28 no.1
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• pp.33-44
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• 2023

목적: 항암유발말초신경병증은 암 환자가 겪는 흔한 항암 부작용이나 현재까지 효과적으로 알려진 치료법은 없다. 본 연구의 목적은 항암유발말초신경병증에 대한 침 치료와 가바펜틴의 병용 요법의 효과와 안전성을 평가하는 것이다. 방법: 항암유발말초신경병증을 겪고 있는 24명의 암 환자를 침 치료 단독군 (AG, acupuncture group)과 침과 가바펜틴의 병용요법군 (CG, combined acupuncture and gabapentin group)으로 무작위 배정하였다. 두 그룹 모두 침 치료는 주 3회, 4주간 수행하였다. 병용 요법군은 침 치료와 더불어 1일 900mg의 가바펜틴을 복용하도록 하였다. 치료 효과는 Neuropathic Pain Symptom Inventory (NPSI), visual analogue scale (VAS), European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 items (EORTC-CIPN20)를 이용하여 측정하였다. 치료로 인한 부작용은 대상자가 방문할 때마다 조사하였다. 결과: 총 23명의 대상자(AG, n=12; CG, n=11)의 평가지표를 분석한 결과, 치료 4 주 후 침 치료 단독군은 NPSI 점수가 44.33±25.04에서 30.58±21.55으로 감소하였고, 병용 요법군은 30.55±25.59에서 18.64±19.42로 감소하였으며, 두 군 모두 통계적으로 유의미하게 감소하였다(p<0.001). VAS점수는 침 치료 단독군에서는 4.79±2.17 에서 3.42±2.49으로 감소하였고, 병용 요법군에서는 3.55±2.07에서 2.73±2.49 로 감소하였다(p<0.05). 치료 효과는 치료 완료 2주후까지 지속되었으며, 두 군간의 유의미한 차이는 없었다. EORTC-CIPN20은 침 치료 단독군은 30.27±18.87에서 20.84±16.35으로 감소하여(p<0.01), 두 군 모두에서 삶의 질이 향상되었다. 결론: 본 연구로 침 치료와 가바펜틴의 병용 요법이 항암유발말초신경병증 환자의 증상 및 삶의 질 개선에 효과적이며 안전한 치료법임을 확인하였다. 그러나 침 치료와 가바펜틴의 시너지 효과에 대해서는 확인 할 수 없었으며, 이를 확인하기 위해 추가적인 연구가 필요할 것으로 사료된다.

• The Journal of Korean Society for School & Community Health Education
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• v.19 no.1
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• pp.127-144
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• 2018

배경 및 목적: 이 연구의 목적은 OECD "더 나은 삶의 지수 2015"에서 34개 국가 중 29위로 평가된 한국인의 주관적 건강(subjective well-being)과 치료적 지지(therapeutic support) 관계에서 장소애착(place attachment)의 매개 효과를 탐색하였다. 방법: 비확률 표본추출 방법을 사용하여 서울 시민들 중 헬스클럽 이용자를 대상으로 설문지 조사를 실시하였으며, 구조방정식 모형분석을 통해 가설을 검증하였다. 결과: 분석 결과 치료적 감독(therapeutic oversight )만이 주관적 건강에 직접적인 영향을 미치는 것으로 확인되었다(B = .281, p < .05). 장소애착의 매개효과를 통해서 검증한 결과 치료적 감독 뿐만 아니라 치료적 증언(therapeutic testimonial)에 대해서도 유의하게 검증되었다(치료적 감독 간접 효과 = .155, p < .05, 치료적 증언 간접 효과 = .175, p < .05). 결론: 연구결과 주관적 건강에 영향을 미치는 것으로 장소애착의 매개효과가 큰 것으로 나타났다. 따라서 서로를 돌보며 회원들 간의 업적을 축하 할 수 있는 장소를 기반으로 한 건강 프로그램을 실행한다면 사회 구성원들의 주관적 건강 향상에 도움이 될 것으로 사료된다.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.3
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• pp.137-142
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• 2007

The purpose of this study was to investigate sole effect of therapy of spectacles correction on the refractive amblyopia. Spectacles were prescribed to give the same effect as the occlusion therapy undercorrecting in the case of hyperopia, and effectiveness of the therapy was compared with occlusion therapy without additional prescription. The results can be summarized as follows: 1. The higher anisometropic power was the lower initial visual acuity was. 2. Anisometropic power did not influence final visual acuity. 3. The latter beginning time of therapy was the higher astigmatism was. 4. Therapy of spectacles correction on the hyperopic amblyopia was quite effective.

• Horticultural Science & Technology
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• v.28 no.4
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• pp.701-707
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• 2010

To analyze the effectiveness of horticultural therapy reported in research papers, a meta-analysis was carried out with 108 of 377 Korean and overseas research papers on horticultural therapy from 1985 to February 2009 (196 Korean dissertations, 113 Korean journal articles, 5 overseas dissertations, and 63 overseas journal articles). The results revealed a large effect size of 0.71. The effectiveness according to the type, age and number of participants were also analyzed. The therapy was most effective in children, and it was more beneficial for children with special needs and elderly people affected by dementia than for the typical population. The greatest effect was found with group sizes of five people or less, and when carried out by researchers from departments related to horticultural therapy than by researchers from unrelated fields of study. The most effective horticultural therapy programs involved floral decorations; and participants who took part in 21 to 30 sessions or at least 31 sessions benefited the most. Among the main effects of short-term horticultural therapy are cognitive, social, physical and emotional; the greatest effect was observed in the physical domain.

• Radiation Oncology Journal
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• v.17 no.2
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• pp.141-145
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• 1999

Purpose : Granisetron is a potent, the most selective 5-HT3 receptor antagonist and is reported to b effective in treatment of radiation-induced emesis. The antiemetic efficacy and safety of oral granisteron was evaluated in patients with receiving highly emetogenic treatment by conventional fractionated irradiation. Materials and Methods : Patients with various cancers who were being treated with irradiation were accrued into the present study. The intensity of nausea was evaluated on first 24 hours and on day-7 by patients according to the degree of interference with normal daily life as followings; a) none; b) present but no interference with normal daily life (mild): c) interference with normal daily life (moderate): and d) bedridden because of nausea (severe). Non or mild state was considered to indicate successful treatment. The efficacy of antiemetic treatment was graded as follows; a) complete response; no vomiting, no worse than mild nausea and receive no rescue antiemetic therapy over the 24h period, b) major response; either one episode of vomiting or moderate/severe nausea or had received rescue medication over 24h period, or any combination of these, c) minor response; two to four episodes of vomiting over the 24h period, regardless of nausea and rescue medication, d) failure; more than four medication. The score of the most symptom was recorded and the total score over 24 hours was summarized. The complete or major response was considered to indicate successful treatment. Results : A total of 10 patients were enrolled into this study, and all were assessable for efficacy analysis. Total nausea control was achieved in 90$\%$ (9/10:none=60$\%$ plus mild=30$\%$) of total patients after 7 days. The control of vomiting by granisteron was noted in seven patients (70$\%$) of complete response and three (30$\%$) of major response with a hundred-percent successful treatment over 7 days. The minor response or treatment failure were not observed. No significant adverse events or toxicities from granisetron were recorded in patient receiving granisetron. Conclusion : We concluded that granisetron is a highly effective antiemetic agent in controlling radiotherapy-induced nausea or vomiting with a minimal toxicity profile.

• Journal of Music and Human Behavior
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• v.9 no.2
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• pp.1-17
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• 2012

The purpose of this study was to analyze data regarding the effects of group music therapy with adolescents. 27 master's, doctorial theses and published articles between 2000 and 2012 were selected for meta analysis. Subjects, independent variables, dependent variables, and the number of session were used to compare the effectiveness of group music therapy program. 49 effect sizes using means and standard deviation from 27 studies were calculated. The results were as follows. The overall mean effect size was -0.14, which is small size effect, according to Cohen's ES interpretation criteria. The mean ES was influenced by the subjects(adolescents/maladjustment students/addictive students/students in facility), the ES of adolescents was the biggest. However there were no significant difference among subjects. During the independent variables(active music therapy/receptive music therapy/combined music therapy), combined music therapy showed the biggest efficacy. When results were sorted by the dependent variables (social/emotional/behavior/cognitive category), the ES of behavioral category was the biggest. However, there was no significant difference among them. The ES of 11~15 session was the most effective.