• 대한통합의학회지
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• 제8권2호
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• pp.11-20
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• 2020

Purpose : The purpose of this study was to research the effects of dual-hemisphere transcranial direct current stimulation (dual tDCS) and modified constraint-induced movement therapy (mCIMT) to improve upper extremity motor function after stroke. Methods : The study period was from August 2019 to November 2019, and included 24 patients who met the selection criteria. Participants were divided into 2 groups: dual tDCS and mCIMT, and sham dual tDCS and mCIMT group. Dual tDCS and mCIMT group performed mCIMT immediately after applying dual tDCS for 20 minutes, and sham dual tDCS and mCIMT group performed mCIMT immediately after applying sham tDCS for 20 minutes without turning on the power source. Total interventions were conducted 5 times per week for 4 weeks, and mCIMT was conducted for 30 minutes per session for both experimental and control groups. Fugl-Meyer assessment (FMA) and Motor Activity Log scale (MAL) were analyzed before and after 4 weeks of intervention. Results : Both experimental and control groups showed significant changes in FMA, Amount of Use (AOU), and Quality of Movement (QOM) of MAL. When the differences between groups was compared using ANCOVA, the experimental group showed a greater improvement in FMA and AOU of MAL than the control group. Conclusion : In order to enhance the effect of improving upper limb function of stroke patients, dual tDCS could be applied to provide more effective treatment in the clinical setting. Further studies will be needed in larger groups of stroke patients, including long-term follow-up, and multi-group comparisons through the establishment of anodal tDCS and mCIMT, cathodal tDCS, and mCIMT groups to clarify the effects of dual tDCS. In addition, research is needed to establish a protocol for tDCS, and this evidence-based intervention protocol is expected to be used in the clinical setting as an interventional method for various purposes.

• 한국산학기술학회논문지
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• 제14권6호
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• pp.2812-2818
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• 2013

한의학과 대체의학은 그 뛰어난 진단 기술 및 처방과 치료 효과에도 불구하고 선호도에 있어 서양의학에 많이 떨어지고 있는 것이 현 실정이다. 마찬가지로 한의학과 밀접히 연계되어 있는 대체의학도 그 효과에 대한 입증이 과학적으로 규명이 되지 못하고 있는 것이 가장 큰 단점으로 여겨진다. 본 논문에서는 대체의학에서 흔히 사용하는 이침 요법이 실제 인체 장기 기능 강화에 도움이 되는 행위인지를 생체신호를 분석하는 방법 중 얼굴의 피부색 변화를 살펴보는 망진 이론을 적용하여 이를 규명하는 방법을 제안하고자 한다. 이를 위해 폐 이혈 반사점을 자극한 후의 우측뺨 색상을 측정하여 자극 전과의 비교, 분석 실험을 수행하였다. 또한 검증과 규명을 위해 우선적으로 인체가 폐에 미치는 영향의 분석에 필요한 영상 분석 요소를 파악하였다. 실험 결과, 폐 이혈 반사점 자극에 의해 우측뺨의 a값과 b값이 증가하는 결과가 도출되었다.

• Archives of Plastic Surgery
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• 제36권6호
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• pp.679-684
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• 2009

Purpose: Human lipoaspirate cells are relatively easy to obtain in large quantities without cell culture. The aim of this in vitro pilot study was to determine the effect of cell therapy using uncultured lipoaspirate cells on cell proliferation and collagen synthesis of diabetic fibroblasts, which are the major contributing factors in wound healing. Methods: In order to get diabetic fibroblasts, dermis tissues were obtained from foot skin of diabetic patients who underwent debridements or toe amputations(n = 4). In order to isolate lipoaspirate cells, the same diabetic patients' abdominal adipose tissues were obtained by liposuction. The diabetic fibroblasts were co - cultured with or without autogenous lipoaspirate cells using porous culture plate insert. Initial numbers of the lipoaspirate cells and diabetic fibroblasts seeded were 15,000 cells/well, respectively. For cell proliferation assay, two treatment groups were included. In group I, diabetic fibroblasts were cultured with the insert having no cells, which serves as a control. In group II, the lipoaspirate cells were added in the culture plate insert. For collagen synthesis assay, one additional group(group III), in which diabetic fibroblasts were not seeded in the well and only lipoaspirate cells inside the insert were incubated without diabetic fibroblasts, was included for a reference. Results: One hundred to one hundred sixty thousand lipoaspirate cells were isolated per ml of aspirated adipose tissue. After 3 - day incubation, the mean cell numbers in group I and II were 17,294/well and 22,163/well. The mean collagen level in group I, II, and III were 29, 41, and 2 ng/ml, respectively. These results imply that both cell proliferation and collagen synthesis in the lipoaspirate cell treatment group were 28 and 44 percents higher than in the control group, respectively(p < 0.05). Conclusion: Uncultured lipoaspirate cell autografts may stimulate the wound healing activity of diabetic fibroblasts.

• Journal of Acupuncture Research
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• 제18권6호
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• pp.35-43
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• 2001

Objective : The purpose of this study is to examine the reason of choosing acupuncture and moxibustion at first and the change of preference along with the improvement of the causes of avoiding acupuncture and moxibustion. Methods : As for the methodology of the research, we had a questionnaire survey of the freshmen at Dongguk University in 2000. Out of 3095 freshmen, 2158 students (1170 males and 988 females) replied to the questionnaire and statistical analysis was carried out mainly on the items answered by the respondents. Comparison between groups concerning acupuncture and moxibustion treatment utilized x 2 test. Results : The results of the research are as follows: 1. The most frequent reason of choosing acupuncture and moxibustion initially was that it seemed to be effective, and the second reason was that they were encouraged by acquaintances. 2. The most frequent reason of revisiting acupuncture and moxibustion was that it was proved effective, and the second reason was that it did not induce pains. 3. The most frequent reason of not revisiting acupuncture and moxibustion was it was proved ineffective, and the second reason was that it induced pains. A large part of the respondents who did not revisit said they would do if the reasons of not revisiting were improved. Conclusion : The reasons of choosing acupuncture and moxibustion initially and revisiting appear to be closely related to the efficacy of acupuncture. It was shown that whether it was painful was also a crucial factor in the decisions. Based on the results, we consider that it is required to develop acupuncture manipulations that enhance the efficacy and reduce pains, as well as to invent various innovative acupuncture and moxibustion techniques and instruments.

• 디지털융복합연구
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• 제13권5호
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• pp.297-307
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• 2015

본 연구는 접근성과 의료서비스 품질, 대외적 이미지를 높임으로써 향후 지방의료원이 지역 내 대표의료기관으로서 경쟁력을 확보하고 경영효율성을 향상시키는데 그 목적이 있다. 조사대상은 604명으로 하였으며, 분석방법은 ANOVA, 공분산 구조방정식을 실시하였다. 결론을 보면, 의료기관 선택요인에 대한 고객들의 만족도나 선호도가 인구통계학적 특성별로 유의한 차이가 있다는 결과는 앞으로 지방의료원이 의료서비스 전문화 전략을 수립할 때 주요 고객집단의 욕구에 대한 면밀한 검토가 이루어져야 할 필요가 있음을 시사하고 있다. 또한 지방의료원이 진료비 수준에 대한 치료효과와 타 의료기관에 비해 저렴한 진료비가 경쟁우위를 확보할 수 있는 중요요인으로 이에 따른 이미지 부각과 의료서비스의 질의 향상을 극대화하여 의료소비자들을 유인하는 전략이 필요하다.

• 한국융합학회논문지
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• 제11권9호
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• pp.31-37
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• 2020

본 연구는 뇌졸중 환자에게 과제 지향적 훈련과 진동 자극을 결합한 중재에 경두개 직류 전류 자극을 융합했을 때 상지 기능의 회복에 미치는 영향을 알아보고자 하였다. 총 20명을 대상으로 총 4주간, 주 5회, 30분씩 실시했으며, 경 두개 직류 전류 자극을 융합한 과제 지향적 훈련과 진동자극의 결합 중재의 실험군과 과제 지향적 훈련과 진동자극의 결합 중재의 대조군으로 나누었다. 측정은 손의 기민성과 상지기능의 회복을 측정하였다. 실험군과 대조군은 손의 기민성과 잡기, 쥐기, 큰 동작 움직임에서 유의한 개선을 보였으며(p<.05), 실험군은 손의 기민성과 잡기, 쥐기 동작에서 대조군 보다 유의한 개선을 보였다(p<.05). 중재 전후 효과 크기는 모든 평가 항목에서 작은 효과이상을 보였다. 본 연구 결과를 근거로 하여 임상 환경에서 보다 효과적이고 효율적인 재활 치료를 할 수 있을 것으로 사료된다.

• 한국산학기술학회논문지
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• 제15권2호
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• pp.777-784
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• 2014

본 연구는 애완동물 관련 전공 유무를 기준으로 애견의 선호, 관련 지식, 기능, 역할, 이미지, 용도를 조사하여 집단 간 애견의 인지도를 파악하고자 시행되었다. 이를 위해 농촌, 중소도시, 대도시에 재학 중인 전공자와 비전공자 164명의 고교생과 대학생을 대상으로 설문조사를 실시하고 수집한 자료는 집단 간 차이를 알아보기 위해 $X^2$-test로 유의성을 검정하였다. 분석결과 애견이 반려 및 사역 기능과 심신의 장애를 겪고 있는 환자들의 동물보조치료에 이용되는 기능에서 유의성(p<0.05)을 보여 주었다. 또한 전공 유무에 따라 애완동물과 반려동물의 인지 차이가 매우 크다는 것을 알 수 있었다. 이에 애견의 다양한 용도와 역할의 인지가 확대되어 애완동물을 너머 반려동물로서 그 정체성이 확보되는 정책적 프로그램의 개발과 적용이 필요하다고 판단된다.

• 한국콘텐츠학회논문지
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• 제21권7호
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• pp.144-156
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• 2021

본 연구에서는 상담 및 심리치료 분야에서 대화형 에이전트의 활용이 증가하는 가운데, 음성 기반 심리상담 에이전트 설계 시 중요하게 고려해야 하는 요인을 탐색하기 위해 실험 연구를 진행하였다. 이를 위해 실제 심리상담 맥락에서 음성 기반 대화형 에이전트를 구현하여, 20~30대 성인 남녀 48명을 대상으로 상담 대화를 진행하였다. 연구 참여자는 4가지 유형의 에이전트 목소리(청년여성, 청년남성, 중년여성, 중년남성) 중 선호하는 목소리를 선택한 후 대화하였으며, 목소리 선택에 대한 이유, 기분 변화, 에이전트의 특성에 대한 지각, 상담 성과 등을 평가하였다. 연구 결과, 사용자 성별에 따른 에이전트의 목소리 유형 선택은 통계적으로 유의하지 않았다. 그러나 목소리 선택 이유로 '편안함'이 가장 많이 언급됨으로써, 심리상담 에이전트에게 요구되는 목소리 특성이 탐색되었다. 다음으로, 사용자는 에이전트와의 대화 후, 기분이 유의미하게 개선되는 것으로 나타남으로써 심리상담 에이전트의 개입 효과를 확인하였다. 마지막으로, 사용자가 심리상담 에이전트에게 지각하는 특성 중, 전문성과 호감이 상담 성과를 긍정적으로 평가하는데 중요한 요소임이 확인되었다. 본 연구 결과를 바탕으로 심리상담 에이전트의 활용 가능성과 추후 연구에 대한 제언을 제시하였다.

• 기본간호학회지
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• 제26권3호
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• pp.197-209
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• 2019

Purpose: This study was done to examine good death awareness, attitudes toward advance directives (ADs), and preference for care near the end-of-life (PCEOL) of hospitalized elders in long-term care hospitals. Relevant characteristics were investigated as well as correlation of the variables. Methods: This descriptive research study involved 161 hospitalized elderly patients in long-term care hospitals. A self-report questionnaire was used to measure Good Death Scale, ADs Survey, PCEOL Scale, and general characteristics. Collected data were analyzed using descriptive statistics, t-test, ANOVA, and Pearson correlation with SPSS/WIN 23.0. Results: In terms of good death awareness, a significant difference was observed; in according to age (F=3.35, p=.037), payer of treatment costs (F=3.98, p=.021), mobility (F=3.97, p=.021), heard discussion about ADs (t=-3.89, p<.001), and willing to complete ADs (t=2.12, p=.036). As far as attitudes toward ADs, the participants presented significant difference depending on religion (t=2.38, p=.018), average monthly income (F=3.91, p=.022), duration of hospital admission (F=5.33, p=.006), person to discuss ADs (t=-2.76, p=.006). On PCEOL, there was a significant difference, depending on religion (t=-3.59, p<.001) and perceived health status (F=3.93, p=.022). Finally, as for how the variables were related to each other, good death awareness and attitudes toward ADs had a weak positive correlation with PCEOL. Conclusion: To help seniors staying in nursing homes face a good death and enjoy autonomy, there should be educational and support systems that reflect each individual's sociodemographic characteristics so that the seniors can choose what kind of care they want to receive near the end-of-life.

• 대한통합의학회지
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• 제8권4호
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• pp.107-115
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• 2020

Purpose: This study aims to systematically review the dual-task evaluation applied to the screening of mild cognitive impairment. It also aims to present various evaluation items and results analysis methods for dual tasks applied to patients with mild cognitive impairment. Methods: We conducted a systematic search of published studies in PubMed databases and KISS from January 2000 to August 2020 using the main keywords such as "Dual task," "Mild Cognitive impairment," "Elderly," and "Screening." We selected a total of 10 studies for the analysis from 1314 searched articles. Results: We analyzed the qualitative level of 10 studies that were nonrandomized two-group studies with evidence level II (100.0%). These results suggest that the evidence level of the studies was high. We analyzed 10 studies and identified 12 motor tasks and 19 cognitive tasks. Walking was the most commonly used evaluation motor task and counting backward by ones and naming animals were the most commonly used evaluation cognitive tasks. Moreover, the velocity speed was the most used result analysis method. The results indicate that there were significant differences in dual-task performance between patients with normal and mild cognitive impairment. Conclusion: The results of this study can be used as a basis for the selection of dual-task evaluation items and methods of analyzing the results for screening mild cognitive impairment. Furthermore, they are expected to be used for research on the development of dual-task evaluation tools. It is necessary to compare and analyze the usage trends of dual-task evaluation by cultural differences in future studies.