• Journal of the Korean Applied Science and Technology
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• v.39 no.1
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• pp.1-9
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• 2022

1, 2-Octanediol (OD) as a cosmetic additive has been used simultaneously as a preservative and humectant. To solve the skin problem by 1, 2-octanediol (OD), we have synthesized 1, 2-octanediol galactoside (OD-gal) using Escherichia coli β-galactosidase (β-gal). Meanwhile, the optimal amount of β-gal, OD concentration, pH, and temperature for OD-gal synthesis were 4.5 U/ml, 150 mM, 7.0, and 37℃, respectively. Under these conditions, 150 mM OD was converted into about 55.9 mM OD-gal during 24 hours, in which the conversion yield (mole basis) was about 37.2%. In addition, OD-gal of 67.4 mg could be purified from a 9 ml reaction mixture, in which the overall synthesis yield from OD to the purified OD-gal was about 34.1% (weight basis) and 16.2% (mole basis), respectively. We are expecting that these results will be helpful to develop a safer additive in the cosmetic industry as basic data.

• Korean Journal of Food Science and Technology
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• v.27 no.4
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• pp.564-570
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• 1995

N-Benzoyl-L-aspartyl-L-phenylalanine methyl ester(BzAPM), a novel aspartame precursor, was investigated for its enzymatic synthesis by immobilized thermolysin using a water-miscible organic solvent system. The substrate used were N-benzoyl-L-aspartic acid(BzAsp) and L-phenylalanine methyl ester (PheOMe). Synthetic conditions such as substrates concentration, temperature, pH, and some metallic ions were varied to study their effects on BzAPM synthesis. The synthetic reaction rate increased linearly as the PheOMe concentration increased at a constant concentration of BzAsp(100 mM), and the maximum reaction rate was obtained at BzAsp concentration of 200 mM when 300 mM PheOMe was used. The optimum pH and temperature were found to be 6.1 and $40^{\circ}C$, respectively. The metallic ions such as $Zn^{2+},\;Mg^{2+},\;Mn^{2+},\;Fe^{2+},\;Pb^{2+}\;and\;Cu^{2+}$ at 5 mM level showed inhibitory effect on BzAPM synthesis, while $Co^{2+}$ and $Ca^{2+}$ ion increased synthesis. $Co^{2+}$ ion was also found to have synergistic effect with $Ca^{2+}$ ion. Benzoic acid, L-phenylalanin and NaCl showed inhibitory effect.

• Journal of the Korean Applied Science and Technology
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• v.36 no.2
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• pp.572-580
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• 2019

Recently, it has been reported that benzyl alcohol (BzOH) as an additive in cosmetics, food, and medicine lead to toxicity and allergy problem. Then, to circumvent this hurdle, we carried out the synthesis of benzyl alcohol galactoside (BzO-gal). Previously, it was confirmed that BzO-gal was synthesized by transgalactosylation reaction using Escherichia coli (E. coli) ${\beta}$-galactosidase (${\beta}-gal$). Meanwhile, in this study, two peaks of BzO-gal as sodium adduct ion (m/z=293.1004) and protonated ion (m/z=271.1180) were detected in the reaction mixture by liquid chromatography/electrospray ionization mass spectrometry (LC/ESI-MS). In addition, the amount of ${\beta}-gal$ and BzOH concentration, temperature, pH, and lactose concentration, respectively, were optimized (${\beta}-gal$, 0.75 U/mL; BzOH, 185 mM; temperature, $40^{\circ}C$, pH, 7.5; lactose, 350 g/l). Under these optimal conditions, 185 mM BzOH was converted into about 131 mM BzO-gal, in which the conversion yield was about 72%. In the future, BzO-gal will be applicable as a substitute for BzOH as a less toxic preservative for the cosmetic, pharmaceutical, and food industries, and we are planning to investigate the characteristics of BzO-gal as a preservative.

• 한국신재생에너지학회:학술대회논문집
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• 2007.06a
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• pp.792-795
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• 2007

본 연구 목적은 석탄 가스화를 통해 얻어진 합성가스를 이용하여 국내에서 개발된 DME 합성 촉매를 사용하여 DME 전환 공정에 대한 특성을 파악하는 것이다. 특히, DME 합성 반응에 가장 큰 영향을 미치는 합성 반응로의 온도 제어를 위하여 thermosyphon 시스템을 개발하여 DME 합성 반응에 최적온도로 알려진 $230{\sim}260^{\cdot}C$ 범위에서 제어가 가능함을 확인 하였다. 석탄 40 kg/h를 공급하였을 때 합성가스 유량은 $80{\sim}100$ $Nm^3/h$ 정도를 얻었다. DME 합성 반응에 사용한 촉매는 합성가스로부터 메탄올을 얻기 위한 촉매와 메탄올의 탈수 촉매(Cu/Zn/Al+r-$Al_2O_3$)를 혼합한 촉매를 사용하였다. DME 합성 반응로의 GHSV(1/kg$^{\cdot}C$cat h)는 $2500{\sim}3000$ 정도이며, 운전 압력 60기압에서 $H_2$ 전환율 $65{\sim}75%$, DME 선택도는 $69{\sim}79%$ 정도를 얻었다.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.5
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• pp.535-541
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• 2015

In this study, an approximate multi-objective optimization of a wall-mounted monitor bracket arm was performed. The rotation angle of the bracket arm was determined considering the inplane degree of freedom. We then formulated an optimization problem on maximum stress and deflection. Analyses of mean and design parameters were conducted for sensitivity regarding performance with orthogonal array and response surface method (RSM). RSM models of objective and constraint functions were generated using central composite (CCD) and D-optimal design. The accuracy of approximate models was evaluated through $R^2$ value. The obtained optimal solutions by non-dominant sorting genetic algorithm (NSGA-II) were validated through the finite element analysis and we compared the obtained optimal solution by CCD and D-optimal design.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.35 no.11
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• pp.1006-1012
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• 2007

In this paper, a suboptimal homing guidance law for the homing missiles with an impact angle constraint is presented. Unlike general LQ optimal control, the aided loop ensuring some degrees of freedom for the constraint is introduced. Then an optimal feedback loop in consideration of the aided loop is designed by using Schwartz inequality. The aided loop is synthesized with the optimal control to produce the guidance command. Furthermore, to investigate the characteristics of the guidance law we carry out the comparative studies with other guidance laws. The results of the various computer simulations show the good performance of the proposed law.

• Proceedings of the Acoustical Society of Korea Conference
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• 1998.06e
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• pp.273.2-277
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• 1998

본 논문에서는 음소단위 비정형 연결합성 시, 접합점에서 포만트 불연속을 최소화할 수 있도록 이웃음소간 경계강도 예측모델과 합성단위 검색시 음소단위 최장일치 검색 알고리즘을 설계하였다. 합성단위 연결부에서 발생하는 신호왜곡을 최소화하기 위해 “_C_”환경에서 자음이 유성음화된 경우, “_V_”환경에서 모음이 무성음화된 경우, 그리고 유성음 사이의 포만트 주파수 차이에 대한 모델을 생성하여, 음소간의 조음강도가 약한 부분이 합성단위 경계로 설정되도록 하였다. 합성단위 경계가 결정되면 주어진 문장의 문맥정보만을 이용하여 코포스로부터 후보를 선택한다. 선택된 후보를 사이의 연결성을 측정하기 위하여 합성 경계를 기준으로 전, 후 음소에 대한 음성적 특성과 포만트 천이 특성을 고려하였다. 실험은 K-ToBI 레이블링된 200문장을 기반으로 하였으며, 코퍼스로부터 한 문장을 선택하여 이를 목적치 패턴으로 선정 한 후, 목적치 패턴과 후보사이의 단위비용과 후보들 간의 연결비용을 계산하여 최적의 합성단위열을 추출하는 방식으로 이루어졌다. 본 논문에서는 이러한 문맥종속 단위 기반의 합성단위 추출 알고리즘과 실험 결과에 대해 보고한다.

• KSBB Journal
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• v.15 no.3
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• pp.268-273
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• 2000

A microbiological hydrogen production process was optimized. Anaerobic photosynthetic bacteria like Rhodospirillum rubrum which is known to produce hydrogen from carbon monoxide efficiently and remove sulfur was used. To evaluate the potenital of this microorganism the optimization of media fermentation condition light intensity and light requirement for CO conversionwas tried in batch cultures and the continuous fermenter was also applied for this process. The gas residence time on CO conversion was sought out to get high conversion of carbon monoxide to hydrogen. Through this study the possibility of microbial synthtics gas concersion process was proposed.

• Journal of Korean Tunnelling and Underground Space Association
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• v.8 no.2
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• pp.129-139
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• 2006

When blasting by imposing the time difference between two adjacent charge holes, the mutual interference phenomenon occurs depending the feature of blast. This interference phenomenon of blast amplifies or compensates the blast-induced vibration depending on the overlapping mechanism. Thus, this experiment aims at finding out the optimum delay time by measuring the blast vibration data from the single hole blast during the blasting test and composing each blasting waveform, and at proving the its efficiency by applying the composition delay time in the entire cross section. The experiment showed that the blasting-induced vibration was reduced by endowing an optimum delay time of electronic detonator appropriate to the rock quality of construction site compared to the typical delay time (20, 25ms) of existing detonator (non-electric and electric detonator). From these results, the excavation efficiency using blasting could be enhanced..

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2015.11a
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• pp.108-109
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• 2015

본 논문은 low-rank 행렬의 truncated nuclear norm 최소화를 이용한 HDR (high dynamic range) 영상 합성 기법을 제안한다. 제안하는 기법에서는 기존의 LDR (low dynamic range) 영상에서 얻은 밝기의 선형 관계에 기반하여 HDR 합성을 low-rank 행렬 완성 문제로 변환한 후, ALM (augmented Lagrange multiplier) 기법을 이용하여 효율적으로 최적의 해를 구한다. 컴퓨터 모의실험을 통해 제안하는 기법이 기존 기법에 비해서 낮은 계산 복잡도를 보이면서도 더 높은 품질의 HDR 영상을 합성하는 것을 확인한다.