• Title/Summary/Keyword: 초크

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Effects of black chokeberry on cholesterol metabolism in HepG2 cells (블랙 초크베리가 HepG2세포에서 콜레스테롤 대사에 미치는 효과)

  • Lee, Sang Gil;Kim, Bohkyung
    • Korean Journal of Food Science and Technology
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    • v.54 no.4
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    • pp.398-402
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    • 2022
  • Black chokeberry (Aronia melanocarpa), a rich source of polyphenols, exerts hypocholesterolemic effects. However, little is known about its effects on the regulation of the hepatic cholesterol metabolism and the underlying mechanisms. In the present study, the effects of polyphenol-rich black chokeberry extract (CBE) on hepatic cholesterol metabolism were investigated by measuring the expression of genes involved in the absorption, de novo synthesis, and efflux of cholesterol in HepG2 cells. There was a significant reduction in the expression levels of genes involved in cholesterol metabolism, the low-density lipoprotein receptor, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and sterol regulatory element-binding protein 2, in CBE-treated HepG2 cells. Meanwhile, CBE increased the expression levels of genes involved in cholesterol and bile acid efflux. The expression levels of mitochondrial fatty acid oxidation genes increased, whereas those of lipogenic genes decreased following CBE treatment. These data suggest that the consumption of black chokeberry may be beneficial for the prevention of hypercholesterolemia.

A Variable Leakage Inductance Common-Mode Choke (누설인덕턴스 가변형 공통모드 초크코일)

  • Baek, Mi-Ran;Kim, Hee-Seung;Won, Jae-Sun;Ju, Jae-Chul;Oh, Dong-Sung;Han, Sang-Kyoo;Hong, Sung-Soo
    • Proceedings of the KIPE Conference
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    • 2011.07a
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    • pp.402-403
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    • 2011
  • EMI 필터 설계 시 주로 사용되는 공통모드 초크의 경우 자화 인덕턴스로부터 공통모드 노이즈 감쇠를, 누설 인덕턴스로부터 차동모드 노이즈 감쇠를 기대할 수 있다. 이때, 누설인덕턴스가 너무 클 경우 차동모드 노이즈 감쇠에는 우수하지만, 전기/전자제품이 슬림화됨에 따라 공통모드 초크의 누설 자속과 전원공급기를 덮고 있는 금속덮개 사이에 자계 간섭에 의한 진동/소음문제가 발생될 수 있다. 본 논문에서는 누설자속을 조절할 수 있는 공통모드 초크의 코어형상 및 권선기법을 제안한다. 제안된 방법은 진동 및 소음을 제어할 수 있는 장점을 지니고 있다.

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The protective effects of polyphenol-rich black chokeberry against oxidative stress and inflammation (폴리페놀 함유 블랙 초크베리의 산화적 스트레스 및 염증에 대한 보호 효과)

  • Jeon, Sohyeon;Kim, Bohkyung
    • Korean Journal of Food Science and Technology
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    • v.52 no.2
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    • pp.138-143
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    • 2020
  • Black chokeberry (Aronia melanocarpa) has been suggested to exert antioxidant and anti-inflammatory effects due to its high polyphenol content. However, the mechanisms underlying the effects of black chokeberry on the alterations of nuclear factor E2-related factor 2 (NRF2) and nuclear factor κB (NF-κB) in macrophages have not been thoroughly studied. In this study, we investigated the protective effects of polyphenol-rich black chokeberry extract (CBE) against lipopolysaccharide (LPS)-induced oxidative stress and inflammation in RAW 264.7 macrophages. CBE significantly attenuated the increase of cellular reactive oxygen species (ROS) levels and the nuclear translocation of NRF-2 in LPS-stimulated macrophages. The mRNA abundances of Nrf2 and its downstream antioxidant genes were significantly decreased in LPS-stimulated macrophages. The LPS-induced mRNA expression of proinflammatory cytokines was significantly inhibited by reducing the nuclear translocation of NF-κB by CBE. These data suggest that black chokeberry may be used for the prevention of oxidative stress and inflammation-associated disease.

Comparison of Total Polyphenols, Total Flavonoids, and Biological Activities of Black Chokeberry and Blueberry Cultivated in Korea (국내산 Black Chokeberry와 Blueberry의 총 폴리페놀, 총 플라보노이드 함량 및 생리활성 비교)

  • Chung, Hai-Jung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.9
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    • pp.1349-1356
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    • 2014
  • This study investigated the biological activities of 70% methanol extracts from black chokeberry and blueberry by measuring DPPH, superoxide anion and ABTS radical scavenging activities, metal chelating effect, reducing power, and nitrite scavenging activity. Extraction yields of black chokeberry and blueberry were 62.90% and 67.09%, respectively. Total polyphenol and total flavonoid contents were 117.20 mg/g and 32.50 mg/g for black chokeberry and 42.26 mg/g and 26.39 mg/g for blueberry, respectively. Black chokeberry had higher antioxidant activity than blueberry. DPPH and ABTS radical scavenging activities, nitrite scavenging activity, and metal chelating effect of black chokeberry were 98.29%, 96.68%, 97.64%, and 91.33%, respectively, at a concentration of 5 mg/mL, which were equal to those of ascorbic acid (positive control). These results suggest that black chokeberry has potent biological activities, and in the future, the availability of black chokeberry will increase in the field of value added food products.

An Analytical Study for Critical Mass Flowrate of Compressed Water (압축수의 임계유량에 관한 해석적 연구)

  • 김희동;김재형;한민교;박경암
    • Journal of the Korean Society of Propulsion Engineers
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    • v.7 no.1
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    • pp.57-65
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    • 2003
  • As a compressed water is rapidly expanded through a nozzle, two-phase flow of vapor and liquid is formed in the nozzle due to the flash evaporation. In the present study, critical flow of two-phase fluids is analysized using an Isentropic-Homogeneous-Equilibrium model and a Leung model. Calculation results show that the choke of the two-phase flow can be two different types of continuous and discontinuous chokings. For the stagnation pressure below 10 Mpa it is found that the continuous choking, which is similar to the choking phenomenon of single-phase gas flow, is possible only when the degree of subcooling is less than 10K.

Optimization of band-stop filter in coaxial line (동축선로내 대역억제필터의 최적화)

  • 정봉식
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.1
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    • pp.97-103
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    • 2000
  • In this paper band-stop filters that reject the undesired 3th and/or 5th harmonics generated from high frequency generator are analyzed using equivalent circuit concept, and optimized using iterative optimization algorithm. The length of the band-stop filter is setup initially a quarter of a wavelength of the harmonic, but initial filter structure is exactly unable to cutoff the harmonics because of the fringing effect at the discontinuous boundary. To reduce the mismatch between the cutoff frequency and the harmonics, iterative LMA(Levenberg-Marquardt Algorithm) is introduced and band-stop filters in coaxial line are optimized.

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A Study on the Characteristics Analysis of Hybrid Choke Coil with Reduced Parasitic Capacitance suitable for LED-TV SMPS (LED-TV용(用) 전원장치에 적합한 기생 커패시턴스 저감형 Hybrid 초크 코일의 특성 해석에 관한 연구)

  • Lee, Jong-Hyeon;Kim, Gu-Yong;Kim, Jong-Hae
    • Journal of IKEEE
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    • v.22 no.1
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    • pp.185-188
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    • 2018
  • This paper describes the parasitic capacitance modeling according to the coil structure, section bobbin and winding method for hybrid choke coil with reduced parasitic capacitance capable of the EMI attenuation of broad bands from lower frequency to higher frequency applied in the EMI attenuation filter of LED-TV SMPS. Especially, the hybrid choke coil with reduced parasitic capacitance($C_p$) proposed in this paper can reduces the parasitic capacitance($C_p$) by adopting the winding methods of rectangular copper wire, compared to the conventional common mode choke coil with the winding method of automatic type. The first resonant frequency of the proposed hybrid choke coil has a tendency to increase as the parasitic capacitance is smaller and its impedance characteristics, especially in the high frequency bands, improves as the first resonant frequency increases. In the future, the proposed hybrid choke coil with reduced parasitic capacitance shows it can be actually utilized in not only LED-TV SMPS but also various applications such as LED Lighting, Note-PC Adapter, and so forth.