• Title/Summary/Keyword: 초점크기

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Prediction Method for Ground Collapse Using Numerical Simulations (수치해석을 이용한 도로함몰 예측기법)

  • Kim, Hee Su;Ban, Hoki
    • Journal of the Korean GEO-environmental Society
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    • v.20 no.9
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    • pp.5-11
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    • 2019
  • Recently, ground collapse in urban area has been widely paid attention as it frequently happens. To investigate the causes and suggest the measurements, many researches such as ground exploration from GPR, mock test and numerical simulations have been conducted. The proposed risk evaluation chart recently focuses only on the current ground status and is not capable of forecasting the ground collapse. This paper presents the prediction method of ground collapse using the numerical simulations of 30 cases considering void size and ground height as variables. It finally provides the charts that can analyze quantitatively the ground collapse.

Virus Purification by Membrane Chromatography: A Review (멤브레인 크로마토그래피에 의한 바이러스 정제 : 리뷰)

  • Gayatri Bhamidipatia;Rajkumar Patel
    • Membrane Journal
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    • v.34 no.2
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    • pp.124-131
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    • 2024
  • Viruses have various applications in the biopharmaceutical industry. They are used in pesticide production, production of vaccines, gene transfers, cancer therapeutics, and more. The downstream processing of viruses is an essential step for their biological and pharmaceutical applications. Among the various processes, the purification of viruses is critical. Membrane chromatography plays a vital role in this process. While ion exchange membrane chromatography is a primarily used method, it has various limitations regarding size exclusion and insufficient purification. Also, it cannot be applied to the rapidly changing strains of viruses such as influenza. This review examines various improved methods of membrane chromatography or alternatives. It focuses on purification, viral recovery rates, and scalability of the methods.

An Analysis of Soil Pressure Gauge Result from KHC Test Road (시험도로 토압계 계측결과 분석)

  • In Byeong-Eock;Kim Ji-Won;Kim Kyong-Ha;Lee Kwang-Ho
    • International Journal of Highway Engineering
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    • v.8 no.3 s.29
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    • pp.129-141
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    • 2006
  • The vertical soil pressure developed in the granular layer of asphalt pavement system is influenced by various factors, including the wheel load magnitude, the loading speed, and asphalt pavement temperature. This research observed the distribution of vertical soil pressure in pavement supporting layer by investigating measured data from soil pressure gage in the KHC Test Road. The existing specification of subbase and subgrade compaction was also evaluated with measured vertical pressure. The finite element analysis was conducted to verify the accuracy of results with measured data because it can maximize research capacity without significant field test. The test data was collected from A5, A7, A14, and A15 test sections at August, September, and November 2004 and August 2005. Those test sections and test data were selected because they had best quality. The size of influence area was evaluated and the vertical pressure variation was investigated with respect to load level, load speed, and pavement temperature. The lower speed, higher load level, and higher pavement temperature increased the vertical pressure and reduced the area of influence. The finite element result showed the similar trend of vertical pressure variation in comparison with measured data. The specification of compaction quality for subbase and subgrade is higher than the level of vertical pressure measured with truck load so that it should be lurker investigated.

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Fabrication of PLGA/Dextran Double-Layered Microspheres by Oil-in-Water Solvent Evaporation Method (O/W 용매 증발법을 이용한 PLGA와 덱스트란의 이중층 미립구 제조)

  • Ko Jong Tae;Lee Jae-Ho;Lee Chang-Rae;Shin Hyung Sik;Yuk Soon Hong;Kim Moon Suk;Khang Gilson;Rhee John M.;Lee Hai Bang
    • Polymer(Korea)
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    • v.29 no.6
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    • pp.543-548
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    • 2005
  • Double-layered spheres play an important role in controlling drug delivery for pharmaceutical application, because of the low initial burst compared with single-layered spheres and targetable delivery to specific organ. But it has drawback in loading drug and controlling size. In this study, we developed double-layered spheres using relatively simple oil-in-water (O/W) solvent evaporation method witw/without ultrasonication and investigated the size variation of the double-layered microspheres on the contents of poly(lactide- co-glycolide) (PLGA). Double - layered spheres were char-acterized by scanning elecron microscope (SEM), camscope, and confocal fluorescence laser microscope (CFLM). Double-layered spheres showed smooth surfaces and obvious difference between core and corona by SEM observation and camscope. We observed the fluorescent core in the double-walled spheres composed of FlTC-dextran and PLGA using CFLM. It was found that the core of the microsphere was dextran and the corona of the fabricate microsphere was PLGA. Also, the more PLGA concentration, the more the size of the fabricating double-layered sphere observed.

Development of the IRIS Collimator for the Portable Radiation Detector and Its Performance Evaluation Using the MCNP Code (IRIS형 방사선검출기 콜리메이터 제작 및 MCNP 코드를 이용한 성능평가)

  • Ji, Young-Yong;Chung, Kun Ho;Lee, Wanno;Choi, Sang-Do;Kim, Change-Jong;Kang, Mun Ja;Park, Sang Tae
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.13 no.1
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    • pp.55-61
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    • 2015
  • When a radiation detector is applied to the measurement of the radioactivity of high-level of radioactive materials or the rapid response to the nuclear accident, several collimators with the different inner radii should be prepared according to the level of dose rate. This makes the in-situ measurement impractical, because of the heavy weight of the collimator. In this study, an IRIS collimator was developed so as to have a function of controlling the inner radius, with the same method used in optical camera, to vary the attenuation ratio of radiation. The shutter was made to have the double tungsten layers with different phase angles to prevent the radiation from penetrating owing to the mechanical tolerance. The performance evaluation through the MCNP code was conducted by calculating the attenuation ratio according to the inner radius of the collimator. The attenuation ratio was marked on the outer scale ring of the collimator. It is expected that when a radiation detector with the IRIS collimator is used for the in-situ measurement, it can change the attenuation ratio of the incident photon to the detector without replacing the collimator.

Nanoemulsions: a Novel Vehicle for Cosmetics (나노에멀젼: 화장품을 위한 새로운 제형)

  • Cho, Wan-Goo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.37 no.1
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    • pp.1-21
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    • 2011
  • This review describes several kinds of emulsification methods for nanoemulsions and the application of nanoemulsions. Nanoemulsion droplet sizes fall typically in the range of 20 ~200 nm and show narrow size distributions. Although most of the publications on either oil-in-water (O/W) or water-in-oil (W/O) nanoemulsions have reported their formation by dispersion or high-energy emulsification methods, an increased interest is observed in the study of nano-emulsion formation by condensation or low-energy emulsification methods based on the phase transitions that take place during the emulsification process. Phase behaviour studies have shown that the size of the droplets is governed by the surfactant phase structure (bicontinuous microemulsion or lamellar) at the inversion point induced by either temperature or composition. Studies on nanoemulsion formation by the phase inversion temperature (PIT) method have shown a relation between minimum droplet size and complete solubilization of the oil in a microemulsion bicontinuous phase independently of whether the initial phase equilibrium is single or multiphase. Due to their small droplet size nanoemulsions possess stability against sedimentation or creaming with Ostwald ripening forming the main mechanism of nanoemulsion breakdown. An application of nanoemulsions is the preparation of nanoparticles using a polymerizable monomer as the disperse phase where nanoemulsion droplets act as nanoreactors, cosmetics and controlled drug delivery. In this review, we mainly focus on the cosmetics.

Load Transfer to the Adjacent Ground Induced by the 3-Dimensional Active Displacement (3차원 주동변위에 따른 인접지반으로의 하중전이)

  • Park, Byung Suk;Lee, Sang Duk
    • Journal of the Korean Geotechnical Society
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    • v.31 no.10
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    • pp.49-60
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    • 2015
  • Since previous studies on the 3-dimensional earth pressure have been conducted focusing on the stability of wall, it is very difficult to find a study on the load transfer to the adjacent ground induced by the 3-dimensional active displacement. Therefore, in this study, we tried to find out the load transfer to the adjacent ground induced by the 3-dimensional active displacement depending on the size of rectangular wall which was defined by the aspect ratio, that is, the ratio of the height to the width of the wall. 3-dimensional model tests were performed in order to measure the distribution and the magnitude of load transfer to surrounding grounds. The transferred load was 17.9~30.6% less than the difference between the 3-dimensional active earth pressure and earth pressure at rest. The transferred load of both vertical and horizontal was maximum at the boundary of the active wall. The load transfer range depended on the normalized height of the active wall, and it was 0.67~1.29w in horizontal direction and 1.0~3.0h in vertical direction. The transferred load in horizontal was maximum at the height of the wall. As the aspect ratio increases the location of the maximum transferred load points becomes higher. The ratio of the transferred load area of 56~79% at 0.25w in horizontal direction and 50~58% at 1.0~1.5 in vertical direction. Diagrams showing the distribution and the magnitude of the transferred load depending on the aspect ratio were suggested.

A Study on the Restoration of a Low-Resoltuion Iris Image into a High-Resolution One Based on Multiple Multi-Layered Perceptrons (다중 다층 퍼셉트론을 이용한 저해상도 홍채 영상의 고해상도 복원 연구)

  • Shin, Kwang-Yong;Kang, Byung-Jun;Park, Kang-Ryoung;Shin, Jae-Ho
    • Journal of Korea Multimedia Society
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    • v.13 no.3
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    • pp.438-456
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    • 2010
  • Iris recognition uses a unique iris pattern of user to identify person. In order to enhance the performance of iris recognition, it is reported that the diameter of iris region should be greater than 200 pixels in the captured iris image. So, the previous iris system used zoom lens camera, which can increase the size and cost of system. To overcome these problems, we propose a new method of enhancing the accuracy of iris recognition on low-resolution iris images which are captured without a zoom lens. This research is novel in the following two ways compared to previous works. First, this research is the first one to analyze the performance degradation of iris recognition according to the decrease of the image resolution by excluding other factors such as image blurring and the occlusion of eyelid and eyelash. Second, in order to restore a high-resolution iris image from single low-resolution one, we propose a new method based on multiple multi-layered perceptrons (MLPs) which are trained according to the edge direction of iris patterns. From that, the accuracy of iris recognition with the restored images was much enhanced. Experimental results showed that when the iris images down-sampled by 6% compared to the original image were restored into the high resolution ones by using the proposed method, the EER of iris recognition was reduced as much as 0.133% (1.485% - 1.352%) in comparison with that by using bi-linear interpolation

하이브리드 SEM 시스템

  • Kim, Yong-Ju
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.109-110
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    • 2014
  • 주사전자현미경(Scanning Electron Microscopy: SEM)은 고체상태에서 미세조직과 형상을 관찰하는 데에 가장 다양하게 쓰이는 분석기기로서 최근에 판매되고 있는 고분해능 SEM은 수 나노미터의 분해능을 가지고 있다. 그리고 SEM의 초점심도가 크기 때문에 3차원적인 영상의 관찰이 용이해서 곡면 혹은 울퉁불퉁한 표면의 영상을 육안으로 관찰하는 것처럼 보여준다. 활용도도 매우 다양해서 금속파면, 광물과 화석, 반도체 소자와 회로망의 품질검사, 고분자 및 유기물, 생체시료 nnnnnnnnn와 유가공 제품 등 모든 산업영역에 걸쳐 있다(Fig. 1). 입사된 전자빔이 시료의 원자와 탄성, 비탄성 충돌을 할 때 2차 전자(secondary electron)외에 후방산란전자(back scattered electron), X선, 음극형광 등이 발생하게 되는 이것을 통하여 topography (시료의 표면 형상), morphology(시료의 구성입자의 형상), composition(시료의 구성원소), crystallography (시료의 원자배열상태)등의 정보를 얻을 수 있다. SEM은 2차 전자를 이용하여 시료의 표면형상을 측정하고 그 외에는 SEM을 플랫폼으로 하여 EDS (Energy Dispersive X-ray Spectroscopy), WDS (Wave Dispersive X-ray Spectroscope), EPMA (Electron Probe X-ray Micro Analyzer), FIB (Focus Ion Beam), EBIC (Electron Beam Induced Current), EBSD (Electron Backscatter Diffraction), PBMS (Particle Beam Mass Spectrometer) 등의 많은 분석장치들이 SEM에 부가적으로 장착되어 다양한 시료의 측정이 이루어진다. 이 중 결정구조, 조성분석을 쉽고 효과적으로 할 수 있게 하는 X선 분석장치인 EDS를 SEM에 일체화시킨 장비와 EDS 및 PBMS를 SEM에 장착하여 반도체 공정 중 발생하는 나노입자의 형상, 성분, 크기분포를 측정하는 PCDS(Particle Characteristic Diagnosis System)에 대해 소개하고자 한다. - EDS와 통합된 SEM 시스템 기본적으로 SEM과 EDS는 상호보완적인 기능을 통하여 매우 밀접하게 사용되고 있으나 제조사와 기술적 근간의 차이로 인해 전혀 다른 방식으로 운영되고 있다. 일반적으로 SEM과 EDS는 별개의 시스템으로 스캔회로와 이미지 프로세싱 회로가 개별적으로 구현되어 있지만 로렌츠힘에 의해 발생하는 전자빔의 왜곡을 보정을 위해 EDS 시스템은 SEM 시스템과 연동되어 운영될 수 밖에 없다. 따라서, 각각의 시스템에서는 필요하지만 전체 시스템에서 보면 중복된 기능을 가지는 전자회로들이 존재하게 되고 이로 인해 SEM과 EDS에서 보는 시료의 이미지의 차이로 인한 측정오차가 발생한다(Fig. 2). EDS와 통합된 SEM 시스템은 중복된 기능인 스캔을 담당하는 scanning generation circuit과 이미지 프로세싱을 담당하는 FPGA circuit 및 응용프로그램을 SEM의 회로와 프로그램을 사용하게 함으로 SEM과 EDS가 보는 시료의 이미지가 정확히 일치함으로 이미지 캘리브레이션이 필요없고 측정오차가 제거된 EDS 측정이 가능하다. - PCDS 공정 중 발생하는 입자는 반도체 생산 수율에 가장 큰 영향을 끼치는 원인으로 파악되고 있으며, 생산수율을 저하시키는 원인 중 70% 가량이 이와 관련된 것으로 알려져 있다. 현재 반도체 공정 중이나 반도체 공정 장비에서 발생하는 입자는 제어가 되고 있지 않은 실정이며 대부분의 반도체 공정은 저압환경에서 이루어지기에 이 때 발생하는 입자를 제어하기 위해서는 저압환경에서 측정할 수 있는 측정시스템이 필요하다. 최근 국내에서는 CVD (Chemical Vapor Deposition) 시스템 내 파이프내벽에서의 오염입자 침착은 심각한 문제점으로 인식되고 있다(Fig. 3). PCDS (Particle Characteristic Diagnosis System)는 오염입자의 형상을 측정할 수 있는 SEM, 오염입자의 성분을 측정할 수 있는 EDS, 저압환경에서 기체에 포함된 입자를 빔 형태로 집속, 가속, 포화상태에 이르게 대전시켜 오염입자의 크기분포를 측정할 수 있는 PBMS가 일체화 되어 반도체 공정 중 발생하는 나노입자 대해 실시간으로 대처와 조치가 가능하게 한다.

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Behaviour of Nanoemulsions Containing Ceramide IIIB and Stratum Corneum Lipids (세라마이드 IIIB와 각질층 지질을 함유한 나노에멀젼의 거동)

  • Cho, Wan Goo;Kim, Kyung Ah;Jang, Seon Il;Cho, Byoung Ok
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.44 no.1
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    • pp.31-37
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    • 2018
  • Oil/water (O/W) nanoemulsions are effective vehicles to change the permeability of the skin. In this study, we focused on the preparation and characterization of nanoemulsion which serve as colloidal carriers for the dermal application of ceramide IIIB (CIIIB) and stratum corneum (SC) lipids such as cholesterol, and palmitic acid. In order to optimize the nanoemulsions, emulsification process conditions were conducted with regard to droplet size, nanoemulsion stability, and solubility of CIIIB. A decrease in droplet size was observed through emulsification temperature of $80^{\circ}C$ and phase inversion composition (PIC) method. CIIIB has low solubility in oil and water. When the concentration of CIIIB was increased, the droplet size of nanoemulsion was increased. When Lipoid S75-3 was added to the oil phase, the solubility of CIIIB increased, indicating some interactions shown in DSC measurements. CIIIB and SC lipids could be successfully incorporated in nanoemulsions without crystallization or physical instability. In conclusion, a stable nanoemulsion containing the SC lipids could be effective as an efficient moisturizing system for skin.