• Title/Summary/Keyword: 체내 흡수도

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Study on the Radiation Dose about Skin Thickness of Rat (For Radiation Damage Tissue Engineering) (쥐의 피부두께에 따른 선량연구)

  • Jung, Hongmoon;Won, Doyeon;Kim, Hyeongyun;Jung, Jaeeun;Choi, hyeun-woo
    • Journal of the Korean Society of Radiology
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    • v.10 no.6
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    • pp.375-379
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    • 2016
  • A rat is the most common experimental animal used for the realization of the radiation injury model. The certain thickness of rat skin was prepared by peeling off a rat skin. Radiation level was measured by using this rat skin. Also, The schematic of the formula was made that can predict the radiation absorbed dose (RAD) as a function of the thickness of the rat skin. Consequently, we will provide the RAD information in the realization of in-vitro experimental model regarding the rat's skin thickness by applying the formulas. Moreover, the results from this study can be effectively used for the in-vitro experiment of the rat subcutaneous tissue which was exposed to radiation.

The dyeability of the heat resistant and biodegradable polyester with the variation of dyeing temperature (염색온도에 따른 고내열 생분해성 폴리에스테르계 섬유의 염색성)

  • Kim, Moon-Joung;Kim, Jong-Hoon;Park, Sung-Yoon
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2011.03a
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    • pp.85-85
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    • 2011
  • 화학적 혹은 생물학적인 방법으로 합성된 생분해성 고분자(biodegradable polymers)는 환경 문제와 인간의 생명 유지와 같은 인간 생활과 밀접한 관계가 있는 적용 분야로 인해 많은 관심을 받고 있으며, 국내 플라스틱의 폐기량만 해도 2003년을 기준으로 연간 4,000톤을 쉽게 넘고 있고 재활용되는 양은 전체의 1/3 수준이며, 나머지 2/3는 소각되거나 매립되고 있다. 폴리에스테르계 생분해성 섬유는 "미생물이 분비하는 효소로, 분해 가능한 화학합성 섬유"로서, 미생물이 분비하는 가수분해 효소에 의해 고분자 쇄가 절단, 저분자량 화합물이 돼 미생물의 체내로 흡수되며, 이것이 미생물의 체내에서 효소작용에 의해 산화탄소와 물로 분해되는 섬유로 정의된다. 생분해성 고분자 중 화학합성 고분자인 지방족 폴리에스테르계 생분해성 고분자는 특히 환경 산업으로부터 많은 관심을 받고 있으며, 이러한 결정성 폴리에스테르계 고분자의 물성은 고분자의 결정화도 뿐만 아니라, 압력, 온도 등에 의해서 변할 수 있는 결정 구조에 의해 크게 영향을 받는다. 생분해성 섬유는 실용화가 이미 시작됐고, 다용도화와 수요 확대를 위해 많은 연구소와 대학, 기업들이 연구개발을 진행하고 있으며, 향후 석유자원이 고갈된다는 것은 명백한 사실이므로 이에 따라 화석자원의 절약과 유효 이용을 위해서라도 바이오 베이스 폴리머를 주원료로 한생분해성 섬유의 개발은 매우 중요한 의미를 갖는다. 본 연구에서는 합성섬유 중에서 75%의 비중을 차지하는 폴리에스테르를 대체 가능한 고내열생분해성 폴리에스테르계 직물을 제조하여 범용 폴리에스테르와 염색온도에 대한 염색성을 고찰하였다. 염색온도($100^{\circ}C$, $110^{\circ}C$, $120^{\circ}C$, $130^{\circ}C$)별, 3종의 분산염료의 농도(0.25,0.5,1.0,2.0%o.w.f)별 Build-up성 및 균염성을 비교하였으며, 염색 시료의 견뢰도를 평가하였다.

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In Vivo Metabolic studies on Carbofuran Degradation in carp(Cyprinus carpio L.) (Carbofuran 의 잉어(Cyprinus carpio)체내 대사)

  • Lee, Yang-Kee;Kim, In-Seon;Im, Keon-Jae;Suh, Yong-Tack
    • Korean Journal of Environmental Agriculture
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    • v.16 no.1
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    • pp.25-30
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    • 1997
  • Absorption, distribution, metabolism and excretion of $^{14}C-carbofuran$(2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamte) were studied in carp(Cyprinus carpio L.) after the treatment of carbofuran at the dose level of 43 parts per billion. Maximum radioactivities in tissues(liver, kidney, gut, gall bladder) and blood of carp were shown 12hrs after the treatment of $^{14}C-carbofuran$. Carbofuran was metabolized to 3-hydroxycarbofuran and 3-ketocarbofuran in liver and kindney of carp, and the major metabolite was 3-hydroxycarbofuran. Most radioactivity absorbed into the carp tissues was eliminated 3hrs after transfer of the carp to fresh water. The excretory metabolites were 3-ketocarbofuran(32.3%), 3-hydroxycarbofuran(52.8%) and an unknown metabolite(2.6%) during the period of 3hrs of the excretory experiment.

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Changes of Physiological Properties of Zelkova serrata to NaCl Concentration in Soil (토양 중 NaCl 농도에 따른 느티나무의 생리적 특성 변화)

  • 송근준;한심희;하태주
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.5 no.3
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    • pp.166-171
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    • 2003
  • This study was conducted to investigate the negative physiological impact of saline to roadside trees and to assess the physio-biochemical tolerant characters of woody plants against salinity. Two-year-old Zelkova serrata seedlings treated with 0, 3, 14, 56, and 112 mM NaCl were measured for root collar diameter and cambial electric resistance (as an indication of vitality) and analyzed for carbohydrate and mineral content in the leaves. Z. serrata was affected by NaCl treatments. The vitality of Z. serrata decreased with an increase in NaCl concentration, and the NaCl treatment resulted in nutrient imbalance shown by changes of ion concentration in the tissues. However, relative growth rate for diameter and carbohydrate metabolism in the leaves were not greatly influenced by NaCl treatment. Short-term treatment or low NaCl concentration may not have an observed impact on growth. Nevertheless, roadside trees exposed to saline during the long term would likely show negative effects for growth performance from altered ion concentrations.

Determination of Proton Beam Position Based on Prompt Gamma Ray Detection (즉발감마선을 이용한 양성자 빔 위치 측정에 관한 연구)

  • Seo, Kyu-Seok;Kim, Jong-Won;Kim, Chan-Hyeong
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2004.11a
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    • pp.69-71
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    • 2004
  • The proton therapy of radiation therapy methods using Bragg Peak which is proton beam's characteristic dose distribution can give a normal tissue lower dose than cancer, comparing with the former existing radiation therapy methods. For exact treatment and patient' safety, we need to know proton beam's position in body, but a proton beam completely stops at treatment region and proton beam's range is uncertainly made by the variety of organs having each different density, so we aren't able to find a proton beam' position by suitable methods yet. With Monte Carlo Computing Method, as a result that we had simulated prompt gamma detection system using correlation of proton beam's absorbed dose distribution about water and prompt gamma distribution by nuclear interaction occurred by collisions of proton and water's hydrogen atoms, we could confirm that a proton beam's position was able to detect by using simulated prompt gamma detection system in body on the real-time

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Calcium Absorption Accelerating Effect of Chitosnn Oligosaccharides prepared by Ultrafiltration Membrane Enzymatic Reactor (한외여과막 효소반응기를 이용하여 제조한 키토산 올리고당의 칼슘흡수 촉진효과)

  • JEON You-Jin;KIM Gyu-Hyung;PARK Pyo-Jam;KIM Se-Kwon
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.3
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    • pp.247-251
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    • 1999
  • In spite of various bio-functionalities of chitosan, the effects in vivo were still ambiguous because of its low absorption on organism. Therefore, chitosan oligosaccharides (COSs) are necessary to elucidate for an efficient utilization in vivo. COSs were prepared from chitosan using ultrafiltration membrane enzymatic reactor system with MWCO (molecular weight cut-off) 3,000 Da of membrane. Calcium absorption accelerating effect using COSs was examined by two methods, in vitro and in vivo. In vitro experiment, calcium absorption by the addition of COSs in a mixture solution of calcium and phosphate was higher approximately $50\%$ than that by control. In vivo using rats, group taken the diet contained $1\%$ COSs anil calcium chloride decreased about $75\%$ of calcium content excreted from feces, and then, showed about $15\%$ increase in breaking force of femur. These results demonstrated that COSs definitely involved in calcium metabolism in vivo.

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Absorption of sulfur dioxide gas with various crops and it's relation to leaf injury (아황산가스에 의(依)한 작물별파해엽율(作物別破害葉率) 및 가스흡수량조사(吸收量調査))

  • Kim, B.Y.;Han, K.H.
    • Korean Journal of Soil Science and Fertilizer
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    • v.13 no.1
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    • pp.39-44
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    • 1980
  • To study the effects of sulfur dioxide on the plant; Barly, wheat, soybean sweet potato, cucumber, egg plant, red pepper, tomato, lettuce, water melon, castor bean, grape and lily were exposed to the different levels of sulfur dioxide gas(0.1, 0.25, 0.50, $1.0mg/{\ell}/hr$) The symptoms of damage, ratios of destroyed leaf, sulfur content and absorption amounts of the gas by leaves were investigated 1. According to the increasing concentration of the gas ratios of destroyed leaf were increased in all plants. The ratios of destroyed leaf were shown by egg plant at $0.1mg/{\ell}/hr$ of $SO_2$ were 30 percent, and no visible injuries were shown by the wheat potato, castor bean, water melon, lily at $0.25mg/{\ell}/hr$. 2. Gray and red brown spots between the vein nerve shown by barly and wheat leaf; leaf burn by soybean, potato, sweat potato, castor bean, egg plant, red pepper, tomato and grape; leaf withering from the leaf tips by the lettuce, water melon, lily. 3. The volums of the gas absorption by cucumber, egg plant, red peper, castor he an were more than $10{\ell}/hr$, however less than $2{\ell}/hr$, be lettuce, water melon, grape, barly and wheat. 4. According to the increasing concentration of sulfur dioxide gas, sulfur contents in leaf were increased in all plants, however volums of absorption gas were decreaed. 5. According to the increase of sulfur content in leaf, ratios of destroyed leaf were increased. 6. Positive correlation was shown between total and water soluble sulfur content in leaf.

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Influence of Water Temperature on the Changes of Soil and Plant Nutrient of Paddy Rice (관개수온(灌漑水溫)의 차이(差異)가 토양(土壤) 및 수도체내(水稻體內) 양분변동(養分變動)에 미치는 영향(影響))

  • Kim, L.Y.;Min, K.B.;Jo, I.S.;Ju, N.S.;Um, K.T.
    • Korean Journal of Soil Science and Fertilizer
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    • v.18 no.3
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    • pp.247-253
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    • 1985
  • In order to investigate the effects of water temperature on chemical properties of soil and nutrient uptake of rice plant, four varieties of rice were cultivated in a field where water temperature range was $17.3-23.0^{\circ}C$ and plant samples were taken at three growing stages and were analyzed in detail. The results were summarized as follows: 1. Organic matter content and pH of surface soil were showed no differences while the contents of $P_2O_5$ and $SiO_2$ were increased and potassium was decreased as the water temperature increased. 2. The amounts of nutrient uptake were related to the water temperature and the total nutrient contents of rice plants at harvesting stage were in order of $SiO_2$ > $K_2O$ > T-N > $P_2O_5$ > MgO. The rate of $SiO_2$/N and $K_2O$/N of rice plants grown at water temperature $23.0^{\circ}C$ were over two times to those of the water temperature $17.3^{\circ}C$. 3. Nutrient contents of rice plants showed a increasing tendency as increasing the water temperature. However, nutrient contents such as T-N at whole period, $P_2O_5$ at heading and harvesting stage, and $K_2O$ at heading stage were higher at low water temperature than those of high water temperature. 4. Most of nitrogen was translocated and accumulated in grain, potassium in straw respectively. All nutrients translocated to grain more easily as the water temperature increased.

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Effects of Supplemental Agents Enhancing Calcium Absorption on Bioavailability of Starfish Calcium in Rats (흰쥐에서 불가사리칼슘의 체내이용성에 대한 칼슘흡수증진물질의 첨가 효과)

  • Moon, Ji-Young;Jang, Soo-Jung;Park, Mi-Na;Park, Hee-Yeon;Lee, Yeon-Sook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.7
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    • pp.832-839
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    • 2007
  • This study was conducted to investigate the bioavailability of starfish calcium with substances enhancing calcium absorption. Three week-old young female rats (Sprague-Barley) were divided into 5 groups according to calcium sources and testing agents; calcium carbonate (C), starfish calcium (S), starfish calcium + casein phosphopeptide (S-CPP), starfish calcium+citrate-malate (S-CM), starfish calcium+isoflavone (S-ISO), and were fed experimental diets containing AIN-93G based Ca (0.35% w/w) diet with CPP, CM and ISO for 6 weeks. Blood, femur, urine and feces samples were collected. There was no significant difference among groups in terms of growth and food intake. Serum Ca concentrations were normal in all 5 groups. Serum P concentrations and ALP activities were not significantly different among groups. Ca absorption and retention were significantly increased both in S-CPP and S-CM groups compared to C group (p<0.05). p absorption was significantly higher in S-CPP group than in other groups. While the amount of soluble Ca of intestinal contents did not differ among groups, the amount of insoluble Ca was significantly lower in S-CPP, S-CM and S-ISO groups than in C and S groups. However, the weight, Ca and P concentrations of femur were not significantly different among groups. These results suggest that the addition of CPP and citrate-malate were more effective for enhancing the bioavailability, intestinal absorption and solubility of starfish calcium.

WATER CHLOROFORM LEVELS IN INDOOR SWIMMING POOLS IN A CITY OF KOREA AND IN A CITY OF NEW JERSEY IN THE UNITED STATES (국내 및 미국 뉴저지주의 수영장 물에서의 클로로포름)

  • 조완근
    • Journal of Environmental Science International
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    • v.3 no.2
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    • pp.101-109
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    • 1994
  • Chlorinated water in swimming pools contains chloroform at elevated levels compared to chlorinated drinking water Chloroform levels in four indoor swimming pools(swimming pools A, B and C in a city of Korea and swimming pool D in a city of New Jersey in the United States) were examined. The chloroform levels in the water of swimming pool C (city-managed) weve shown to be significantly(p=0.0001) different from those of private swimming pools A and B: the mean chloroform levels in the pools A, B, and C are 22.8, 17.8, and 31.1 $\mu\textrm{g}$/l, respectively. Furthermore, all of these chloroform levels are significantly(P=0.0001) different from those of New Jersey: chloroform concentration of the Korean pools ranged from 10.9 $\mu\textrm{g}$.l to 47.9 $\mu\textrm{g}$/l with a mean of 23.2 $\mu\textrm{g}$/l, while it ranged from 27 $\mu\textrm{g}$/l to 96$\mu\textrm{g}$/l with a mean of 64.4 $\mu\textrm{g}$/l in the New Jersey pool. The disinfection processes would cause part of this difference since the swimming pools in Korea applied both chlorination and ozonation method, while the swimming pool in New Jersey used chlorination method only. It was implied that swimming parameters inconsistently vary, resulting in fluctuation of and no constant accumulation of chloroform in the water with the change of time for the day. A regression analysis showed no relationships between sampling time and chloroform concentrations for the sampling day in the swimming pools of Korea. A F-test indicated no significant difference of chloroform concentrations in the morning and afternoon samples collected in the swimming pools. Ingestion dose was estimated to be 0.58$\mu\textrm{g}$ from an hour swimming in a city of Korea, taking into accounting an average of 23.2 $\mu\textrm{g}$/l in swimming pools in the city In extreme situation, the ingestion dose was estimated to be 12.0 $\mu\textrm{g}$ from an hour swimming in a city of Korea.

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