• Title/Summary/Keyword: 청성뇌간반응

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Development of a Portable Automatic Auditory Response Tester for Hearing Loss Screening (난청감별을 위한 휴대용 자동 청성반응 검사기의 개발)

  • Kim, Soo-Chan
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.49 no.2
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    • pp.38-45
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    • 2012
  • If an infant with congenital hearing loss is diagnosed in good time and get proper treatment as soon as possible, treatment effect could be maximized and the social costs could be considerably reduced. For these reasons, the medical equipment to screen hearing impairment objectively is needed. The ABR(auditory brainstem response) is typical diagnostic tools for this purpose but there are drawbacks in sense that it does not have frequency specificity and shows hearing information of usually high frequency band. The ASSR(auditory steady-state response) is excellent in frequency specificity, but the rate of wrong diagnosis is slightly high. In this study, we proposed the system which can measure both the ABR and the ASSR, and can show the objective and quantitative indices(Fsp and F-test). It was designed to allow various tests without hardware modification by minimizing hardware components and by increasing software roles. The objective assessment of the developed system was evaluated by experiments with 10 normal persons.

Correlation of acoustic features and electrophysiological outcomes of stimuli at the level of auditory brainstem (자극음의 음향적 특성과 청각 뇌간에서의 전기생리학적 반응의 상관성)

  • Chun, Hyungi;Han, Woojae
    • The Journal of the Acoustical Society of Korea
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    • v.35 no.1
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    • pp.63-73
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    • 2016
  • It is widely acknowledged that the human auditory system is organized tonotopically and people generally listen to sounds as a function of frequency distribution through the auditory system. However, it is still unclear how acoustic features of speech sounds are indicated to the human brain in terms of speech perception. Thus, the purpose of this study is to investigate whether two sounds with similar high-frequency characteristics in the acoustic analysis show similar results at the level of auditory brainstem. Thirty three young adults with normal hearing participated in the study. As stimuli, two Korean monosyllables (i.e., /ja/ and /cha/) and four frequencies of toneburst (i.e., 500, 1000, 2000, and 4000 Hz) were used to elicit the auditory brainstem response (ABR). Measures of monosyllable and toneburst were highly replicable and the wave V of waveform was detectable in all subjects. In the results of Pearson correlation analysis, the /ja/ syllable had a high correlation with 4000 Hz of toneburst which means that its acoustic characteristics (i.e., 3671~5384 Hz) showed the same results in the brainstem. However, the /cha/ syllable had a high correlation with 1000 and 2000 Hz of toneburst although it has acoustical distribution of 3362~5412 Hz. We concluded that there was disagreement between acoustic features and physiology outcomes at the auditory brainstem level. This finding suggests that an acoustical-perceptual mapping study is needed to scrutinize human speech perception.

Clinical Significance of Auditory Brainstem Response(ABR) in Speech/Language Disorders (언어발달장애에 있어서 청성뇌간반응의 임상적 의의)

  • Oh, Ki Won;Park, Woo Saeng;Kwon, Soon Hak;Kim, Jin Kyung;Lee, Jun Hwa
    • Clinical and Experimental Pediatrics
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    • v.45 no.10
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    • pp.1199-1203
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    • 2002
  • Purpose : The study aimed to evaluate the efficacy of auditory brainstem response(ABR) as a screening tool in children with speech and language disorders. Methods : Between January 1, 1999 and December 31, 2001, 139 patients with chief complaints of speech and language delay were recruited from the pediatric neurology clinic, Kyungpook National University Hospital, Daegu, Korea. They had ABR on entry and the clinical data were then analyzed. Results : Fifteen out of 139 cases(10.8%) showed abnormal findings; seven had pervasive developmental disorders, four had developmental language disorders, and four were noted to have other conditions. Among them, seven cases were noted to have conductive hearing loss and eight had sensoryneuronal hearing loss. We also evaluated the normal values in children at the ages of 18 months to seven years. The mean latency of wave I and V were $1.40{\pm}0.13$ and $5.57{\pm}0.26$ respectively. Interpeak latency of I-V was $4.18{\pm}0.24$. Conclusion : Based on these findings, ABR has proved to be a highly sensitive and specific index of hearing impairment. It should be used as a screening tool in children with speech and language disorders.

Automated algorithm of automated auditory brainstem response for neonates (신생아 청성뇌간 반응의 자동 판독 알고리즘)

  • Jung, Won-Hyuk;Hong, Hyun-Ki;Nam, Ki-Chang;Cha, Eun-Jong;Kim, Deok-Won
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.44 no.1
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    • pp.100-107
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    • 2007
  • AABR(automated auditory brainstem response) test is used for the screening purpose of hearing ability of neonates. In this paper, algorithm using Rolle's theorem is suggested for automatic detection of the ensemble averaged ABR waveform. The ABR waveforms were recorded from 55 normal-hearing ears of neonates at screening levels varying from 30 to 60 dBnHL. Recorded signals were analyzed by expert audiologist and by the proposed algorithm. The results showed that the proposed algorithm correctly identified latencies of the major ABR waves (III, V) with latent difference below 0.2 ms. No significant differences were found between the two methods. We also analyzed the ABR signals using derivative algorithm and compared the results with proposed algorithm. The number of detected candidate waves using the proposed algorithm was 47 % less than that of the existing one. The proposed method had lower relative errors (0.01 % error at 60dBnHL) compared to the existing one. By using proposed algorithm, clinicians can detect and label waves III and V more objectively and quantitatively than the manual detection method.

THE EFFECT OF SEDATIVES ON AUDITORY BRAINSTEM RESPONSE (Sedative가 정상청력 성인의 ABR에 미치는 영향)

  • 손진호;장원삼;손수준;조태환;성창섭
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1987.05a
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    • pp.7.3-8
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    • 1987
  • 청성뇌간 유발반응이 Juwett 및 Sohmer와 Feinmesser에 의하여 보고된 이래 타각적 청력검사로서 임상적응용에까지 이르렀다. 타각적 청력검사는 반응역치와 청각역치의 오차가 적어야 하며 주파수별로 역치측정이 가능하여야 하며 개인차가 적고 반응의 재현성이 높아야 되며 반응의 판정이 용이해야 함이 필요조건으로서 이러한 조건이 피검자의 수면상태하에서도 충족되어야 한다. 저자들은 정상 성인 청력자를 대상으로 sedation전후의 ABR에 대한 latency 및 amplitude를 중심으로 관찰하여 다음과 같은 결과를 얻었다. 1) Sedative의 사용에 있어서 amplitude및 latency의 차이는 없었다. 2) Sedative의 사용에는 무관하게 low frequency filter에서 high frequency filter보다 voltage의 유의한 차가 있었다.

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Binaural Interaction Component in Auditory Brainstem Responses with Asymmetric Simultaneous Acoustic Stimulation (비대칭 음 강도 양이 동시 자극 청성뇌간유발반응의 양이간섭치)

  • Heo, S.D.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.8 no.2
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    • pp.95-99
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    • 2014
  • Binaural interaction can recognize the same intensity sound by stimulating two ears alternatively, and it can be record auditory brainstem responses (ABR). However, We needs to be researched about binaural interaction in asymmetric binaural acoustic stimulation. 17 normal young hearing university students were participated. Clicks were presented at the intensity of 90 dB nHL to one ear and the click intensity was increased from 0 to 90 dB nHL with a separation of 10 dB to another ear, simultaneous. BI waveform was obtained by subtracting the sum of the asymmetrically evoked potentials from the binaurally evoked potentials; i.e. BI = B - (L + R). Latency and amplitude was measured 'peak to following trough' of IV-V complex of BI waveform. Threshold of BIC (t-BIC) was obtained using amplitude depend on stimulus intensities (paired sample t-test). Latency shifted in 4.65, 4.63, 4.57, 4.58, 4.62, 4.6, 4.48, 4.36, 4.23 ms for peak, 5.57, 5.51, 5.51, 5.59, 5.61, 5.55, 5.44, 5.28, 5.19 ms for trough, and amplitude shifted in .0.32, -0.3, -0.34, -0.32, -0.42, -0.53, -0.54, -0.61, $-0.67{\mu}V$ from 0 to 90 dB nHL in every 10 dB, respectively. t-BIC was observed 40 dB nHL(p=.001).

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Development of A-ABR system for identifying difficulty in hearing (난청 감별을 위한 자동청성뇌간반응검사(A-ABR) 측정기 개발)

  • No, Hyung-Wook;Kim, Soo-Chan;Cha, Eun-Jong;Kim, Deok-Won
    • Proceedings of the KIEE Conference
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    • 2008.04a
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    • pp.141-142
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    • 2008
  • Hearing loss is the most common birth defect among infants. Yet most hearing-impaired children are not identified until 1 to 3 years of age - which is well beyond the critical period(6 month) for healthy speech and language development. However, if a hearing-impairment is identified and treated in its early stages, child's speech and language skills will be comparable to his or her normal- hearing peers. For these reasons, hearing screening at birth and routinely throughout childhood is extremely important. Auditory brain-stem response(ABR) is nowadays one of the most reliable diagnostic tools in the early detection of hard of hearing. In this study, we developed the system that detects auditory evoked potential using micro-processor. Furthermore, it is required to develop a portable system to measure in not only soundproof room but also nursery for infants.

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Development of A-ABR system using microprocessor (마이크로프로세서를 이용한 자동청력검사(A-ABR) 시스템 개발)

  • Noh, Hyung-Wook;Kim, Soo-Chan;Ji, Hyu-Chul;Cha, Eun-Jong;Kim, Deok-Won
    • Proceedings of the KIEE Conference
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    • 2008.10b
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    • pp.201-202
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    • 2008
  • 난청은 가장 흔한 선천성 장애이다. 이 질병의 발생 빈도는 신생아 1000명 출생 당 $1{\sim}3$명 정도로 상당히 높다. 이러한 청력 장애가 조기에 발견된다면 수술적인 치료 등으로 예방할 수 있으나 그렇지 못할 경우 언어와 학습장애를 초래하게 된다. 이런 관점을 근거로 신생아를 대상으로 한 선천성 난청의 선별검사는 큰 의미를 가지며 난청환자의 조기발견을 위한 노력이 필수적이라 할 수 있다. 기존의 수동 청력검사 시스템은 신생아 청력 평가시 검사자의 주관성에 의존하게 되므로, 청성뇌간 반응의 뇌파분석이 잘못될 가능성이 커진다. 따라서 본 연구에서는 청력 역치를 자동으로 판독하여 결과를 나오도록 개발하고자 하였으며, 또한 기존 제품들과는 차별화하여 휴대용으로 개발하여 차폐실이 아닌 일반 병실에서도 검사가 가능하도록 함에 따라 유소아의 청각 장애를 극복시키는데 기여하고자 하였다.

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Algorithm of an automated auditory brainstem response neonatal hearing screening method (신생아를 대상으로한 청성뇌간유발반응의 자동 판독 알고리즘)

  • Jung, Won-Hyuk;Hong, Hyun-Ki;Kim, Sung-Woo;Kim, Jin-Tae;Park, Joong-Hoon;Kim, Deok-Won
    • Proceedings of the IEEK Conference
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    • 2006.06a
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    • pp.825-826
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    • 2006
  • In this paper, we propose an algorithm that applies Rolle's theorem to automatically detect and label peak III and V of the normal, suprathreshold auditory brainstem response (ABR). ABR waveform were recorded from 55 normal-hearing ears at screening levels varying from 30 to 60 dBnHL. For each ABR waveform, the peak-finding algorithm proceeded in fourth steps: (1) Select maximum and minimum values of the target ABR waveform, (2) divide this range into n equal parts, (3) effective candidate peaks in the ABR waveform are identified using Rolle's theorem (4) peak III and V are identified from these candidate peaks based on their latency and morphology. As a result, proposed auto dectection method showed high correlation and accuracy with manual detection method performed by clinician. By using proposed algorithm, clinician can detect and label peak III and V faster and more efficient than manual detection method.

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Auditory brainstem response (ABR) results in NICU graduates (신생아 집중치료실 퇴원아의 청성뇌간반응(ABR) 결과에 미치는 위험인자 및 경과)

  • Choi, Hee-Joung;Lee, Tae-ho;Oh, Ki-Won;Kim, Heng-Mi
    • Clinical and Experimental Pediatrics
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    • v.49 no.12
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    • pp.1301-1307
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    • 2006
  • Purpose : Hearing loss is one of the most common birth defects, and early detection and intervention positively impact language/speech and cognitive development. It has been reported that NICU graduates have a high incidence of hearing loss. So we investigated the incidence, risk factors and clinical outcome of hearing loss in NICU graduates. Methods : This study involved neonatal auditory brainstem response (ABR) testing of newborn infants who graduated from the NICU of Kyungpook National University Hospital during a 3-year period (between July 2002 and June 2005) and subsequent follow-up of these infants. Results : ABR evaluations were performed on 474 infants. Of these infants, 64 showed abnormal ABR (13.5 percent). Of 128 ears from these 64 infants, two ears (1.6 percent) and 10 ears (7.8 percent) were classified as severe and profound hearing loss, respectively. The infants with abnormal ABR had higher incidence of prematurity, low birth weight, very low birth weight, neonatal asphyxia, cranio-facial malformation and amikacin treatment over 15 days (P<0.05). In infants with hyperbilirubinemia, the peak level of serum bilirubin, duration of phototherapy and exchange transfusion were not associated with the higher incidence of hearing loss. Follow-up ABR evaluation was performed on 15 infants with abnormal ABR at $8.8{\pm}4.4months$. In follow-up ABR, 80.0% showed improvement or normalization of threshold sensitivity. Conclusion : NICU graduates exhibit high risk for hearing loss. Systemic and effective hearing assessment program is needed for these high risk infants.