• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.3
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• pp.255-261
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• 2012

The skin is continuously exposed to environmental stresses. One of the most important stress factor is UV radiation. UV radiation causes a variety of biological effects on the skin, including inflammation, pigmentation, photoaging and cancer. Therefore in this study, we tried to search for skin-protective antioxidant materials from marine natural products (Porphyra Thalli, Laminariae japonicae thallus, Ostreae Concha, Sargassum Thallus, Undaria thallus, Haliotidis Concha, Agar, Codium thalli, Hizikia fusiforme thalli; HFE, Thalli) which exhibit protective activities against UVB-induced cytotoxicity and oxidative cell death and antiaging effects. As a results, UVB-induced cytotoxicity and cell death were effectively suppressed by treatment of Sargassum Thallus, Agar, Haliotidis Concha, Codium thalli, Thalli ethanol extracts. UVB-induced cell death was mediated by intracellular accumulation or ROS, which was significantly inhibited by treatment with marine natural products extracts. Also, The protective effect of these marine natural products seemed to be mediated by increased expression of type I collagen and Type I procollagen. These results suggest that marine natural products may have anti-aging effects new functional materials against oxidative stress-mediated skin damages.

• Journal of the Korea Society of Computer and Information
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• v.25 no.10
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• pp.261-268
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• 2020

In this paper, we propose an effective software education model for youths with disability. This software education model consists of a four-step process. In the first step, it draws the education curriculum of the software education for different types of disabled youths based on the results of comparative analysis of software education field in special education curriculum. In the second step, it suggests achievement standards for effective software education for the disabled students by classifying students with intellectual disabilities and visual, hearing, and physical disabilities without any multiple disabilities. In the third step, the study developed a modular textbook comprised of unplugged activities using coding robot Albert, physical computing, and block/text coding with the reflection of the characteristic of each type of disability. In the fourth step, it applied the textbook to the school field and educated disabled students focusing on experience to allow them to think logically and by stages about different problems they face in daily lives. In addition, by analyzing the results of youths' performance evaluation and surveys, it was shown that 82.3% of developmental disabilities, 78.8% of visual impairments, 90.9% of hearing impairments, and 78.8% of physically disabilities achieved achievements above the "medium" level. These results prove that the software education model for youths with disabilities proposed in this paper is very effective in improving computational chinking of youths with disabilities.

• Sleep Medicine and Psychophysiology
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• v.1 no.1
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• pp.87-98
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• 1994

Objectives: To examine a defect in inhibitory gating of auditory evoked response in schizophrenics, to compare P3 latency and amplitude in negative and positive schizophrenics, and to assess the association of P3 with family history of the psychiatric disorders, electroconvulsive therapy, and clinical features. Methods: 54 schizophrenics(male 31, female 23) and 75 controls(male 33, female 42) were tested with event-related potential paradigm designed to elicit P3 response and Frankfurter Beschwerde Fragebogen. Results: In schizophrenics, the latency of P3 was significantly more delayed and the amplitude of P3 was significantly more reduced than in the controls. Significant differences in P3 latency and amplitude between negative and positive schizophrenics were not found. And significant difference in the P3 latency and amplitude between schizophrenics with family histories of psychiatric disorder and those without family histories of psychiatric disorder was not found also. The P3 latency and amplitude was not significantly related with electroconvulsive therapy and other clinical features such as age, duration of illness, onset of inllness, number of admission, and doses of antipsychotics etc. Conclusion: These results suggested that schizophrenics had a dysfunction in the process of selective attention and that P3 was not significantly related with family history of the psychiatric disorders, positive and negative symptoms, electro1convulsive therapy, and clinical features in schizophrenics.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.20 no.1
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• pp.57-62
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• 2009

Background and Objectives : There are few studies reported that specifically examine the laryngeal function in patients with profound hearing loss or deafness, This study was designed to examine videostroboscopic findings and phonetic characteristics in adult patients with prelingually deaf. Materials and Method: Sixteen patients (seven males, nine females) diagnosed as prelingually deaf aged from 19 to 54 years, and were compared with a 20 normal control group with no laryngeal pathology and normal hearing group, Videostroboscopic evaluations were rated by experienced judges on various parameters describing the structure and function of the laryngeal mechanism during comfortable pitch and loudness phonations. Acoustic analysis test were done, and a nasalance test performed to measure rabbit, baby, and mother passage. CSL were measured to determine the first and two formant frequencies of vowels /a/, /i/, /u/, Statistical analysis was done using Mann-Whitney U or Wilcoxon signed ranks test. Results: Videostroboscopic findings showed phase symmetry but significantly more occurrences decrement in the amplitude of vibration, mucosal wave, irregularity of the vibration and increased glottal gap size during the closed phase of phonation, In addition, group of prelingually deaf patients were observed to have significantly more occurrences of abnormal supraglottic activities during phonation. The percentage of shimmer in the group of prelingually deaf patients were higher than in the control group. Characteristics of vowels were lower of the second formant of the vowel /i/. Nasalance in prelingually deaf patients showed normal nasality for all passages, Conclusion: Prelingually deaf patients show stroboscopic abnormal findings without any mucosal lesion, suggesting that they have considerable functional voice disorder. We suggest that prelingually deaf adults should perform vocal training for normalized laryngeal function after cochlear implantation.

• Science of Emotion and Sensibility
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• v.14 no.1
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• pp.59-72
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• 2011

Since stress can cause a variety of diseases, the relaxation of stress is an important factor for preventing diseases. One way to relieve stress is to use auditory or visual materials. If auditory and visual ones are used together, the effect of stress relaxation will be maximized. In this context, we analyze mood distribution of genre of music and color distribution of mood from the mood data for musics and color data for mood words collected directly from volunteers. Based on these two distributions, we also perform the $X^2$-test with Minitab for checking that color distributions are different from genre to genre. The results show that a different genre has a different color distribution and that the distributions of color, brightness and saturation depend on mood (P<0.0001). The results will be used to develop an emotional lighting system which plays lighting according to music mood, which can be applied to psychotherapy but more data and analysis are needed for clinical trials.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.32 no.4
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• pp.427-431
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• 1999

This study was conducted to investigate the inhibitory activity of water extracts and its enzymatic hydrolysates from algae against angiotensin-I converting enzyme (ACE). The 7 kinds of algae were extracted with water at $50^{\circ}C,\;70^{\circ}C$ and $98^{\circ}C$. ACE inhibitory activities of water extracts were the highest at $70^{\circ}C$, and those of ceylon moss, layer, green layer, sea mustard, seaweed fusiforme sea tangle and sea staghorn were $10.9\%,\;9.3\%,\;8.9\%,\;8.2\%,\;7.5\%,\;7.1\%$ and $7.0\%$, respectively. Layer, green laver sea mustard and ceylon moss of high ACE inhibitory activities among the 7 kinds of water extracts were hydrolyzed by maxazyme and papain during 24hrs. ACE inhibitory activity of enzymatic hydrolysates was higher than that of water extracts, and was the highest in enzymatic hydrolysates of laver among the tested samples. In laver hydrolysates by proteases, the highest ACE inhibitory activity and peptide-nitrogen contents were observed at 8 hours hydrolysis and the hydrolysates by maxazyme showed relatively higher activity than those by papain(31.3 and $27.9\%$, respectively). But peptide-nitrogen contents were greater in papain hydrolysates than in maxazyme.

• Phonetics and Speech Sciences
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• v.13 no.4
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• pp.89-100
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• 2021

This study compared the voice range profiles (VRPs) with glissando and simplified VRP methods with 57 men who were in premutation (8-13 years), mutation (11-16 years), and postmutation (10-24 years) stages. The difference between modal and falsetto areas measured in two VRP methods was also compared. As the results, the average fundamental frequency (F0) was in the order of premuaton>mutation>postmutation. The maximum F0 (F0max), the range of F0 (F0range), the maximum intensity (Imax), and the range of intensity (Irange) were the lowest in the mutation stage, and these variables were higher in falsetto area than in modal area in both methods. In addition, most variables of VRP in glissando were higher than in simplified VRP, but the differences were not significant. This study showed that, in men in mutation stage, due to the temporary anatomical and physiological changes of the larynx, the mechanism of the vocal folds vibration changes and VRP shows a different pattern from that of other age groups. Both the VRPs of glissando and simplifed VRP are suitable for clinical practice by experienced examiners. And it is necessary to measure not only the falsetto area but also the modal area when measuring VRP.

• Phonetics and Speech Sciences
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• v.14 no.2
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• pp.77-86
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• 2022

This study aimed to investigate the voice onset time (VOT) of plosives in the VCV syllables by the place of articulation and phonation type spoken by children with bilateral cochlear implants (CIs) in comparison with children with typical hearing (TH). In all, 15 children with bilateral CIs and 15 children with TH participated in this study, aged between 5 to 10 years. All children produced 9 VCV syllables and their VOT were analyzed by the Praat software. There was no significant difference in mean VOT between children with bilateral CIs and children with TH. However, there was a significant difference in mean VOT by the place of articulation, such that the VOT for velars were longer than those for bilabials and alveolars. Additionally, there was a significant difference in mean VOT by the phonation type, such that the VOT of aspirated consonants were longer than those of lenis and fortis consonants. The results of this study suggest that children with bilateral CIs can distinguish the acoustic properties of plosive consonants and control the speech timing between the structures of the larynx and the oral cavity at a similar level as children with TH.

• Phonetics and Speech Sciences
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• v.14 no.4
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• pp.67-75
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• 2022

This study compared voice range profiles (VRPs) of modal and falsetto register in 53 dysphonic and 53 non-dysphonic adult women with gliding vowel /a/'. The results shows that maximum fundamental frequency (F0_MAX), maximum intensity (I_MAX), F0 range (F0_RANGE), and intensity range (I_RANGE) are lower in the dysphonic group than in the non-dysphonic group. F0_MAX and F0_RANGE are significantly higher in falsetto register than modal register in both groups. I_MAX and I_RANGE are significantly higher in falsetto register in the non-dysphonic group, but those are not different between two registers in the dysphonic group. There was no statistically significant difference in minimum F0 (F0_MIN) and minimum intensity (I_MIN) between the two groups. Modal-falsetto register transition occurred at 378.86 Hz (F4#) in the dysphonic group and 557.79 Hz (C5#) in the non-dysphonic group, which was significantly lower in the dysphonic group. It can be seen that both modal and falsetto registers in dysphonic adult women are reduced compared to non-dysphoinc adult women, indicating that the vocal folds of dysphonic adult women are not easy to vibrate in high pitches. The results of this study would be the basic data for understanding the acoustic features of voice disorders.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.7 no.4
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• pp.193-202
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• 2017

With the growth of Chinese manufacturing industry and strengthening of manufacturing industry in advanced countries, the competitiveness of Korean manufacturing industry has become weak. Accordingly, it is time when energy for new growth is required very strongly. This research is the basic research to construct a cognitive and emotional information system to support sound design in manufacturing industry, and aims to develop AUI (Auditory User Interface) guideline. To fulfill research aims, this research conducted interviews to persons belonging to the manufacturing industry, and analyzed contexts and major characteristics related with AUI design. In addition, this research conducted survey on 269 persons on user preference on representative function of products. By analyzing survey data, this research examined the most suitable melody method for each sound, and difference in user preference between men and women. Based on beep sound, it performed analysis focusing on the number of sounds, melody types, and code. It also extracted AUI guidelines usable when users of the product into male and female. This research has significance in the sense that it built the basic guide data which can support AUI design in manufacturing industry.