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Effect of prophylactic indomethacin in extremely low birth weight infants (초극소 저출생체중아에서 예방적 indomethacin 투여효과)

  • Lee, Bo Lyun;Kim, Su Jin;Koo, Soo Hyun;Jeon, Ga Won;Chang, Yun Sil;Park, Won Soon
    • Clinical and Experimental Pediatrics
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    • v.49 no.9
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    • pp.959-965
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    • 2006
  • Purpose : The purpose of this study was to investigate the effect of prophylactic indomethacin on reduction of patent ductus arteriosus(PDA) and intraventricular hemorrhage(IVH) in extremely low birth weight infants(ELBWI). Methods : Retrospective review of 84 ELBWI who were admitted to our neonatal intensive care unit from June 2004 to April 2006 was performed. Patients were divided into prophylactic group(n=28) and control group(n=56), where prophylactic indomethacin were given within 6 hours after birth. Clinical outcomes were compared between these groups. Results : There were no significant differences in gestational age, birth weight, incidence of hemodynamically significant PDA and severe IVH, and mortality between prophylactic group and control group. However, there were more frequent indications for therapeutic indomethacin, higher incidence of intestinal perforation, and longer time to achieve full enteral feeding in prophylactic group than control group. The incidence of other adverse events attributed to indomethacin prophylaxis did not differ between two groups. Conclusions : Prophylactic indomethacin may not prevent hemodynamically significant PDA and severe IVH in ELBWI. On the contrary, it may be associated with increased risk of adverse events. Further efforts should be investigated to decrease PDA and severe IVH in ELBWI.

Reconstruction after Wide Excision of Malignant Soft Tissue Tumor in Ankle and Foot (족관절 및 족부에 발생한 연부 조직 악성 종양의 광범위 절제술 후 재건술)

  • Kwon, Young-Ho;Cho, Yool;Kim, Jae-Do;Chung, So-Hak
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.1
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    • pp.33-43
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    • 2008
  • Purpose: To evaluate the clinical usability of reconstructive methods, and how to select flap after wide excision of malignant soft tissue tumor in ankle and foot. Materials and Methods: The 15 cases shown in the 14 patients (In case of a male patient, reconstruction was performed two times due to local recurrence.) with malignant soft tissue tumor in ankle and foot, who underwent reconstruction after wide excision from March 2000 until March 2007. Oncologic, surgical and functional results were evaluated. Results: The method of reconstruction used were anterolateral thigh perforator flap (5cases), Reversed superficial sural artery flap (4 cases), dorsalis pedis flap (3 cases), local flap (3cases). The defect, mean size was $5.5{\times}5.7\;cm$, was reconstructed with rotation flap or free flap, mean size was $5.9{\times}6.0\;cm$, skin graft for remnant. The mean operation time was 310 minutes (120~540 minutes); it took 256 minutes to reconstruct by rotation flap, and 420 minutes by free flap. As oncologic results, 7 patients were no evidence of disease, 6 patients were alive with disease and 1 patient was expired by pulmonary metastasis at the time of the last follow-up. 4 patients had local recurrence and 4 pateints had distant metastases. As functional results, 14 patients were evaluated with average score of 68.8% using the system of the Musculoskeletal Tumor Society. Conclusion: The dorsalis pedis and reverse superficial sural artery rotation flap which is easy procedure, has less complication and takes short operation time, can be primarily considered to reconstruct a small defect. And the anterolateral thigh perforator flap is suitable for coverage of a large defects after wide excision of malignant soft tissue tumor in ankle and foot.

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Effect of Non-Perforated Breathable Films on the Storability of 'Fuji' Apples in Modified Atmosphere Condition in the Different Storage Temperature (비천공 Breathable필름이 몇 가지 저장온도에서 '후지' 사과의 MA 저장성에 미치는 영향)

  • Choi, In-Lee;Sung Mi, Hong;Min Jae, Jeong;Jun Pill, Baek;Ho-Min, Kang
    • Journal of Bio-Environment Control
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    • v.23 no.1
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    • pp.60-64
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    • 2014
  • These studies were conducted to identify the effects of non-perforated breathable package film on storability at $1^{\circ}C$, $8^{\circ}C$, and $20^{\circ}C$ storage of 'Fuji' apples. The fresh weight loss rate was less than 2.0% in all non-perforated breathable films at three different storage periods and temperatures, $1^{\circ}C$; 210 days, $8^{\circ}C$; 75 days, and $20^{\circ}C$; 30 days except for the perforated film. 1,300 cc ($1^{\circ}C$), 5,000 cc ($8^{\circ}C$), and 10,000 cc ($20^{\circ}C$) films were closed at the optimum MA storage condition by carbon dioxide and oxygen concentration. Ethylene concentration was lowest at the 40,000 cc film in every temperatures during storage. The 1,300 cc film established higher result in soluble solid and vitamin C content than any other films at $1^{\circ}C$, also showed higher in visual quality by panel test. The 5,000 cc film had the best results on soluble solid and off-flavor in $8^{\circ}C$. In the $20^{\circ}C$ storage after 30 days of treatment the 10,000 cc film had highest firmness and visual quality. Following these results, it come to conclusion the suitable type of non-perforated breathable film such as 1,300 cc at $1^{\circ}C$, 5,000 cc at $8^{\circ}C$, and 10,000 cc at $20^{\circ}C$ for MA storage in 'Fuji' apples.

A Basic Study on Upward Soil Nailing Combined Horizontal Drainage (수평배수공을 겸한 상향식 쏘일네일링 공법의 기초연구)

  • Kim, Hongtaek;Lee, Jungjae;Chung, Jongmin;Choi, Geunhyeok;Lee, In
    • Journal of the Korean GEO-environmental Society
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    • v.10 no.7
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    • pp.151-158
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    • 2009
  • In the early 1990s, soil nailing was first introduced as method of reinforcement for the slope stability and ground excavation, and as its application was increased the improved soil nailing was also developed. Most recently used for grout soil nailing greatly improve the methods and techniques for self-improvement techniques are classified as soil nailing. As the representative for the grout pressure method to improve the join method pressure grouting and improved method for the self-drilled soil nailing, removable soil nailing, upward soil nailing combined with horizontal drainage system. This paper is to compare upward soil nailing combined with horizontal drainage system with downward direction of the soil nailing. In order to study the limit equilibrium slope stability analysis and comparison with factor of safage, excavation for the vertical displacement for comparison with continuous analysis. According to this study, safage factor is decreased considerably using limit equilibrium analysis and makes no odds for the horizontal displacement when soil nail was installed upward.

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Comparison of the Result of Radiation Alone and Chemoradiation in Cervical Cancer (자궁 경부암에서 방사선 단독치료와 방사선 및 화학요법 병행치료의 비교)

  • Kim, Jae-Cheol;Park, In-Kyu
    • Radiation Oncology Journal
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    • v.13 no.2
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    • pp.191-198
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    • 1995
  • Purpose: This analysis was to compare the result of radiation alone and chemoradiation in cervical cancer in terms of response, survival, failure, and complication. Materials and Methods: A retrospective analysis of 135 cervical cancer patients treated with definitive radiotherapy from November 1985 to December 1991 was performed. Fifty-six patients were treated with radiation alone and 79 patients were treated with cisplatin-based chemotherapy plus radiation. Follow-up period ranged from 5 to 105 months with a median 47 months. According to the FIGO classification, the patients were subdivided into 18 $(13.3\%)$ stage IB, 7 $(5.2\%)$ stage IIA, 97 $(71.9\%)$ stage IIB, and 9 $(6.7\%)$ stage IIIB. Results: A complete response was noted in 51 patients $(91.1\%)$ of the radiation alone group, and 68 patients $(86.1\%)$ of the chemoradiation group. There was no statistical difference in complete response rate between the two groups. Overall survival rate at 5 years was $73.3\%$. According to stage, overall survival rates at 5 years were $88.9\%$ in stage IB, $85.7\%$ in stage IIA, $73.8\%$ in stage IIB, and $37.5\%$ in stage IIIB, respectively. According to treatment modality, overall survival rates at 5 years were $81.9\%$ in the radiation alone group, $67.0\%$ in the chemoradiation group (p=0.22). Disease-free survival rate at 5 years were $70.4\%$ in the radiation alone group. $68.5\%$ in the chemoradiation group (p=0.85) Locoregional control rates at 5 years were $76.1\%$ in the radiation alone group, $73.8\%$ In the chemoradiation group (p=0.70). Distant disease-free survival rates at 5 years were $83.9\%$ in the radiation alone group, $90.3\%$ in the chemoradiation group (p=0.59). Treatment-related bone marrow suppressions were noted in 3 $(5.4\%)$ patients of the radiation alone group, 14 patients $(17.7\%)$ of the chemoradiation group (p(0.05). Grade 2 vesical complications were noted in 14 patients of the radiation alone group. and 10 Patients of the chemoradiation group. Grade 2 rectal complications were noted in 2 patients of the radiation alone group, and 3 Patients of the chemoradiation group. One case of rectal perforation was noted in the chemoradiation group, and grade 2 small bowel obstructions were noted in 2 patients of the radiation alone group. There were no statistical differences in the incidence of vesicar, rectal, and small bowel complicaions between the two groups. Conclusion: No statistical difference was found between the radiation alone group and the chemoradiation group in terms of response, survival, and failure. but the incidence of bone marrow suppression was higher in the chemoradiation group.

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Acute Suppurative Pericarditis Caused by Liver Abscess -1 case report- (간농양에 속발한 급성화농성 심 낭염 -1례 보고-)

  • 홍장수;노윤우
    • Journal of Chest Surgery
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    • v.29 no.7
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    • pp.785-788
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    • 1996
  • Pericardial abscess due to liver abscess is a very rare disease, the result of which is usually fatal when untreated. But a combination of antibiotics therapy and pericardial drainage has broug t good result. A 32-year-old man was admitted to the emergency room because of fever and chilling sensation. Chest X-ray showed cardiomegaly and a mass lesion In the left lobe of liver on ultrasonography. The echocardiography revealed impending cardiac tamponade. Pus drainage of the liver abscess through per- foration of right diaphram and pericardiotomy were performed. The pericardium was thickened and 600 ml of purulent fluid and necrotic debris were drained. Fibrin clots were firmly attached to the undelying myocradium. Histological examination of the pericardium showed acute inflammation with microabsscess and Escherichia soli was cultured from pericardial pus. He was discharged after 4 weeks on antibiotics, but Doppler echocardiograpy revealed a slightly thickened pericardium with a mild constrictive physiology.

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Statistical analysis of NTNU test results to predict rock TBM performance (TBM 굴진성능 예측을 위한 NTNU 시험결과의 분석)

  • Choi, Soon-Wook;Chang, Soo-Ho;Lee, Gyu-Phil;Bae, Gyu-Jin
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.13 no.3
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    • pp.243-260
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    • 2011
  • To predict TBM performance in design stage is indispensable for its successful application. The NTNU model, one of the representative TBM performance prediction models uses two distinct parameters such as DRI and CLI obtained from three different tests on bored rock cores. Based on DRI and CLI, it is possible to predict TBM advance rate and cutter life in the NTNU model. In this study, NTNU testing methods and their related testing equipments were introduced to measure DRl and CLI for the NTNU model. Then, in order to derive their relationships, the two key parameters measured for 39 domestic rocks were compared with physico-mechanical properties of rock such as uniaxial compressive strength and quartz content. Lastly, the experimental results were also compared with NTNU database to verify their reliability.

Analysis of Turbo Coding and Decoding Algorithm for DVB-RCS Next Generation (DVB-RCS Next Generation을 위한 터보 부복호화 방식 분석)

  • Kim, Min-Hyuk;Park, Tae-Doo;Lim, Byeong-Su;Lee, In-Ki;Oh, Deock-Gil;Jung, Ji-Won
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.9C
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    • pp.537-545
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    • 2011
  • This paper analyzed performance of three dimensional turbo code and turbo ${\Phi}$ codes proposed in the next generation DVB-RCS systems. In the view of turbo ${\Phi}$ codes, we proposed the optimal permutation and puncturing patterns for triple binary input data. We also proposed optimal post-encoder types and interleaving algorithm for three dimensional turbo codes. Based on optimal parameters, we simulated both turbo codes, and we confirmed that the performance of turbo ${\Phi}$ codes are better than that of three dimensional turbo codes. However, the complexity of turbo ${\Phi}$ is more complex than that of three dimensional turbo codes by 18%.

A Study on the Structural Stability of Prefabricated Strut for Ground Excavation Construction (지반굴착용 조립식 버팀보의 구조 안정성에 관한 연구)

  • Lee, Ki-Sun;Kim, Doo-Hwan;Song, Kwan-Kwon;Kim, Seong-Pil;Kim, Jeong-Hoon
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.22 no.3
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    • pp.75-83
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    • 2018
  • In study, Structural stability was considered when applying the high strength strut method with improved general strut method. considered whether there is sufficient stiffness to so as not buckling to the maximum hypothetical earth pressure. also structure stability of the strut component was reviewed. The high strength strut method is a technique used in place of the general strut method. high strength prefabricated Strut method is a technique that has bolt holes drilled in the upper flange at regular intervals. As a result of the buckling analysis, it was considered that the safety factor increased by about 5 %. also Since the stress generated is below the allowable stress, it is judged that structural stability of the strut is ensured. In particular, the safety factor of axial compressive stress increases about 16 % with use of high strength steel when applying the high strength prefabricated strut method. the high strength strut method is construction method may shorten the construction period and there is no expense to purchase additional materials.

부지화 감귤의 저장 품질특성에 미치는 중온처리 효과

  • 이현희;홍석인;손석민;김동만
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.10a
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    • pp.188.2-189
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    • 2003
  • 시설재배 만감류인 부지화 감귤의 수확후 저장유통시 부패 감소 및 상품성 제고를 위하여 환경친화적 전처리방법으로서 중온처리의 적용 가능성을 확인하고자, 제주 서귀포산 부지화(한라봉)감귤의 열수 및 열풍 처리에 따른 저장중 품질특성 변화를 살펴보았다. 표면상처가 없는 일정 크기의 건전 과실을 선별한 후, 각각 52$^{\circ}C$에서 2분(52-2m), 6$0^{\circ}C$에서 20초(60-20s) 동안 열수에 침지하거나 45$^{\circ}C$에서 4시간(45-4h), 8시간(45-8h) 동안 열풍을 가한 다음 5$^{\circ}C$에서 냉각 건조하였다. 충분히 냉각된 과실을 통기성 천공 LDPE 필름에 포장하여 5"C에서 21일, 18$^{\circ}C$에서 7일간 저장하면서 생리, 이화학, 관능적 특성을 측정하였다. 중온처리 직후 초기 호흡률은 처리구 모두 무처리구와 비교하여 다소 높았으나, 저장중 처리구 감귤의 호흡률은 감소하여 21일째는 무처리구와 동일한 수준을 나타내었다. 과실내 기체조성은 저장기간 및 처리구간에 차이를 보이지 않았으나 21일부터는 저장온도 전환에 따라 $CO_2$가 다소 증가하는 양상을 보였다. 과실의 pH, 산도, 경도는 중온처리에 따른 유의적 차이를 구분할 수 없었으나, 고형분 함량과 생체 중량감소율은 열풍처리구에서 다소 높게 유지되었다. 과피 표면색 역시 열풍처리구 (45-8h)가 다른 것에 비해 저장중 짙게 나타났으나 열수처리구에서는 가시적 변화를 발견할 수 없었다. 한편 부패과 발생률에 있어서 열수처리구가 축부병 등에 의한 짓무름 현상 및 곰팡이 발생정도를 가장 낮게 나타내었고, 관능검사에서도 열수처리구가 변색, 시듦, 광택 등의 외관 품질항목에서 유의적으로 우수하게 평가되었다. 결과적으로 중온 열수처리는 부지화 김귤의 수확후 저장유통중 부패과 발생률을 감소시키고 외관품질을 유지하는데 효과적인 전처리방법임을 확인할 수 있었다. 있었다.

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