• 제목/요약/키워드: 창상 치유

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Effect of ${\beta}$-glucan Originated from Aureobasidium on the Dermal Wound Repair in Vitro Model (생체외 모델에서 아우레오바지디움 유래 베타 글루칸이 피부창상 치유에 미치는 영향)

  • Lee, Jung-Woo;Kwon, Young-Sam;Jang, Kwang-Ho
    • Journal of Veterinary Clinics
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    • v.30 no.6
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    • pp.403-408
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    • 2013
  • The objective of the present study is to detect the effect of ${\beta}$-glucan originated from Aureobasidium on the proliferation and collagen production in human dermal fibroblast cells with wound repopulation in vitro. The proliferative effects were assessed using a MTT assay as well as cell counts at 24 and 48 hr after treatment. Hydroxyproline was measured as an index of procollagen production with reverse-phase high pressure liquid chromatography. Oncostatin M was used as a reference agent. In glucagon treated group, dose-dependent and significant increase of optical density or fibroblast cell numbers was demonstrated, when compared with those of control from 0.1 mg/ml concentration. In addition, the numbers of cells which had migrated into the wound defects were more significantly and dose-dependently increased than those of non-treated control. However, no meaningful effects on the procollagen production were observed.

Acellular Dermal Matrix for Wound with Large Dead Space in 3 Dogs (개의 큰 사강을 갖는 창상에서 무세포성 진피기질의 적용 3례)

  • Youp, Kyoung-A;Byeon, Ye-Eun;Lee, Sun-Tae;Kim, Hee-Jung;Cho, Ji-Young;Kweon, Oh-Kyeong;Kim, Jin-Young;Kang, Ke-Won;Kim, Wan-Hee
    • Journal of Veterinary Clinics
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    • v.27 no.3
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    • pp.299-301
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    • 2010
  • An acellular human dermal matrix (ADM) was applied to wounds from dogs with significant dead space and delayed healing. This treatment is typically effective for the treatment of wounds with subcutaneous dead space and injuries between muscular planes. The size of the dead space defect and the amount of wound discharge decreased rapidly with ADM treatment in the present study. The average time to disappearance of the dead space defect was 10 days. In addition, complications including severe inflammation were not seen in this case report.

Repair of the Traumatic Oronasal Communication in a Dog with a Palatal Prosthesis : a Case Report (개에서 창상성 구비강 개통의 아크릴 부목을 이용한 치유 증례)

  • Shim, Kyung-Mi
    • Journal of Veterinary Clinics
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    • v.26 no.6
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    • pp.641-643
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    • 2009
  • A 5-year-old intact female mixed dog was admitted to the Veterinary Teaching Hospital for reconstructive surgery of traumatic oronasal communication in the palatal region after suffering a facial gunshot injury. The surgical procedure involved making buccal mucosal flaps as well as a transposition flap of the hard palate mucoperiosteum from the tissue adjacent to the defect, followed by applying a prosthetic appliance to protect the surgical flaps. A satisfactory outcome was obtained using a palatal prosthesis.