• Title/Summary/Keyword: 집락분석

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Association between Ureaplasma urealyticum Colonization and Adverse Outcomes in Premature Infants (출생 시 Ureaplasma urealyticum 집락이 조산아의 임상 양상에 미치는 영향)

  • Yun, Jin-Sang;Chang, Sun-Jung;Jo, Heui-Seung;Lee, Kyu-Hyung
    • Neonatal Medicine
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    • v.16 no.1
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    • pp.47-54
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    • 2009
  • Purpose: Present evidences suggest that Ureaplasma urealyticum is a cause of pneumonia, septicemia, and bronchopulmonary dysplasia (BPD) in newborn infants, particularly those born prematurely. The purpose of this work was to examine the relationship between Ureaplasma urealyticum in the tracheal aspirates and adverse outcomes, such as BPD and early onset neonatal sepsis in premature infants. Methods: A polymerase chain reaction (PCR) was performed on tracheal aspirates collected within 24 hour after birth in 176 premature infants less than 35 weeks of gestation and admitted to the neonatal intensive care unit of Bundang CHA Hospital. Results: U. urealyticum was detected in 37 of 176 preterm infants (21.0%). Gestational age ($29^{+5}{\pm}2^{+5}$ wk vs. $30^{+6}{\pm}2^+{-5}$ wk, P=0.0l3) and birth weight (1.39${\pm}$0.44 kg vs. 1.59${\pm}$0.55 kg, P=0.037) were lower in the U urealyticum-positive group compared to the control group. The incidence of early onset neonatal sepsis (16.2% vs. 6.5%, P=0.045) and BPD (45.9% vs. 29.5%, P=0.047) was higher in the U urealyticum-positive group compared to the control group, but the severity of BPD was not different between two groups. However, multiple logistic regression analysis revealed that the presence of U. urealyticum was not independently related to the development of early onset neonatal sepsis and BPD. Conclusion: The results suggest that colonization of the lower respiratory tract by U. urealyticum might not be related to the development of neonatal sepsis and BPD directly in preterm infants.

Biological Hazard Analysis of Leaf Vegetables and Fruits According to Types of Cultivation and Distribution Systems (엽채류 및 과채류의 재배유형 및 유통경로별 생물학적 위해요소 조사)

  • Yu, Yong-Man;Youn, Young-Nam;Choi, In-Uk;Yuan, Xianglong;Lee, Young-Ha
    • Food Science and Preservation
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    • v.14 no.1
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    • pp.35-41
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    • 2007
  • As the consumption of environmentally friendly agricultural products increases, food safety is at the forefront of public health concerns. We analyzed the biological hazards of 26 species of leaf vegetables and 4 species of fruit according to types of cultivation (conventional or organic filming) and distribution system (giant retailers or organic food stores) using various culture media, automatic bacterial identification systems, and microscopy, Total bacterial count of unwashed agricultural product ranged from $5.2{\times}10^{3}\;to\;1.5{\times}10^{5}\;CFU/mL$ (from 0.1 g of agricultural products), and the average count dropped 25-fold (range, 8-60-fold) after water washing. Microbial levels of washed organic agricultural products were $6.0{\times}10^{2}-1.9{\times}10^{4}\;CFU/mL$, and were not significantly different f개m the microbial loads on conventionally farmed produce. There was no significant difference in bacterial count from agricultural produce purchased from giant retailers or organic food stores. Total microbial count of Chinese cabbage, welsh onion, red chicory and kale were comparatively high, and Enterobacter cloacae was isolated most frequently. Parasites were detected in agricultural products purchased from conventional farm products in the stores of giant retailers, and in organic food stores, and parasite prevalence was especially high in Chinese cabbages and welsh onion. The study indicated that cultivation methods and distribution systems did not cause significant differences in biological contamination levels of agricultural produce. Some vegetables and fruits were highly contaminated effective sanitizing methods to reduce these biological hazards are needed.

Comparison of a Closed with an Open Endotracheal Suction: Costs and the Incidence of Ventilator-associated Pneumonia (비용, 인공환기관련폐렴 발생 빈도에 있어서의 개방 기관내 흡인술에 대한 폐쇄 흡인술의 비교)

  • Jung, Jae Woo;Choi, Eun Hee;Kim, Jin Hee;Seo, Hyo Kyung;Choi, Ji Yeon;Choi, Jae Cheol;Shin, Jong Wook;Park, In Won;Choi, Byoung Whui;Kim, Jae Yeol
    • Tuberculosis and Respiratory Diseases
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    • v.65 no.3
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    • pp.198-206
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    • 2008
  • Background: Tracheobronchial suctioning using the closed suctioning system has physiological benefits for critically ill patients. Despite these benefits, there are concerns about increased colonization of tracheobronchial tree by pathogenic organisms. The cost is another hinder to the introduction of closed suction system. The aim of this study was to evaluate the incidence of colonization and ventilator associated pneumonia and the cost-effectiveness of closed suction compared with open suction. Methods: During separated one month period, patients admitted MICU were cared by multiple-use, open suction, single-use, open suction and multiple-use, closed suction method, consecutively. Costs, colonization of tracheobronchial tree by MRSA and the incidence of ventilator-associated pneumonia (VAP) were analyzed. Results: One-hundred and six patients were enrolled. Twenty patients were treated with multiple-use, open suction, while 42 and 44 patients were cared with single-use, open catheter and multiple-use, closed catheter, respectively. Colonization by MRSA and the incidence of VAP were not different among three ways of suctioning. The overall costs per patient per day for suctioning were $10.58 for multiple-use, open suction, $28.27 for single-use, open suction and $23.76 for multiple-use, closed suction. Conclusion: Multiple-use, closed suctioning, when suction catheters were changed every 48 hrs, has the similar incidence of colonization of MRSA and occurrence of VAP and is a cost-efficient way of endotracheal suction.

비례위험모형분석을 위한 한글멀콕스(HMULCOX)

  • Lee, Sang-Bok;Park, Eui-Jun
    • Journal of the Korean Data and Information Science Society
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    • v.7 no.1
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    • pp.145-159
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    • 1996
  • 다변량 발병시간자료는 각 개개 환자에게 있어 합병증이 발생되거나 혹은 유사 환자군(집락) 내의 발병시간이 상관되어진 생의학자료에서 흔히 볼 수 있다. HMULCOX는 그런 자료를 분석하기 위한 한글 통계 패키지 가운데 하나이다. 이 프로그램은 관련된 발병시간들이 독립이 아닐때에도 COX 비례 위험 모형의 주변확률분포를 계산해 준다. 주어진 조건으로는 주변확률모형의 기본위험율은 일정한 상수, 흑은 변수라도 관계없다. 또한 치료실패율의 치료변수들(공변량)의 효과에 대해 다양한 통계적 추론이 가능하다. 기본적으로 주변확률분포접근법으로 설계되었지만 HMULCOX는 여러 가지 추론 방법을 선택하는 데 일반적으로 충분하다. 이 프로그램으로 2개의 예를 들어 실행하겠다.

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Respiratory Microbiome in Children (소아의 호흡기 미생물군 유전체)

  • Kim, Dong Hyun
    • Pediatric Infection and Vaccine
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    • v.26 no.3
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    • pp.129-139
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    • 2019
  • The human respiratory tract hosts both pathogenic and commensal bacteria. The development of well-conserved 16S rRNA sequencing and culture-independent techniques has enabled many achievements in the study of the human microbiome. Microbial composition of the respiratory tract in early childhood has been shown to correlate to respiratory health in later stages of life. This review highlights current understandings of respiratory microbiota development in healthy children, examples of microbial interactions, impacts on the host immune system, and the relationship between respiratory tract microbiome and respiratory health.

The Effects of Organizational Culture of Aviation Security Workers on Organizational Effectiveness (항공보안업무 종사자의 조직문화가 조직유효성에 미치는 영향)

  • Cho, Yong-Hoon;Lee, Chi-Young;Park, Su-Hyeon
    • Proceedings of the Korean Society of Disaster Information Conference
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    • 2023.11a
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    • pp.49-50
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    • 2023
  • 본 연구는 항공보안업무 종사자의 조직문화가 조직유효성에 미치는 영향을 규명하기 위하여 항공보안검색요원 300명을 대상으로 집락표본추출법(cluster sampling method)을 통해 자료를 수집하여 분석하였다. 수집된 설문지 중 표기오류, 누락, 전체 항목의 동일 표기 등을 분류하여 최종적으로 272부를 분석에 사용하였다. 연구결과 조직문화는 조직유효성에 정(+)적인 영향을 미치는 것으로 나타났다. 조직문화의 하위요인인 합리문화, 합의문화, 발전문화는 조직유효성의 하위요인인 직무만족에 영향을 미치는 것으로 나타났으며, 위계문화는 영향을 미치지 않는 것으로 나타났다. 또한 합의문화, 위계문화, 발전문화 순으로 조직몰입에 영향을 미쳤으나 합리문화는 통계적으로 유의한 영향을 미치지 않는 것으로 나타났다.

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Understanding Complex Design Features via Design Effect Models (설계효과모형을 통한 설계요소의 유용성 이해)

  • Park, Inho
    • The Korean Journal of Applied Statistics
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    • v.28 no.6
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    • pp.1217-1225
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    • 2015
  • Survey research, data is commonly collected through a sample design with complex design features that allow the relative efficiency on the precision of an estimator to be measured using the concept of the design effect compared to simple random sampling as a reference design. This concept is most useful when the design effect can be expressed as a function of various design features. We propose a design effect formula suitable under a stratified multistage sampling by generalizing Gabler et al. (1999, 2006)'s approaches for multistage sampling. Its use can either guide improvement in the design efficiency when in design stage or enable the evaluation of the adopted design features afterwards.

Physicochemical Properties and Fatty Acid Composition of Korean Margarines (국산 마가린의 물리화학적 성질 및 지방산 조성에 관한 연구)

  • 김정원;황인경;안승요
    • Korean journal of food and cookery science
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    • v.2 no.1
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    • pp.11-16
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    • 1986
  • Physicochemical properties and fatty acid composition of 12 randomly selected Korean margarines were determined, which were stored within one month since manufactured. Average moisture and fat contents of margarines were 15.09% ana 77.92% respectively. Melting point was ranged from 33.23$^{\circ}C$ to 42. 13$^{\circ}C$. Acid value and peroxide value were very low. iodine value was ranging from 59.65 to 86. 05. As a result of cluster analysis using the data of fatty acid composition, margarines divided into two groups according to their package condition, soft and hard type, were also classified into the same two groups. This probably implies that the raw materials of margarines between two groups were not the same. O1eic acid (18:1) and palmitic acid (16:0) in soft and hard type margarines respectively were the highest. Linoleic acid (18 : 2) contents showed large differences among margarines. Most of the margarines had little linolenic acid (18:3) . Generally essential fatty acid contents of Korean margarines were higher than those of the past but they didn't reach the levels of margarines made in some foreign countries.

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Classification of Public Perceptions toward Smog Risks on Twitter Using Topic Modeling (Topic Modeling을 이용한 Twitter상에서 스모그 리스크에 관한 대중 인식 분류 연구)

  • Kim, Yun-Ki
    • Journal of Cadastre & Land InformatiX
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    • v.47 no.1
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    • pp.53-79
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    • 2017
  • The main purpose of this study was to detect and classify public perceptions toward smog disasters on Twitter using topic modeling. To help achieve these objectives and to identify gaps in the literature, this research carried out a literature review on public opinions toward smog disasters and topic modeling. The literature review indicated that there are huge gaps in the related literature. In this research, this author formed five research questions to fill the gaps in the literature. And then this study performed research steps such as data extraction, word cloud analysis on the cleaned data, building the network of terms, correlation analysis, hierarchical cluster analysis, topic modeling with the LDA, and stream graphs to answer those research questions. The results of this research revealed that there exist huge differences in the most frequent terms, the shapes of terms network, types of correlation, and smog-related topics changing patterns between New York and London. Therefore, this author could find positive answers to the four of the five research questions and a partially positive answer to Research question 4. Finally, on the basis of the results, this author suggested policy implications and recommendations for future study.

Isolation and Characterization of Bacteriolytic Wild Myxobacteria (용균성 야생 점액세균의 분리)

  • 박수연;이봉수;김지훈;이차율;장은혜;조경연
    • Microbiology and Biotechnology Letters
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    • v.32 no.3
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    • pp.218-223
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    • 2004
  • Myxobacteria are Gram-negative soil bacteria known to be a rich source of potentially useful secondary metabolites. We have isolated 204 strains of bacteriolytic myxobacteria from soil samples collected in Korea and determined their 16S rRNA sequences. Sequence analysis of the partially determined 16S rRNA sequences has suggested that 132 isolates (65% of total isolates) belong to the genus Myxococcus and 59 isolates (29% of total isolates) belong to the genus Corallococcus. Meanwhile, 4 isolates appear to be Archangium spp. and the other 4 isolates appear to be Stigmatella spp. Genera of the remained 5 isolates have not been identified because their 16S rRNA sequences are distantly related to those of known myxobacteria.