• 동물약계
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• no.30
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• pp.4-5
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• 1996

1. 신규허가 2. 제조(수입)업 허가사항 변경 3. 사료첨가제 임가공에 대한 질의회신 4. 양축농가 지도계몽 실적조사 5. 가축질병중앙예찰협의회 개최 6. 가축전염병 발생정보 7. 과대광고 금지 8. 건의서 회신 9. 생물학적제제 유통관리 10. 유당사용실적 보고 11. 한국우병학회 창립 12. 대한수의사회 책자발간 13. 돼지 인공수정 책자발간 14. 국검품 수입절차 안내 15. 유방염 치료용 연고제제 색소첨가 16. 제 2 차 이사회 개최

• 동물약계
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• no.34
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• pp.3-4
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• 1996

[ $\cdot$ ]클로람페니콜, 타이로신 복합 주사제 유효기간 잠정 단축 $\cdot$동물용의약품유통시 품질관리 철저 지시 $\cdot$가축질병 병성감정 실시기관 지정 $\cdot$동물용의약품 품질관리 우수업체 지정 $\cdot$신규 동물용의약품등 수입자 확인 $\cdot$동물용의약품등 영업사원 및 판매점 교육철저 지시 $\cdot$가축전염병 발생정보 발표 $\cdot$클로람페니콜제제 애완동물용 전용 포장단위 변경의 건 $\cdot$소 유방염 치료용 연고제 색소첨가의 건 $\cdot$제2차 수출촉진 협의회 개최 $\cdot$동물용의약품등 수입 품목신고 현황

• Journal of the Korean Society of Food Science and Nutrition
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• v.21 no.2
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• pp.219-230
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• 1992

Nutrients and drugs are similar to biological fate, such as absorption, metabolism and excretion. Such procedure may interact with nutrients and drugs. Drugs can influence nutrient absorption, metabolism or excretion ; the effects may impair the nutritional status of a patient. Specific nutrient, nutritional status, or dietary factors alter drug utilization. Therefore, medicated patients need to be aware of good nutrition practices and to understand the importance of dietary modifications associated with certain diseases. A nutritious and well balanced diet not only makes an important contribution to the health of those patients, but also reduces the risk of nutrition disorders or altered the pharmacological action of drugs.

• Journal of the Korea Society of Computer and Information
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• v.27 no.5
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• pp.21-28
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• 2022

All health problems that occur in the circulatory system are refer to cardiovascular illness, such as heart and vascular diseases. Deaths from cardiovascular disorders are recorded one third of in total deaths in 2019 worldwide, and the number of deaths continues to rise. Therefore, if it is possible to predict diseases that has high mortality rate with patient's data and AI system, they would enable them to be detected and be treated in advance. In this study, models are produced to predict heart disease, which is one of the cardiovascular diseases, and compare the performance of models with Accuracy, Precision, and Recall, with description of the way of improving the performance of the Decision Tree(Decision Tree, KNN (K-Nearest Neighbor), SVM (Support Vector Machine), and DNN (Deep Neural Network) are used in this study.). Experiments were conducted using scikit-learn, Keras, and TensorFlow libraries using Python as Jupyter Notebook in macOS Big Sur. As a result of comparing the performance of the models, the Decision Tree demonstrates the highest performance, thus, it is recommended to use the Decision Tree in this study.

• Journal of Biomedical Engineering Research
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• v.23 no.6
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• pp.451-458
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• 2002

Osteoporosis is a systemic skeletal disease caused by low bone mass and the decrease of bone density in the microstructure of trabecular bone. Drug therapy(PTH Parathyroid hormone) may increase the trabecular thickness and thus bone strength. Vertebroplasty is a minimally invasive surgery foy the treatment of osteoporotic vertebral compression fracture. This Procedure includes Puncturing vertebrae and filling with Polymethylmethacrylate(PMMA). Although altering recommended monomer-to-Powder ratio affects material properties of bone cement, clinicians commonly alter the mixture ratio to decrease viscosity and increase the working time. The Purposes of this study were to analyze the effect of 4he monomer-to-powder ratio on the mechanical characteristics of trabecular. In this paper, the finite element model of human vertebral trabecualr bone was developed by modified Voronoi diagram, to analyze the relative effect of hormone therapy and vertebroplasty at the treatment of osteoporotic vertebrae. Trabeuclar bone models for vertebroplasty with varied monomer-to-Powder ratio(0.40∼1.07 ㎖/g) were analyzed. Effective modulus and strength of bone cement-treated models were approximately 60% of those of intact models and these are almost twice the values of hormone-treated models. The bone cement models with the ratio of 0.53㎖/g have the maximum modulus and strength. For the ratio of 1.07㎖/g, the modulus and strength were minimum(42% and 49% respectively) but these were greater than those for drug therapy. This study shows that bone cement treatment is more effective than drug therapy. It is found that in vertebroplasty, using a monomer-to-powder ratio different from that recommended by manufacturer nay significantly not only reduce the cement's material Properties but also deteriorate the mechanical characteristics of osteoporotic vertebrae.

• Korean Journal of Biological Psychiatry
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• v.23 no.2
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• pp.48-56
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• 2016

Alzheimer's disease (AD) is a neurodegenerative disorder in which neuronal loss causes cognitive decline and other neuropsychiatric problems. It can be diagnosed based on history, examination, and appropriate objective assessments, using standard criteria such as the Diagnostic and Statistical Manual of Mental Disorders or the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA). Brain imaging and biomarkers are making progress in the differential diagnoses among the different disorders. The cholinesterase inhibitors, donepezil, rivastigmine and galantamine and N-methyl-D-aspartate receptors antagonist memantine are approved by the US Food and Drug Administration for AD. Recently some acetylcholinesterase inhibitors gained approval for the treatment of severe AD and became available in a higher dose formulation or a patch formulation. Optimal care in AD is multifactorial and it should include early diagnosis and multidisciplinary care with pharmacological and nonpharmacological interventions including exercise interventions, cognitive interventions and maintenance of social networks.

• Proceedings of the KAIS Fall Conference
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• 2009.12a
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• pp.484-486
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• 2009

본 연구는 본 연구는 입원중인 뇌졸중 환자들이 겪는 경제적 스트레스 및 우울이 삶의 질에 미치는 영향을 알아보기 위해 대전에 소재하고 있는 대학병원, 종합병원, 재활센터 등에서 치료를 받고 있는 뇌졸중환자 209명으로 하였다. 자료수집방법은 각각 구조화된 설문지를 통해 1:1 면접조사를 실시하였다. 연구도구는 경제적-불편감척도(Gore, 1978)와 Arruda J.E가 개발한 시각상사척도와 GHO-60(Goldberg, 1972), MOS SF-36(Ware 등, 1992)을 김건엽(2002)이 표준화한 23문항 중 삶의 질을 측정하는 12문항을 수정, 변경하여 사용하였다. 수집된 자료는 SPSS(Statistical for the Social Science)12.0을 이용하여 분석하였고, 뇌졸중 환자의 일반적 특성, 물리치료 관련 특성, 질병 관련 특성, 경제적 스트레스, 독립변수로 빈도와 백분율, 평균과 표준편차를 구하고, 전체 연구 대상자의 기술 역학적 특성을 파악하기 위하여 기술통계와 일반적 특성, 물리치료, 질병관련 특성에 따른 환자의 경제적 스트레스, 우울, 삶의 질과의 차이를 알아보기위해 t-검정과 일원분산분석(analysis of variance, ANOVA)을 사용하였다. 발병 후 가계수입(p<0.05), 재정적 압박 수준(p<0.01), 삶의 질(p>0.05), 생활수준(p<0.05)이 통계적으로 유의한 것으로 나타났다. 감정상태가 낮고 생활수준과 재정적 압박 정도가 매우 심할 경우 더 유의하게 경제적 스트레스 점수가 높게 나왔다. 이는 뇌졸중환자가 겪는 경제적 스트레스 요인이 우울과 함께 중요한 영향을 미치며,인구분석학적 결과를 보더라도 가구의 소득수준이 큰 영향을 미치는 것으로 건강에 대한 재정적 부담, 가족으로부터 소외 일과에의 영향, 올가미를 쓴 느낌 이상의 결과로 볼 때 본 연구에서는 시각적 감정 상태, 재정적 압박상태, 우울, 생활수준, 질병 관련 특성, 삶의 질을 위주로 하여 경제적 스트레스 관련 요인을 살펴본 결과 후속연구에서는 보다 정확한 경제적 부담 수준을 측정하고 더불어 보다 객관적인 경제적 스트레스를 측정할 수 있는 도구를 이용하여 조사를 한다면 임상적으로 중요한 자료가 될 것이다. 또한 뇌졸중 환자의 경제적 스트레스를 감소하고 삶의 질 수준을 증진시킬 수 있는 치료적 중재의 개발이 절실히 요구된다.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.05a
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• pp.452-455
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• 2022

4차 산업혁명의 확산으로 의학계에서도 딥러닝 기술을 이용한 질병의 치료결과 예측 연구가 활발하다. 이와 관련, 일부 연구에서 국소적인 환자 데이터의 활용으로 인해 도출된 연구 결과의 일반화가 어려웠으며 예측률 제고를 위해 특정 딥러닝 알고리즘을 중심으로 한 실험이 추진되어 다양한 알고리즘별 예측률의 비교·분석 결과를 제시하는 연구도 미흡하였다. 이에, 건강보험심사평가원의 대규모 진료 정보와 다종의 알고리즘을 제공하는 AutoML을 이용, 사망률이 높은 80대·90대 노령자 대상 폐암 진단 후 84개월간의 사망률을 예측하는 Decision Tree 등 5개 알고리즘별 모델을 생성하고 이를 활용, 사망률의 예측 성능을 비교하고 사망률에 영향을 미치는 요인에 대한 분석 결과를 도출하였다.

• The Korean Society of Law and Medicine
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• v.24 no.2
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• pp.3-31
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• 2023

Der Begriff der Heilkundeausübung ist im positiven Recht in Korea nirgends festgelegt. Der wurde jedoch indirekt durch die Auslegung der Heilkundeausübung ohne Erlaubnis gemäß § 27 Abs. 1 des "Medizingesetzes" geregelt. In der Vergangenheit beschränkte der kOGH(the Supreme Court of Korea) die Heilkundeausübung auf die "Behandlung von Krankheiten und stellte fest, dass "medizinische und technische Maßnahmen, die keine pathologischen Symptome oder Funktionsdefizite im Körper voraussetzen, nicht zur Heilkundeausübung gehören." Danach änderte der kOGH seine Rechtsprechung auf "Vorbeugung oder Behandlung von Krankheiten durch Durchführung ärztlicher Untersuchungen, Optometrie, Verschreibung, Medikation oder chirurgischer Eingriffe auf der Grundlage von Erfahrung und Fähigkeiten, die auf medizinischem Fachwissen basieren, und anderer Gesundheitsfürsorge, definiert "medizinische Maßnahmen" als "eine Handlung, die eine gesundheitliche Gefahr darstellen kann, sofern diese nicht von einem Mediziner durchgeführt wird". Der Begriff der Heilkundeausübung in der Rechtsprechung ist einerseits zu abstrakt und kann eine Leerformel sein, andererseits kann seine Einschränkung eine Gefahr für die öffentliche Gesundheit erbringen. Daher besteht Bedarf an einem Kriterium, das dar derzeitige Begriff der Heilkundeausübung entsprechend dem gesetzgeberischen Ziel reduzieren kann, das Risiko für das Leben, den Körper oder die öffentliche Gesundheit von Menschen zu verhindern, das durch die Durchführung medizinischer Arbeiten durch nichtmedizinisches Personal entstehen kann. Um ein Kriterium vorzustellen, das das aktuelle Konzept der Heilkundeausübung reduzieren kann, werden in diesem Artikel das positive Recht, Theorien und Rechtsprechung zum Begriff der Heilkundeausübung in Deutschland untersucht und nach einer Alternative gesucht.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.406-409
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• 2022

In recent years, the developments in technologies, such as AI systems, Blockchain, VR/AR, 3D printing, robotics, and nanotechnology, are reshaping the future of healthcare right before our eyes. And also, healthcare has seen a paradigm shift towards prevention-oriented medicine, with a focus on consumers requirements. The spread of infectious diseases such as Covid-19 have altered the definition of healthcare and treatment facilities, necessitating immediate action to redesign hospitals' physical environments, adapt communication models to address social distancing requirements, implement virtual health solutions, and establish new clinical protocols. Hospitals, which have traditionally served as the hub of healthcare systems, are pursuing or being forced to reestablish themselves against this landscape. Rather than only treating ailments, future healthcare is predicted to focus on wellness and prevention. In personalized care, long-term prevention strategies, remote monitoring, early diagnosis, and detection are critical. Given the growing interest in smart healthcare defined by these modern technologies, this study looked into the definitions and service kinds of smart healthcare. The background and technical aspects of smart hospitals were also explored through a literature review.