• 베이커리
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• no.4 s.321
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• pp.120-121
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• 1995

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.922-927
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• 2004

Abrasive waterjet (AWJ) cutting is an emerging technology for precision cutting of difficult-to-machining materials with the distinct advantages of no thermal effect, high machinability, high flexibility and small cutting forces. This paper investigated theoretical and experimental cutting characteristics associated with abrasive waterjet cutting of quartz GE214. It is shown that the proper variations of several cutting parameters such as waterjet pressure, cutting speed and cutting depth improve the roughness on workpiece surfaces produced by AWJ cutting. From the experimental results by AWJ cutting of quartz GE214, the optimal cutting conditions to improve the surface roughness were proposed and discussed.

• Journal of Welding and Joining
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• v.23 no.1
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• pp.86-93
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• 2005

Abrasive waterjet (AWJ) can provide a more effective means for precision of difficult -to-machining materials such as ceramics and titanium alloys. The present study is focused on the surface roughness of abrasive waterjet cut surfaces. This paper investigated theoretical and experimental surface characteristics associated with abrasive waterjet cutting of titanium alloy Gr2. It is shown that the proper variations of several cutting parameters such as waterjet cutting pressure, cutting speed and cutting depth improve the roughness and characteristics on specimen surfaces produced by AWJ cutting. From the experimental results by AWJ cutting of titanium alloy Gr2, the optimal cutting conditions to improve the surface roughness and precision were proposed and discussed.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.2
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• pp.118-126
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• 2005

Abrasive waterjet (AWJ) cutting is an emerging technology for precision cutting of difficult-to-machining materials with the distinct advantages of no thermal effect, high machinability, high flexibility and small cutting forces. This paper investigated theoretical and experimental cutting characteristics associated with abrasive waterjet cutting of quartz GE214. It is shown that the proper variations of several cutting parameters such as waterjet cutting pressure, cutting speed and cutting depth improve the roughness on workpiece surfaces produced by AWJ cutting. From the experimental results by AWJ cutting of quartz GE214, the optimal cutting conditions to improve the surface roughness and precision were proposed and discussed.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.25-30
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• 2004

In this paper, the compensation of interfacial scatter due to adhesive layer and adherend thickness ratio variation was applied to improve measuring precision by calculating ultrasonic attenuation coefficient in the Al/Epoxy dissimilar bonded components. The optimum condition of theoretical value and experimental measuring accuracy by the ultrasonic method in the Al/Epoxy dissimilar bonded components have been investigated. From the experimental results, we proposed a measurement method of the interfacial crack lengths by the ultrasonic attenuation coefficient and discussed it.

• Journal of Life Science
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• v.29 no.6
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• pp.747-753
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• 2019

Cognitive decline is characterized by reduced long-/short-term memory and attention span, and increased depression and anxiety. Such decline is associated with various degenerative brain disorders, especially Alzheimer's disease (AD) and Parkinson's disease (PD). The increases in elderly populations suffering from cognitive decline create social problems and impose economic burdens, and also pose safety threats; all of these problems have been extensively researched over the past several decades. Possible causes of cognitive decline include metabolic and hormone imbalance, infection, medication abuse, and neuronal changes associated with aging. However, no treatment for cognitive decline is available. In neurodegenerative diseases, changes in the gut microbiota and gut metabolites can alter molecular expression and neurobehavioral symptoms. Changes in the gut microbiota affect memory loss in AD via the downregulation of NMDA receptor expression and increased glutamate levels. Furthermore, the use of probiotics resulted in neurological improvement in an AD model. PD and gut microbiota dysbiosis are linked directly. This interrelationship affected the development of constipation, a secondary symptom in PD. In a PD model, the administration of probiotics prevented neuron death by increasing butyrate levels. Dysfunction of the blood-brain barrier (BBB) has been identified in AD and PD. Increased BBB permeability is also associated with gut microbiota dysbiosis, which led to the destruction of microtubules via systemic inflammation. Notably, metabolites of the gut microbiota may trigger either the development or attenuation of neurodegenerative disease. Here, we discuss the correlation between cognitive decline and the gut microbiota.