• Journal of the Korean Society of Radiology
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• v.84 no.1
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• pp.150-169
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• 2023

Multiple myeloma (MM) is a malignant hematologic disease caused by the proliferation of clonal plasma cells in the bone marrow, and its incidence is increasing in Korea. With the development of treatments for MM, the need for early diagnosis and treatment has emerged. In recent years, the International Myeloma Working Group (IMWG) has been constantly revising the laboratory and radiological diagnostic criteria for MM. In addition, as whole-body MRI (WBMR) has been increasing used in the diagnosis and treatment response evaluation of patients with MM, the Myeloma Response Assessment and Diagnosis System (MY-RADS) was created to standardize WBMR image acquisition techniques, image interpretation, and response evaluation methods. Radiologists need to have a detailed knowledge of the features of MM for accurate diagnosis. Thus, in this review article, we describe the imaging method for MM according to the latest IMWG guidelines as well as the image acquisition and response evaluation technique for WBMR according to MY-RADS.

• The Journal of the Acoustical Society of Korea
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• v.42 no.5
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• pp.429-440
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• 2023

This study explores recent research trends and potential applications of ultrasound optical imaging-based multimodal technology. Ultrasound imaging has been widely utilized in medical diagnostics due to its real-time capability and relative safety. However, the drawback of low resolution in ultrasound imaging has prompted active research on multimodal imaging techniques that combine ultrasound with other imaging modalities to enhance diagnostic accuracy. In particular, ultrasound optical imaging-based multimodal technology enables the utilization of each modality's advantages while compensating for their limitations, offering a means to improve the accuracy of the diagnosis. Various forms of multimodal imaging techniques have been proposed, including the fusion of optical coherence tomography, photoacoustic, fluorescence, fluorescence lifetime, and spectral technology with ultrasound. This study investigates recent research trends in ultrasound optical imaging-based multimodal technology, and its potential applications are demonstrated in the biomedical field. The ultrasound optical imaging-based multimodal technology provides insights into the progress of integrating ultrasound and optical technologies, laying the foundation for novel approaches to enhance diagnostic accuracy in the biomedical domain.

• Journal of Korea Multimedia Society
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• v.8 no.4
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• pp.482-491
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• 2005

In this paper, we proposed the microcalcification detection algorithm which is based on wavelet transform and automatic thresholding method in the X-ray mammographic images. Digital X-ray imaging system is essential equipment in the field diagnosis and is widely used in the various fields such as chest, fracture of a bone, and dental correction. Especially, digital X-ray mammographic imaging is known as the most important method to diagnose the breast cancer, many researches to develop the imaging system are processing in country. In this paper, we proposed a microcalcifications detection algorithm necessary in the early phase of breast cancer diagnosis and showed that a algorithm could effectively detect microcalfication and could aid diagnosis-radiologist.

• Annual Conference of KIPS
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• 2020.11a
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• pp.928-930
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• 2020

본 논문은 인공지능 플랫폼 기반의 요로결석 진단을 위한 CT 영상 데이터 자동판독 시스템에 대해 기술하고자 한다. 제안한 시스템은 웹 기반의 플랫폼을 기반으로 하며, 인공지능 기반의 진단 알고리즘을 장착하여 빠르게 요로결석 환자의 스크리닝에 목적을 두고 있다. 병원정보시스템의 PACS와 EMR과 연계와 Deep learning 진단 알고리즘을 적용한 요로결석 자동판독 시스템을 개발하였다. 특히, 기 구축된 인공지능 플랫폼을 통해 추출한 데이터셋을 기반으로 진단 알고리즘 개발 방법과 수행 결과를 보인다. 제안한 시스템은 요로결석 진단과 수술여부에 의사결정지원 시스템으로 임상에서 활용될 것으로 기대하고 있다.

• Journal of KIISE
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• v.42 no.7
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• pp.910-918
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• 2015

This paper presents a parameter visualization technique to overcome the limitation of the naked eye in contrast-enhanced ultrasonography. A method is also proposed to compensate for the distortion and noise in ultrasound image sequences. Meaningful parameters for diagnosing liver disease can be extracted from the dynamic patterns of the contrast enhancement in ultrasound images. The visualization technique can provide more accurate information by generating a parametric image from the dynamic data. Respiratory motions and noise from micro-bubble in ultrasound data may cause a degradation of the reliability of the diagnostic parameters. A multi-stage algorithm for respiratory motion tracking and an image enhancement technique based on the Markov Random Field are proposed. The usefulness of the proposed methods is empirically discussed through experiments by using a set of clinical data.

• Journal of the Korean Society of Radiology
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• v.84 no.1
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• pp.15-33
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• 2023

The liver imaging reporting and data system (LI-RADS) has been developed with the support of the American College of Radiology to standardize the diagnosis and evaluation of treatment response of hepatocellular carcinoma (HCC). The CT/MRI LI-RADS version 2018 has been incorporated in the American Association for the Study of Liver Diseases guidance. This review examines the effect of CT/MRI LI-RADS on the standardized reporting of liver imaging, and the evidence in diagnosing HCC and evaluating treatment response after locoregional treatment using CT/MRI LI-RADS. The results are compared with other HCC diagnosis guidelines, and future directions are described.

• Journal of the Korean Society of Radiology
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• v.83 no.5
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• pp.1090-1103
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• 2022

Purpose To evaluate the diagnostic performance of digital breast tomosynthesis (DBT) with the two-dimensional synthesized mammogram (2DSM), compared to full-field digital mammography (FFDM), for suspicious microcalcifications in the breast ahead of stereotactic biopsy and to assess the diagnostic image visibility of the images. Materials and Methods This retrospective study involved 189 patients with microcalcifications, which were histopathologically verified by stereotactic breast biopsy, who underwent DBT with 2DSM and FFDM between January 8, 2015, and January 20, 2020. Two radiologists assessed all cases of microcalcifications based on Breast Imaging Reporting and Data System (BI-RADS) independently. They were blinded to the histopathologic outcome and additionally evaluated lesion visibility using a fivepoint scoring scale. Results Overall, the inter-observer agreement was excellent (0.9559). Under the setting of category 4A as negative due to the low possibility of malignancy and to avoid the dilution of malignancy criteria in our study, McNemar tests confirmed no significant difference between the performances of the two modalities in detecting microcalcifications with a high potential for malignancy (4B, 4C, or 5; p = 0.1573); however, the tests showed a significant difference between their performances in detecting microcalcifications with a high potential for benignancy (4A; p = 0.0009). DBT with 2DSM demonstrated superior visibility and diagnostic performance than FFDM in dense breasts. Conclusion DBT with 2DSM is superior to FFDM in terms of total diagnostic accuracy and lesion visibility for benign microcalcifications in dense breasts. This study suggests a promising role for DBT with 2DSM as an accommodating tool for stereotactic biopsy in female with dense breasts and suspicious breast microcalcifications.

• Annual Conference of KIPS
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• 2006.11a
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• pp.609-612
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• 2006

본 연구는 진단용 DNA 칩의 자동판독 시스템을 제안하는 것을 목적으로 한다. 일반적인 자동판독 시스템의 사양을 정의하고 그 구현방법을 제안하였다. 응용 예로서 자궁경부암 진단용 DNA 칩을 대상으로 GenePix 스캐너 프로그램 환경에 적용하였다. 영상획득은 GenePix 의 라이브러리를 사용하여 HTML 언어로 구현하였고, 영상의 판단과 보고서 생성은 Microsoft Visual C++ 6.0를 사용하여 COM 형태로 구현하였다. 결과 보고서는 한글 2002 문서에 환자 정보와 결과 정보 등에 해당하는 곳에 미리 정의된 표지문자열들을 삽입하여 템플릿을 만들었다. 판독 시스템은 템플릿을 읽어들여 처리 결과의 내용으로 표지문자열들을 치환하여 보고서를 생성하였다. 제안한 시스템을 통해서 스캐닝을 통한 영상획득, 영상읠 판독, 결과 보고서 생성으로 구성된 전체 판독과정이 사용자의 개입 없이 자동으로 처리될 수 있었다. 본 시스템은 기존에 수작업을 자동화여 판독 시간을 단축하고 판독 기준을 정량화하여 진단용 DNA 칩이 대량검사 활용되는 공헌할 것으로 기대된다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2006.05a
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• pp.239-242
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• 2006

골다공증은 해면골의 골소주 두께 감소 및 파단에 기인한 전체적인 골질이 저하되는 질병이다. 골다공증을 예방과 조기진단을 하기 위해서는 골밀도를 측정하여야 한다. 보다 나은 이미지를 얻기 위해 Digital X-Ray로 골밀도를 측정하여 영상 처리하기 위한 방법을 제시한다. 먼저 디지털 센서에서 증감지와 렌즈간 거리가 가까워서 증감지의 중심과 주변부의 광 경로차이가 발생하므로 왜곡이 발생하는데 이를 균일화하여야 한다. 그리고 X-Ray장비의 조건에 따라 영상에 많은 차이를 보이므로 영상의 밝기를 보정하는 과정이 필수적이다.

• The Journal of the Korea Contents Association
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• v.11 no.3
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• pp.18-25
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• 2011

In a manufacturing process of metal coins, surface defects of coins are manually detected. This paper describes an new method for detecting surface defects of metal coins on a moving conveyor belt using image processing. This method consists of multiple procedures: segmentation of a coin from the background, alignment of the coin to the model, projection of the aligned coin to the best eigen image space, and detection of defects by comparison of the projection error with an adaptive threshold. In these procedures, the alignement and the projection are newly developed in this paper for the detection of coin surface defects. For alignment, we use the histogram of the segmented coin, which converts two-dimensional image alignment to one-dimensional alignment. The projection reduces the intensity variation of the coin image caused by illumination and coin rotation change. For projection, we build multiple eigen image spaces and choose the best eigen space using estimated coin direction. Since each eigen space consists of a small number of eigen image vectors, we can implement the projection in real- time.