• Title/Summary/Keyword: 진단율

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Influence of Prognostic Factors on Survival Rate of Medulloblastoma Patient with Chemotherapy (항암치료를 받은 수모세포종환아에서 예후인자들이 생존률에 미치는 영향)

  • Shin, Kyung Mi;Choi, Sung Yeon;Won, Sung Chul;Yang, Chang Hyun;Lyu, Chuhl Joo;Suh, Chang Ok;Choi, Joong Uhn;Kim, Byung Soo
    • Clinical and Experimental Pediatrics
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    • v.46 no.2
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    • pp.178-182
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    • 2003
  • Purpose : Brain tumors are the second most common tumor in childhood, and medulloblastomas comprise 15-25% of brain tumors. The well known prognostic factors are age at diagnosis, stage of disease, and extent of surgical excision. In this study, we analysed the prognostic factors in patients who received chemotherapy after excision. Methods : We reviewed the medical records of 61 patients who received chemotherapy among the 94 patients who were diagnosed and treated between Jan 1985 and Sep 2001 in the Department of Pediatrics and Neurosurgery at Severance Hospital. Results : Among the total survival rate of patients who underwent chemotherapy, the 3-yr progression-free survival rate was $66.5{\pm}6.3%$ and the 15-yr progression-free survival rate was $60.3{\pm}6.7%$. The progression-free survival rate for patients with age at diagnosis over 3 yrs old and under 3 yrs old, was $64.5{\pm}7.7%$ and $48.2{\pm}12.9%$ respectively and there was no statistically significant difference. The survival rate of the high vs low risk group by staging was $72.7{\pm}10.5%$ and $54.6{\pm}8.3%$ respectively, and there was no significant difference. The survival rate of patients with total removal vs subtotal removal was $65.8{\pm}11.8%$ and $56.8{\pm}8.2%$ respectively, showing no statistical difference. Conclusion : The reason there is no difference in survival rate according to the traditional prognostic factors is that chemotherapy has improved not only the total survival rate but also the survival rate in patients with poor traditional prognostic factors. So, sufficient removal of tumor followed by proper chemotherapy and radiotherapy is an important factor which influences the survival rate of medulloblastoma patients.

An Experimental Study on the Quality Properties of High Strength Concrete by the Replacement Ratio SFFB as Substitutes of Silica-fume (실리카 흄 대체재로 활용 가능한 SFFB의 치환율에 따른 고강도 콘크리트의 품질특성에 관한 실험적 연구)

  • Lim, Byung-Hoon;Lee, Sang-Soo;Yun, Hyun-Do;Yoon, Gil-Ho
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.14 no.5
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    • pp.87-92
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    • 2010
  • This study set up 25, 35% for silica fume, SFFB's 2 level and water-combination material ratio, silica fume 10% for substitution ratio, and 4 level of SFFB 5, 10, 15(%) in order to compare and analyze the quality characteristic of ultra high strength concrete according to the substitution ratio of silica fume free binder (SFFB) that can be utilized as a substitute material for silica fume. As a result of an experimentation, the lower water-combination material ratio was, the higher addition ratio of high performance water-reducing agent for securing target liquidity increased, and it indicated the tendency that addition ratio of high performance water-reducing agent decreases because of material characteristic that SFFB has a lower absorptiveness than silica fume. The best strength was shown when SFFB substitution ratio is 10% at compressive strength and when substitution ratio is 15% at tensile strength, and it was indicated that at autogenous shrinkage contraction decreases compared to Plain(SF) regardless of substitution ratio of W/B and SFFB.

Calculation of Shielding Rate of Radiation Protective Equipment Using the X-ray Spectrum of IPEM Report-78 (IPEM Report-78의 엑스선 스펙트럼을 이용한 방사선 방호장비의 차폐율 계산)

  • Han, Dong-Hyun
    • Journal of the Korean Society of Radiology
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    • v.15 no.5
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    • pp.755-760
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    • 2021
  • In this study, the shielding rate of major X-ray protective equipment used in the medical environment was calculated using X-ray spectrum data emitted from the diagnostic X-ray generator of The Institute of Physics and Engineering(IPEM) Report-78, and the applicability of radiation protection was investigated. Radiation shielding rates were calculated through reduction rates of air-kerma and total intensity for lead apron (0.3 mmPb), thyroid shield (0.5 mmPb), lead goggles (0.5 mmPb), and lead glass (1.8, 2.7, 3.3 mmPb) used for diagnostic X-ray protection. As a result, the shielding rate calculated as the air kerma reduction rate ranged from 96.31 to 100% at 80 kV, and 90.35 to 100% at 120 kV. In addition, the results of this calculation were well matched with the results of previous studies measuring the actual shielding rate, and it is expected that the X-ray spectrum data of IPEM Report-78 can be used for radiation protection.

Effect of Testicular Histopathology on Pregnancy Outcomes in Non-Obstructive Azoospermia (비폐쇄성 무정자증 환자에서 고환의 조직병리학적 진단에 따른 체외수정시술 결과의 비교)

  • Park, Chan-Woo;Seo, Ju-Tae;Park, Yong-Seog;Kim, Hye-Ok;Yang, Kwang-Moon;Kim, Jin-Young;Koong, Mi-Kyoung;Kang, Inn-Soo;Song, In-Ok
    • Clinical and Experimental Reproductive Medicine
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    • v.35 no.4
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    • pp.293-301
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    • 2008
  • Objective: To evaluate outcomes of patients with non-obstructive azoospermia (NOA) undergoing the testicular sperm extraction (TESE) combined with intracytoplasmic sperm injection (ICSI) with different histopathologic subgroups. Method: A total of 122 embryo-transferred TESE/ICSI cycles were compared among NOA subgroups; Germ-cell aplasia (GA, 40 cycles), Maturation arrest (MA, 32 cycles) and severe hypospermatogenesis (S-HS, 50 cycles). Obstructive azoospermia (OA, 667 cycles) patients were served as a control. TESE/ICSI outcomes such as fertilization rate (FR), clinical pregnancy rate (CPR) and live birth rate (LBR) were evaluated. Results: The 2PN FR of embryo-transferred TESE/ICSI cycle was 58.1% in GA, 42.2% in MA and 48.0% in S-HS, which was significantly lower than that of OA (72.9 %, p<0.001). For ICSI-spermatozoa cycles, there were no significant differences in CPR (22.6%, 29.4% and 26.1%) and LBR (16.1%, 29.4% and 19.6%) among NOA subgroups. The CPR of ICSI-spermatid cycles was 0.0%, 9.1% and 0.0% without a live birth. For ICSI-spermatocyte cycles, no clinical pregnancies occurred in any group. Conclusion: There was no significant difference in the FR of embryo-transferred TESE/ICSI cycles among NOA subgroups. The FR among all NOA subgroups was significantly lower than that of OA. Testicular histopathology in NOA did not affect successful pregnancy if spermatozoa extraction from the testis is successful and embryo transfer is possible.

Clinical Utility of Bone Scan in the Diagnosis of Temporomandibular Disorders (측두하악장애의 진단에서 Bone Scan의 유용성)

  • Kim, In-Joo;Kang, Yang-Ho;Son, Seok-Man;Lee, Kyoung-Seog;Lee, Jae-Bok;Kim, Yong-Ki;Seo, Bong-Jik;Park, June-Sang;Ko, Myung-Yun;Son, Seong-Pyo
    • The Korean Journal of Nuclear Medicine
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    • v.29 no.4
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    • pp.511-517
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    • 1995
  • Bone scan is a very sensitive diagnostic imaging test for detecting bone and joint disorders. So it might be useful in the diagnosis of temporomandibular disorders of the joint origin. Thus, the effectiveness of bone scan for detecting temporomandibular joint(TMJ) diseases and differentiating the TMJ disc displacement from the TMJ arthritis was evaluated. Bone scan was done in 21 patients with TMJ disc displacement(13 unilaterally affected, 8 bilaterally affected), 25 patients with TMJ arthritis(23 unilateral, 3 bilateral), and 39 volunteers with no signs, symtoms, or history of TMJ disease. TMJ simple uptake rate(SUR) and difference of both TMJ SUR were calculated from the 100,000 count lateral image of head and neck region in 99mTc MDP bone scan. Transcranial and panorama X-ray examination was also done in all patients. TMJ SUR(%) were $1.673{\pm}0.606$ in TMJs affected with arthritis, $1350{\pm}0.351$ in TMJs affected with disc displacement, and $1.084{\pm}0.172$ in TMJs of controls. Significant differences were demonstrated among them(p<0.01) Difference of bith TMJ SUR was highest in patients with unilateral TMJ arthritis($0.608{\pm}$0.533, p<001), and there is no significant difference between that of controls and that of unilateral TMJ dist displacement patients($0.062{\pm}0.063$ vs $0.122{\pm}0.100$). TMJ SUR of Joint with bone change on X-ray finding was not significantly different from that of joint with normal X-ray finding. Those in patients with unilateral TMJ disc displacement(696% and 87% vs 23.1% and 23%). The proportions of patients with increased TMJ SUR and difference of both TMJ SUR(>mean+2SD of controls) in unilateral TMJ arthritis patients were significantly higher than those in patients with unilateral TMJ disc displacement(69.6% and 87% vs 23.1% and 23%). Conclusively, bone scan nay help to detect TMJ disease and differentiate TMJ disc displacement from TMJ arthritis.

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Reticuloendotheliosis (세망내피증)

  • 김순재
    • KOREAN POULTRY JOURNAL
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    • v.12 no.6 s.128
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    • pp.54-57
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    • 1980
  • 세망 내피증은 최근 알려지기 시작하고 있는 가금류에 종양을 일으키는 종양성 질병으로 그 증상이 백혈병과 마렉크병과 유사하여 감별진단이 어렵고 실험적으로 30$\%$정도의 폐사율을 가지고 있는 질병이다.

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