• Title/Summary/Keyword: 직접접합

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Failure Properties of Common Tendon Origins at the Human Elbow after Static and Repetitive Loading (정적 및 반복하중 시의 주관절 Tendon의 파괴 물성치 측정)

  • Han, Jeong-Su;Lee, Gwan-Hui;Yu, Jae-Yeong
    • Journal of Biomedical Engineering Research
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    • v.19 no.4
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    • pp.393-401
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    • 1998
  • Based on clinical observations, it is suspected that the bone-tendon origin is the site where piratical failure, leading to pathophysiological changes in the humeral epicondyle after repetitive loading, is initiated Mechanical properties and failure patterns of the common extensor and flexor tendons of the humeral epicondyle under static and repetitive loading have not been well documented. Our goal was to determine mechanical properties of failure strength and strain changes, to correlate strain changes and the number of cyclic repetitions, and to identify the failure pattern of bone-tendon specimens of common extensor and flexor tendons of the humeral epicondyle. Mechnaical properties of human cadaver bone-tendon specimens of the common extensor and flexor tendons of the humeral epicondyle were tested under two different loading rates. No statistically significant difference in ultimate tensile strength was found between male and female specimens or between slow (10 mm/sec) and fast elongation (100 mm/sec) rates. However, a statistically significant difference in ultimate tensile strength between the common extensor (1190.0 N/$cm^2{\pm}$388.8) and flexor 1922.0 N/$cm^2{\pm}$764.4)tendons was found (p<0.05). When loads of 25%, 33%, and 41% of the ultimate tensile strength of their contralateral sides were applied, the number of cycles required to reach 24% strain change for the common extersor and flexor tendons were approximately 8,893, 1,907, and 410, respectively. The relationship between cycles and loads was correlated ($R^2$=0.46) Histological observation showed that complete or partial failure after tensile or cyclic loadings occurred at the transitional zone, which is the uncalcified fibrocartilage zone between tendon and bone of the humeral epicondyle. Sequential histological sections revealed that failure initiated at the upper, medial aspect of the extensor carpi radialis brevis tendon origin. Biomechanical and hstological data obtained in this study indicated that the uncalcified fibrocartilage zone at the bone-tendon origin of the common extensor and flexor tendons is the weak anatomical structure of the humeral epicondyle.

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The Condition of Regeneration and Antibiotics Concentration for Gene Transformation of Zygotic Embryo in Panax ginseng C. A. Meyer (인삼(Panax ginseng C. A. Meyer)접합자 배의 형질전환을 위한 재분화 및 항생제 농도 조건)

  • 양덕춘;이은경;최원균;김무성
    • Korean Journal of Plant Resources
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    • v.16 no.1
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    • pp.74-81
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    • 2003
  • To obtain multi-shoot using zygotic embryos dissected from ginseng seed, the embryos were cultured on MS medium supplemented with CPA and BA. Effective multi-shoot induction was achieved on 0.5mg/ t CPA and 1.0mg/ t BA treatment. Among the various plant growth regulator treatment, MS basal medium with 1mg/ t 2,4-D and 0.5mg/ t kinetin was more competent and could be induced 4∼6 shoots per one embryo. Also, the best condition for pre-embryoid induction from ginseng cotyledon so as to ginseng transformation appeared to 1mg/ t 2,4-D and 0.5mg/ t kinetin treatment. The kanamycin level to select transformants varied greatly by different explant tyues. The petiole explants with leaf and embryo could survived up to 100$\mu\textrm{g}$ / ml kanamycin concentration where as petiole explants without leaf died all at the level. Conclusionally, our results suggest that optimum kanamycin concentration for ginseng transformation using somatic embryos is about 75∼100$\mu\textrm{g}$ / ml concentration.

Impacts of the High Resolution Land Cover Data on the 1989 East-Asian Summer Monsoon Circulation in a Regional Climate Model (지역기후모델에서 고해상도 지면피복이 1989년 동아시아 여름몬순 순환에 미치는 영향)

  • Suh, Myoung-Seok;Lee, Dong-Kyou
    • Atmosphere
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    • v.15 no.2
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    • pp.75-90
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    • 2005
  • This study examines the impacts of land cover changes on the East Asia summer monsoon with the National Center for Atmospheric Research Regional Climate Model (NCAR RegCM2), coupled with Biosphere Atmosphere Transfer Scheme (BATS). To assess the goals, two types of land cover maps were used in the simulation of summer climate. One type was NCAR land cover map (CTL) and the other was current land cover map derived from satellite data (land cover: LCV). Warm and cold surface temperature biases of $1-3^{\circ}C$ occurred over central China and Mongolia in CTL. The model produced excessive precipitation over northern land area but less over southern ocean of the model domain. Changes of biophysical parameters, such as albedo, minimum stomatal resistance and roughness length, due to the land cover changes resulted in the alteration of land-atmosphere interactions. Latent heat flux and wind speed in LCV increased noticeably over central China where deciduous broad leaf trees have been replaced by mixed farm and irrigated crop. As a result, the systematic warm biases over central China were greatly reduced in LCV. Strong cooling of central China decreased pressure gradient between East Asian continent and Pacific Ocean. The decreased pressure gradient suppressed the northward transport of moisture from south China and South China Sea. These changes reduced not only the excessive precipitation over north China and Mongolia but also less precipitation over south China. However, the land cover changes increased the precipitation over the Korean Peninsula and the Japan Islands, especially in July and August.

The signal property and structure design of CsI:Na/a-Se for diagnostic x-ray imaging (진단 X선 영상을 위한 CsI:Na/a-Se 구조설계 및 신호특성)

  • Park, Ji-Koon;Heo, Ye-Ji;Park, Jeong-Eun;Park, Sang-Jin;Kim, Hyun-Hee;No, Ci-Chul;Kang, Sang-Sik
    • Journal of the Korean Society of Radiology
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    • v.3 no.4
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    • pp.35-38
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    • 2009
  • Flat-panel x-ray detectors using a phosphor and photoconductor material have been used for application in various medical modalities. In this study, the monte carlo simulation, optical and x-ray response characteristics were investigated in the conversion structure obtained by a columnar CsI:Na scintillation layer with a photosensitive amorphous selenium layer. Firstly, from the measurement of luminescent spectrum of CsI:Na and absorption spectrum of a-Se layer, the signal conversion characteristics are analysed. And also, the x-ray sensitivity is measured and compared with conventional a-Se($500{\mu}m$) as a function of electrical field. From the experimental result, the x-ray sensitivities of the CsI:Na($180{\mu}m$)/a-Se($30{\mu}m$) detector and the a-Se($500{\mu}m$) detector were $7.31nC/mR-cm^{2}$ and $3.95nC/mR-cm^{2}$at an electric field of $10V/{\mu}m$, respectively.

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Construction of Research Fronts Using Factor Graph Model in the Biomedical Literature (팩터그래프 모델을 이용한 연구전선 구축: 생의학 분야 문헌을 기반으로)

  • Kim, Hea-Jin;Song, Min
    • Journal of the Korean Society for information Management
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    • v.34 no.1
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    • pp.177-195
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    • 2017
  • This study attempts to infer research fronts using factor graph model based on heterogeneous features. The model suggested by this study infers research fronts having documents with the potential to be cited multiple times in the future. To this end, the documents are represented by bibliographic, network, and content features. Bibliographic features contain bibliographic information such as the number of authors, the number of institutions to which the authors belong, proceedings, the number of keywords the authors provide, funds, the number of references, the number of pages, and the journal impact factor. Network features include degree centrality, betweenness, and closeness among the document network. Content features include keywords from the title and abstract using keyphrase extraction techniques. The model learns these features of a publication and infers whether the document would be an RF using sum-product algorithm and junction tree algorithm on a factor graph. We experimentally demonstrate that when predicting RFs, the FG predicted more densely connected documents than those predicted by RFs constructed using a traditional bibliometric approach. Our results also indicate that FG-predicted documents exhibit stronger degrees of centrality and betweenness among RFs.

A Study on the UCC Copyright which uses the Broadcasting Contents and the ODR(Online Dispute Resolution) through the Online Technical embodiment : Focusing on the CCl as the Conversational law Approach (방송콘텐츠를 이용한 UCC의 저작권 문제와 온라인 기술 구현을 통한 ODR(Online Dispute Resolution)의 가능성에 관한 연구 : Conversational Law 접근으로써 CCL을 중심으로)

  • Kim, Mi-Sun;Yu, Sae-Kyung
    • 한국HCI학회:학술대회논문집
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    • 2008.02b
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    • pp.558-564
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    • 2008
  • The study aims to examine the UCC (User Created Contents) Copyright which use the broadcasting contents. UCC are classified by UGC(User Generated Contents), UMC(User Modified Contents), and URC(User Recreated Contents). Especially UMC and URC correspond to a problem of copyright. Following the Copyright Protection Center investigation in 2006, it reported that 83.7% UCC are infringement of copyright. In spite of remarkable the UCC copyright problem, the concrete resolution does not exist. Also it is difficult to apply the offline legal conformity because of online nature of the UCC. The study observes the UCC copyright dispute instances which use the broadcasting contents and investigates a resolution of the UCC copyright. Considering the online media nature, it tries to analyse CCL(Creative Common License) as the ODR(online Dispute Resolution). It is meaningful to search the possibility of UCC copyright problem through the online technical embodiment.

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Study on Improvement of Signal to Noise Ratio for HgI2 Radiation Conversion Sensor Using Blocking Layer (Blocking layer 적용을 통한 HgI2 방사선 변환센서의 신호대 잡음비 향상에 관한 연구)

  • Park, Ji-Koon;Yoon, In-Chan;Choi, Su-Rim;Yoon, Ju-Sun;Lee, Young-Kyu;Kang, Sang-Sik
    • Journal of the Korean Society of Radiology
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    • v.5 no.2
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    • pp.97-101
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    • 2011
  • In this study, the basic research verifying possibility of applications as radiology image sensor in Digital Radiography was performed, the radiology image sensor was fabricated using double layer technique tio decrease dark current. High efficiency material in substitution for a-Se have been studied as a direct method of imaging detector in Digital Radiography to decrease dark current by using Hetero junction already used as solar cell, semiconductor. Particle-In-Binder method is used to fabricate radiology image sensor because it has a lot of advantages such as fabrication convenient, high yield, suitability for large area sensor. But high leakage current is one of main problem in PIB method. To make up for the weak points, double layer technique is used, and it is considered that high efficient digital radiation sensor can be fabricated with easy and convenient process. In this study, electrical properties such as leakage current, sensitivity is measured to evaluate double layer radiation sensor material.

A Study on Planning Open Space between Civic Buildings as an Active Place (적극적 장소로서의 도심의 건물 외부 오픈 스페이스 환경 계획에 관한 연구)

  • 김혜원
    • Archives of design research
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    • v.14
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    • pp.141-150
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    • 1996
  • In recent years space planning for modern city has been accomplished through scientific high technique and computer supported collaborative work. Relatively human being is treated as a component of the space or whole building and according to the social structure people tend to prefer private space. The necessity of the open space as an active place is emphasized now because the interaction created between users of the space and the nature, surrounding environment can influence on improving quality of outdoor life and giving the place specific identity. In this paper three ways of analyses of components which compose the open space are studied. Especially through the process of analyses derived from differenet areas, the necessity of communication model in collaborative work is proposed.

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A Case of Neonatal Intrahepatic Cholestasis Caused by Citrin Deficiency (NICCD) Confirmed by SLC25A13 Mutation

  • Son, Yeong-Bae;Jang, Ju-Yeong;Park, Hyeong-Du;Lee, Su-Yeon
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.14 no.2
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    • pp.186-190
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    • 2014
  • Citrullinemia type 2 (citrin deficiency) is an autosomal recessive inborn error metabolism, caused by the SLC25A13 gene mutation. Citrin deficiency is associated with two clinical phenotype; neonatal-onset type II citrullinemia (CTLN2), also known as neonatal intraphepatic cholestasis caused by citrin deficiency (NICCD) and adult-onset CTLN2. Clinical manifestations of NICCD include poor growth, intrahepatic cholestasis, liver dysfunction and increased plasma citrulline, methionine, threonine, arginine. The molecular diagnosis could be confirmed by SLC25A13 gene mutation analysis. A 3-month-old male infant with persistent jaundice was referred for evaluation. Newborn screening was normal at birth. Mild elevation of serum ammonia and AST/ALT were observed. Plasma amino acid analysis showed significantly elevated citrulline, methionine, threonine. DNA sequence analysis of the SLC25A13 gene revealed two compound heterozygous mutations, c.[852_855del]($p.Met285Profs^*2$) and [1180+1G>A]. We suggest that NICCD should be considered as one of the cause of in infants with cholestatic jaundice, although the newborn screening was normal.

Thermal Compression of Copper-to-Copper Direct Bonding by Copper films Electrodeposited at Low Temperature and High Current Density (저온 및 고전류밀도 조건에서 전기도금된 구리 박막 간의 열-압착 직접 접합)

  • Lee, Chae-Rin;Lee, Jin-Hyeon;Park, Gi-Mun;Yu, Bong-Yeong
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2018.06a
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    • pp.102-102
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    • 2018
  • Electronic industry had required the finer size and the higher performance of the device. Therefore, 3-D die stacking technology such as TSV (through silicon via) and micro-bump had been used. Moreover, by the development of the 3-D die stacking technology, 3-D structure such as chip to chip (c2c) and chip to wafer (c2w) had become practicable. These technologies led to the appearance of HBM (high bandwidth memory). HBM was type of the memory, which is composed of several stacked layers of the memory chips. Each memory chips were connected by TSV and micro-bump. Thus, HBM had lower RC delay and higher performance of data processing than the conventional memory. Moreover, due to the development of the IT industry such as, AI (artificial intelligence), IOT (internet of things), and VR (virtual reality), the lower pitch size and the higher density were required to micro-electronics. Particularly, to obtain the fine pitch, some of the method such as copper pillar, nickel diffusion barrier, and tin-silver or tin-silver-copper based bump had been utillized. TCB (thermal compression bonding) and reflow process (thermal aging) were conventional method to bond between tin-silver or tin-silver-copper caps in the temperature range of 200 to 300 degrees. However, because of tin overflow which caused by higher operating temperature than melting point of Tin ($232^{\circ}C$), there would be the danger of bump bridge failure in fine-pitch bonding. Furthermore, regulating the phase of IMC (intermetallic compound) which was located between nickel diffusion barrier and bump, had a lot of problems. For example, an excess of kirkendall void which provides site of brittle fracture occurs at IMC layer after reflow process. The essential solution to reduce the difficulty of bump bonding process is copper to copper direct bonding below $300^{\circ}C$. In this study, in order to improve the problem of bump bonding process, copper to copper direct bonding was performed below $300^{\circ}C$. The driving force of bonding was the self-annealing properties of electrodeposited Cu with high defect density. The self-annealing property originated in high defect density and non-equilibrium grain boundaries at the triple junction. The electrodeposited Cu at high current density and low bath temperature was fabricated by electroplating on copper deposited silicon wafer. The copper-copper bonding experiments was conducted using thermal pressing machine. The condition of investigation such as thermal parameter and pressure parameter were varied to acquire proper bonded specimens. The bonded interface was characterized by SEM (scanning electron microscope) and OM (optical microscope). The density of grain boundary and defects were examined by TEM (transmission electron microscopy).

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