• Radiation Oncology Journal
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• 제26권4호
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• pp.213-221
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• 2008

목 적: 직장암에 수술 전 항암화학요법과 방사선치료를 동시에 병용시행한 후 완치절제술 후 병리학적 완전관해율과 종양 병기 하향률에 영향을 주는 예측인자를 후향적으로 분석하여 환자에 따른 맞춤치료의 가능성을 알기 위하여 본 연구를 시도하였다. 대상 및 방법: 2000년 5월부터 2008년 3월까지 국소적으로 진행된 직장암으로 진단받고 원격전이가 없는 환자 39명을 대상으로 수술 전 항암화학요법과 골반강에 방사선치료 50.4 Gy ($45{\sim}59.4\;Gy$)를 시행한 후 완치적 수술후 절제된 조직을 병리학적으로 관찰하여 완전관해율과 종양 및 림프절의 병기하향률을 측정하였다. 항암화학요법은 39명 중 38명은 방사선치료 1주와 5주에 각각 1주간 5-fluorouracil과 leucovorin을 연속적으로 정맥 주입하였으며 1명은 방사선치료기간 중 하루에 2회 capecitabine를 복용하였다. 결 과: 병리학적 완전관해를 보인 환자는 39명 중 12명(31%), 종양-병기하향을 보인 환자는 24명(63%)이었으며 임상적으로 림프절이 양성인 환자 28명 중 12명은(43%) 병리학적으로 하향되었으며 2명은 임상적으로 림프절이 음성이었으나 병리학적으로 양성을 보였다. 단변량분석에 의하면 종양의 둘레범위가 직장의 50% 미만(p=0.031), 종양의 길이가 5 cm 미만(p=0.004), 치료 후 CEA 수치가 3.0 mg/mL 이하(p=0.015)인 환자에서 병리학적 완전관해율이 높았다. 또한 선암(p=0.045), 방사선량이 50 Gy 이상(p=0.021)인 환자에서 병기-하향률이 높았고, 방사선 치료 기간이 42일 이하인(p=0.018)환자에서 림프절-병기하향률이 높았다. 다변량분석에 의하면 종양의 둘레범위가 50% 미만(HR 0.150; p=0.028), 종양의 길이가 5 cm 미만인(HR 0.084; p=0.005) 환자에서 통계학적으로 유의하게 병리학적 완전관해율이 높았으며, 방사선량이 50 Gy 이상 높은 경우(HR 0.115; p=0.025) 종양-병기하향률이 높았고 방사선치료 기간이 42일 이하인(HR 0.028; p=0.010) 경우 림프절-병기하향률이 높았다. 병리학적 완전관해에 영향을 주는 예측인자는 종양의 둘레범위와 종양의 길이이었으며, 종양-병리하향에 영향을 주는 예측인자는 방사선량, 림프절-병기하향에 영향을 주는 예측인자는 방사선치료 기간이었다. 이러한 예측인자를 파악함으로써 환자의 치료결과를 예측할 수 있으며 위험인자가 있는 환자에 좀 더 적극적인 치료계획을 설정하는 데 도움이 될 것으로 생각한다.

• 동의생리병리학회지
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• 제25권6호
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• pp.1119-1128
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• 2011

The aim of this study is to collect and analyze clinical studies on acupuncture therapies of Post-stroke depression, and to suggest a method on study about acupuncture therapies. In this thesis, electronic searches were performed. Also, 6 major journals associated with oriental medicine in Korea were searched manually. Through searching, 27 studies were selected and analyzed. There were 24 controlled studies and 3 non-controlled studies. Treatment methods were acupuncture, electronic-acupuncture, eye-acupuncture, abdominal-acupuncture and pharmaco-puncture. The percentages of these treatment method were 59.2%, 29.6%, 3.7%, 3.7% and 3.7%, respectively. Acupuncture points such as GV20, PC6, ST36, SP6, LV3, GV24, GV26, LI14, LI11, H7, ST40, GB20, GB34 and LI15 were used. In comparison of results before and after acupuncture treatment, there were statistically significant improvement in 26 studies. Based on the results from above, the studies on acupuncture for Post-stroke depression needs to be standardized and more appropriate high-quality study models should be introduced.

• 대한한방내과학회지
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• 제38권2호
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• pp.195-200
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• 2017

Objectives: The purpose of this case report is to describe the effect of Korean medicine therapy on patients with tension-type headaches. Methods: This study consisted of four patients with tension-type headaches. The patients were treated with Korean medicine therapies, such as herbal medicine (Gunoe-tang), acupuncture, and cupping, in addition to physical therapy. None of the patients took any analgesics during the admission period. To evaluate the effects of the treatment, the Numeric Rating Scale (NRS) for headaches was used. Results: After the treatment, the patients' complaints decreased, as shown by the results of the NRS. Conclusion: Treatment with Korean medicine may ameliorate tension-type headaches.

• 대한한의학방제학회지
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• 제28권4호
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• pp.443-450
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• 2020

Objectives : The aim of this study is to evaluate the long-term effect of Jeongjeongamiijin-tang-gamibang by measuring the symptom-free-period after treatment through sensory and subjective evaluation. Methods : We administered Jeongjeongamiijin-tang-gamibang to 10 patients diagnosed with stomach heat pattern. The asymptomatic period was measured from the end of treatment by sensory and subjective evaluation. Results : The total dose of medication administered to the patients was dose of 3 to 7 months and the mean was 4.1 months. Symptom-free period from the end of treatment was 24.5 to 69.4months, and the mean of treatment was 46.97 months. Conclusions : Jeongjeongamiijintanggamibang is effective for the treatment of halitosis and its effect is sustained for a long time.

• 대한한방소아과학회지
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• 제26권1호
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• pp.46-59
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• 2012

Objectives The purpose of this study is to investigate recent clinical studies on effect of acupuncture for rhinitis in other countries. We have analyzed the studies on effect of acupuncture for rhinitis within randomized controlled trial(RCT), reviewed for 11 years (from 2001 to 2011). Methods The search database includes PubMed. To narrow the search, the following key search terms were used: 'rhinitis, acupuncture'. The search was limited to the publication date from 2001 to 2011. Results Total 20 studies were selected: RCT(13), review(5), case report(1), and cost effectiveness study(1). In RCT, 9 studies used acupuncture only, and 8 studies of them have revealed that acupuncture is effective on rhinitis. In review, 3 studies are systematic review, 2 studies are no systematic review. Among systematic review, 2 studies have revealed partial effectiveness of acupuncture for rhinitis, but they suggested the necessity of further studies. Conclusions Domestic studies on effect of acupuncture for rhinitis are necessary. For more accurate results, controlled, large scale and well designed studies are recommended.

• The Journal of Korean Physical Therapy
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• 제19권5호
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• pp.11-19
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• 2007

Purpose: The purpose of this study was to examine effect of trunk control using pelvic movements upon the foot pressure in patients with hemiplegia. Methods: Twelve males with hemiplegia were the procedure executed turnk control using pelvic movements. The foot pressure were measured using Parotec-system. Results: The data were analysed with paired t-test. First, there was a significant increase in external and internal sensors of dynamic foot pressure change of the hindfoot before and after therapy. Also there was significant increase in hallux (p<0.05). Second, there was a significant increase of affected side in support phase(p<0.05) and decreased of affected side in overlapping phase(p<0.05). Third, there was a significant increase in foot floor contact time and impulse pressure rate between affected and non affected side(p<0.05). Conclusion: The trunk control with pelvic movement had an significant effect on the legs by increase activities of hip flexors and abductors. Also had an effect on ankle dorsiflexion and plantar flexor by biomechanical movement.

• 한국임상수의학회지
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• 제25권4호
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• pp.289-291
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• 2008

한국으로 이주한 3년령의 암컷 핏불테리어가 엘리키아 증으로 진단되었다. 혈액검사상 중등도의 빈혈, 미약한 혈소판감소증과 고단백혈증, 고글로불린혈증을 보였다. 혈청검사에서 엘리키아 키트에 양성이었으며, 면역형광 항체법에 의한 항체가는 1:10240 이었다. 백혈구 연층 도말상에서는 엘리키아 감염체가 관찰되지 않았고 말초혈액을 이용하여 PCR 검사를 하였으나 음성이었다. 환자는 doxycycline에 잘 반응하였으며 치료 후 건강을 회복하였다.

• 대한소아치과학회지
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• 제47권4호
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• pp.463-468
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• 2020

유표피낭종은 구강 내에서 드물게 보이는 양성병소이며 선천적 혹은 후천적으로 발생할 수 있다. 이 병소는 대개 느리게 자라는 낭종으로, 저작이나 발음을 방해 할 정도로 크기가 커지거나 2차 감염이 발생하기 전 까지는 주로 무증상을 보인다. 따라서 진단이 지연되는 경우가 많으며, 신생아나 영유아에서 진단되는 경우는 매우 드문 병소이다. 유표피낭종은 대부분 구강저에서 발생하며 상순에서의 발생은 드물다. 이 증례에서는 29개월 환아의 상순 내측 점막에서 촉진되는 종물을 구강 내 접근법을 이용하여 외과적으로 적출하고, 조직 병리학적으로 유표피 낭종으로 진단하였기에 보고하는 바이다.

• Pediatric Infection and Vaccine
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• 제20권1호
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• pp.36-40
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• 2013

간농양은 선진국과 개발도상국에서 발생빈도에 차이가 있는 질환으로 국내에서는 드물다. 면역결핍, 간, 담도계기형, 천공성 충수염, 외상, 단백질 결핍 등의 선행요인이 있을 때 발생하기 쉬우며 Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Enterococcus, Bacteroides와 Entamoeba histolytica 등에 의해 유발된다. 저자들은 발열을 주소로 내원한 건강한 12세 남아에서 컴퓨터 단층촬영을 시행하여 간농양을 발견하였으며 경피배액술 흡인물 배양 검사에서 Staphylococcus epidermidis가 검출되어 항생제를 투여하여 합병증 없이 치료하였기에 보고한다.

• The Journal of Korean Physical Therapy
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• 제21권2호
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• pp.9-14
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• 2009

Purpose: This study examined the effect of constraint-induced movement therapy (CIMT) on improving the hand function in hemiplegic side. Methods: Ten subjects without a control group were given CIMT to the hemiplegic side for 3 weeks. The effects of their hand function and sensibility were examined using a MAL and two point discrimination test. Repeated ANOVA was carried out for an analysis of the effects of the application of CIMT before and after treatment. Results: The participants showed significant improvement in their functional aspect with CIMT while there were no significant changes in the time domain variables. There was significant improvement in the quantitative and qualitative aspect of MAL, as well as significant improvement in the two-point discrimination function in all fingers. Conclusion: CIMT can enhance the motor function and sensory function of the hand in hemiplegic patients.