• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2002.10a
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• pp.160-160
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• 2002

호소 수질에 영향을 미치는 대표적 인자로 외부 유입물질과 퇴적물을 들 수 있다. 따라서, 호소 수질 관리를 위해서는 호소로 유입되는 점ㆍ비점 오염원 관리와 함께, 퇴적층 관리도 수반되어야만 한다. 특히, 호소수가 주요 식수원으로 사용되는 경우에는 엄격한 퇴적토질 평가가 이루어져야 할 것이다. 본 연구에서는 소양호 퇴적층에 대한 환경지질학적 조사 연구의 일환으로 다양한 bioassays 기법(the battery of bioassays)을 적용하여 퇴적토의 오염상태를 평가하였다.

• Bulletin of Food Technology
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• v.14 no.3
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• pp.3-16
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• 2001

대두에 함유되어 있는 생리활성 성분에 대한 과학적 규명에 뒤이어 몇 년 전 부터 대두와 인체생리와 관련한 여러 임상 데이터들과 대사시험에 관한 연구가 최근 집중적으로 수행되고 있다. 대두의 이소플라본은 특히 여성의 유방암, 남성의 전립선 암 등 성호르몬 관련 질환에 탁월한 효과가 있고 폐경과 관련된 호르몬 치료요법의 대체 수단으로 활발한 연구가 진행되고 있다. 그중 본문에서는 식이요인이 질병예방에 매우 중요한 인자로 작용하는 분야인 체내 지질대사 개선 및 유방암 예방과 관련된 최근 연구내용을소개한다.

• Journal of Life Science
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• v.4 no.3
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• pp.102-112
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• 1994

알콜성 간장해의 발생, 진전에는 많은 인자가 관여하고 있으며 극히 복잡한 병태를 형성하는데 그 기전으로는 1)간내 [NADH]/[NAD] 비의 상승, 2)에탄올의 주 대사산물인 아세트알데히드에 의한 간장해, 3)면역기구에 의한 간장해, 4)과산화지질, 활성산소 및 free radical 에 의한 장해와 5) 중심정맥역의 hypoxia에 의한 간세포장해 기전을 들 수 있다. 본 총설에서는 알콜을 장기 섭취할 경우 간에서의 대사경로와 현재 고려되고 있는 몇 가지 알콜성 간장해 발생기전에 대한 최근의 연구들을 정리하였다.

• Economic and Environmental Geology
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• v.50 no.6
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• pp.423-433
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• 2017

Korea Institute of Geoscience and Mineral Resources and Department of Geological Survey and Mineral Exploration in Myanmar have explored the Kalaymyo chromitite deposit, Myanmar since 2013. It is now necessary to find a geochemical indicator for efficient mineral exploration in the future and building a 3D geological model for this ore deposit. Mantle podiform chromitite is a major type of Cr ore in this region, which is considered to be formed by mantle-melt interaction beneath the mantle-crust boundary of oceanic lithosphere. In this study we measured major element composition of spinels in harzburgite, dunite and chromitite, and examined the hypothesis that spinel Cr#(molar Cr/(Cr+Al)${\times}$100) can be used as a geochemical indicator in exploration for the Kalaymyo chromitite. The results show that there is a clear correlation between spinel Cr# and distribution of chromitite. The spinel Cr# of harzburgite increases with decreasing the distance from the chromitite bodies. The spinel composition is also closely associated with texture and occurrence of spinels. The high Cr# spinels (30-48) are subhedral to euhedral and enclosed by olivine whereas the low Cr# spinels (16-27) are anhedral and commonly associated with pyroxenes. Often the low Cr# spinels show symplectite intergrowths with pyroxenes, indicating their residual nature. These petrological and geochemical results suggest that the high Cr# spinels have resulted from mantle-melt interaction. We suggest that spinel Cr# can be used as a geochemical indicator for Cr ore exploration and as one of critical factors in 3D geological model in the Kalaymyo chromitite deposit.

• Biomedical Science Letters
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• v.6 no.4
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• pp.237-244
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• 2000

It has been reported that plasma membrane activity of the spermatozoa may be susceptible to be influenced by extracellular osmolality and such membranous changes involve infracellular molecular changes, special regard to the structure of membranous lipids, and the accompanying ion-channel of which are closely related with their fluidity of $Ca^{2+}$ and HCO$^{-}_{3}$. It is of common recognition that a certain kind of sterol acceptor player an important to induce lipid fluctuation of the sperm plasma membrane which have been influenced by BSA administration and came in effect to outflow of cholesterol from the spermatozoa and resulted in changes of ionic fluidity to facilitate adenylyl cyclase, and to induce protein tyrosine phosphorylation by increase of cAMP and activation of PKA. Thus it seems likely that an augmentation of the acrosomal reaction is closely related with protein tyrosine phosphorylation. The following experimental results were obtained in the present study; Under the high osmolality conditions, the spermatozoa motility declined significantly and the structural change of the plasma membrane diminished to confirm that the response degrees to the osmolality depended upon the water transfer volume through the plasma membrane and the changes of cellular volume. Those experimental results suggest that a physiological parameter such as low temperature condition played an important role for presentation of spermatozoa and that inducement of spermatozoa activation for reinforcement of protein tyrosine phosphorylation. On the other hand, it seemed likely that the BSA administration as one of sterol accepters might represent a key role also under the high osmolality condition and their result also suggests that osmolality change, special regard to high osmolality condition may play an important role also in the processes of signal transmission.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.6
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• pp.899-905
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• 2003

The effects of cooked soybean and a traditional fermented soy product, chongkukjang, on blood pressure and lipid metabolism were studied in spontaneously hypertensive rat (SHR). SHRs were divided into 3 groups (n=10, male), and fed casein, powders of cooked soybean, and chongkukjang as dietary protein sources for 6 weeks. Body weight gain was not different among experimental groups, but food efficiency was increased in groups fed cooked soybean and chongkukjang diets compared to control group. Consumption of cooked soybean and chongkukjang for 6 weeks in SHR significantly suppressed blood pressure rise with aging (p<0.05). Feeding of cooked soybean and chongkukjang to SHR decreased plasma triacylglycerols (p<0.05) by 21.6% and 30.2% and LDL-cholesterol by 30.0% and 27.5%, respectively. Addition of cooked soybean and chongkukjang to the diet resulted in reduction of total lipids and triacylglycerols of liver, while consumption of cooked soybean and chongkukjang resulted in the increase of fecal cholesterol and bile acid excretions, respectively (p<0.05). Cooked soybean and chongkukjang diets down-regulated the activity of hepatic HMG-CoA reductase by 56.4% and 94.5%, compared to control, respectively. From the above-mentioned results, it can be concluded that consumption of cooked soybean and chongkukjang might be helpful in preventing cardiovascular disease by suppressing blood pressure rise and hyperlipidemia.

• Korean Journal of Remote Sensing
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• v.35 no.2
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• pp.299-316
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• 2019

The purpose of this study was to analyze landslide susceptibility in the Pyeongchang area using Weight of Evidence (WOE) and Evidential Belief Function (EBF) as probability models and Artificial Neural Networks (ANN) as a machine learning model in a geographic information system (GIS). This study examined the widespread shallow landslides triggered by heavy rainfall during Typhoon Ewiniar in 2006, which caused serious property damage and significant loss of life. For the landslide susceptibility mapping, 3,955 landslide occurrences were detected using aerial photographs, and environmental spatial data such as terrain, geology, soil, forest, and land use were collected and constructed in a spatial database. Seventeen factors that could affect landsliding were extracted from the spatial database. All landslides were randomly separated into two datasets, a training set (50%) and validation set (50%), to establish and validate the EBF, WOE, and ANN models. According to the validation results of the area under the curve (AUC) method, the accuracy was 74.73%, 75.03%, and 70.87% for WOE, EBF, and ANN, respectively. The EBF model had the highest accuracy. However, all models had predictive accuracy exceeding 70%, the level that is effective for landslide susceptibility mapping. These models can be applied to predict landslide susceptibility in an area where landslides have not occurred previously based on the relationships between landslide and environmental factors. This susceptibility map can help reduce landslide risk, provide guidance for policy and land use development, and save time and expense for landslide hazard prevention. In the future, more generalized models should be developed by applying landslide susceptibility mapping in various areas.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.628-628
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• 2015

유역의 형상은 강우, 산사태 등과 같은 지배적인 침식작용과 더불어 지형 지질학적 요인들에 의해 결정되어 진다. 그러므로 유역형상에 대한 공간특성 분석을 위해서는 지형학적 요인과 다양한 침식작용에 대한 분석이 필요하다. 국내 외 많은 연구결과에 의하면 지형학적 인자에 의한 침식 형태는 국부경사와 집수면적의 크기에 의해 다양한 구간으로 나뉘며, 그 특성에 따라 지표침식, 세굴, 산사태 등으로 구분되는 것으로 연구된 바 있다. 일례로 유역 내 세굴과 관련된 지배인자는 집수면적보다는 국부경사에 반대로 지표침식, 산사태는 국부경사보다는 집수면적의 크기에 따라 영향을 받는다. 따라서 지형학적 인자(국부경사, 집수면적)의 임계치(threshold) 산출을 통해 침식특성(불안정지역)을 검토할 수 있으며, 이에 대한 물리적 검증은 여러 연구를 통해 물질플럭스(유량, 에너지)에 대한 Power Law로써 검증된바 있다. 본 연구에서는 이러한 지형학적 침식특성 분석을 위하여 2006년 집중호우에 의해 광역적 산사태가 발생한 강원도 평창군 진부면 일대의 $10m{\times}10m$ DEM로부터 국부경사, 집수면적을 산출하고 경사-면적한계곡선(Slope-Area Threshold Curve, SATC), 배수면적 확률분포곡선(Probability distribution of Drain Areas Curve, PDAC), 에너지지수 확률분포곡선(Probability distribution of Energy Index Curve, PEIC)를 실제 산사태지점과 중첩하여 도시하였다. 그 결과, 특정 임계구간(Threshold Area, Unstable area, 2~3권역)내에서 산사태 발생지점이 분포하는 것으로 분석되었다. 이를 통해 지형학적 인자만을 고려하여 미계측 유역에 대한 잠재적 불안정지역의 판별이 가능할 것으로 판단되며, 추후 광역적 사면안정해석에 적용 가능할 것으로 판단된다.

• The Journal of Engineering Geology
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• v.19 no.2
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• pp.177-189
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• 2009

The shear strength has been managed as an important factor in soil mechanics. The shear strength estimation model was developed to evaluate the shear strength using only a few soil properties by the linear regression analysis model which is one of the statistical methods. The shear strength is divided into two part; one is the internal friction angle (${\phi}$) and the other is the cohesion (c). Therefore, some valid soil factors among the results of soil tests are selected through the correlation analysis using SPSS and then the model are formulated by the linear regression analysis based on the relationship between factors. Also, the developed model is compared with the result of direct shear test to prove the rationality of model. As the results of analysis about relationship between soil properties and shear strength, the internal friction angle is highly influenced by the void ratio and the dry unit weight and the cohesion is mainly influenced by the void ratio, the dry unit weight and the plastic index. Meanwhile, the shear strength estimated by the developed model is similar with that of the direct shear test. Therefore, the developed model may be used to estimate the shear strength of soils in the same condition of study area.

• The Journal of Engineering Geology
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• v.18 no.1
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• pp.27-36
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• 2008

To derive easily the coefficient of permeability from several other soil properties, the estimation model of coefficient of permeability was proposed using linear regression analysis. The coefficient of permeability is one of the major factors to evaluate the soil characteristics. The study area is located in Kangwon-do Pyeongchang-gun Jinbu-Myeon. Soil samples of 45 spots were taken from the study area and various soil tests were carried out in laboratory. After selecting the soil factor influenced by the coefficient of permeability through the correlation analysis, the estimation model of coefficient of permeability was developed using the linear regression analysis between the selected soil factor and the coefficient of permeability from permeability test. Also, the estimation model of coefficient of permeability was compared with the results from permeability test and empirical equation, and the suitability of proposed model was proved. As the result of correlation analysis between various soil factors and the coefficient of permeability using SPSS(statistical package for the social sciences), the largest influence factor of coefficient of permeability were the effective grain size, porosity and dry unit weight. The coefficient of permeability calculated from the proposed model was similar to that resulted from permeability test. Therefore, the proposed model can be used in case of estimating the coefficient of permeability at the same soil condition like study area.