• Title/Summary/Keyword: 지모

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Selection of Oriental Medicinal Plants for Screening of Anticancer Agents (항암소재의 발굴을 위한 한방소재의 선별)

  • Park, Keun-Hyoung;Kim, So-Young;Chae, Hee-Jeong
    • KSBB Journal
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    • v.22 no.3
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    • pp.139-145
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    • 2007
  • An oriental medicinal database was used from medicinal plants for screening of anticancer agents. The prescription frequency and dosage of medicinal plats in 170 anticancer prescriptions were analyzed. From the total prescription score of each medical plant, it was found that high-scored medicinal plants have been widely studied in the previous research on the cancer treatment. Consequently, dangui, hwangui, banha, bachul, jinpy, insam, bacjakyak, deahwang, chungoong, jimo, chunnamsung, omija, hyunggae, huekchook, banggi, boclyung, osooyou were selected as raw materials for the screening of anticancer agents.

Anti-oxidant Effects of Anemarrhenae Rhizoma in Three Different Lineages (지모(知母) 추출물이 MCF-7 세포의 생존율에 미치는 영향)

  • Kim, Hyung-Woo;Kim, Bu-Yeo;Cho, Su-Jin;Cho, Su-In
    • The Journal of Internal Korean Medicine
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    • v.28 no.3
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    • pp.608-614
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    • 2007
  • Objectives : This study was carried out to investigate anti-proliferative effects on MCF-7 human breast cancer cells of Anemarrhenae Rhizoma (AR) extract. Breast cancer is the most common disease in Korean women. Despite remarkable improvements in treatment strategies against various cancers during the past 40 years. breast cancer still remains as one of the main causes of cancer mortality among women the whole world over. Methods : Be investigated the effects of AR on cytotoxicity of MCF-7 human breast cancer cells in various extract conditions (n-hexane, ethyl acetate, butanol and water fraction). Results : The extract of Anemarrhenae Rhjzoma inhibits the proliferation of MCF-7 cells in a dose dependent manner. Especially. the ethyl acetate fraction of Anemarrhenae Rhizoma showed specific Cytotoxicity on MCF-7 cells. Conclusions : In conclusion. it can be concluded that Anemarrhenae Rhizoma extract has an anti-proliferative effect on MCF-7 human breast cancer cells. Especially. the ethyl acetate fraction is most effective to inhibit proliferation of MCF-7 cells.

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Investigation of Antidiabetic Medicinal Plants using an Oriental Medicinal Database (동양의학 데이터베이스를 이용한 당뇨병에 효능을 가진 생약재의 탐색)

  • Kim, Dong-Hyun;Kang, Young-Gu;Kim, Hong;Chae, Hee-Jung
    • KSBB Journal
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    • v.19 no.2
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    • pp.125-131
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    • 2004
  • Various medicinal plants were examined as resources for antidiabetic biomaterials, using an oriental medicinal database. The prescription frequency and dosage of medicinal plants in 131 antidiabetic prescriptions were analyzed. Total prescription score of each medical plant was summed up from prescription table and score table. High-scored medicinal plants have been widely studied in the previous research on the diabetic treatment. Consequently, dangui, hwangryun, maekmoondong, ginseng, chick, saengjihwang, omija, bokryung, Jimo and cheonhwaboon were assumed to have high antidiabetic activities.

Studies on Efficacy of Crude Drug by Processing (II): Sedative Action, Prolonged Effect of Sleeping Time and Effects on Ileum-Smooth Muscle of Anemarrhenae Rhizoma (생약의 수치(修治)에 따른 약호연구(제2보) : 지모(知母)의 진정, 수면효과 및 장관평활근에 미치는 영향)

  • Sul, Soo-Young;Cho, Young-Whan;Rho, Young-Soo;Hong, Nam-Doo;Kim, Sin-Kyu
    • Journal of Pharmaceutical Investigation
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    • v.16 no.1
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    • pp.18-23
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    • 1986
  • Anemarrhenae Rhizoma has been clinically used as a sedative drug in oriental medicine. We observed the sedative action and effect on the movement of isolated-ileum with each water extract of Anemarrhenae Rhizoma (F-I), saline solution treated preparation (F-II) and 25% ethanol treated preparation (F-III). The results obtained were summerized as follows; 1) Sedative actions were recognized with F-I, F-II and F-III. 2) Prolonged effect of sleeping time was recognized significantly with F-I, F-II and F-III. 3) Each fraction of Anemarrhenae Rhizoma showed the released action on the isolated-ileum of the mouse, rat, rabbit and guinea pig, and antagonic action against contraction induced by acetylcholine, barium chloride and histamine. Thus the mechanism in the released action of the smooth muscle was partly considered as the direct dependence of the smooth muscle.

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Women's Empowerment in Making Health Care Decisions in Ethiopia (에티오피아 여성의 권한 부여 정도가 건강 관리 결정에 미치는 영향)

  • Azimova, Gulzhan;Park, Sang Chan
    • Journal of Korean Society for Quality Management
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    • v.46 no.4
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    • pp.1029-1042
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    • 2018
  • Purpose: The purpose of this study is to explore the health care decision making of Ethiopian women at household level. Moreover it is to understand the factors that influence to potential customers in healthcare industry from the social quality level perspective. Methods: We used Ethiopia Demographic Health Survey (EDHS) 2005 & 2016, which provided data about currently married women aged 15-49 years (N=2003, N=2017, respectively). We performed a chi-square test, and a Pearson correlation and a logistic regression. Andersen model is considered as well. Results: This study revealed that the mobility decision making has an association with health care decision making of women. Furthermore, there is a moderate effect of an economic decision making of women. Lastly, the women's decision making empowerment level increase year by year. Conclusion: Health care industry has to consider potential costumers among women like in Ethiopia, whose decision making empowerment will enhance on their own healthcare in future. It is very important to figure out factors from the social quality management domain. It helps finding a new market from downstream approach. From this point, the impact of decision making of women empowerment has a significant implication from the holistic perspective.

Morpho-GAN: Unsupervised Learning of Data with High Morphology using Generative Adversarial Networks (Morpho-GAN: Generative Adversarial Networks를 사용하여 높은 형태론 데이터에 대한 비지도학습)

  • Abduazimov, Azamat;Jo, GeunSik
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2020.01a
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    • pp.11-14
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    • 2020
  • The importance of data in the development of deep learning is very high. Data with high morphological features are usually utilized in the domains where careful lens calibrations are needed by a human to capture those data. Synthesis of high morphological data for that domain can be a great asset to improve the classification accuracy of systems in the field. Unsupervised learning can be employed for this task. Generating photo-realistic objects of interest has been massively studied after Generative Adversarial Network (GAN) was introduced. In this paper, we propose Morpho-GAN, a method that unifies several GAN techniques to generate quality data of high morphology. Our method introduces a new suitable training objective in the discriminator of GAN to synthesize images that follow the distribution of the original dataset. The results demonstrate that the proposed method can generate plausible data as good as other modern baseline models while taking a less complex during training.

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Responses of Artificial Flow-Sensitive Hair for Raider Detection via Bio-Inspiration (침입자 탐지용 인공 유동감지모의 응답 모델링)

  • Park, Byung-Kyu;Lee, Joon-Sik
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.34 no.4
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    • pp.355-364
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    • 2010
  • Filiform hairs that respond to movements of the surrounding medium are the mechanoreceptors commonly found in arthropods and vertebrates. In these creatures, the filiform hairs function as a sensory system for raider detection. Parametric analyses of the motion response of filiform hairs are conducted by using a mathematical model of an artificial flow sensor to understand the possible operating ranges of a microfabricated device. It is found that the length and diameter of the sensory hair are the major parameters that determine the mechanical sensitivities and responses in a mean flow with an oscillating component. By changing the hair length, the angular displacement, velocity, and acceleration could be detected in a wide range of frequencies. Although the torques due to drag and virtual mass are very small, they are also very influential factors on the hair motion. The resonance frequency of the hair decreases as the length and diameter of the hair increase.

Establishment of the Detention Model for the Prevention of Unban Innundation (도시침수방지를 위한 저류지 모형 확립)

  • Park, Jae-Hong;Han, Kun-Yeun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2006.05a
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    • pp.1656-1660
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    • 2006
  • 도시 주변의 급격한 택지개발, 도시 인구의 집중, 대규모 계획단지의 개발은 유역의 유출특성에 큰 영향을 주게 되고, 도시화가 진행됨에 따라 불투수 표면이 증가되고 침투율이 감소됨으로써 유출계수의 증가요인이 되고 있다. 이에 따라 유역의 자연 저류지 기능이 저하되고, 우수가 하천으로 유입되는 시간이 단축됨으로써 첨두홍수량 뿐만 아니라 유출총량의 증대를 초래하여 도시 주변의 중소하천 유역에서는 막대한 재산 및 인명 피해가 발생하고 있다. 이러한 도시화로 인해 증가된 유출량을 저감시키는 구조적 방안으로 대부분 강우 유출수를 일시 저류하여 유출량을 조절하는 우수유출 억제시설이 권장되고 있으나, 이들 시설에 대한 수리학적 침수방어능력이 명확히 규명되지 못한 실정이다. 본 연구의 목적은 도시지역 침수방지 대책 수립에 필요한 On/Off-Line 저류지의 평가 및 설계에 기존 부정류 모형들의 모의가능성을 평가 비교하고, 가상하도와 실제하도에 적용하여 모형을 검보정 함으로서 저류지 해석의 실용화 모형을 확립함에 있다. 본 연구 결과는 도시지역에 적용할 수 있는 도시홍수방어시스템의 일환으로 구축함으로써, 도시지역에서 저류지 홍수저감효과를 평가하는 등 침수재해와 연계된 구조적 대책 수립에 필요한 기초자료로 활용하고자 한다. 본 연구에서 연구된 저류지 모형을 이용하여 On-Line 및 Off-Line 저류지에 적용한 결과 두 종류의 저류지 모두 홍수방어를 위해 이용될 수 있었다. On/Off-Line 저류지 모두 첨두유량이 발생할 경우 어느정도의 첨두값의 감쇠를 발생시킬 수 있는 것으로 판단된다. 그러나 저류지 상류단의 수위감소는 저류지로 유출로 인해 저류지 상류 하도부에서 유속의 증가를 발생시켰고 이로 인해 수위는 저류지가 존재하지 않는 경우보다 낮게 나타나고 있다. On-Line 저류지의 경우 Off-Line 의 경우에 비해 수위, 유량이 저류지의 상류단에서 크게 나타났다. On-Line 저류지의 경우 Off-Line 의 경우에 비해 같은 값의 첨두홍수량을 저류하기 위해서 상대적으로 넓은 저류면적이 필요한 것으로 나타난다. 대등한 수위감소값의 홍수저감효과를 발휘하기 위해서 본 연구에서는 On-Line 저류지 면적은 Off-Line 저류지에 비 두배 이상이 필요한 것으로 보여졌다.

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A Study on the Fast Removement of Overlaps in Image Morphing Using Mass-Spring System (질량-스프링 시스템을 이용한 이미지 모핑의 빠른 겹침 제거 연구)

  • Choi, Do-Won;Hwang, Chi-Jung
    • Journal of Korea Multimedia Society
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    • v.14 no.10
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    • pp.1262-1274
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    • 2011
  • A fast and stable deformation model is essential for realistic simulation of image morphing. In order to stabilize deformation, we used two internal thin plate mass-spring systems that compute the displacements of the x- and y-components of all nodes on the mesh. The deformation results are globally smoother and more stable due to the direction limitation of thin plate mass-spring systems. One-to-one deformation is one of the important issues in image morphing. We focus on fast removing overlaps in the process of deformation. To rapidly remove overlaps, the external forces are set automatically on four or eight neighboring nodes. The speed of removing overlaps is faster when external forces are set on four or eight neighbouring nodes than when on two neighbouring nodes.

Case Study on the Regionality and Characteristics in the Expression of Modern Chinese Architecture (중국 현대 건축의 지역성 구축 및 표현 특성 사례 연구)

  • Ma, Dong-Qing;Yoon, Ji-Young;Zhang, Jing-Yu
    • The Journal of the Korea Contents Association
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    • v.18 no.3
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    • pp.636-647
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    • 2018
  • This study is to explore the characteristics of contemporary Chinese architecture from the aspects of the regionalism of environment, culture and technology. Six cases of contemporary Chinese architecture which won the world-wide famous were selected and analyzed. The results are the followings; First, the regionalism of environment emphasizes the building's response to the regional environment (topography, climate and regional landscape). Second, the regionalism of culture reflects as the relevance between architecture and community structure, economic patterns, folk customs and other social factors of the region. Third, the regionalism of technology requires the coordination of construction process, structure form, materials and other contents of architecture with the regional environment and culture, and emphasizes the suitability of technology. Environment, culture and technology determine that the regionalism of contemporary Chinese architecture is not purely the meaning at the formal level, but explores the underlying causes.