• Clinical and Experimental Pediatrics
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• v.48 no.8
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• pp.894-900
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• 2005

Purpose : Because of the unavailability of marrow transplantation, umbilical cord blood (CB) is increasingly being used. We evaluated the potential of ex vivo expansion and clonality in CD34+ cells separated from cord blood source and mobilized peripheral blood (PB) in a serum-free media. Methods : The CD34+ cells, selected from CB and mobilized PB, were expanded with hematopoietic growth factors. They were then cultured for burst-forming units of erythrocytes (BFU-E), colony-forming units of granulocytes and monocytes (CFU-GM) and colony-forming units of megakaryocytes (CFU-Mk) at culture days 0, day 4, day 7, and day 14 with various growth factors. Results : The CB-selected CD34+ cells showed significantly higher total cell expansion than those from the PB at day 7 (2 fold increase than PB). The CB-selected CD34+ cells produced more BFU-E colonies than did the PB on culture at days 7 and at day 14. Also, the CB-selected CD34+ cells produced more CFU-Mk colonies than did the PB on culture at day 4 and at day 7. Conclusion : The ex vivo expansion of the CB cells may be promising in producing total cellular expansion, CFU-Mk and BFU-E compared with PB for 7 to 14 days. The growth factors combination including megakaryocyte growth and development, flt3-ligand and interleukin-3 showed more expansion in the view of total cells and clonal maintenance compared with less combination.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.9
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• pp.1079-1086
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• 2012

In this paper, X-band 60 W Solid-State Power Amplifier with sequential control circuit and pulse width variation circuit for improve bias of SSPA module was designed. The sequential control circuit operate in regular sequence drain bias switching of GaAs FET. The distortion and efficiency of output signals due to SSPA nonlinear degradation is increased by making operate in regular sequence the drain bias wider than that of RF input signals pulse width if only input signal using pulsed width variation. The GaAs FETs are used for the 60 W SSPA module which is consists of 3-stage modules, pre-amplifier stage, driver-amplifier stage and main-power amplifier stage. The main power amplifier stage is implemented with the power combiner, as a balanced amplifier structure, to obtain the power greater than 60 W. The designed SSPA modules has 50 dB gain, pulse period 1 msec, pulse width 100 us, 10 % duty cycle and 60 watts output power in the frequency range of 9.2~9.6 GHz and it can be applied to solid-state pulse compression radar using pulse SSPA.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.33 no.3
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• pp.159-169
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• 2020

Acceleration amplification factors, which are variables used in the seismic design of power facilities installed inside substation structures, are presented in the seismic design standards of the United States (US), Japan, and Korea. Unlike the coefficients presented in the design standards of the US and Japan, those presented in domestic design standards can be obtained only by performing dynamic analysis when the substation structure has more than four floors. Because most substation structures in Korea have 4-5 stories, the existing acceleration amplification factor is insufficient to be applied to actual substation structures. To suggest an acceleration amplification factor suitable for domestic substation structure types, the acceleration amplification factor was evaluated for seven representative substation structures. The acceleration amplification factors were evaluated by constructing in-structure response spectra based on a study of far-field and near-fault earthquakes. In general, the acceleration amplification coefficients α_J and α_A according to the US and Japan seismic design criteria tend to be overestimated compared with the acceleration amplification factors obtained through dynamic analysis based on the study of near-fault and far-field earthquakes.

• Geophysics and Geophysical Exploration
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• v.14 no.1
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• pp.69-79
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• 2011

In this study, empirical site amplifications and S-wave velocity profiles for shallow and deep soils are estimated using earthquake ground motion records in metropolitan Manila, the Philippines. We first apply a spectral inversion technique to the earthquake records to estimate effects of source, path, and local site amplification. The earthquake data used were obtained during 36 moderate earthquakes at 10 strong-motion stations of an earthquake observation network in Manila. The estimated Q value of the propagation path is modelled as $54.6f^{1.1}$. Most of the source spectra can be approximated with the omega-square model. The site amplifications show characteristic features according to surface geological conditions. The amplifications at the sites in the coastal lowland and Marikina Valley shows predominant peaks at frequencies from 1 to 5 Hz, while those in the central plateau are characterised by no dominant peaks. These site amplifications are inverted to subsurface S-wave velocity. We, next, discuss the relationship between the amplifications and average S-wave velocity in the top 30m of the S-wave velocity profiles. The amplifications at low frequencies are well correlated with the averaged S-wave velocity. However, high-frequency amplifications cannot be sufficiently explained by the averaged S-wave velocity in the top 30 m. They are correlated more with the average of S-wave velocity over depths less than 30 m.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.18 no.6
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• pp.854-862
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• 1993

All of the CMOS analog and analog-digital systems have composed with several basic circuits, and among them, a important block, the amplifier part can affect the system's performance, Therefore, according to the uses in the system, the amplifier circuit have designed as various architectures (high-gain, low-noise, high-speed circuit, etc...). In this paper, we have proposed a new CMOS differential amplifier circuit. This circuit is differential to single ended input stage comprised of CMOS complementary gain circuits having internally biasing configurations. These architectures can be achieved the high gain and reduced the transistors for biasing. As a results of SPICE simulation with the standard $1.5{\mu}m$ processing parameter, the gain of the proposed circuit have a doubly value of the typical circuit's while maintaining other characteristics(phase margin, offset, etc...). And the proposed circuit is applicated in a simple CMOS comparator which has the settling time in 7nsec(CL=1pF) and the igh output swing $({\pm}4.5V)$.

• Tunnel and Underground Space
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• v.16 no.6 s.65
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• pp.486-494
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• 2006

The horizontal to vertical (H/V) ratio technique in spectral domain is a common useful technique to estimate empirical site transfer function. The technique, originally proposed by Nakamura, is proposed to analyse the surface waves in the micrortremor records. The purpose of this paper is to estimate spectral ratio using observed data at the seismic stations distributed within Southern Korean Peninsula from the Fukuoka earthquake including 11 aftershocks. The results show that most of the stations have fairly good amplification characteristics in low frequency band. However, some of the seismic stations show one (resonant frequency specific to the site) or several local peaks of amplification factors with narrow high frequency band. Even though the site amplification characteristics are important information, we should be careful to analyse the observed ground motions from the seismic stations which have several very high amplification peaks for the deconvolution of seismic source and attenuation parameters.

• Journal of the Korean GEO-environmental Society
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• v.10 no.7
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• pp.135-141
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• 2009

For more reliable estimation of soil-structure interaction and seismic source and attenuation properties, site amplification function should be considered. This study use the Nakamura's method (1989) for estimating site amplification though various methods for the same purpose have been proposed. This method was originally applied to the surface waves of background noise and therefore there are some limitation for applications to general wave energy. However, recently this method has been extended and applied to the S wave energy successfully. This study applied the method to the coda wave energy which is equivalent to the backscattered S wave energy. We used more than 60 observed ground motions from 5 earthquakes which occurred recently, with magnitude range from 3.6 to 5.1 Each station showed characteristic site amplification property in low-, high- and resonance frequency ranges. In the case of comparing these results to those from S wave energy, lots of information to the site classification work can be gained. Moreover, removal of site amplification can give us more reliable seismic source parameters.

• Journal of the Korean GEO-environmental Society
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• v.10 no.1
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• pp.35-41
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• 2009

It is necessary to consider the site amplification for estimating SSI (soil structure interaction) and seismic source with more confidence. The horizontal to vertical (H/V) ratio technique in spectral domain is one of several techniques to estimate empirical site transfer function. The technique, originally proposed by Nakamura (1989), is applied to analyze the surface waves in the microtremor records. However, the application of this technique has been widened to the shear wave energy of strong motions for estimating site amplification. The purpose of this paper is to estimate spectral ratio using observed data at the seismic stations distributed within Southern Korean Peninsula from the Fukuoka earthquake including 11 aftershocks. The results show that each station has the its own characteristics of the specific resonance, high-band, and low-band frequency. The characteristics of the resonance frequency is more important because the quality of the seismic records are dependent on the resonance frequency. The result can be used for the study of site classification and removal of the site amplification effects from observed records can give us more reliable seismic source parameters.

• The Journal of Engineering Geology
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• v.33 no.2
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• pp.293-305
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• 2023

Three ground models are analyzed using a 1g shaking table and laminar shear box (LSB) to investigate the impact of the ground structure on seismic wave amplification during earthquakes. Multi-layer horizontal, embankment, and basin ground models are selected for this investigation, with each model being divided into dense and loose ground layers, Accelerometers are installed during the construction of each ground model to capture any seismic wave amplification owing th the propagation of an artificial seismic wave, sine wave sweep, and 10-Hz sine wave through a given ground model. The amplification of the tested seismic waves is analyzed using the observed peak ground acceleration and spectrum acceleration. The observed acceleration amplification in the multi-layer horizontal ground model is significantly higher the seismic waves that propagated across the dense ground-loose ground boundary compared with those that only propagated through the dense ground. Furthermore, the observed acceleration amplification gradually increases in the central part of the multi-layer embankment and basin models for the seismic waves that propagated across the dense ground-loose ground boundary.

• Proceedings of the KIPE Conference
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• 2013.11a
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• pp.29-30
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• 2013

본 논문에서는 수중통신용 Parametric Array Transducer를 구동하기 위한 고효율 전력증폭기를 제안한다. 수중전력증폭기는 증폭부와 전원부로 나뉘며 증폭부는 Class B push-pull type의 전력증폭기를 사용하며 전력증폭기 구동을 위한 전원부는 기존의 일정전압이 아닌 가변전압을 얻는 Phase-shifted PWM AC/DC 컨버터를 사용하여 고효율로 동작한다. 증폭부는 Class B push-pull type 증폭기를 사용함으로써 뛰어난 선형성이 보장되며 전원 또한 ET(Envelope Tracking)기술을 적용한 가변전압 AC/DC컨버터를 사용하여 고효율로 동작한다. 본 논문에서는 고 효율 수중전력증폭기와 가변전압 AC/DC컨버터의 전력회로를 제시하고 시뮬레이션과 실험을 통하여 특성을 확인하였으며, 수중음향센서를 위한 전력증폭기로 유용하게 사용 될 것을 예상한다.