• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.1 no.1
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• pp.9-14
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• 1995

Thermography is a diagnostic procedures that measures infrared energy emitted by the skin. Thermography detects body temperature change which are controlled by the autonomic nervous system. It does show the thermal dysfunction that correlates closely with pain syndromes as well as normalization when the healing process takes place. Experienced clinical interpretation of the thermal pattern is necessary to diagnose and establish causation. Thermography is useful in the diagnosis of painful conditions such as herniated disc diseases, myofascial syndrome, myositis, musculoligamentous injury, reflex sympathetic dystrophy, athretic injuries, vascular diseases, arthritis, inflammation and breast tumors.

• Journal of Life Science
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• v.30 no.3
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• pp.221-229
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• 2020

Distylium racemosum is an evergreen tree growing wild on Jeju Island, which has been reported to exert biological activity. Obesity is induced by genetic, metabolic, environmental, and other factors. Among these, certain bacterial and viral infections have been shown to cause obesity, which is known as infectobesity. Human adenovirus (HAdV)-36 is one of the viruses that are known to cause infectobesity in humans. Unlike extensive research on preventing obesity and developing anti-obesity drugs, little research has been conducted specifically on the prevention and treatment of infectobesity. Therefore, this study aimed to evaluate the effects of phytochemicals from D. racemosum on the replication of HAdV-36. A549 cells infected with HAdV-36 were treated with an ethyl acetate fraction of a D. racemosum leaf extract (DRE), and the virus titer was calculated based on the hemagglutination (HA) titer. The results showed a concentration-dependent inhibitory effect of DRE treatment on HA titers. DRE treatment was also found to inhibit the cytopathic effects of the virus and the expression of viral genes. Quercitrin was identified as the constituent of DRE exerting an inhibitory effect on HAdV-36 replication. This study shows that DRE can be used as a candidate substance for the development of treatment for HAdV-36 infections. In addition, this study provides a basis to further investigate DRE for the development of anti-infectobesity medication.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.8
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• pp.1107-1113
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• 2018

Ultrasonography and photodynamic therapy have been proposed as useful tools as a treatment for inducing necrosis of cells using reactive oxygen species. Apoptosis is an internal mechanism necessary for cells regardless of damage. Ultrasound has the effect of inducing the apoptosis of these cells, and the frequency of 1 MHz is the most applicable area for medical use. The laser which is generally used in photodynamic therapy has a heat reaction and the treatment is limited. However, as a small light emitting diode is developed, it shows possibility to minimize the equipment and reduce heat reaction. On the other hand, there are relatively few researches on direct effects of light compared with studies using photosensitizers, and the area is also limited. Therefore, in this paper, we have developed a cancer cell proliferation control module using ultrasonic and light emitting diodes, which have relatively few side effects, and quantitatively analyze the effect of the module to propose an optimal suppression technique.

• Journal of Acupuncture Research
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• v.23 no.3
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• pp.91-102
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• 2006

목적 : 이 연구에서는 FBS에 의하여 유도되는 혈관 평활근 세포 증식에 대한 봉약침액과 Melittin의 세포 고사효과의 영향 및 작용 기전을 살펴보고자 하였다. 방법 : $I{\kappa}Ba$, p-$I{\kappa}Ba$, p-ERK1/2, p-Akt, p53, Bcl-2, Bax 및 active caspase-3는 Western blotting을, $NF-{\kappa}B$는 EMSA와 immunofluorescence staining을 이용하여 측정하였다. 결과 : 1. Melittin은 $NF-{\kappa}B$ 활성에 대하여 $I{\kappa}Ba$의 인산화를 유의하게 익제하고 $I{\kappa}Ba$를 증가시켰으며, $NF-{\kappa}B$의 DNA 결합과 $NF-{\kappa}B$ p50의 핵 내 유입을 유의하게 감소시켰다. 2. Melittin은 $NF-{\kappa}B$ 활성을 증가시키는 물질인 Akt의 인산화를 유의하게 억제하였고, ERK1/2의 인산화도 억제하였다. 3. Melittin은 세포사멸 전구 단백질인 p53, Bax 및 caspase-3의 발현을 유의하게 증가시켰고, 세포사멸억제 단백질인 Bcl-2의 발현은 감소시켰다. 결론 : 이상의 결과는 $NF-{\kappa}B$ 와 Akt 활성을 억제함으로써 혈관평활근세포 증식을 억제하는 효과가 있음을 입증한 것이며, 향후 안전성 연구를 바탕으로 혈관성형술 후 재발성협착증과 동맥경화증의 치료제로 사용될 수 있을 것으로 기대된다.

• Korean Journal of Medicinal Crop Science
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• v.11 no.5
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• pp.397-401
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• 2003

Digitalis purpurea L. is a medicinal herb and have been used to congestive heart failure, mycocardial infarction, edema, angina etc. A protocol has been developed for in vitro propagation of adventitious shoot buds directly from leaf segments of D. purpurea Leaf explants of D. purpurea directly formed shoot buds when cultured on a MS medium supplemented with $2\;mg/l$ BA and $0.1\;mg/l$ IAA for 5 weeks. Adventitious shoots were multiplied by subculturing on the $B_5$ medium and shoot elongation was developed by subculturing on the WPM medium. Root formation from the shoot regenerated was achieved on MS basal medium containing 1 mg/ IBA.

• Clinical and Experimental Pediatrics
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• v.46 no.10
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• pp.1029-1031
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• 2003

Hemophagocytic lymphohistiocytosis is a reactive disorder characterized by a generalized non-malignant histiocytic proliferation with prominent hemophagocytosis by stimulated histiocytes in the bone marrow and reticuloendothelial systems resulting in pancytopenia and liver dysfunction. Several diseases including infection, malignancy and autoimmune disease are known to be causative disorders. This case demonstrated histiocytic hemophagocytosis in the bone marrow, resulting in pancytopenia during treatment of systemic lupus erythematosus and did not show any underlying disease.

• Journal of Veterinary Clinics
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• v.17 no.1
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• pp.1-5
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• 2000

Microsporum gypseum을 인공감염시킨 기니픽에서 terbinafine의 치료효과 실험을 위한 전단계 실험으로서 인공감염시킨 기니픽에서 M. gyspeum의 생물학적 주기를 조사하였는데, 이것은 인공감염된 후 효과적인 치료와 평가의 시기를 결정하기 위해 필요하였다. M. gypseum으로 인공감염된 기니픽의 생물학적 주기는 급성기 이후에 자연치유되는 것이 특징이었다. 증식기는 감염 후 5일부터 11일까지 지속되었다. 따라서 다음 번의 치료효과 실험에서 인공감염 당일부터 9일간 계속 terbinafine을 경구투구하고, 마지막 투여 다음 날 진균학적 및 임상적 평가를 하기로 결정하였다.

• Journal of Chest Surgery
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• v.34 no.11
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• pp.883-886
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• 2001

Mediastinal fibrosis is uncommon but may result in entrapment and erosion of vital mediastinal structures by fibrous tissues. Idiopathic mediastinal fibrosis involved esophagus is very rare, and only a few cases have ever been reported. Such idiopathic mediastinal fibrosis involved esophagus is an enigmatic inflammatory fibrous tissue proliferation, but the treatment has not yet been clearly defined. We had successfully treated in such a case with partial esophagolysis and esophagomyotomy.

• 한국생물공학회:학술대회논문집
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• 2001.11a
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• pp.475-478
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• 2001

Ex vivo hematopoietic cells can treat patients suffering from hematopoietic malignancies using bone marrow transplantation therapies. A initial cell density of $1.5{\times}10^6cells/ml$ and a growth factors of IL-3(5ng/ml), SCF(5ng/ml) and FL(25ng/ml) result in a 3.6-fold expansion of LTC- IC but a unexpansion of total cells.

• Journal of the korean veterinary medical association
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• v.24 no.1
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• pp.19-24
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• 1988

A lactating Holstein cow which did not have had responded to drug therapy during 2 months was clinically examined. Right atrial vegetative endocarditis was determined dy ultrasonographic diagnosis, and later it was confirmed at necropsy. An early systolic