• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.4
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• pp.853-860
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• 2007

In this modern era, human beings lead their life in complex environment where there are lots of parameters such as temperature, light, smell, sound, visual stimulus etc. that play important role for quality life. These parameters affect physical and mental behavior of a human being immensely. To ensure quality life the demand for quality products is always associated with human emotion and sensibility. Due to human sensibility and emotion involvement with quality life, the design stages of any kind of product must include some certain features related with emotion and sensibility. The cues for optimizing artificial environment are the physiological responses of human in that environment. The conventional approach of environmental physiology is to measure the relationship between environmental physical parameters and human psychological parameters under artificial conditions. Using that approach we tried to design an artificial environment for our daily lives and activities associated with both physiological and psychological behavior. We developed the technique to present the mock environment and software to measure and evaluate sensibility physiologically or psychologically and a simulator to measure and evaluate sensibility that can be utilized for large scale industrial production and design of environment. Simulator to measure and analyze human sensibility (SMAS) was constructed, which was utilized to estimate human sensibility and to simulate living and office environment.

• The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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• v.5 no.4
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• pp.83-93
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• 1994

1886년 고트리브 다이믈러와 칼 벤즈가 가솔린 자동차를 개발한 이후 100여년이 지난 지금 자동차는 비약적으로 진보, 발전하여 현대 산업사회와 개인의 생활에 있어 산업운송수단과 이동수단으 로서 필요불가결하게 되어 밀접한 관계를 갖고 있다. 우리나라 자동차 공업의 역사는 자동차가 사회적, 경제적 효용에 따라 그 생산과 보유대수가 날이 갈수록 증가 일로에 있으며, 자동차의 생산대수는 전세 계에서 년간 약 50,606천대('94년)로서 중요한 국가 기간 산업으로 자리하고 있다. 한편 전기, 전자공업의 발전에 따른 자동차의 Car Electronics가 많이 채용되게 됨에 따라 현재의 자 동차에는 대부분이 전자제어 System으로 구성되어 있다. 최근에는 Micro Processor를 이용한 전자부품이 많이 사용되어 전자파에 대한 문제가 다양하게 발생 하고 있다. 예를 들면 미국 캘리포니아주에서 전자점화제어장치와 연료분사 장치를 설치한 구미의 자동 차가 주행중 28MHz, 28W의 아마추어 무선을 탑제한 자동차가 통과할 때 엔진이 고르지 못한 보고가 있 었고, 화학섬유로된 옷을 착용한 전자부품이 다른 부품에 영향을 주는 사례가 맣아지고 있다. 따라서 자동차에는 여러가지의 전장품, 전자기기를 탑재하기 때문에 자동차 자체에서 발생하는 것과 외부로 부터 받는 전자장해 EMI(Electromagnetic Interference), EMS(Electromagnetic Susceptibility) 가 문제로 되어 자동차 및 부품 maker에 의한 EMC(Electromagnetic Compatibility) 평가의 중요성이 고조되고 있다. 차제무전기, 차제무전기, Car-Radio는잡음방해를 많이 받기도 하지만, 잡음원이 되기 도 한다. 또한 Engine 제어, 차속제어, Brake 제어등에 이용되는 전자제품은 방해에 의한 오동작 또는 파괴가 발생하여 주행기능, 안전성에 문제가 야기되지 않도록 해야 한다. 이러한 전자기 환경은 모두 RF(Radio Frequence)와 자동차에서의 전자파 장해 문제의 원이 될 수 있다. 자동차 및 그 부품의 전자기 방해에 관한 규격화는 1987년부터 괄목할 만하게 진행되어 이에 따른 규제 움직임이 IEC(International Electrotechnical Commission: 국제전기기술위원회) 산하의 하부기 구인 CISPR(International Special Committeeon Radio Interference: 국제 무선 장해 특별위원회)가 전자기 방해파에 대한 측정법 통일안을 제안 하였고, ISO(International Standardization Organiza- tion: 국제표준화 기구) 가운데 TC 22/SC3가 자동차의 전장품에 대한 장해를 논의히고 있다. 특히, 자동차의 EMC에 관한 국가 규격은 국제 규격에서 저술한 바와 같이 특별히 규정된 것이 없고 VDE(Verband Deutscher Elektrotechniker: 서독전기기술 협회)와 SAE(Society of Automotive Engi- neers: 자동차 기술자 협회)에서 비교적 활발하고 Jaso(Japanese Automobile Standards Organization: 일본 자동차 표준협회)에서 많이 진행중에 있다. 본 고에서는 자동차의 전자제어에 따른 잡음 발생 요인과 전자파 간섭 관련 자동차 규격과 시험평가 방법에 대해 간단히 소개 하였다.

• Tuberculosis and Respiratory Diseases
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• v.46 no.2
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• pp.215-228
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• 1999

Background: Sarcoidosis is a chronic granulomatous inflammatory disease of unknown etiology often involving the lungs and intrathoracic lymph nodes. The natural course of sarcoidosis is variable from spontaneous remission to significant morbidity or death. But, the mechanisms causing the variable clinical outcomes or any single parameter to predict the prognosis was not known. In sarcoidosis, the number and the activity of CD4 + lymphocytes are significantly increased at the loci of disease and their oligoclonality suggests that the CD4 + lymphocytes hyperreactivity may be caused by persistent antigenic stimulus. Recently, it has been known that CD4+ lymphocytes can be subdivided into 2 distinct population(Th1 and Th2) defined by the spectrum of cytokines produced by these cells. Th1 cells promote cellular immunity associated with delayed type hypersensitivity reactions by generating IL-2 and IFN-$\gamma$. Th2 cells playa role in allergic responses and immediate hypersensitivity reactions by secreting IL-4, IL-5, and IL-10. CD4+ lymphocytes in pulmonary sarcoidosis were reported to be mainly Th1 cells. IL-12 has been known to play an important role in differentiation of undifferentiated naive T cells to Th1 cells. And, Moller et al. observed increased IL-12 in bronchoalveolar lavage fluid(BALF) in patients with sarcoidosis. So it is possible that the elevated level of IL-12 is necessary for the continuous progression of the disease in active sarcoidosis. This study was performed to test the assumption that IL-12 can be a marker of active pulmonary sarcoidosis. Methods: We measured the concentration of IL-12 in BALF and in conditioned medium of alveolar macrophage(AM) using ELISA(enzyme-linked immunosorbent assay) method in 26 patients with pulmonary sarcoidosis(10 males, 16 females, mean age: $39.8{\pm}2.1$ years) and 11 normal control. Clinically, 14 patients had active sarcoidosis and 12 patients had inactive. Results: Total cells counts, percentage and number of lymhocytes, number of AM and CD4/CD8 lymphocyte ratio in BALF were significantly higher in patients with sarcoidosis than in control group. But none of these parameters could differentiate active sarcoidosis from inactive disease. The concentration of IL-12 in BALF was significantly increased in sarcoidosis patients ($49.3{\pm}9.2$ pg/ml) than in normal control ($2.5{\pm}0.4$ pg/ml) (p<0.001). Moreover it was significantly higher in patients with active sarcoidosis ($70.3{\pm}14.8$ pg/ml) than in inactive disease ($24.8{\pm}3.l$ pg/ml) (p=0.001). Also, the concentration of IL-12 in BALF showed significant correlation with the percentage of AM(p<0.001), percentage(p<0.001) and number of lymphocyte(p<0.001) in BALF, suggesting the close relationship between the level of IL-12 in BALF and the inflammatory cell infiltration in the lungs. Furthermore, we found a significant correlation between the level of IL-12 and the concentration of soluble ICAM-1 : in serum(p<0.001) and BALF (p=0.001), and also between IL-12 level and ICAM-1 expression of AM(p<0.001). The AM from patients with pulmonary sarcoidosis secreted significantly larger amount of IL-12 ($206.2{\pm}61.9$ pg/ml) than those of control ($68.3{\pm}43.7$ pg/ml) (p<0.008), but, there was no difference between inactive and active disease group. Conclusion : Our data suggest that the BALF IL-12 level can be used as a marker of the activity of pulmonary sarcoidosis.

• Korean Journal of Remote Sensing
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• v.36 no.2_2
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• pp.249-261
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• 2020

Coastal monitoring using multiple platforms/sensors is a very important tools for accurately understanding the changes in offshore marine environment and disaster with high temporal and spatial resolutions. However, integrated observation studies using multiple platforms and sensors are insufficient, and none of them have been evaluated for efficiency and limitation of convergence. In this study, we aimed to suggest an integrated observation method with multi-remote sensing platform and sensors, and to diagnose the utility and limitation. Integrated in situ surveys were conducted using Rhodamine WT fluorescent dye to simulate various marine disasters. In September 2019, the distribution and movement of RWT dye patches were detected using satellite (Kompsat-2/3/3A, Landsat-8 OLI, Sentinel-3 OLCI and GOCI), unmanned aircraft (Mavic 2 pro and Inspire 2), and manned aircraft platforms after injecting fluorescent dye into the waters of the South Sea-Yeosu Sea. The initial patch size of the RWT dye was 2,600 ㎡ and spread to 62,000 ㎡ about 138 minutes later. The RWT patches gradually moved southwestward from the point where they were first released,similar to the pattern of tidal current flowing southwest as the tides gradually decreased. Unmanned Aerial Vehicles (UAVs) image showed highest resolution in terms of spatial and time resolution, but the coverage area was the narrowest. In the case of satellite images, the coverage area was wide, but there were some limitations compared to other platforms in terms of operability due to the long cycle of revisiting. For Sentinel-3 OLCI and GOCI, the spectral resolution and signal-to-noise ratio (SNR) were the highest, but small fluorescent dye detection was limited in terms of spatial resolution. In the case of hyperspectral sensor mounted on manned aircraft, the spectral resolution was the highest, but this was also somewhat limited in terms of operability. From this simulation approach, multi-platform integrated observation was able to confirm that time,space and spectral resolution could be significantly improved. In the future, if this study results are linked to coastal numerical models, it will be possible to predict the transport and diffusion of contaminants, and it is expected that it can contribute to improving model accuracy by using them as input and verification data of the numerical models.