• Microbiology and Biotechnology Letters
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• v.47 no.3
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• pp.323-331
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• 2019

White jelly fungus (Tremella fuciformis Berk; TF) has been used as a traditional medicine in Asia; it is known to prevent hypertension, aging, cancer, and arteriosclerosis. This study aimed to investigate the anti-diabetic effects of fermented Tremella fuciformis Berk (FTF) ethanol extracts fermented with L. rhamnosus BHN-LAB 76. We show that FTF increases the ${\alpha}$-glucosidase inhibitory activity and suppress the adipogenesis of 3T3-L1 adipocytes. These inhibitory effects of FTF are accompanied by the regulation of the phosphorylation of AMPK, JNK, and Akt. These data demonstrate that FTF not only inhibits adipogenesis by affecting the adipogenic signaling, but also increases the anti-diabetic effects by regulating the insulin signaling pathway. Therefore, we suggest that the FTF can be used for developing functional food and cosmetics materials.

• Food Engineering Progress
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• v.21 no.3
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• pp.249-255
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• 2017

Caesalpinia sappan L. is an oriental medicinal plant distributed in the Asia Pacific region including India, Malaysia, and China. The dried heartwood of Caesalpinia sappan has been traditionally used as an analgesic and anti-inflammatory drug. In this study, the effects of extract methods of C. sappan on contents of total polyphenols and flavonoids, antioxidant activity, and cytotoxic activity were evaluated. As a result, hot water extract from C. sappan (CSWE) significantly exhibited contents of total polyphenols and flavonoids (22.6 mg GAE/g and 14.5 mg QE/g) higher than 70% ethanol extract (CSEE) (17.6 mg GAE/g and 13.2 mg QE/g). However, CSEE showed greater antioxidant activity than CSWE in both DPPH and ABTS. Also, the cytotoxicity of C. sappan against three kinds of cancer cell lines was higher in CSEE than in CSWE. These results show that ethanol extract is a better extract method than hot water method to maintain antioxidant and anti-cancer activities.

• Journal of Life Science
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• v.31 no.2
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• pp.149-157
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• 2021

Prunus mume Sieb. et Zucc is widely distributed in East Asia (Korea, Japan, and China), and its fruit is often used as a medication and food material. However, because most previous studies have only investigated the state of Prunus mume fruit extract, studies on the various ways of processing this extract are still needed to increase its utilization. In this study, we evaluated the physicochemical properties and physiological activities of spray-dried Prunus mume vinegar powder (SPP). The sugar content, pH, total acidity, and moisture content of the SPP were 8.90 °Brix, 3.19, 1.05%, and 3.07%, respectively. The SPP exhibited significantly high antioxidant activity in terms of DPPH radical scavenging activity (65.55%), reducing power (1.48), and hydrogen peroxide scavenging activity (48.07%). In addition, the SPP remarkably decreased the cell viability of human breast MDA-MB-231 and human skin cancer SK-MEL-28 in a dose-dependent manner. The morphological results of the treatment of MDA-MB-231 cells with SPP were distorted, shrunken cell masses. Furthermore, apoptotic bodies and nuclear condensation formed in the SPP-treated MDA-MB-231 cells. The total polyphenol and flavonoid contents of the SPP were 59.58 ㎍/g (gallic acid equivalent) and 57.56 ㎍/g (quercetin equivalent). The results of this study indicate that SPP, which has antioxidant activity and anticancer effects, can be useful in the development of natural medicines and functional food ingredients.

• (The)Study of the Eastern Classic
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• no.35
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• pp.359-385
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• 2009

The study aims to investige how Soupjin, military training has been changed in early Joseon Dynasty. The conclusions are following these. First, Jin means military marching or attacking the enemy and Jinbeop means how to make Jin or traning but now Jinbeop indicates textbook of Jinbeop rather than practing it. Second, publishing Owijinbeop is completed as a result of continuous series of Jinbeop textbook and Owi systems are built up by military construction reorganization. Third, the total number of articles is 268 from Taejo to Seonjo in early Joseon Dynasty. They are divided into different parts according to kings. Forth, Taejo, Taejong, Munjong, Sejo, Yejong and Jungjong are the kings who take the lead of Jinbeop training directly. Among them Munjong and Sejo are highly considered that they edited and revised Sinjinbeop and tried to unify military organization. Besides Jungjong discussed Jinbeop textbooks which are published by prior kings and even make them be practiced. But after Imjinwaeran, Seonjo accepted the book Gihyosinseo by Cheokgyegwang in China and transformed our Jinbeop for protecting the country. Firth, We found that Hyangmyung and Jintoigyjak had been focused from Sejo to Jungjong. Because in this period Joseon had to find the way to protect the country from north Yeojin, But after Imjinwaeran Seonjo introduced Cheokgyegwang's Jeolgangjinbeop in China because of Japanese attacks.

• Journal of Wetlands Research
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• v.23 no.1
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• pp.94-105
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• 2021

Two vertical flow biofilters in series (BFS) employing synthetic fiber (FBF) followed by woodchip (WBF) was investigated in order to assess its potential as an alternative to the typical vertical-horizontal flow configuration in removing nonpoint source pollutants specifically nutrients and organics. These lab-scale column biofilters were operated for 176 days alongside three other columns that were added for control and sampling purposes. The biofilter columns were fed with either a semi-artificial piggery stormwater or artificial stormwater with specific ammonia and nitrate contents. Results reveal that the BFS was more effective than a single biofilter in removing pollutants especially nitrogen. FBF was found to remove up to 100% of ammonia from the stormwater with corresponding increase in nitrate in the outflow which shows evidence of active nitrification. Meanwhile, the succeeding vertical WBF was able to subsequently remove 77% of the nitrate. The effective reduction of nitrate in a vertical flow biofilter was believed to be due to the use of woodchip which can provide a carbon source that is required for denitrification. However, further investigation is needed to support this claim. Nonetheless, the study shows the potential of vertical flow BFS as a nitrogen removal mechanism especially in areas where enough land space for horizontal flow biofilters is limited.

• The Journal of the Korea Contents Association
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• v.21 no.8
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• pp.123-136
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• 2021

The Palace Museum Cultural Creative Products on Attitude and Purchasing Intention. Online surveys were conducted on consumers who had consumed Cultural and Creative Products of the Palace Museum in the past. There were 305 valid questionnaires empirical survey was analyzed. The results of the study are as follows. First, it was found that all three variables of Consumer Perceived Value had a significant positive effect on product Attitude. Second, among the three variables of Consumer Perceived Value, the Cultural Educational Value did not significantly affect the onsumer urchasing ntention, but other variables had a significant positive effect on the Consumer Purchasing Intention. Third, it was verified that Attitude has a positive effect on Purchasing Intention. Fourth, it was found that there was a partial mediating effect of the Attitude between the Perceived Value and the Consumer Purchasing Intention. According to the research results, while maintaining the cultural identity of cultural and creative products, it is necessary to adopt reasonable methods to maximize the sense of enjoyment and comfort, enriching the daily use functions and rationalizing the price standards.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.22 no.6
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• pp.155-163
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• 2022

In order to avoid the spread of Covid-19, outdoor activities are decreasing worldwide and the time spent at home is increasing. As physical activity declines, the number of people who feel bored, restless and immune deficient is increasing. As indoor life becomes more permanent, multiple approaches to home workout are becoming active. This paper examines how the Covid blue (boredom and social anxiety) produced in the no-touch era affects quality of life through the use of home training applications. Questionnaires were collected from Chinese people using a website dedicated to Chinese questionnaires, and finally 383 appropriate data were analyzed using SPSS24.0 and AMOS24.0. The research results showed that the actual experience of using home workout had a positive impact on quality of life. The higher the user's sense of social unease about being late in the untact, It was found that the higher the social anxiety perceived by users about the untact era, the higher the interactivity and exercise satisfaction with the home workout app. Home workout application can improve exercise satisfaction and quality of life, which are more positive effects beyond the result of resolving consumers' boredom. Therefore, it can be used as a channel for digital services.

• The Korea Journal of Herbology
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• v.33 no.6
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• pp.71-78
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• 2018

Objectives : This study was fulfilled to investigate nominee materials as anti-inflammatory agent from ethanol extract of Chinese medicinal plants in Yanjin. Among the 20 candidates, we selected most effective one, the ethanol extract of Cicuta virosa L. (CVL). The mechanism underlying the anti-inflammatory effects of CVL is not clearly identified as yet. Accordingly, we clarified the anti-inflammatory effects of CVL and its underlying molecular mechanisms in LPS-stimulated RAW 264.7 macrophages. Methods : RAW264.7 macrophages were incubated with CVL (12.5, 25, or $50{\mu}M$) and/or lipopolysaccharide (LPS) ($1{\mu}g/m{\ell}$). Cytotoxicity was determined using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay and the level of nitric oxide (NO) production was measured with Griess reagent. The prostaglandin $E_2$ ($PGE_2$) production was measured with enzyme immunoassay kits and the protein expression of inducible nitric oxide synthase (iNOS) was determined using Western blot analysis. Results : Among the 20 ethanol extract of Chinese medicinal plants of Yanjin tested, CVL significantly reduced the production of NO in a dose-dependent manner via inhibition the protein expressions of iNOS without cytotoxicity on the LPS-stimulated RAW 264.7 macrophages. In addition, CVL also effectively declined the production of $PGE_2$ in LPS-simulated RAW 264.7 macrophages. Conclusions : Taken together, these data presented in this study demonstrate that CVL possesses anti-inflammatory activity by suppressing the production of pro-inflammatory mediators NO and $PGE_2$, and pro-inflammatory protein iNOS expression in LPS-stimulated RAW 264.7 macrophages.

• Asia Marketing Journal
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• v.13 no.4
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• pp.253-264
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• 2012

A growing number of Korean companies are trying to expand their business area into global market due to saturation in the Korean domestic market. Home shopping industry arriving on mature stage is faced with less growth recently. CJ O Shopping which is a top ranked home shopping company in Korea, has been showing meaningful performances by earlier moving to global market with thorough preparations. CJ O Shopping's global marketing strategy focused on asian countries including China, India, Vietnam, and Japan is going successfully, which enables top ranked on-line retailing company in asia as well as in Korea. CJ O Shopping effectively penetrated into overseas market with both core competence based on Korean home shopping model and rigorous preliminary study on target market. Especially shoppertainment (Shopping+Entertainment) that is unique feature of globally competitive Korean home shopping created huge differentiations in target market. Also choosing the influential local partner, sharing the business goals, and building the joint venture could make stable operations, thereby easily earning of well-established awareness from target consumers. A step ahead entry of competitors and intensive localization of CJ O Shopping's core competence for arriving safe in target market were additional key factors for global marketing success. We can extract above key factors for success as implications of case study on CJ O Shopping's global marketing, and expect those factors to be spread into lots of Korean companies and utilized as successful strategies for global marketing.

• Advanced Industrial SCIence
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• v.1 no.1
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• pp.7-15
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• 2022

To adopt the development in the medical scenario IoT developed towards the advancement with the processing of a large amount of medical data defined as an Internet of Medical Things (IoMT). The vast range of collected medical data is stored in the cloud in the structured manner to process the collected healthcare data. However, it is difficult to handle the huge volume of the healthcare data so it is necessary to develop an appropriate scheme for the healthcare structured data. In this paper, a machine learning mode for processing the structured heath care data collected from the IoMT is suggested. To process the vast range of healthcare data, this paper proposed an MTGPLSTM model for the processing of the medical data. The proposed model integrates the linear regression model for the processing of healthcare information. With the developed model outlier model is implemented based on the FinTech model for the evaluation and prediction of the COVID-19 healthcare dataset collected from the IoMT. The proposed MTGPLSTM model comprises of the regression model to predict and evaluate the planning scheme for the prevention of the infection spreading. The developed model performance is evaluated based on the consideration of the different classifiers such as LR, SVR, RFR, LSTM and the proposed MTGPLSTM model and the different size of data as 1GB, 2GB and 3GB is mainly concerned. The comparative analysis expressed that the proposed MTGPLSTM model achieves ~4% reduced MAPE and RMSE value for the worldwide data; in case of china minimal MAPE value of 0.97 is achieved which is ~ 6% minimal than the existing classifier leads.