• Journal of IKEEE
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• v.28 no.1
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• pp.97-103
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• 2024

Some drugs can offer far better medical effectiveness as it is injected through the intradermal layer of the skin, known as a needle-free injection. However, conventional needle-free devices might deliver a relatively large amount of drug in a just single spot of skin, splitting open the tissue layer structure, which might cause bruising and bleeding. By injecting the small volume with a fast repetition rate in a large surface area of skin, the patient may get much fewer injuries and pain. To achieve that specification, the driving force must be instantaneous and short-pulsed. Such a form of an injection device has been developed but the efficacy of those devices has been rarely examined. Therefore, this study developed the laser-induced microjet device that ejects microjet whose speed is ~310 m/s, during the 400~800 ㎲ of pulse time. The device can eject ~1 µL of the drug at the rate at which each shot repeated 10 shots per second. Using this specification, we evaluated the efficacy of drug injection onto mouse models. After injecting the insulin solution into the mouse model, the blood insulin level is detected, resulting in 20 % of blood insulin level with the ordinary needle syringe injection method.

• Journal of the Korean Society of Propulsion Engineers
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• v.19 no.5
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• pp.15-21
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• 2015

The thermal decomposition characteristics of the ZPP(Zirconium/Potassium perchlorate), widely used as a primary charge of initiators, were investigated by differential scanning calorimetry(DSC). The DSC results with different heating rates were elaborated with AKTS-Thermokinetics software for the determination of the kinetic parameters of the thermal decomposition of ZPP. There was good agreement between the experimental and the simulation curves, based on the determined kinetic parameters, which indicates the validity of the kinetic description of the thermal decomposition process of ZPP.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.10a
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• pp.512-513
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• 2017

In this paper, an automatic sowing system which arranges the seeds gathered using inhaling technique, on the upper part of cells in trays, is developed to improve the sowing efficiency. In the system, the seeds in inhaled into the vacuum drum, then the seeds are exhausted and arranged on the rotating tray, resulting in rapid sowing system. Also, the velocity control algorithm for the conveyor belt transporting tray is developed to compensate the velocity error generated while the belt is carrying the tray. The velocity control algorithm controls the pulses applying to the stepper motor rotating the drum.

• Journal of the KSME
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• v.32 no.5
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• pp.420-428
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• 1992

1980년대부터 새롭게 우리에게 다가온 nm의 세계는 그 동안 마이크로의 기술이 인류에게 가져다 준 성과 이상의 것을 약속하고 있다. Nanoscience와 Nanotechnology라는 용어가 차츰 일상적인 것이 되어가고 있으며 이들 기술을 응용한 제품들이 선을 보이고 있다. STM은, 개발된지 10년이 되는 현 시점에서 다른 분야들에 기술적으로 많은 파급효과를 끼쳤으며 STM자체의 성능도 크게 향상되었다. 앞으로도 성능 향상은 빠른 속도로 진행될 것이며 특히 단순한 측정장치를 넘어 가공과 제조장치로서 크게 기대가 된다. 다양한 형태로 결합된 개별 원자들의 성질을 측정함으 로써 거시적으로 나타나는 여러 복합적인 현상들을 근본적으로 이해할 수 있고 또 nm 수준에 서의 공정제어로 품질 좋은 무결점의 제품 생산을 가능하게 해 줄 것이다.

• Proceedings of the KAIS Fall Conference
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• 2002.11a
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• pp.258-259
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• 2002

본 연구는 304 STS을 전해연마하여 표면의 조도를 나노 단위까지 제어하기 위한 leveller의 개발이 목적이다. 이를 위해서 AFM을 이용하여 조도를 측정하였고 분극실험을 통해 표면특성을 연구하였다. 전해연마는 인산:황산:증류수를 8:1:1 비율로 전해액을 만들었고 부가적으로 첨가제를 넣어 전해연마를 실행했다. 분극실험은 일정한 전극간격을 유지하여 정전압 조건에서 1mV/s의 속도로 주사하여 실험하였다. 전해연마 시간이 증가함에 따라, 첨가제의 양이 적게 들어갈수록 평활도가 향상됨을 볼 수 있었다.

• Journal of the KSME
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• v.32 no.2
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• pp.175-183
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• 1992

모아레토포그라피를 이용한 금형제작을 위한 클레이모형(clay model)의 3차원 형상측정을 위한 방법이 제시되었다. 그리고 모아레무늬를 해석하는 방법이 제시되어 클레이모형의 형상을 측정 하였고 디지털영상처리기법을 사용하는 일련의 과정을 통해 3차원 형상을 재현하였다. IBM PC/386과 CCD 카메라를 사용하여 실험한 결과 0.005mm의 분해능을 가지며 측정속도가 5분 가량이 소요되었다. 따라서 광학적방법이 접촉식 디지타이징을 이용하였을 경우 발생하는 많은 문제점 등을 효율적으로 보완할 수 있다. 그리고 품질검사를 자동화할 수 있는 방법을 제시하 였고 기존의 모아레토포그라피가 가지는 어려움을 극복하기 위하여 새로운 방법인 주사식 모아 레토포그라피를 제시하였다.

• Journal of the Korean Society of Propulsion Engineers
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• v.3 no.1
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• pp.95-103
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• 1999

Low pressure combustion characteristics of the composite solid propellants were studied in terms of the propellant burning rate, ignition processes, and the structure of the extinguished surfaces. Optical Vacuum Strand Burner(OVSB) system was designed and configured for this purpose. Burning rates of the propellants were measured at subatmospheric pressure by developed test method in OVSB. The ignition and combustion phenomena of the studied propellants in the combustion chamber of OVSB were recorded and analyzed with the camera and VCR(30 frames/s). Burning surfaces of the propellants were extinguished by rapid depressurization method and analyzed with Scanning Electron Microscope(SEM).

• Journal of the Korean Society of Propulsion Engineers
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• v.19 no.1
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• pp.33-41
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• 2015

The kinetic analysis of energetic materials using Differential Scanning Calorimetry (DSC) is proposed. Friedman Isoconversional method is applied to DSC experiment data and AKTS software is used for analysis. The proposed kinetic scheme has considerable advantage over the standard method based on One-Dimenaionl Time to Explosion (ODTX). Reaction rate and product mass fraction simulation are conducted to validate extracted kinetic scheme. Also a slow cook-off simulation is implemented on $B/KNO_3$ for validating the applicability of the extracted kinetics scheme to a practical thermal experiment.

• Journal of Nutrition and Health
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• v.21 no.4
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• pp.242-252
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• 1988

In vivo effects of leucine on skeletal muscle protein synthesis in fed and I-day food deprived young rats were examined. Animals assigned to leucine group were given a single i.p. injection of 80 or 160flmoles of leucine while control group animals were saline sham injected. The rate of protein synthesis was measured by the amount of $^{14}\textrm{C} incorporated into muscle protein after a single injection of $^{14}\textrm{C}-tyrosine, IO$\mu$ Ci/l00g B.W. Examined muscles were two different types of hind limb muscles. the oxidative solues and the glycolytic EDL and plantaris. Administered leucine elevated the concentration of free leucine in soleus muscles by 4-6.8 times the normal level. A massive dose of leucine, 160 flmoles, stimulated protein synthesis in the EDL and plantaris by 24 %, 29 % respectively of straved rats. The soleus of I-day food deprived rats and both types of muscles in fed rats did not respond to the injected leucine. The synthesis rate of the EDL and plantaris was supressed to one-half of the normal while the soleus that was not stimulated by leucine maintained a relatively normal rate, 78 %, of protein synthesis after I-day of food deprivation. Thus, in vivo stimulatory effect of leucine appears to be not a general phenomenon but to be related to the degree of catabolic condition developed by stress such as food deprivation. Although anabolic effects of leucine observed in this study was limited, any applicability of this special property of leucine to human subjects for the purpose of protein sparing in skeletal muscles remains to be examined.

• Journal of the Korean Society of Propulsion Engineers
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• v.20 no.2
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• pp.46-55
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• 2016

The kinetic analysis of a heavily aluminized cyclotrimethylene-trinitramine(RDX) is conducted using differential scanning calorimetry(DSC), and the Friedman isoconversional method is applied to the DSC experimental data. The pre-exponential factor and activation energy are extracted as a function of the product mass fraction. The extracted kinetic scheme does not assume multiple chemical steps to describe the complex response of energetic materials; instead, a set of multiple Arrhenius factors is constructed based on the local progress of the exothermic reaction. The resulting reaction kinetic scheme is applied to two thermal decomposition tests for validating the reactive flow response of a heavily aluminized RDX. The results support applicability of the present model to practical thermal explosion systems.