• Proceedings of the Plant Resources Society of Korea Conference
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• 2021.04a
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• pp.12-12
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• 2021

최근 길어진 여름 및 이상고온 현상이 지속됨에 따라 심화되는 광노화 피부의 특징으로는 건조, 굵고 깊은 주름, 탄력저하 및 불균일한 색소침착 등이 나타나게 됨. 화장품 소재는 기존 광노화 관련 화학물질인 Retinol 등을 대체하기 위해 자연 유래 성분을 적용한 신소재 연구를 진행하고 있음. 흰목이버섯(Tremella fuciformis)은 흰목이목에 속하는 버섯류로 자실체는 한천질로서, 주름이 되어 갈라져 있거나 또는 귓불 모양을 이루고 있으며, 크기는 10 cm 정도이다. 중국에서는 보양식의 주재료로 쓰일 만큼 탁월한 항노화 효능이 알려져 있다. 본 연구에서는 흰목이버섯의 자실체에서 추출하여 정제한 β-Glucan의 성분 확인, in vitro 수준의 피부 항노화 효과, 동물대체 독성 시험을 통한 피부독성 확인 및 인체 피부유효성 평가를 통한 항노화 효과를 확인하였다. 흰목이에서 추출, 정제 후 Bio-LC를 통한 유리당 분석 결과 Mannose, Fucose, Glucose를 확인하였으며, Human Keratinocyte에 UVB를 조사하여 광노화를 유발한 피부세포에 피부 자극 및 탄력저하 인자인 IL-6, TNFa 및 MMP-1을 평가한 결과 농도 의존적으로 현저히 개선됨을 확인하였다. 또한 보습 및 피부장벽 개선 인자인 Filaggrin과 Involucrin 생성효능을 평가한 결과 매우 높이 생성됨을 확인하였다. 본 연구결과를 토대로 광독성, 피부감작성 및 안점막 동물대체 독성시험을 실시한 결과 무독성임을 확인하여 피부에 안전하면서 효능이 우수한 것을 in vitro 수준에서 확인하였고, 피부 홍반완화, 주름개선, 탄력개선 및 보습증가 등 광노화 예방효과를 인체를 대상으로 평가한 결과 유의적인 홍반완화, 주름개선, 탄력 및 보습증가효과를 확인하였다. 본 연구결과를 종합하여 볼 때 흰목이버섯에서 추출, 정제한 β-Glucan은 in vitro 수준에서 자외선으로 인한 피부 트러블 완화, 탄력 및 보습개선을 확인하였고 독성시험을 통해 무자극임을 판정하였으며, 인체유효성 평가를 통해 광노화 예방효과를 확인하였으며 본 결과를 통해 아시아 및 글로벌 시장으로 천연유래 항노화 소재로 확장하고자 한다.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.3
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• pp.276-282
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• 2009

Wrinkling in the flange and wall of a deep-drawn part is one of the major defects in sheet metal processes. Wrinkling is influenced by many factors, such as material properties, shape of the body, forming conditions, stress state and thickness, etc. It is difficult to analyze the wrinkling initiation and growth according to the factors because the effects of the factors are very complex and the wrinkling behavior may show wide variation even though small deviation of factors. In this study, the influence of wrinkling parameters, such as material properties (Al1050, Al5052), the blank holding force and the drawing depth on the wrinkling initiation and growth is investigated by using the experimental method and the dynamic explicit finite element analysis. From the results, it is shown that the dynamic explicit finite element method can be used effectively to prevent the wrinkling problems advancely in the deep drawing process. Also, there is a good agreement between the experimental result and the dynamic explicit finite element analysis.

• Journal of the Korean Institute of Gas
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• v.13 no.4
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• pp.22-26
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• 2009

In this paper, the displacement behavior and strain energy density characteristics of a safety helmet with various corrugation dampers has been analyzed based on the finite element analysis. The safety helmet is to protect impact forces and to absorb the impact energy. Three different helmet models with a corrugation damper have been compared as functions of the displacement and strain energy density characteristics when the maximum external impulsive force is imposed on the summit of the helmet. The computed FEM results show that the extruded corrugation damper is very useful to increase the damping effect of the helmet. This study indicates that the round corrugation damper may absorb the transferred impact energy successfully. Thus, this paper recommends round and long corrugation damper on the lower part of the helmet as a new design element.

• The Journal of the Convergence on Culture Technology
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• v.4 no.3
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• pp.197-207
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• 2018

The radish skin and radish greens (mucheong) are an edible part of the radish. But they are removed before eating the radish and used as a byproduct or an animal feed material because of their tough and rough texture. This study was conducted to investigate the effect of supercritical heat-treated radish-extract on UV-induced Hos: HRM-2 wrinkled mouse animal model on anti-aging wrinkles. Supercritical heat-treated radish-extract was applied on the back of seven-weeks old HRM-2 mice. The effect of HRE on skin thickness, elasticity and wrinkle formation of the mice was observed by using UVB lamp to induce melanogenesis and wrinkle formation. As the result, increased depth of wrinkles was observed in the negative control group in comparison to the normal group. In contrast, decreased depth of wrinkles was observed in the radish-extract-free group compared to the negative control group. In the study of the effect of radish-extract on wrinkle-formation related gene expression and protein what protein expression, MMP-2 and MMP-2 gene expression significantly increased in the negative control group compared to the normal group. The gene expression reduced independence to the mass of radish-extract treated. Similar to quantitative results of mRNA expression, the expression of MMP-2 protein increased as a result of UVB-irradiation. The MMP-2 expression was inhibited in dependence to the mass of radish-extract treated. In conclusion, the supercritical heat-treated radish-extract has an effect on improving skin wrinkles not only when it is applied to the skin but also when orally ingested. Thus, it can be effectively used as a composition to health functional products. Thereafter, we can also conclude that radish, a food that does not show any side-effects even upon long-term intake, can reduce wrinkle formation as well as improve skin elasticity when taken regularly for a long period.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.11
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• pp.965-973
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• 2010

Numerical analysis has been carried out to investigate the heat transfer characteristics of a plate heat exchanger. The multi-cell models with inlet part and outlet part are used for performing numerical simulation. The plate heat exchanger is characterized by chevron angle of $15^{\circ}$, corrugation pitch of 24mm and corrugation height 6~12mm. The length of the inlet-part considered in the analysis ranges from 24.8 to 124mm and Reynolds numbers range from 1,000 to 10,000. The correlations such as friction factor and Colburn factor are compared with previous experimental data. The results can be utilized for designing the plate heat exchanger.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.36 no.1
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• pp.1-8
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• 2012

Numerical analysis has been carried out to investigate the fully developed flow and heat transfer characteristics of a plate heat exchanger. Multi-cell models with an inlet part and outlet part are used to perform the numerical simulation. The plate heat exchanger is characterized by a chevron angle of $20^{\circ}$ and a P/H ratio of 2.0~4.0. The working fluid is water and the Reynolds numbers range from 300 to 1,500. The correlation is given in the form of $f=CRe^m$ for the friction factor and $j=CRe^m$ for the Colburn factor. It is found that the fully developed flow starts from the third cell and the Nusselt number increases with decreasing P/H ratios.

• Journal of the Korean Society of Marine Environment & Safety
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• v.19 no.6
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• pp.597-605
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• 2013

This study was conducted in warty sea squirt farm, Jindong Bay(10 stations; July, October, January, April) for the culture period of Styela clava, Styela plicata. We utilized water temperature, chlorophyll a, suspended particulate matter, hydrodynamics, salinity and dissolved oxygen saturation for the suitability assessment of warty sea squirt farm. Newly, Life Requisite Suitability graphs were made for the correlation between the growth of Styela clava, Styela plicata and farm environment. As a result of the assessment for Habitat Suitability Index, western bay(HSI 0.32~0.41) show values higher than eastern bay(HSI 0.19~0.27). This result shows the high correlation with the unit production of Styela clava, Styela plicata($R^2$=0.834, P<0.01). This could be helpful for fishery management for the sustainable productivity through the scientific suitable site assessment.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.30 no.2
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• pp.221-225
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• 2004

The root of Panax ginseng C. A. Meyer has been used as a traditional anti-aging and anti-wrinkle agent in the Orient. However, it is still unknown which component of ginseng is effective at suppressing wrinkle formation. Recently at least twenty ginsenosides regarded as the main active ingredients of ginseng have been isolated. Among them, we examined the effect of ginsenoside Rg3 on dermal ECM metabolism to elucidate the mechanism of anti-wrinkle by ginseng. In our study, to investigate the anti-wrinkle effect of the ginsenoside Rg3, ECM component and growth factor in dennis were evaluated by ELISA assay. Ginsenoside Rg3 was found to stimulate type I procollagen and fibronectin (FN) biosynthesis in a dose-dependent manner in normal human fibroblast culture (p < 0.05, n =3), and dose-dependently enhance TGF- ${\beta}$1 level (p < 0.05, n =3). In RT-PCR analysis mRNA level of c-Jun, a member of AP-1 transcription factor, was reduced by ginsenoside Rg3 in normal human fibroblast culture. These results indicate that ginsenoside Rg3 stimulates type I collagen and FN synthesis through the changes of TGF - ${\beta}$1 and AP-1 expression in fibroblasts.

• Journal of Korean Society of Disaster and Security
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• v.14 no.1
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• pp.1-8
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• 2021

A corrugated pipe is widely used in firefighting equipment and sprinkler pipes because of its elasticity, which is less damaged by deformation and convenient facilities. However, the corrugated shape of the wall results in complex internal turbulent flow, and it is difficult to predict the pressure drop, which is an important design factor for pipe flow. The pressure drop in the corrugated tube is a function of the shape factors of the pipe wall, such as groove height, length, and pitch. Existing studies have only shown a study of pressure drop due to length changes in the case of D-shaped tubes with less than 5 pitch (P) and height (K) of the rectangular grooves in the tube. In this work, we conduct a numerical study of pressure drop for P/Ks with length and height changes of 2.8, 3.5 and 4.67 with Re Numbers of 55,000, 70,000 and 85,000. The pressure drop in the corrugated tube was interpreted to decrease with smaller P/K. We show that the pressure drop is affected by the change in the groove aspect ratio, and the increase in the height of the groove increases the recirculation area, and the larger the Reynolds number, the greater the pressure drop.

• Nuclear Engineering and Technology
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• v.20 no.4
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• pp.241-245
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• 1988

It is very important to investigate the behaviors of the material parameters governing PCI fuel failure during power ramp because PCI fuel failure is considered to be related to the operations limits of power reactors. In this study, the behavior characteristics of the material parameters such as hoop stress, hoop strain, ridge height, creep strain rate and strain energy in cladding were studied as a function of the operating parameters such as power shock and ramp rate. The FEMAXI-IV fuel rod performance analysis code was used for this study.