• Polymer Science and Technology
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• v.15 no.3
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• pp.274-285
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• 2004

콜로이드 결정 (Colloid crystal)이란 용액 상에서 부유 하는 작은 입자들의 자기 조립 (self-assembly)에 의해 형성된 주기적인 2차원 혹은 3차원 구조를 말한다. 이러한 결정 구조는 광학 필터나 스위치, 광 밴드 갭 재료, 바이오 센서 등의 과학 기술적인 응용을 비롯하여 액화 물질의 상 변화 등과 같은 물리적 현상을 규명함에 있어서 중요한 모델을 제시한다. 특히 최근에 콜로이드의 자기 조립체는 자연적으로 갖게 되는 주기적인 유전율 변화 때문에 빛의 진행 방향이나 특성을 조절할 수 있는 광자 결정 (Photonic Crystal) 구조 제작의 경쟁력 있는 접근 방법으로 각광 받고 있다. (중략)

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2015.11a
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• pp.293-293
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• 2015

최근 다층 코팅의 합성을 통해 코팅의 경도, 내마모성 등의 기계적 물성을 향상시키는 연구가 활발히 진행되고 있다. 본 연구에서는 높은 경도, 낮은 마찰계수, 우수한 고온 특성을 함께 나타내기 위해 CrZrN/CrZrSiN 다층 코팅을 설계하였고, 이중층 주기를 조절하여 CrZrN/CrZrSiN 다층 코팅의 물성변화를 확인하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10c
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• pp.142-144
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• 2003

그리드 환경은 수많은 컴퓨팅 자원을 활용하는 시스템으로 자원에 대한 정보가 필요하다. 자원 정보 검색을 위해서는 모니터링이 전체 자원에서 일어나야 하므로 이에 따른 오버헤드가 예상된다. 본 논문에서는 모니터링의 오버헤드를 줄이면서도 효율적으로 정확하게 자원 정보를 수집 할 수 있는 모니터링 기술을 구현하였다. 여기서 제안된 모니터링 기술은 시스템 성능에 따라 자동적으로 모니터링 주기를 조절하게 된다. 이를 통해 모니터링에 의한 오버헤드가 줄었음을 측정 결과를 통해 보일 것이다.

• Journal of Life Science
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• v.28 no.8
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• pp.985-991
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• 2018

Biological clocks are the basis of temporal control of metabolism and behavior. These clocks are characterized by autonomous free-running oscillation and temperature compensation and are found in animals, plants, and microorganisms. To date, various biological clocks have been reported. These include clocks governing hibernation, sleep/wake, heartbeat, and courtship song. These clocks can be differentiated by the period of rhythms, for example, infradian rhythms (> 24-hr period), circadian rhythms (24-hr period), and ultradian rhythms (< 24-hr period). In yeast (Saccharomyces cerevisiae), at least five different autonomous oscillations have been reported; (1) glycolytic oscillations (T = 1~30 min), (2) cell cycle-dependent oscillations (T = 2~16 hr), (3) ultradian metabolic oscillations (T = 15~50 min), (4) yeast colony oscillations (T = a few hours), and (5) circadian oscillations (T = 24 hr). In this review, we discuss studies on oscillators, pacemakers, and synchronizers, in addition to the application of biological clocks, to demonstrate the nature of autonomous oscillations, especially ultradian metabolic oscillations of S. cerevisiae.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2003.09a
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• pp.37-37
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• 2003

목적 : 일반적으로 세기조절방사선치료 조사면의 작은 조각 크기에 대해, 이상적인 플루언스 지도 혹은 치료계획장치로부터의 최적화된 결과에 가까운 선량분포에서 더 좋은 leaf sequence를 얻을 수 있다. 한편, 치료중 장기의 움직임이 가장 작은 조각 크기의 선택을 방해하는 문제는 항상 존재한다. 게다가, 전통적인 정지 조사면과 달리 표적이 움직이는 동안 조사면 자체도 움직이므로 움직이는 표적에 대한 세기조절방사선치료의 경우에서 적절한 표적 마진에 관한 질문이 제기되어왔다. 따라서, 이 연구에서는 조각 크기에 대한 치료중 표적 움직임의 효과를 연구하였다. 대상 및 방법 : 세기조절방사선치료 플루언스 지도에 대해, 다양한 크기 - 0.5$\times$0.5, 1.0$\times$1.0, $1.5\times$1.5, 2.0$\times$2.0, 3.0$\times$3.0, 4.0$\times$4.0, 5.0$\times$5.0 $ extrm{cm}^2$ - 의 정사각형 패턴들을 설계하였고, Leaf sequence 는 step-and-shoot 빔 전달 방법을 이용하였다. 인접 조각들 사이의 세기 비율은 0.2, 0.4, 0.6, 0.8, 1.0로 하였고, 표적 움직임은 범위가 0.5-2.0 cm인 사인곡선 형태로 가정하였다. 움직임 묘사를 위해 동적 leaf 의 움직임이 표적의 움직임 을 반영하도록 계산되었고 움직임의 효과를 분석하기 위해 필름선량측정을 수행하였다. 결과 : 인접 조각의 세기 비율은 모든 경우에서 저하되었고, 호흡 진폭의 반보다 작은 조각 크기에 대한 선량분포는 임상적으로 유의할만큼 저하된 세기 지도를 보였다. 조각에 대해 방사선 조사시간의 두 호흡주기이상에 대해서는, 표적 마진 주위의 선량분포가 통상적인 정지 조사면에서와 같았다. 결론 : 플루언스 지도에서 세기조절방사선치료 조각의 최소 크기는 치료중 장기 움직임을 고려한 후 선택되어야 한다. 조각에 대한 방사선 조사시간의 두 호흡주기이상에 대해서는, 표적 마진을 기존의 정지 조사면과 같게 정의할 수 있었다.

• The Journal of Korean Academy of Prosthodontics
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• v.59 no.4
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• pp.379-394
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• 2021

Purpose. In our previous studies, application of trichloroacetic acid (TCA) to gingival fibroblasts or to canine palatal soft tissue was verified to alter the expression of several genes responsible for cell cycle progression. In order to confirm this effect in a system allowing sequential release of TCA and epidermal growth factor (EGF), expression of various cell cycle genes following the application of the agents, using hydrophobically modified glycol chitosan (HGC)-based nano-controlled release system, was explored in this study. Materials and methods. HGC-based nano-controlled release system was developed followed by loading TCA and EGF. The groups were defined as the control (CON); TCA-loaded nano-controlled release system (EXP1); TCA- and EGF- individually loaded nano-controlled release system (EXP2). At 24- and 48 hr culture, expression of 37 cell cycle genes was analyzed in human gingival fibroblasts. Correlations and the influential genes were also analyzed. Results. Numerous genes such as cyclins (CCNDs), cell division cycles (CDCs), cyclin-dependent kinases (CDKs), E2F transcription factors (E2Fs), extracellular signal-regulated kinases (ERKs) and other cell cycle genes were significantly up-regulated in EXP1 and EXP2. Also, cell cycle arrest genes of E2F4, E2F5, and GADD45G were up-regulated but another cell cycle arrest gene SMAD4 was down-regulated. From the multiple regression analysis, CCNA2, CDK4, and ANAPC4 were determined as the most influential factors on the expression of ERK genes. Conclusion. Application of TCA and EGF, using the HGC-based nano-controlled sequential release system significantly up-regulated various cell cycle progression genes, leading to the possibility of regenerating oral soft tissue via application of the proposed system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.7 no.5
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• pp.866-874
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• 2006

This paper proposes a new Dynamic Voltage Scaling(DVS) algorithm to achieve low-power scheduling of aperiodic hard real-time tasks. Aperiodic tasks schedulingcannot be applied to the conventional DVS algorithm and result in consuming energy more than periodic tasks because they have no period, non predictable worst case execution time, and release time. In this paper, we defined Virtual Periodic Task Set(VTS) which has constant period and worst case execution time, and released aperiodic tasks are assigned to this VTS. The period and worst case execution time of the virtual task can be obtained by calculating task utilization rate of both periodic and aperiodic tasks. The proposed DVS algorithm scales the frequency of both periodic and aperiodic tasks in VTS. Simulation results show that the energy consumption of the proposed algorithm is reduced by 11% over the conventional DVS algorithm for only periodic task.

• Korean Journal of Soil Science and Fertilizer
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• v.40 no.5
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• pp.354-363
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• 2007

In order to investigate the optimum rate and interval of silicate fertilizer application for rice cultivation, Chucheong byeo variety, one of commonly cultivated rice cultivar in Korea was planted on two different wetland rice soils located on Hwaseong-si from 2002 to 2005; Jisan series(a member of the fine loamy, mixed, mesic family of Fluvaquentic Endoaquepts), known as "Productive Paddy Soil", without any conspicuous limiting factor, and Seokcheon series (a member of the coarse loamy, mixed, nonacid, mesic family of Fluvaquentic Endoaquetps), known as "Sandy Paddy Soil", sandiness being major limiting factor. There were three rate treatments of silicate fertilizer application; the amount of silicate fertilizers needed to adjust the available soil silicate contents to 130, 200, and $270mg\;kg^{-1}$ was applied, in the first year only. There was an additional plot; applying the amount of silicate fertilizer needed to adjust soil available silicate to 130 ppm every year, which would serve as the base for the evaluation of residual effects of silicate fertilizers in the plots where different rates of silicate fertilizer were applied. From the yield data in first year, it was found that optimum available silica in the soil are $154mg\;kg^{-1$ and $160mg\;kg^{-1}$, in Jisan and Seogcheon soils, respectably. The duration of residual effects of silicate fertilizer was different depending upon the amount of applied silicate fertilizers and the soils. The higher the application rate, the residual effect lasted longer, and the residual effect was lasted longer in Jisan(clay loam) soil than in Seogcheon(sandy loam) soil. During four years, sum of the rate of contribution to increase available soil silica of applied silicate fertilizer in different soils ranged 18.6% and 24.1% in Jisan soil and Seogcheon soil, respectively. This may suggest that much portion of applied silicate would be either lost from the soil or remain in the soil as insoluble form. This deserves further study.

• Journal of Life Science
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• v.23 no.8
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• pp.1064-1072
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• 2013

Circadian rhythm is controlled by hormonal oscillations governing the physiology of all living organisms. In mammals, the main function of the pineal gland is to transform the circadian rhythm generated in the hypothalamic suprachiasmatic nucleus into rhythmic signals of circulating melatonin characterized by a largely nocturnal increase that closely reflects the duration of night time. The pineal gland has lost direct photosensitivity, but responds to light via multi-synaptic pathways that include a subset of retinal ganglion cells. Rhythmic control is achieved through a tight coupling between environmental lighting and arylalkylamine-N-acetyltransferase (AANAT) expression, which is the rhythm-controlling enzyme in melatonin synthesis. Previous studies on the nocturnal expression of AANAT protein have described transcriptional, post-transcriptional, and post-translational regulatory mechanisms. Molecular mechanisms for dependent AANAT expression provide novel aspects for melatonin's circadian rhythmicity. Extensive animal research has linked pineal melatonin for the expression of seasonal rhythmicity in many mammalian species to the modulation of circadian rhythms and to sleep regulation. It has value in treating various circadian rhythm disorders, such as jet lag or shift-work sleep disorders. Melatonin, also, in a broad range of effects with a significant regulation influences many of the body's physiological functions. In addition, this hormone is known to influence reproductive, cardiovascular, and immunological regulation as well as psychiatric disorders.

• Proceedings of the Korean Society for Bio-Environment Control Conference
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• 2006.05a
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• pp.160-163
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• 2006