• Journal of Korean Academy of Nursing
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• v.18 no.2
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• pp.211-219
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• 1988

운동학습이론인 감각운동 통합이론을 본 연구의 개념적 틀로하여 한방병원에 입원한 뇌졸중 환자 중 구강인두 기능이 저하된 환자를 대상으로 감각운동자극이 구강인두 기능에 미치는 효과를 조사하기 위하여 1988년 3월초부터 5월 중순까지 예비실험 연구하였다. 감각운동자극을 주기 전에 구강인두기능을 시정하고 대상자 전원에게 저하된 구강인두기능에 따라 감각운동자극을 선택하여 하루 3번 매식후 30분전에 주었으며, 이를 일주일 동안 계속하였다. 일주일 후 다시 구강인두기능을 측정하여 자극을 주기전, 후의 기능정도를 paired t-test로 비교 분석하였으며 다음과 같은 성적을 얻었다. 1. “자극을 주기 전보다 준 후에 머리와 목운동 조절점수가 높을 것이다”라는 제1가설은 지지되었다(t＝-2.71, df＝5, p＝.042). 2. “자극을 주기 전보다 준 후에 씹는 능력이 증가되었으나, 통계적으로는 유의하지 않았다(t＝-2.00, df＝5, p＝.102). 3. “자극을 주기 전보다 준 후에 입술운동의 조절점수는 높을 것이다”라는 제3가설은 지지되었다(t＝-4.77, df＝5, p＝.005). 4. “자극을 주기 전보다 준 후에 혀 운동 조절점수가 높을 것이다”라는 제4가설은 지지되었다(t＝-3.61, df＝5, p＝.015). 5. 자극을 주기 전보다 준 후에 연하능력이 증가되었으나 통계적으로는 유의하지 않았다(t＝-2.24, df＝5, p＝.076). 이상의 결과로 감각운동자극은 연하장애환자의 구강인두기능을 증진시키는데 효과적인 방법이라고 할 수 있다.

• The Korean Journal of Zoology
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• v.35 no.4
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• pp.509-517
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• 1992

LiCl (0.047 M)은 Goldhamster의 활동주기 (T)를 평균 1.6시간 연장시키고, 동물 중 20%엑서 단축되는 것으로도 관찰되었다. 1시간 통안의 빛자극(75 Lux)에 의해 주기현상 시점 변화가 나타나는 데 LICI에 의해서 0.3 h 더욱 delav되었고 advance 현상은 1.5 h 감소되었으며 delay엔h advance 전환시기는 1시간 늦게 나타났다. 반면에 7 Lux의 빛 자극에서는 delay가 2.4시간으로 더 증가되었으며 advance 현상은 2.6시간으로 저하되었고, 30분 늦게 delay에서 advance로 전환되었다. subjective day 동안에는 빛자극에 의한 LiCl 효과가 전혀 보이지 않았다. Phase-Response-Curve(PRC)는 Circadian Time에서 delay-advance로 전환되는 mid-subjective night에 점진적으로 변화되는 weak phase curve로 형성되었다. 이 PRC에서 Li이 빛에 대한 민감성을 둔화시키는 효과를 볼 수 있다.

• Child Health Nursing Research
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• v.10 no.4
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• pp.451-459
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• 2004

Purpose:　The purpose of this study is to identify how regular stimulation affects apnea of a premature infant. Method: This study was used a within-subjects design with repeated measure using GEE (General Estimating Equation) and had been conducted from July 1, 2003 to March 12, 2004. The subjects consisted of 11 apneic premature infants who had showed apnea more than twice for 12 hours. A regularly vibrating test lung was provided to the subjects to find how regular stimulation affects apnea. Result: From the result of regular stimulation for apneic premature infants, both the lowest SaO2 and the lowest heart rate at experimental period were found to be increased significantly. However, the decreased frequency of the apnea cases was not statistically effective. Conclusion: These findings indicate that regular stimulation for apneic premature infants could be effective on increasing both SaO2 and heart rate. Therefore, we suggest regular stimulation to be used clinically to heal apnea of premature infants.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.10a
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• pp.17-17
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• 2003

• Proceedings of the KOSOMBE Conference
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• v.1994 no.05
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• pp.69-71
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• 1994

1Hz에서 20Hz까지의 단속 주파수를 지닌 청각자극을 가해 얻은 EEG신호에서 자극에 따른 신호의 정성적이고 정량적인 특성을 카오스 분석방법을 통해 밝혔다. 먼저, 뇌전위 신호에 전반적으로 나타나는 일반적인 카오스 특징(fractal mechanism, 1/f frequency spectrum, positive lyapunov exponent등등)이 확인되어졌다. 유발전위에 대해서는 자극의 주파수에 따른 주기 배증을 경유한 카오스로 가는 길(route to chaos)과 2차원 pseudo-phase portrait의 뿌앙까레 단면에서의 기하학적 모양(topological property)의 변화가 관찰되어졌고, 자발전위가 포함된 유발전위에 대해서는 적절한 bases를 지닌 3차원 phase space에서 기이한 끌개(chaotic attractor)가, 유발전위의 정보를 지닌채 보여졌다. 끝으로 자극 주파수(단속 주파수와 반송 주파수) 변화와 측정이 이루어진 머리표면에서의 공간적 위치에 따른, lyapunov exponent값 변화가 의미있게 해석되어졌다. 이 결과는 무질서하게 보이는 뇌전위신호에서 주어진 청각자극에 대한 정보를 얻는 새로운 방법을 제시하게 된다.

• Clinical and Experimental Reproductive Medicine
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• v.36 no.1
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• pp.63-70
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• 2009

Objective: This study was performed to investigate the effectiveness of minimal stimulation using rhFSH and GnRH antagonist compared with GnRH antagonist multidose protocol (MDP) in IVF treated patients with aged 40 and above. Methods: Seventy-five patients with aged 40 and above were equally randomized to minimal stimulation group (n=37) or GnRH antagonist MDP group (n=38). For minimal stimulation group, ultrasound monitoring was started on cycle day 7 or 8. Daily injections of 0.25 mg cetrorelix together with 150 IU rhFSH were started from the day at 13${\sim}$14 mm of a leading follicle diameter. For GnRH antagonist MDP group, daily injections of 225 IU rhFSH were initiated from cycle day 2 and GnRH antagonist was started at a dose of 0.25 mg/day on rhFSH stimulation day 6 or the day at 13${\sim}$14 mm of leading follicle diameter. In both groups, transvaginal ultrasound-guided oocyte retrieval was performed. According to cleavage and morphologic characteristics of embryos, embryos were transferred 3 to 5 days after oocyte retrieval. Results: There were no differences in patients' characteristics and cycle cancellation rate between the two groups. Total dose and duration of rhFSH used were significantly fewer and shorter in minimal stimulation group than those in GnRH antagonist MDP group. The numbers of oocytes retrieved, mature oocytes and transferred embryos were also lower in minimal stimulation group. However, there were no significant differences in the clinical pregnancy rate and miscarriage rate between the two groups. Conclusions: This study demonstrates that minimal stimulation protocol provides comparable pregnancy rates to GnRH antagonist MDP with fewer dose and days of rhFSH used, and thus can be a cost-effective alternative in women aged 40 and above.

• Korean Institute of Interior Design Journal
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• no.21
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• pp.26-32
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• 1999

This study is intended to explore the tendency of interior design which have sustained the periodic changes throughout the history. After analysis of changes in interior design from 1920's early modernism to nowadays, the conclusion is as follows. In view of the human psychology, the main trend of consistent periodic changes is the revolutionary change of tension and relaxation, and the pursuit of such a change in design is rooted in the human basic need to get the vital energy through stimuli by giving and taking the variety in the public society.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.9
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• pp.4045-4052
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• 2012

The aim of this single blind intervation study was to compare the analgesic effects of transcutaneous electrical nerve stimulation (TENS) and interferential currents (IFC) on cold-induced pain in healthy volunteers. Sixteen subjects completed six cycles of the cold-induced pain test. During each cycle pain threshold was recorded as the time from immersion of the subject is hand in cold water to the first sensation of pain and pain intensity and unpleasantness ratings were recorded using visual analogue scales. Subjects were randomly allocated to receive each 50 Hz-TENS, 50 Hz-IFC, 100 Hz-TENS and 100 Hz-IFC. Statistical analysis showed that four interventions elevated the cold pain threshold significantly and the difference between interventions was not simply significant. But, no significant differences were identified in pain intensity and unpleasantness ratings. We conclude that there were no differences in the analgesic effects of the four interventions under the present experimental conditions. But, 50 Hz-IFC has been shown to be more comfortable than other interventions.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2007.04a
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• pp.58-62
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• 2007

인간이 생성한 음성, 표정 영상, 문장 등으로부터 인간의 감정 상태를 인식하는 연구와 함께, 인간의 감정을 모방하여 다양한 외부 자극으로 감정을 생성하는 인공 감정(Artificial Emotion)에 관한 연구가 이루어지고 있다. 그러나 기존의 인공 감정 연구는 외부 감정 자극에 대한 감정 변화 상태를 선형적, 지수적으로 변화시킴으로써 감정 상태가 급격하게 변하는 형태를 보인다. 본 논문에서는 외부 감정 자극의 강도와 빈도뿐만 아니라 자극의 반복 주기를 감정 상태에 반영하고, 시간에 따른 감정의 변화를 Sigmoid 곡선 형태로 표현하는 감정 생성 모델을 제안한다. 그리고 기존의 감정 자극에 대한 회상(recollection)을 통해 외부 감정 자극이 없는 상황에서도 감정을 생성할 수 있는 인공 감정 시스템을 제안한다.

• Clinical and Experimental Reproductive Medicine
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• v.7 no.1_2
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• pp.3-10
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• 1980

Pituitary gonadotropes, as target cells, exhibit cyclic changes in terms of LH and FSH release in synchrony with the estradiol levels. The ultimate release is determined by the relative size of the two pools of gonadotropins, which is regulated by the two controllers: LH-RH and estradiol. LH-RH appears to serve as a primary drive on the gonadotrope, stimulating gonadotropin synthesis, storage, and release. Estradiol amplifies the action of LH-RH and induces the development of a self-priming effect of LH-RH except that it impedes LH-RH mediated gonadotropin release. Negative and positive feedback action of estradiol is revealed to operate by different mechanisms. The pituitary capacity increases severalfold from early to late follicular phase, which is considered to be prerequisite for the development of mid-cycle surge. CNS-hypothalamic dopamine, norepinephrine, and prostaglandins, as well as LH-RH, are involved in the negative and positive feedback effects of estradiol. The possible mechanisms in the triggering of LH-RH release for the initiation of midcycle LH-RH surge are considered.