• Journal of The Korean Society of Inherited Metabolic disease
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• v.15 no.3
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• pp.165-170
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• 2015

Ornithine transcarbamylase (OTC) deficiency is a rare X-linked genetic disorder of urea synthesis in newborns. It is the most common urea cycle disorder and leads to elevated levels of ammonia in the blood. Excessive ammonia can cause various symptoms, including vomiting, lethargy, and coma. Boys have a more serious form of OTC deficiency than girls. If not treated immediately, severe OTC deficiency can lead to neurologic abnormalities, hyperammonemic coma, and death. Because late-onset OTC deficiency, which is more common in girls, presents mild symptoms, it is easy to miss diagnosis and prompt treatment. We describe an 11-month-old girl who presented periodic vomiting, intermittent lethargy, and seizure. She was diagnosed with OTC deficiency by elevated serum ammonia and urine orotic acid levels. Genetic analysis of the OTC gene revealed a missense mutation in exon 5 (c.418G>C). We reported an experience of exact diagnosis and successful treatment of late-onset OTC deficiency in our patient.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.41 no.7
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• pp.569-576
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• 2013

The Airworthiness Certification from the government has an increasingly important role due to the dramatic growth of military aircraft development industry. It is a mandatory process of qualifying the flight safety within the aircraft's operational boundaries throughout its life cycle. The introduction of airworthiness certification has resulted in development paradigm shift from one requirement for one consumer need to the common requirement for many needs. This research paper provide the refinement of airworthiness certification criteria related to the flight control law and the verification methods which comply with its criteria.

• Bulletin of the Society of Naval Architects of Korea
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• v.33 no.3
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• pp.40-46
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• 1996

함정설계지원시스템이란 함정 설계의 목표를 효율적으로 달성하기 위한 제반 기술적인 수단과 이들의 운용체제로, 함정 고유의 설계기술과 결합한 컴퓨터 이용기술의 집합체로 정의할 수 있다. 함정설계 및 건조에 있어서 컴퓨터기술의 이용은 아나로그 컴퓨터가 실용화되면서부터 활발하게 추진되기 시작하였다. 초기에는 주로 진동해석 및 제어시스템과 같은 여러가지 동적인 문제의 해결에 촛점이 맞추어져 왔다. 1960년대 초 컴퓨터 기술이 설계 분야에 이용되면서 선박의 설계 및 건조의 전 과정에 적용될 범용 컴퓨터 프로그램을 개발하기 위한 노력이 본격화되었으며, CAD tool이 상용화되기 전까지는 간단한 도형처리 기능을 포함한 특정 공학 해석을 신속하게 수행하기 위한 프로그램들이 개발, 사용되어 왔다. 컴퓨터 관련 기술이 발전함에 따라 함정설계지원시스템도 종래의 부분적인 설계업무의 자동화에서 함정의 획득(acquistion) 및 전 수명주기의 지원(life-cycle support) 과정에서의 생산성 향상, 품질향상 및 예산절감을 위한 수단으로 확대 발전되어 왔으며 최근에는 (CALS(Continuous Acquistion and Life-cycle Support)라는 새로운 문제로 정착되고 있다. 본 고에서는 21세기 대양해군을 지향하는 우리나라 해군력의 기본이 되는 함정의 설계, 건조 및 운용 지원분야의 획기적인 발전을 위해, 그 핵심적인 수단이 ㅗ딜 함정설계지원시스템의 개발동향에 대해 이 분야의 기술을 주도하고 있는 미 해군의 사례를 중심으로 살펴보고 현 단계에서 우리 해군이 추진가능한 몇가지 과제에 대해 제안하였다.

• Korean Journal of Optics and Photonics
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• v.14 no.3
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• pp.266-271
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• 2003

The reflectance spectrum of optical films thicker than a few microns shows an intensity oscillation due to interference. Since the spectral period of the oscillation is inversely related to film thickness, the thickness of an optical film can be determined from the spectral frequency of the oscillation. For rapid data processing, the spectral frequency is obtained by use of a Fast Fourier Transformation technique. The conventional method of applying a Fast Fourier Transformation to the reflectance spectrum versus photon energy is modified so as to clear the ambiguity in choosing the proper effective refractive index value and to prevent the broadening of the Fourier transformed peak due to the refractive index dispersion. This technique of modified Fast Fourier Transformation is suggested by the authors for the first time to their knowledge. From the analysis of the calculated reflectance spectrum of a 30-${\mu}{\textrm}{m}$-thick dielectric film. it is shown to improve the accuracy in determining film thickness by a great amount. The improved accuracy of the modified Fast Fourier Transformation is also confirmed from the analysis of the reflectance spectra of a sample with 80-${\mu}{\textrm}{m}$-thick cover layer and 13-${\mu}{\textrm}{m}$-thick spacer layer on a PC substrate.

• The Journal of the Acoustical Society of Korea
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• v.33 no.3
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• pp.191-199
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• 2014

Wave reflection and transmission characteristics in waveguides are an important issue in many engineering applications. A combined spectral element and finite element (SE/FE) method is used to investigate the effects of local non-uniformities but limited at relatively low frequencies because the SE is formulated by using a beam theory. For higher frequency applications, a method named a combined spectral super element and finite element (SSE/FE) method was presented recently, replacing spectral elements with spectral super elements. This SSE/FE approach requires a long computing time due to the coupling of SSE and FE matrices. If a local non-uniformity has a uniform cross-section along its short length, the FE part could be further replaced by SSE, which improves performance of the combined SSE/FE method in terms of the modeling effort and computing time. In this paper SSEs are combined to investigate the characteristics of waves propagating along waveguides possessing geometric non-uniformities. Two models are regarded: a rail with a local defect and a periodically ribbed plate. In the case of the rail example, firstly, the results predicted by a combined SSE/FE method are compared with those from the combined SSEs in order to justify that the combined SSEs work properly. Then the SSEs are applied to a ribbed plate which has periodically repeated non-uniformities along its length. For the ribbed plate, the propagation characteristics are investigated in terms of the propagation constant.

• The Korean Journal of Quaternary Research
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• v.33 no.1_2
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• pp.37-48
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• 2021

The cold surge is an important extreme weather in East Asia during winter, and is largely affected by behavior of the Siberian high Arctic Oscillation, which represents undulation of large-scale pressure pattern in the Arctic region. Recent studies also revealed that the synoptic low pressure system developing in the eastern boundary of the Asian continent is sensitive to sea surface temperature (SST) and plays an important role in strengthening the cold advection over the Korean Peninsula during cold surges. In this study, we analyzed the Arctic Oscillation affecting the large-scale background of cold surge in East Asia, and the sea surface temperature in the coast of East Asia is examined focusing on its role on synoptic low-inducing cold advection. For the analysis, the days with the bottom 3% of the average daily temperature, measured at five surface stations in Korean Peninsula during 49 years (1969/70-2017/18), were used for the cold surge cases. During the negative phase of the Arctic Oscillation, a strong trough is observed over East Asia, and the inflow of cold air from the polar region is strengthened, which lead to frequent cold surges. In addition, anomalously high SST in the eastern coast of Asia increases sensible and latent heat release from the ocean, therefore, it enlarges the likelihood of synoptic low-inducing extreme cold surges.

• Proceedings of the Korean Vacuum Society Conference
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• 1999.07a
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• pp.44-44
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• 1999

저진공(1 kPa~ 100 kPa)은 대기압 측정, 비행고도, 기체의 온도 측정, 질량의 부력 보정, 레이저의 굴절률 측정등에 사용되는 영역으로 과학적 중요성을 갖고 있다. 또한 대기압 이상의 압력 측정과 고진공 측정의 경계적 역할도 수행하고 있어 압력 표준기의 국제 비교에 필수적으로 권장되는 역역이다. 이 영역에 주로 사용되는 압력 표준기는 수은 압력계(Mercury manometer)와 분동식 압력계(Deadweight piston gauge or Pressure)가 있다. 이들은 이동이 불편하거나 불가능하므로 표준기의 국제 비교에 사용되는 전달 표준기로는 보다 이동이 간편한 탄성 압력계인 CDG(Capacitance diaphragm Gauge)가 있다. 이 게이지는 반도체 산업의 공정 제어용으로도 많이 사용되고 있다. 그러나 게이지와 함께 사용되는 컨트롤러의 부피가 크고 무거우며 영점 이동이 커서 측정때 마다 재조정하여야 하는 단점이 있다. 본 논문에서는 이 같은 단점을 극복하기 위해 수정빔 진동형 진공 센서를 잔달 표준기로 사용하는 것에 대한 연구를 수행하였다. 수정빔 진동형 압력 센서는 수정빔으 공진주파수가 스트레인에 비례하는 것을 이용하여 제작된 센서로 주로 대기압 이상의 고압 측정에 많이 사용되고 있다. 먼저 수정빔의 압력과 주파수간의 관계를 측정하고 또한 내장된 수정 온도센서의 공진 주파수를 측정하여 온도 보상을 위한 자료로 사용하였다. 규격에 나와 있는 수정빔의 기하학적 형상으로부터 거동에 관한 이론 모델식을 구하고 압력교정 자료로부터 얻어진 데이터를 이 식과 비교 분석하여 적합한 특성식과 인자를 구하였으며 게이지의 불확도를 추정하였다.모델은 길이가 유한한 0-차원 실린더 모델로 가정하였고, 이에 대한 기하학적 성질 및 열역학적 성질은 유효계수를 고려하여 산출하였다. 진공용기 이중 벽 내부로 흐르는 질소가스의 유량과 온도의 계산은 진공용기 내벽과 외벽을 각각 독립적인 열전달 요소로 가정하여 구성한 모델을 이용하였다. 전체 해석에서 각 열전달 요소의 비열 값은 온도에 따라 변화하는 비열의 특성을 반영하였으며. 진공용기와 플라즈마 대향 부품의 방사율(emissivity)은 앞서 가정했던 각 온도 상승 곡선에 대해서 각각 0.1, 0.2, 1.3의 경우를 가정하여 계산하였다. 직선적으로 증가하는 온도 상승 곡선중 2$0^{\circ}C$/hr의 온도상승율을 갖는 경우가 다른 베이킹 시나리오 모델에 비해 효과적이라 생각되며 초대 필요 공급열량은 200kW 정도로 산출되었다. 실질적인 수치를 얻기 위해 보다 고차원 모델로의 해석이 필요하리라 생각된다. 끝으로 장기적인 관점에서 KSTAR 장치의 베이킹 계획도 살펴본다.습파라미터와 더불어, 본 연구에서 새롭게 제시된 주기분할층의 파라미터들이 모형의 학습성과를 높이기 위해 함께 고려된다. 한편, 이러한 학습과정에서 추가적으로 고려해야 할 파라미터 갯수가 증가함에 따라서, 본 모델의 학습성과가 local minimum에 빠지는 문제점이 발생될 수 있다. 즉, 웨이블릿분석과 인공신경망모형을 모두 전역적으로 최적화시켜야 하는 문제가 발생한다. 본 연구에서는 이 문제를 해결하기 위해서, 최근 local minimum의 가능성을 최소화하여 전역적인 학습성과를 높여 주는 인공지능기법으로서 유전자알고리즘기법을 본 연구이 통합모델에 반영하였다. 이에 대한 실

• Korean Journal of Remote Sensing
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• v.22 no.6
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• pp.519-531
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• 2006

Sea surface height (SSH) around fe Korean Peninsula was investigated as a rising rate of $3.89mm\;yr^{-1}$ on the average from 1993 to 2005, which is 1.3 times higher rising rate, compared to the world ocean. In the present study, to investigate SSH changes in regional sections of the East Sea, the Yellow Sea, the South Sea, and the Korea Strait, DT-MSLA (Delayed Time-Maps of Sea Level Anomalies) with multi-satellite data (Topex/Poseidon, Jason-1, ERS, Envisat), provided by AVISO (Archiving, Validation and Interpretation of Satellite Oceanographic data), was used. The periodicity in interannual variability was dominant for $4\sim5$ year in summer, and 3 year in winter as well as an increasing trend. The amplitude and phase for the annual and semi-annual mode in SSH and SST were investigated with harmonic analysis. The geographical distribution of amplitudes for comparison of SSH and SST are slightly reverse in southwest-northeast tilted direction. The monthly SST and SSH is highly correlated correlation coefficient about 0.7 with lag of one or two months over the East Sea and the South Sea during June-August. These results suggest that the Kuroshio stream is dominant during summer over these regions.

• Tunnel and Underground Space
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• v.19 no.6
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• pp.490-497
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• 2009

The horizontal and vertical response spectra using the observed ground motion from the recent 5 macro earthquakes were analysed and then were compared to both the seismic design response spectra(Reg Guide 1.60), applied to the domestic nuclear power plants, and the Korean Standard Design Response Spectrum for general structures and buildings(1997). 74 horizontal and 89 vertical observed ground motions, without considering soil types, were used for normalization with respect to the peak acceleration value of each ground motion. The results showed that the horizontal MPOSD(Mean Plus One Sigma Standard Deviation) response spectra revealed much higher values for the whole frequency bands above 1 Hz than Reg. Guide(1.60). For the vertical response spectra, the results showed slightly higher than just between 7 and 8 Hz frequency band. The results were also compared to the Korean Standard Response Spectrum for the 3 different soil types and showed that the horizontal MPOSD response spectra revealed much higher values for the whole periods below 2 second(0.5 Hz) than those of SE soil type. The vertical response spectra showed similar to the values of the Korean Standard Response Spectrum of SD soil type. These spectral values dependent on frequency could be related to characteristics of the domestic crustal attenuation and the effect of each site amplification. However, through the qualitative improvements and quantitative enhancement of the observed ground motions, the conservation of horizontal seismic design response spectrum should be considered more significantly for the whole frequency bands above the 1 Hz.

• Journal of the Earthquake Engineering Society of Korea
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• v.1 no.2
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• pp.17-29
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• 1997

Single-mode spectral analysis method is usually applied to a small-scale bridges with the simple geometric shape and uses only fundamental period to estimate the elastic earthquake forces and the displacements of the substructure. On the other hand, multi-mode spectral analysis method may be used instead if the possibilities of potential damage are developed when considering significance, scale, and geometric shape of briages. Since the dynamic responses of bridge can be significantly different depending on the modeling techniques for the restraint and support conditions etc, it may be misled to the unexpected results. In this study the dynamic analysis program which can model and analyze the bridge as a two- or three-dimensional framed structure is developed and verified with the results of other reliable program. Using this program together with the post processor, the designer can easily and readily obtain the reponses(moments, base shears, and displacements)of bridges necessary to design purpose. And further from the analysis results according to the variations of type, scale, and restraint and supprot conditions of bridges including sectional properties, applications of the effective and desirable seismic design are presented.