• Journal of Plant Biotechnology
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• v.29 no.4
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• pp.265-275
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• 2002

Flavonoid biosynthesis is one of the most extensively studied areas in the secondary metabolism. Due to the study of flavonoid metabolism in diverse plant system, the pathways become the best characterized secondary metabolites and can be excellent targets for metabolic engineering. These flavonoid-derived secondary metabolites have been considerably divergent functional roles: floral pigment, anticancer, antiviral, antitoxin, and hepatoprotective. Three species have been significant for elucidating the flavonoid metabolism and isolating the genes controlling the flavonoid genes: maize (Zea mays), snapdragon (Antirrhinum majus) and petunia (Prtunia hybrida). Recently, many genes involved in biosynthesis of flavonoid have been isolated and characterized using mutation and recombinant DNA technologies including transposon tagging and T-DNA tagging which are novel approaches for the discovery of uncharacterized genes. Metabolic engineering of flavonoid biosynthesis was approached by sense or antisense manipulation of the genes related with flavonoid pathway, or by modified expression of regulatory genes. So, the use of a variety of experimental tools and metabolic engineering facilitated the characterization of the flavonoid metabolism. Here we review recent progresses in flavonoid metabolism: confirmation of genes, metabolic engineering, and applications in the industrial use.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.6
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• pp.205-220
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• 2018

Software defect prediction is helpful for allocating valuable project resources effectively for software quality assurance activities thanks to focusing on the identified fault-prone modules. If historical data collected within a company is sufficient, a Within-Project Defect Prediction (WPDP) can be utilized for accurate fault-prone module prediction. In case a company does not maintain historical data, it may be helpful to build a classifier towards predicting comprehensible fault prediction based on Cross-Project Defect Prediction (CPDP). Since CPDP employs different project data collected from other organization to build a classifier, the main obstacle to build an accurate classifier is that distributions between source and target projects are not similar. To address the problem, because it is crucial to identify effective similarity measure techniques to obtain high performance for CPDP, In this paper, we aim to identify them. We compare various similarity measure techniques. The effectiveness of similarity weights calculated by those similarity measure techniques are evaluated. The results are verified using the statistical significance test and the effect size test. The results show k-Nearest Neighbor (k-NN), LOcal Correlation Integral (LOCI), and Range methods are the top three performers. The experimental results show that predictive performances using the three methods are comparable to those of WPDP.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2007.11a
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• pp.1019-1022
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• 2007

Recent construction projects are becoming larger, more complex and higher rising. Accordingly, necessity of the VE is emphasized as more suitable for expense, function and quality. However, the VE is not functional because of difficulty of application process or of the methods in use in the field of construction. One of the alternative is to introduce the incentive system to activate the VE in the field of construction. By using the incentive system, employers can reduce the relevant project's prime cost and builders will maximize profit creation. In domestic case, they presented the systematic support policy 'Technical development compensation system' which is similar to the 1992 American's VE incentive system about builder's technical development effort but the result was not positive. This study investigates both domestic and other country's construction VE incentive system and reported problems in the construction VE incentive system to executives and construction VE experts. From this survey, conclusions were drawn about problems in the domestic construction VE incentive system's similarity system: 'Insufficiency of the construction VE incentive's article and standards', 'Insufficiency of the appraiser of the construction VE and of the full charge department' etc. I had interviews with the experts of the construction VE which were based on the above-mentioned problems and then presented 'Improvement of the construction VE's incentive system relevant law and system', 'Construction VE experts and construction formation' etc. for ways to bring acceptance of the construction VE in the construction industry.

• Journal of The Korean Association For Science Education
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• v.35 no.1
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• pp.73-84
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• 2015

In this research, two careers connectable with the contents of the curriculum of fifth to sixth grade elementary school students were selected among other promising future careers in biotechnology and medical engineering fields. 'Design-based promising future career STEAM program' was developed and its validity and effectiveness were verified. Reflecting recent issues, and complying with the STEAM standard (frame) instructional materials were developed through group deliberations for nine months, based on the achievement standards through an analysis of subject curriculum revised in 2009. This was prepared so that students are able to experience biotechnology and medical engineering related careers in a simulational form emphasized with creative design to make them prefer natural sciences and engineering careers and draw their interests and recognition of the relevant careers under the two disciplines. As a result of such application to STEAM Leader School students at the verification stage of the program, the contents and level of the program were verified suitable, receiving favorable reviews. And as a result of applying the developed program on other elementary school students, it was discovered that significant improvements were found in their career consciousness. Through this research, it was suggested that there is a need for a simplification of the curriculum content standards, a provision of 'standard for integration,' development of teachers' ability in reconstituting or organizing the STEAM and proceeding classes, continuous long-term support to see the effects of a policy or a program, and a reinforcement of career education integrated in the curriculum.

• Annual Conference on Human and Language Technology
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• 1994.11a
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• pp.57-63
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• 1994

인간의 정보처리 과정의 특성을 알아보기 위하여 반구별로 색채와 단어의 처리과정을 분석하였다. 단어와 색깔이라는 두가지 자극 속성이 있는 한 개의 자극에 대하여 각 자극 속성에 대한 판단과정을 반응키를 이용하여 반구별로 알아보았다. 단어에 대한 판단과 색깔에 대한 판단을 반구별로 분석한 결과, 색깔처리나 단어처리에 있어서 반구간 비대칭성은 나타나지 않았으나 색깔에 대한 판단이 단어에 대한 판단보다 신속하게 이루어지는 것으로 나타나 색채가 단어보다 기초적인 자극 속성임을 확인하였다. 단어와 색깔이라는 두가지 자극 속성을 이용한 경우에 한가지 자극속성을 처리할 때 다른 자극속성이 자동적으로 영향을 주는 것으로 나타났으나 그 정도에 있어서 반구간의 차이는 없었다. 그러나 색채가 단어처리를 간섭하는 정도가 단어가 색채처리를 간섭하는 정도보다 큰 것으로 나타나 기존의 스트룹 연구결과들과는 상반되는 결과를 얻었는데 이는 과제의 특성이라는 측면으로 기술되었다. 단어 처리에서 반구간 차이가 발견되지 않은 것은 한글의 시각적 특성과 관련지어 논의되었다. 자극의 한 속성이 자동적으로 다른 속성에 영향을 주지만 그 효과의 크기도 반구별로 차이가 없다는 것은 이전의 반구별 스트룹 효과를 알아본 연구들과 상반되는 결과이다. 따라서 자극속성이 상호영향을 줄 수 있는 좀더 일반적인 상황에서는 한 자극 속성이 다른 자극 속성의 처리에 자동적으로 영향을 주는 효과에서 반구 비대칭성이 발견되지 않으며 스트룹 효과는 두 자극 속성의 관계가 밀접한 특별한 경우에 나타나는 반구비대칭성 효과인 것으로 논의되었다.양 발생과 유의적으로 상관관계가 있었다. 본 연구의 결과는 phenol의 종류에 상관없이 식이 phenol에 조직의 항산화(산화억제)를 통해 암 예방(cancer prevention)에 영향을 미친다는 것을 제시해준다.물을 첨가하여 물내리기를 한 후 김이 오른 후 물내린 쌀가루에 15% 이상의 설탕을 첨가하여 20분간 쪄서 만든 백설기가 가장 바람직하다는 것을 알 수 있었다. 이 실험 중 가장 중요한 조건은 첨가하는 물의 양이 10%이며 첨가하는 당이 설탕일 경우는 김이 오른 후 설탕을 섞어 바로 쪄야 하며 설탕의 양이 15% 이상이라는 것이다. 이 조건은 대체적으로 hardness, adhesiveness, gumminess가 큰 수치를 나타낸다.순구조의 Tonpilz형 초음파 변환기와 비교하여 비록 송파전압감도에 있어서는 약 5 dB 정도의 음향출력의 손실이 불가피하지만, 그 대신 주파수 대역폭을 약 5 재 정도 확대시킬 수 있는 장점이 있기 때문에 이 넓은 주파수 대역을 효과적으로 활용하면 어종식별을 위한 음향산란신호를 정량적으로 수집 및 평가하는 것이 가능하다고 판단된다.n A was 11 ug.이, 0.9 ug/g and 3.7 ug/g in the blood, liver and kidney, respectively.sional-managerial who secure the higher autonomy and stability in their work have the highest life chance in the labor and health, and leisure life

• Korean Journal of Construction Engineering and Management
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• v.22 no.2
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• pp.31-41
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• 2021

The purpose of this study is to analyze the properties of previous studies related to vocations in the construction field. The results of the analysis are as follows. First, The paper has not been published at the beginning of the establishment of the academic foundation for vocational studies, but there was a marked increase over the next 15 years. Second, research related to vocations in the construction field has been more active in engineering than in social science. Third, the primary data method was used much more than the secondary data method, and the quantitative research method through a questionnaire was the most common research method. Fourth, human objects showed the highest frequency as 78.9%, and among them, technicians was the most. Fifth, as the research topic, psychological and behavioral aspects such as job satisfaction, job stress, turnover intention, and organizational commitment were dealt with most, and structural and environmental aspects such as national job competency standards, job analysis, construction accidents, and career development. It was also found that the topic of the research was actively being dealt with.

• Korean Journal of Construction Engineering and Management
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• v.22 no.2
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• pp.106-118
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• 2021

Global governments and initiatives have attempted and integrated various organizational efforts to implement the 17 Sustainable Development Goals (SDGs), presenting a new paradigm of sustainable development to address global issues (climate change, poverty eradication, and human rights). Recently, investment in sustainable finance has expanded to finance the attainment of goals set out in the Paris Agreement and SDGs. Non-financial factors such as environment, social responsibility, and governance (ESG) have become intangible assets that determine the future competitiveness and profitability of companies. Domestic and foreign institutional investors and asset management companies have been expanding their investments based on the ESG performance of companies. In this study, we aim to derive international standards and initiatives that require disclosure of information on corporate social responsibility activities and ESG performance and analyze construction companies' ESG activities and performance levels. The results of this study can be used as the basis to develop platforms for the construction industry ESG ecosystem and the measurement and management of intangible assets. These could ultimately contribute to overcoming the crisis in the future due to the outbreak of the COVID-19 pandemic, fostering net-zero emissions, and preventing fatal workplace accidents in the construction industry.

• Microbiology and Biotechnology Letters
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• v.50 no.1
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• pp.135-146
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• 2022

Obesity is closely associated with profound dyslipidemia, insulin resistance, and fatty liver disease. Recent reports have suggested that alterations in gut microbiota can be linked to diet-induced obesity. In this study, the anti-obesity effects of Weissella confusa WIKIM51 isolated from kimchi were investigated, as evidenced by: i) reduced lipid accumulation and downregulated adipogenesis-related genes in 3T3-L1 adipocytes; ii) suppressed gains in body weight and epididymal fat mass; iii) reduced serum lipid levels, for example, triglyceride and total cholesterol; iv) increased serum adiponectin levels and reduced serum leptin levels; v) downregulated lipogenesis and upregulated β-oxidation-related genes in the epididymal fat; and vi) altered microbial communities. The collective evidence indicate the potential value of W. confusa WIKIM51 as a functional food supplement for the prevention and amelioration of obesity.

• The Journal of Engineering Geology
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• v.33 no.1
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• pp.69-83
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• 2023

Forest fires increase the risk of subsequent soil erosion and mass movement in burned areas, even under rainfall conditions below landslide alert thresholds, by destroying plants and vegetation and causing changes to soil properties. These effects of forest fires can alter runoff in burned areas by altering soil composition, component minerals, soil water repellency, soil mass stability, and soil fabric. Heat from forest fires not only burns shallow organic matter and plants but also spreads below the surface, affecting soil constituents including minerals. This study analyzed X-ray diffraction and physical properties of topsoil and subsoil obtained from both burned and non-burned areas to identify the composition and distribution of clay minerals in the soil. Small amounts of mullite, analcite, and hematite were identified in burned soils. Vermiculite and mixed-layer illite/vermiculite (I/V) were found in topsoil samples from burned areas but not in those from non-burned areas. These findings show changes in soil mineral composition caused by forest fires. Expansive clay minerals increase the volume of soil during rainfall, degrading the structural stability of slopes. Clay minerals generated in soil in burned areas are therefore likely to affect the long-term stability of slopes in mountainous areas.

• The Journal of the Acoustical Society of Korea
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• v.42 no.5
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• pp.403-411
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• 2023

Functional ultrasound imaging, such as elasticity imaging and micro-blood flow Doppler imaging, enhances diagnostic capability by providing useful mechanical and functional information about tissues. However, the implementation of functional ultrasound imaging poses limitations such as the storage of vast amounts of data in Radio Frequency (RF) data acquisition and processing. In this paper, we propose a sub-Nyquist approach that reduces the amount of acquired axial samples for efficient shear-wave elasticity imaging. The proposed method acquires data at a sampling rate one-third lower than the conventional Nyquist sampling rate and tracks shear-wave signals through RF signals reconstructed using band-pass filtering-based interpolation. In this approach, the RF signal is assumed to have a fractional bandwidth of 67 %. To validate the approach, we reconstruct the shear-wave velocity images using shear-wave tracking data obtained by conventional and proposed approaches, and compare the group velocity, contrast-to-noise ratio, and structural similarity index measurement. We qualitatively and quantitatively demonstrate the potential of sub-Nyquist sampling-based shear-wave elasticity imaging, indicating that our approach could be practically useful in three-dimensional shear-wave elasticity imaging, where a massive amount of ultrasound data is required.