• Title/Summary/Keyword: 조직형태

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Proximal-type Epithelioid Sarcoma Involving Perineum - Case Report - (회음부를 침범한 근위형 유상피육종 - 증례보고 -)

  • Park, Yong-Koo;Park, Ho-Chul
    • The Journal of the Korean bone and joint tumor society
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    • v.7 no.2
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    • pp.64-67
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    • 2001
  • Epithelioid sarcoma has been well characterized as a distincitve entity. In the classic form, it occurs in the distal extremities of young adults. However, in the proximal form, it was found mostly in the pelvis, perineum, and genital tract of young to middle-aged adults. Morphologically, the tumor cells had promient epithelioid or rhabdoid features with marked cytologic atypia, and grew in a multinodular pattern. Immunohistochemically, cytokeratin, epithelial membrane antigen, and vimentin were positive in the tumor cells. This reports dealt with 32-year-old male lesion on his perineum. The tumor shows typical features of proximal type epithelioid sarcoma. We also discussed pathological differential diagnosis and prognosis on this particular disease.

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Microscopic Study of Decomposition-Inhibition Effect in Grapefruit-seed Extract in Rat Kidney (자몽추출물의 콩팥조직 부패억제 효과에 관한 현미경적 연구)

  • Hwang, Kyu-Sung; Choi, Ki-Ju;Nam, Yong-Seok;Lim, Do-Seon
    • Applied Microscopy
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    • v.39 no.4
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    • pp.325-332
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    • 2009
  • It has been well known that grapefruit seed extract (GSE) have effects on the deodorization and a wide range disinfectant. But anybody do not research about the decomposition-inhibition effect of GSE. The present study was performed to investigate the decomposition-inhibition effect of GSE by measuring the microscope and electroscope observation with passage of time. A total of 30 healthy Sprague-Dawley (SD) rats weighting from 230 gm to 250 gm were used as experimental animals. One group that do not treated by GSE named control group and the other group that treated by 55% GSE named Experimental group. Under ether anesthesia, right kidney was obtained. Put each sample in $37^{\circ}C$ and humidity $80{\pm}5%$ incubator, we obtained each sample after 0 day, 1 day, 2 days, 3 days, 4 days and 5 days. 4 ${\mu}m$ of paraffin sections were obtained, stained H-E stain and observed by use of a microscope. Morphological change in tissue was similar to control 1 day group and experimental 3 days group. Therefore, decomposition-inhibition effect of GSE continued about 2 days and it protected necrosis. According to above results, the author suggest that 55% GSE is an effective decomposition inhibitor until 2 days on $37^{\circ}C$ and humidity $80{\pm}5%$ conditions.

An Empirical Study on Classification, Business Type, Organizational Culture on Performance of Korean IT SMEs·Venture (중소·벤처기업의 업종, 영업형태, 조직문화가 기업성과에 미치는 영향에 관한 연구: 삼원분산분석(3-way ANOVA)을 중심으로)

  • Roh, Doo-Hwan;Hwang, Kyung-Ho
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.14 no.2
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    • pp.221-233
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    • 2019
  • In Korea, small and medium sized domestic enterprises(SMEs) play an pivotal role in the national economy, accounting for 99.9% of all enterprises, 87.9% of total employment, and 48.3% of production. and SMEs was driving a real force of the development of national economy in many respects such as innovation, job creation, industrial diversity, balanced regional development. Despite their crucial role in the national development, most of SMEs suffer from a lack of R&D capabilities and equipments as well as funding capacity. Public R&D institutes can provide SMEs with valuable supplementary technological knowledge and help them build technological capacity. so, In order to effectively support SMEs, government and public R&D institutes must be a priority to know about the factors influencing the performance related to technology transfer and technological collaborations. In particular, SMEs are not only taking up a large portion of the national economy, but also their influence in politics and economy so strong that raising the competitiveness of small and medium-sized companies is a national policy goal that must be achieved in order to achieve sustained economic growth. For this reason, it is necessary to look specifically at the relationship between concepts such as the environment, strategy, and organizational culture surrounding the enterprise to enhance the competitiveness of SMEs. The paper analyzes 665 companies to find out which organizational culture affects their performance by classification and type of business of SMEs. This study demonstrated that when SMEs seek consistency in their external environment, strategies, and organizational structure to maintain their continued competitiveness. According to three-way analysis of variance (3-way ANOVA) indicates that classification of industries in SMEs has statistically significant main effects, but the type of business and organizational culture do not have significant effects. However, the company's organizational performance (operating profit) of SMES were found to differ significantly in comparison between groups according to classification standards of industries, and therefore adopted some parts. In addition, an analysis of the effect of interaction between the three independent variables of small and medium-sized enterprises has shown that there are statistically significant interaction effects among classification, types of business, and organizational cultures. The results shows that there is an organizational culture suitable for each industry classification and type of business of an entity, and is expected to be used as a basis for establishing promotion policies related to the incubation and commerciality of small and medium-sized venture companies in the future.

Immunohistochemical Staining of Insulin-like Growth Factor-1 in Human Lung Cancer Cells (폐암의 조직학적 형태에 따른 인슐린양 성장인자-1의 면역조직학적 염색의 비교)

  • Park, Ji-Hyun;Kang, Myoung-Jae;Lee, Heung-Bum;Lee, Yong-Chul;Rhee, Yang-Kuen
    • Tuberculosis and Respiratory Diseases
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    • v.48 no.3
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    • pp.324-330
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    • 2000
  • Objective : Lung cancer arises after a series of morphological changes, which take several years to progress from normal epithelium to invasive cancer. Multiple molecular changes and growth factor production have been documented in lung cancers, both small cell and non-small cell types. Insulin-like growth factors(IGFs) are important mitogenic and anabolic peptides, both in vivo and in vitro, and are thought to be significant autocrine-paracrine factors involved in normal and malignant cell proliferation. In this study, the degree of expression of IGF-1 on the immunohistochemical staining in human non-small cell lung cancer(NSCLC) cells and small cell lung cancer (SCLC) cells were investigated. Methods : Immunohistochemical staining for IGF-1 was performed in 15 cases of small cell carcinoma, 15 cases of squamous cell carcinoma, 15 cases of adenocarcinoma, and 12 cases of bronchoalveolar carcinoma. Results : The expression of IGF-1 on the immunohistochemical staining significantly increased in NSCLC cells than in SCLC cells. Conclusion : These results suggest the expression of IGF-1 in human lung cancer cells. The immunohistochemical staining of IGF-1 in lung cancer cell lines may assist in the differentiation of NSCLC and SCLC.

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Age-dependent Changes in Density and Distribution of Mouse Uterine Mast Cells (생쥐 자궁조직 내 비만세포의 연령별 밀도 및 분포 변화)

  • Choi, Young-Ja;Jekal, Seung-Joo;Lee, Chul-Sang;Kim, Jaeman
    • Development and Reproduction
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    • v.12 no.3
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    • pp.243-250
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    • 2008
  • Mast cells containing a variety of mediators in their cytoplasmic granules are widely distributed in connective tissues and mucosal surfaces of skin, airways, and guts. Within these tissues, mast cells are involved in the pathophysiological conditions such as inflammation, self-defense, tissue-remodeling, and autoimmunity. In order to understand the functional roles of master cells in the uterus, we histologically examined the distribution and density of uterine mast cells in the different aged mice. Until 6 weeks mast cells were sparsely detected in the uterus. But at 7 weeks after birth, when estrous cycle begins, the number of mast cells within uterine tissues increased dramatically and the increment of mast cell density continued up to 32 weeks-age. After then, uterine glandular tissue degenerated gradually and density of uterine mast cell decreased. Uterine mast cells were mainly found in the myometrium and they were closely associated with smooth muscle cells, fibroblasts, and collagens, which contents were changed according to the uterine development in the myometrium. These results suggest that uterine mast cells could be involved in myometrial contractions mediated by smooth muscle cells and tissue reconstitution or remodeling during estrous cycle and parturition including the various immunological functions.

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2D Microwave Image Reconstruction of Breast Cancer Detection for Breast Types (유방 조직형태에 따른 유방암 진단 2차원 마이크로파 영상복원)

  • Kim, Ki-Chai;Kim, Tae-Hong;Lee, Jong-Moon;Jeon, Soon-Ik;Pack, Jeong-Ki
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.27 no.7
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    • pp.646-652
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    • 2016
  • This paper presents a tumor detection for breast cancer that utilizes two-dimensional(2D) image reconstruction with microwave tomographic imaging. The breast cancer detection system under development consists of 16 transmit/receive antennas, and the microwave tomography system operates at 1,700 MHz. The four types of breast(ED-, HD-, SC-, and FT-type) are used for image reconstruction. To solve a 2D inverse scattering problem, the method of moments(MoM) is employed for forward problem solving, and the simplex method employed as an optimization algorithm. The results of the reconstructed image show that the ED- and HD-types of breasts are well reconstructed, but SC- and FT-type breasts are not well because of the error including.

Comparison of Foliar Ultrastructure of 3 Dubautia species (Dubautia속(屬) 3종(種) 식물(植物)의 엽육조직(葉肉組織) 미세구조(微細構造) 비교연구(比較硏究))

  • Kim, In-Sun
    • Applied Microscopy
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    • v.24 no.4
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    • pp.13-31
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    • 1994
  • The fine structure of palisade chloroplasts has been studied in the mature leaves of 3 Dubautia species (D. scabra var. leiophylla, D. knudsenii and D. scabra var. leiophylla${\times}$D. knudsenii) to explore variation at the ultrastructural level, since the parental species exhibit quite different morphological and anatomical features. Types of thylakoidal membrane systems, occurrence and distribution of phytoferritin-like structures, lipid droplets, starch grains, mitochondria and microbodies were examined. Four different types of thylakoidal membranes were found in D. scabra var. leiophylla, 2 rather uniform types in D. knudsenii and 3 intermediate types in their hybrid. D. scabra var. leiophylla and the hybrid were marked by statistically significant differences in mean numbers of thylakoids per granum, while no significant difference was found between D. knudsenii and the hybrid. Phytoferritin-like structures which were about $100-120{\AA}$ in diameter as a whole particle each were found in all 3 species. The amount and distribution of particles varied by species. Lipid droplets, plastoglobuli, and starch grains occurred in all 3 species, but the frequency of starch grains also varied with the species. More frequent and larger starch grains were observed in D. knudsenii than in the other two species. Microbodies, or peroxisome, were observed throughout all species. They occurred, either with or without crystalline inclusions, around the chloroplasts.

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Web 기반 정보시스템의 가치시스템 형성을 위한 전략적 활용

  • 이종민
    • Journal of Korea Society of Industrial Information Systems
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    • v.2 no.2
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    • pp.131-142
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    • 1997
  • 급속하게 변화하는 현대적 경영 환경속에서 Web 기반 정보기술은 시장에 용이한 접근을 제공하고, 상품의 차별화를 창출하며, 비용 효율성을 제고하고, 또한 너무 비용이 많이 들어 엄두를 내지 못할 정도의 전환 비용 때문에 동업자나 고객들 간의 의존성을 증가 시킴으로써 기업의 경쟁우위를 성취하는데 적극 활용되고 있음을 보여주고 있다. 그러나 기존 정보시스템의 전략적 활용에 관한 연구는 기업 내부 프로세스의 통합을 통한 경영력 제고에 치중되는 경향을 보여왔으며 협력사간의 조직간 정보교류를 위한 정보인프라의 구축과 같은 조직간 정보시스템의 전략적 활용에 관한 연구는 아직 미흡한 실정이다. 따라서 본 연구는(1)포터91985)의 가치체인과 가치시스템 개념을 정보기술의 가치활동에서의 연계강도와 형태에 따라 분류하여 분석모형을 설정하고, (2) 경영전략의 운용과 혁신사이에서 다리를 놓아주는 학습도구로써 정보시스템 역할을 조직내 /외적인 정보 공유의 형태와 프로세스의 통합유형에 따라 정보시스템을 분류함으로써 (3) 각 부류에 속한 Web 기반 정보시스템의 전략적 의미를 사례연구를 통하여 재조명하는데 그 목적을 두었다.

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Karyological Study of Japanese Quail (Coturnix coturnix japonica) (일본산 메추리(Coturnix coturnix japonica)의 핵형연구)

  • ;;N. S. Fechheimerlr
    • Korean Journal of Poultry Science
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    • v.17 no.4
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    • pp.269-274
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    • 1990
  • Chromosome complements of Japanese quail (Coturnix coturnix japonica) were studied using several tissues which involving testis, leukocytes and embryos. The diploid count was estimated to be 2n=78. Analyzing the metaphase of secondary meiosis in spermatocytes, the haploid count estimated to be n=39. Morphometric analysis were studied by the centromeric index and relative length of 8 macro-chromosomes and Z, W chromosomes The differences of morphological feature were not significant among tissues. Exceptionally the chromosome 4 shelved a considerable variety in the presence of it's short arm.

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The histological structure and the pathological lesions of gill in teleosts (어류의 아기미의 조직학적 구조와 병변)

  • Huh, Min-Do;Jeong, Hyun-Do
    • Journal of fish pathology
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    • v.6 no.1
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    • pp.65-70
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    • 1993
  • The delicate histological structure of gill in teleosts can be easily affected by a variety of biological, chemical or physical detrimental agents because it is directly exposed to the surrounding water. The epithelium of secondary lamella is thin to allow efficient gaseous exchange and this also renders it particularly vulnerable to various pathogens. As well as the main respiratory role, the gill has other various important functions such as acid-base balance, osmoregulation or the excretion of nitrogenous waste products. Thus destruction of epithelial integrity such as epithelial necrosis or thickening can render a fish very vulnerable to respiratory, secretory and excretory difficulties. This article was tried to describe in detail the common processes of pathological responses correlated to the normal histological structures of the gill in teleosts.

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