• The Journal of Korean Orthopaedic Ultrasound Society
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• v.4 no.2
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• pp.59-65
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• 2011

Purpose: To determine the clinical efficacy of the ultrasonography (US) for the diagnosis of the soft tissue masses comparing to the clinical diagnosis through the physical examination. Materials and Methods: 83 consecutive patients with palpable soft tissue masses were presented retrospectively. On the basis of the pathological diagnosis after the operation, the diagnostic accuracies were evaluated the cases diagnosed by history taking and physical examination, and the cases diagnosed by US before the operation. Results: The diagnostic accuracy of the cases using US was higher(86.7%) than that of the cases using physical examination and history taking. The accuracy of US of the epidermal inclusion cyst was 71.4%, ganglion cyst 85.7%, lipoma 88.6%, respectively. Accurate diagnosis were made 54 cases with 65.1% sensitivity in the cases diagnosed by history taking and physical examination. In this case, its accuracy of the ganglion cyst was 56.0%, and the lipoma was 67.9%. Conclusion: US is a useful diagnostic tool for the diagnosis of the palpable soft tissue masses before the operation.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.2
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• pp.351-356
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• 2014

Although the demand for histopathological examinations has been increasing, medical accidents in management of specimens also have been increasing because most of the examinations are processed manually which can cause careless handing, confusing information and mismatching during the procedure. In the future, histopatological examination will be used frequently for handing incurable diseases and verification of new drug. Thus, efficient and error-free management system for handling personalized medical history and test results is infallibly necessary. In this paper, I have proposed an integrated printing system for informatization of histopathological examination that support the u-Healthcare environment based on RFID in near future. The proposed system supports systematization of whole examination process and information of pathological samples. This system will contribute to reduction of costs, improvement of operational efficiency, and mostly fundamental prevention of medical accidents.

• Journal of Veterinary Clinics
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• v.30 no.4
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• pp.296-300
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• 2013

A 7-year-old castrated male Yorkshire Terrier was presented with a palpable intra-abdominal mass. In radiography, a large radioopaque renal mass and small abdominal mass were found on dorsal area of the abdomen. Grossly, red to brown color mass and a cystic structure (hydronephrosis) were embedded in the right kidney. Histopathologically, the mass had many irregular shaped neovascular channels lined by polygonal or oval shaped endothelial cells. These vessels and neoplastic cells had great invasive tendency to adjacent connective or fat tissues. Small abdominal mass had identical morphologic features as in renal mass. According to immunohistochemistry, the neoplastic cells in renal mass demonstrated strong positive signals for vimentin and CD31, and weak positive for von Willbrand factor. However, there were no positive reactions for cytokeratin. Based on the gross, histopathology and immunohistochemistry, this mass was diagnosed as primary renal hemangiosarcoma in a Yorkshire Terrier dog.

• Journal of the Korean Society of Radiology
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• v.12 no.2
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• pp.217-223
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• 2018

This study to search the diagnostic performance of shear wave elastography(SWE) in breast mass and to compare the biopsy result and stiffness obtained from shear wave elastography. Diagnostic breast ultrasonography and SWE were targeted for 157 patients who had breast ultrasonography was diagnosed mass from June 2017 to September 2017. Pathology results of 157 patients showed a benign 92 patients(Age, $44.54{\pm}11.84$) and a malignancy 65 patients(Age, $51.55{\pm}10.54$). Final evaluation, biopsy result, and quantitative SWE result were obtained and compared with each other according to Breast Imaging Reporting and Data System(BI-RADS) of diagnostic breast ultrasonography. Quantitative SWE value and pathologic result showed the highest diagnostic specificity of 83.70% in Emean and sensitivity of 89.23% in Emin. Quantitative SWE result and biopsy result is statistically significant.(p=0.000). The optimal cut-off value for malignant lesions was 66.3 kPa and 63.7 kPa, respectively, for the sensitivity, specificity, high maximum mean elasticity value(Emax) and mean elasticity value(Emean) and this showed the highest diagnostic area under the ROC curve(Az) value compared to other SWE measurement(p=0.000). The addition of SWE to conventional US in breast mass make a increase diagnostic specificity and reduce unnecessary biopsy. Therefore, it is expected that it will be helpful to analyze the breast mass using the above analysis and apparatus.

• Journal of the korean veterinary medical association
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• v.39 no.9
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• pp.835-850
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• 2003

• Proceedings of the KOR-BRONCHOESO Conference
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• 1993.05a
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• pp.104-104
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• 1993

Fine needle aspiration cytology(FNAC) is a valuable method in preoperative diagnosis of thyroid nodule. Authors evaluated one hundred and ten thyroid nodules by FNAC compared with the postoperative histopathologic diagnosis during the period from Jan. 1, 1989 through Dec. 31, 1992. The results were as followed. The sensitivity was 86.5%, specificity 90.4%, false-negative rate 13.5%, false-positive rate 9.6%, positive predictability 91.5%, negative predictability 60.1% and overall diagnostic accuracy 87.3 %.

• Korean Journal of Veterinary Research
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• v.38 no.3
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• pp.664-673
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• 1998

초음파학적 검사에 따라 미만성 저에코 영역, 낭포, 다병소성 낭포 및 비후된 피막 등 비정상적 소견을 보이는 전립선에서 추출한 전립선액과 생검조직에서의 LDH 분획비(LDH I/V)의 평균치는 각각 $0.92{\pm}0.55$, $2.69{\pm}0.82$, 정상군(각각 $0.23{\pm}0.20$, $0.57{\pm}0.36$)에 비하여 유의성(p<0.01) 있게 높았다. 세포병리학적 검사에서 전립선 비대증 및 전립선염으로 나타난 비정상군($2.76{\pm}0.77$의 생검조직 LDH 평균분획비는 정상군($1.38{\pm}1.19$)에 비해 유의성 있게 높았으나 전립선액에서는 분획비의 유의차가 인정되지 않았다. 배양결과에 따른 전립선액 및 조직시료의 LDH 분획비는 정상군과 비정상군 사이에서의 유의성은 인정되지 않았다. 결론적으로 저에코 영역 및 낭포부위는 생검조직과 전립선액의 배양 및 세포병리학적 검사에 따른 비정상성 및 높은 LDH 분획비와 밀접한 연관성을 보였다. 특히 경직장 초음파상에 나타나는 미만성 저에코 영역은 전립선 비대증 및 만성 전립선염 등과 같은 병적 관련성을 내포하고 있는 것으로 사료된다.

• Korean Journal of Clinical Laboratory Science
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• v.47 no.4
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• pp.243-250
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• 2015

A bone marrow biopsy that has undergone decalcification with 10% nitric acid could not be used for various pathological tests and had extremely limited reproducibility. The fixing solution of each experimental group was differentiated in usage, one solution including acid and the other not. The use of the decalcification solution was separated into either acidic or alkaline (EDTA), and further experiments were conducted with differing time phases. When using a fixing solution and decalcification solution which included acid, the specimens were faulty to the extent that all pathological tests were impossible. However specimens that were processed with an EDTA type decalcification solution did not display a non-specific reaction in EBV ISH and were even able to produce results that were at a level suited to various studies or a pathological diagnosis in the FISH, DNA, RNA tests. By improving the fixing and decalcification of bone marrow biopsy, the study was able to make possible ISH, FISH, DNA tests as well as RNA study, and secured the sensitivity, specificity, and reproducibility of various test methods. The stabilization of various test methods that use bone marrow biopsy contributes to the diagnosis, prognosis, prediction, treatment of the patient and provide guidelines for decision-making.

• Tuberculosis and Respiratory Diseases
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• v.48 no.5
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• pp.720-729
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• 2000

Background : Histological analysis of tuberculosis shows a spectrum of findings, from well formed granulomatous inflammation with few bacilli in patient with normal immune response to M. tuberculosis to poorly formed granulomatous inflammation with many bacilli in patient with defective immune response. To evaluate the degree of immune response to M. tuberculosis, we studied the histologic features, including the presence of acid fast bacilli(AFB) in lymph node of patients with cervical tuberculous lymphadenitis, and compared them with clinical characteristics. Methods : We reviewed the histologic features of 33 cases of cervical tuberculous lymphadenitis and processed the excised nodes for auramine-rhodamine staining to detect AFB. The AFB positivity in tissue was compared with the histologic features(degree of granuloma formation, presence of caseation necrosis, presence of neutrophilic infiltration) and clinical characteristics(lymph node size, duration of symptom, presence of local symptom or radiologic evidence of pulmonary tuberculosis). Results : 1) The mean age at diagnosis was 42.4 years, and male to female ratio was 1:4.5. 2) Histologically, all cases showed well formed granuloma and variable degrees of caseation necrosis, and 39% of the cases showed neutrophilic infiltration in the granulomatous inflammation. 3) AFB were confirmed in 52% of the cases, and they were found extracellularly and at the periphery of caseation necrosis. 4) There was no association between AFB positivity and histological features or clinical characteristics. Conclusion : Cervical tuberculous lymphadenitis showed well formed granulomatous inflammation with caseation necrosis, and there was no association between AFB positivity in the tissue and histological or clinical characteristics.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.9
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• pp.4320-4325
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• 2013

This study was investigated the correlation between thyroid fine needle aspiration biopsy and serological test's concentrations. I examined fifty patients who were diagnosed with thyroid cancer from June 2012 to December 2012 in Pathology of a certain university hospital. Healthy fifty people were selected as a control group. Thyroid function tests were used as variables. In conclusion, The thyroglobulin and autoantibody was showed positive correlations in cancer groups. also Thyroglobulin Ab was showed a little correlation. If we examine this study items, we will get help in early diagnosis.