• Proceedings of the KOR-BRONCHOESO Conference
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• 1972.03a
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• pp.16.2-16
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• 1972

Persistance of developmental remnants during fetal life may be attributed to congenital cysts and fistulas in the neck, which are experienced rather rarely. Recently authors have experienced three cases of progressive increased tumor mass in the lateral side of the neck and four cases of tumor mass in the suprathyroid region. We have performed surgical removal under the diagnosis of branchial cysts and thyroglossal duct cysts, respectively. The biopsy specimens were confirmed by histopathological study.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2001.05a
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• pp.505-506
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• 2001

2000년 4월 1일 경, 경북 구룡포소재 넙치양식장에서 임상적으로 체색흑화 및 복수의 저류를 동반하며 1주일만에 총 10만미 중 약 2%(2,000미)가 급성폐사하는 질병이 발생하였다. 발병 당시의 수온은 13~14$^{\circ}C$, 염분농도는 32~33$\textperthousand$ 측정되었으며, 폐사개체는 복부팽만 및 체색흑화를 공통 증상으로 하였다. 세균검사 및 외부기생충 검사에서는 음성이었다. 본 질병은 저수온기 넙치에서 발병하는데, 작년 4월에 발증예가 실험실로 의뢰된 적이 있으며 올해에는 2월 말 경부터 경북 포항 및 남해 상주에서도 발증ㆍ폐사되기 시작하여 넙치 양식장에 큰 피해를 입히고 있다. (중략)

• The Korean Journal of Cytopathology
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• v.7 no.1
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• pp.12-22
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• 1996

Fine needle aspiration(FNA) has been quite successful in identifying benign and malignant breast lesions, but a "gray zone" exists. A total of 697 FNAs of breast were performed at Korea Cancer Center Hospital for a period of one year. One hundred and eleven of the 697 FNAs were diagnosed as atypical or suspicious for malignancy. Among them, we reviewed 74 FNAs, un which histologic diagnoses were made, and applied cytologic grading system proposed by Masood et al (1990) to evaluate the usefulness of this system in minimizing the size of gray zone. Technical problem was responsible for equivocal diagnoses in 19 FNAs Of the remaining 55 FNAs, 18 were benign and 37 were malignant. Among benign conditions, fibroadenoma(5 cases) and fibrocystic disease with fibroadenomatous feature(3 cases) constituted the largest groups. The majority of malignant conditions were infiltrating ductal carcinoma(29 cases), however, those low grade carcinomas Including tubular carcinoma(3 oases), cribriform carcinoma(2 cases), and mucinous carcinoma(2 cases) occupied a relatively large proportion Cytologic grading system was quite useful in minimizing the size of gray lone. The scores of 27 out of 29 usual infiltrating ductal carcinomas belonged to the group of cytologic malignancy, how-ever, only 2 out of 7 low grade carcinomas got scores of malignancy FNA from fibroadenoma or fibrocystic disease with fibroadenomatous features showed a tendency toward high scores. Experience of the cytopathologist and familiarity with cytologic alteration in breast disease cannot be overemphasized.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1979.05a
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• pp.7.1-7
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• 1979

This paper was attempted to analyze 31 cases of fiberoptic bronchoscopy during the period of 8 months from October 1978 till February 1979 in the Chung-Ang University Hospital. The results were as follows; 1) Among 31 cases. 20 cases were male, 11 cases female. Sex ratio was 2 : 1. 2) In age distribution, 22 cases (70.1%) were in 4th-7th decade, and the other age groups showed relatively even distribution. 3) The chief complaints were hemoptysis (11 cases, 35.5%), coughing (9 cases, 29.0%), chest pain (6 cases, 19.4%), dyspnea (3 cases, 9.7%) and others (2cases, 6.5%). 4) In Gram staining of bronchial secretion, Gram (-) diplococci were in 12 cases (38.7%), Gram (+) cocci 10 cases (32.3%), Gram (+) rods 6 cases (19.4%)and Gram (-) rods 3 cases (9.7%). In culture of bronchial secretion, no growth were in 17 cases (54.8%). Neisseria group 6 cases (19.4%), Proteus and Klebsiella group 1 case (3.2%) and mixed group 3 cases (9.7%). In histopathological study, 11 cases (35.5%) revealed chronic bronchitis, 9 cases (29.0%) bronchogenic carcinoma, 3 cases (9.7%) chronic granulomatous disease and 2 cases (6.5%) no specific findings. In 6 cases biopsy specimens were too small to be examined histopathologically. 5) In diagnosis by bronchoscopic appearance and by laboratory examination of bronchoscopically removed specimens, 9 cases(29.0%) were primary carcinoma of bronchus, 6 cases (19.4%) chronic bronchitis, 4 cases (12.9%) pneumonia in the order of freguency

• Korean Journal of Clinical Laboratory Science
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• v.50 no.1
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• pp.54-62
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• 2018

In the 2000's, due to a change in hospital management strategy, the organizational structure shifted from a hierarchical system to a team system. While the hierarchical system is characterized by being activity centered, job title linked, and vertically managed, the team system is characterized by being competency centered, job title segregated, and horizontally managed. The job titles of medical technologist manager was surveyed three times in 1997, 2007, and 2017. It has been confirmed through staff members working at 24 hospitals in more than 500 beds in the metropolitan area. The results of job titles follow are as follow: "Team Leader; Part Leader" 14/24 (59%), "Chief Technologist; Area Head Technologist" 7/24 (29%), and "Chief" 3/24 (12%). The present authors propose an alternative name based on the team system to refine the three job titles currently used by medical technologists. First, the Chief Technologist is unclear if it refers to the Technologist General Manager or Technologist Manager. The Chief Technologist should be changed to "Team Leader". Second, given that Area Head Technologist or Section Chief are on the same position as Head Nurse, we suggest that Area Head Technologist or Section Chief should be changed to "Part Leader". Third, while the organization regulation is marked merely as Department of Laboratory Medicine according to the hierarchical system, it is marked as Laboratory Medicine Team according to the team system. Medical technologists come to have more belongingness, feeling of solidarity, and intimacy under the team system.

• Journal of Chest Surgery
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• v.35 no.4
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• pp.322-324
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• 2002

Herein we report a rare case of primary esophageal malignant melanoma in a 56-year-old gentleman who presented with a 2-month dysphagea. Esophagoscopy reveals a polypoid tumor and a total thoracic esophagectomy was performed through a right thoracotomy and esophageal replacement with stomach. The tumor was proven to be a primary esophageal malignant melanoma by histological and immunohistochemical studies. The pathologic stage was IIa. He received no postoperative adjuvant therapy. He died of liver metastasis at 8 months postoperatively.

• The Journal of the Korean dental association
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• v.58 no.5
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• pp.293-303
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• 2020

Biopsy is a critical method for disease diagnosis and treatment planning. It can be applied from simple inflammatory lesions to malignant tumors. But many general dental practitioners are unfamiliar with the basic knowledge and skills required for biopsy. Moreover, biopsy indications and contraindications for certain diseases may differ depending on the type of dental practice environment and the specialty of the dentist. Biopsy education can increase the choices a dentist has during disease diagnosis. Here we will discuss details on biopsy needed to the general dentist.

• Journal of Chest Surgery
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• v.37 no.10
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• pp.888-891
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• 2004

Basaloid-squamous cell carcinoma, a biologically high-grade variant of squamous cell carcinoma, is predominantly located at upper aerodigestive tract but it is extremely rare in the esophagus. Recently we experienced a case of basaloid-squamous cell carcinoma of esophagus. A 64 year-old man was referred to our hospital because of mucosal nodularity at 35 cm apart from the incisor in endoscopic examination. Result of Biopsy was squamous cell carcinoma. Left transthoracic esophagectomy was performed. Histologically, the lesion of tumor was basaloid-squamous cell carcinoma and no lymph node metastasis was found.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.38-38
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• 1993

DA-125투여에 따라 심근 조직내 지질과산화산물이 증가하였으나 동일용량의 ADM투여군보다는 적게 증가하였다. 적출십장기능 시험과 심전도 측정시 DA-125 투여와 관련된 특이한 변화는 관찰되지 않았으나 심장조직의 병리학적 검사에서는 심근세포의 약한 과립화 현상이 관찰되었다. 반면 ADM 투여군에서는 현저한 적출심장 기능의 저하, 특징적인 심전도변화 및 심근세포내 공포령성 및 과립화등의 변화가 나타났다. 조혈기독성시험에서는 DA-125와 ADM투여에 따라 백혈구 수의 감소가 가장 컸으며 백혈구 수는 약물투여후 4일째 최저치를 나타냈다가 8일후부터 회복하기 시작하여 약물투여 16일후에는 투여전치로 회복되었다. DA-125와 ADM의 조혈기독성의 pattern은 같으나 독성의 정도는 DA-125가 약한 것으로 나타났다.

• Journal of the Korean Society of Radiology
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• v.82 no.3
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• pp.654-669
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• 2021

Purpose To evaluate the accuracy of MRI in predicting the pathological complete response (pCR) and the residual tumor size of breast cancer after neoadjucant chemotherapy (NAC), and to determine the factors affecting the accuarcy. Materials and Methods Eighty-eight breast cancer patients who underwent surgery after NAC at our center between 2010 and 2017 were included in this study. pCR was defined as the absence of invasive cancer on pathological evaluation. The maximum diameter of the residual tumor on post-NAC MRI was compared with the tumor size of the surgical specimen measured pathologically. Statistical analysis was performed to elucidate the factors affecting pCR and the residual tumor size-discrepancy between the MRI and the pathological measurements. Results The pCR rate was 10%. The diagnostic accuracy of MRI and the area under the curve for predicting pCR were 90.91% and 0.8017, respectively. The residual tumor sizes obtained using MRI and pathological measurements showed a strong correlation (r = 0.9, p < 0.001), especially in patients with a single mass lesion (p = 0.047). The size discrepancy between MRI and the pathological measurements was significantly greater in patients with the luminal type (p = 0.023) and multifocal tumors/non-mass enhancement on pre-NAC MRI (p = 0.047). Conclusion MRI is an accurate tool for evaluating pCR and residual tumor size in breast cancer patients who receive NAC. Tumor subtype and initial MRI features affect the accuracy of MRI.