• The Zoological Society Korea : Newsletter
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• v.18 no.2
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• pp.21-25
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• 2001

대부분의 조직은 여러 가지 세포가 모여서 이루어지기 때문에 그 중의 어떤 특정세포에서 발현하는 물질을 분석하려면 조직을 이루고 있는 각각의 세포를 분리해내야 한다. 이렇게 순수하게 세포를 분리해내는 기술 중의 하나가 Laser Captured Microdissection (LCM)이 다. LCM의 개발로 기존에 사용되던 방법에 비하여 빠르고 간편하면서, 매우 정확하게 원하는 세포를 순수 분리해서 그 세포의 분자생물학적 또는 생화학적인 분석을 할 수 있게 되었다. LCM은 현미경으로 조직절편을 관찰하면서 원하는 세포를 낮은 에너지의 laser를 사용하여 도려내는 방법으로 조직절편 이외에도 도말된 혈액이나 자궁경부 조직, 그리고 배양된 세포를 cytocentrifugation한 후에 원하는 세포를 포획 할 수도 있다. LCM을 이용한 연구는 여러 분야에서 다양하게 진행되고 있으며, 특히 같은 조직 내에 존재하는 정상세포와 전이중인 세포, 그리고 암세포를 구분해 냄으로써 암의 전이기전 및 병인 연구에 매우 큰 공헌을 하고 있다. 이렇게 분리된 세포는 RT-PCR, LOH (loss of heterozygosity), microsatellite instability, differential gene profiling, cDNA microarray, Western blot, 2D PAGE protein analysis 등의 기법을 접목하여 연구하게 된다. 본 논단을 통하여 1996년 개발된 LCM의 원리와 이제까지 LCM을 이용한 연구 성과를 살펴보고자 한다.

• Annual Conference of KIPS
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• 2019.10a
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• pp.470-472
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• 2019

Cyber Threat Intelligence (CTI)는 성장하는 사이버 공격에 대응하는 새로운 보안체계 개념으로써 최근 많은 조직에서 보안성을 향상시키기 위해 도입하고 있다. 조직에서 CTI의 도입은 보안 조직간의 위협 정보와 그에 대응할 수 있는 방어 전략을 공유하여 다양한 선제공격을 방어하기 위해 필수적이다. 이에 따라 CTI 위협 정보를 공유하는 조직이 점차 늘어나고 있으며 정보의 양은 점차 많아지고 있다. 하지만 정보를 공유받는 대부분의 조직이 공격자가 악의적으로 잘못된 위협 정보를 수집한 경우 또 다른 사이버 공격으로 이어질 수 있다. 본 논문에서는 CTI 정보 공유에서 사이버 위협 대응 조치 전략을 조직에 적용하기 전에 가상의 네트워크 아키텍처에서 적용시킨 후 평가 및 검증을 통해 공격을 목적으로 한 악의적인 정보가 적용되지 않도록 사전에 방어한다.

• The Journal of the Korean bone and joint tumor society
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• v.1 no.1
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• pp.77-83
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• 1995

Malignant fibrous histiocytoma was classified as fibrosarcoma, liposarcoma, rhabdomyosarcoma in times past and it was first introduced in 1963 to refer to a group of soft tissue tumors and reported in bone in 1972. It was postulated that the origin of tumor cell was derived from histiocytes that could assume the appearance and function of fibroblasts("facultative fibroblasts") at first. But, recently the immunohistochemical studies suggested origin from a primitive mesenchymal cell. The malignant fibrous histiocytoma were commonly misdiagnosed as other tumors such as myxoid liposarcoma, pleomorphic rhabdomyosarcoma, osteogenic sarcoma, leiomyosarcoma, malignant schwannoma, giant cell tumor, hemangiopericytoma, dermatofibrosarcoma protuberans due to the broad morphologic spectrum. The seventeen cases of the malignant fibrous histiocytomas diagnosed at Hanyang University Hospital since 1979 were reviwed, and the suggestions are as follows : 1. No fundamental histologic differences between the MFHs of soft tissues and bones. 2. The other tumors must be excluded in order to diagnose MFH due to wide histologic variety of MFH. 3. The review of the initial tissue slide was necessary for adequate diagnosis because the recurrent MFHs showed different histologic findings from original tumors.

• Korean Business Review
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• v.19 no.2
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• pp.23-46
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• 2006

In modern economic societies, individuals are governed by organizations and they managed their daily lives in one way or another. through such organizations. All activities of the organizations are carried out by the job performance of individuals. Job is a very important factor for both individuals and organizations. The study is the explore. the effect of job characteristics and organizational characteristics on the job satisfaction in the small- and medium- sized firms in Namdong und Banwool Area. Job characteristics and organizational justice were hypothesized to be positively related to job satisfaction. To examine the influence of job characteristics and organizational justice on job satisfactions, data were collected from 320 employees of the small- and medium- sized manufacturing companies in Namdong und Banwool Area. This research took independent variables as the core job characteristics of the job characteristic theory such as skill variety, job stagnation, job importance, autonomy, feed back, and organizational justice as distributive and procedural justice. As a result, I can make the following suggestions. First, The Results show that job characteristics and organizational justice were significant and important predictors of job satisfaction. Secondarily, to raise the job desire of organizational members, job must be designed in such a way that the members can highly recognize their job characteristics.

• Journal of Digital Convergence
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• v.16 no.3
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• pp.385-394
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• 2018

The purpose of this study was to examine the effects of hospital organizational culture, organizational silence and job complexity on turnover intention in nurses working in general hospitals. The subjects were 152 nurses working at general hospitals. Data were collected from April 19, 2017 to April 30, 2017, and statistical analysis was analyzed by hierarchical multiple regression analysis using the SPSS/WIN 22.0 program. As a result of the research, turnover intention showed a positive correlation with resignation and defensive silence, whereas there was negative correlation between consensual organizational culture, sacrifice, suitability and connection of job inclination. The factors affecting the turnover intention were the present work experience, defensive silence, sacrifice, and the explanatory power of turnover intention was 47%. Therefore, in order to lower the turnover intention, it will be necessary to provide various programs to change the communication pattern in the nursing organization, and to provide differentiated welfare system.

• Journal of Digital Convergence
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• v.15 no.11
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• pp.209-220
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• 2017

Organizational environments are becoming increasingly complex, dynamic and interdependent. To overcome these environmental, the Organization pay attention to the Empowering Leadership. And Empowering leadership leads to OCB(Organizational Citizenship Behavior) of the organization's members. To the empirical analysis of the theoretical relationship, we was set up the research model based on the literature research method. We used total 346 questionnaires from the Manufacturing workers in Dea-gu and Kyung-buk region. The results of this study are as followings; First, Empoewering Leadership are positively related to OCBI and OCBO. Second, Self Leadership is positively related to OCBI and OCBO, and Trust is only positively related to OCBI. Third, the mediating effects of Self Leadership is a significant partial mediations effect on the relationship between Empowering Leadership and OCBI, OCBO. This result is contribute to the development of the research field leadership.

• Journal of Yeungnam Medical Science
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• v.10 no.2
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• pp.485-492
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• 1993

Necrotizing lymphadenitis was first recognised as a self-limiting lymphadenitis by Japanese workers in 1972. It is a distinct clinicopathologic entity, but can be mistaken as malignant lymphoma. We have studied clinicopathologic features in 15 cases of necrotizing lymphadenitis. This disease occurs predominantly in young adult. Male-female ratio is 2 : 1. The commonest presentation is lateral cervical lymphadenopathy. Pain, tenderness, and fever can be seen. Biopsy of the lymph nodes from all patients demonstrates the characteristic histologic features : multifocal, relatively circumscribed nodules in the cortex and/or paracortex, consisting of a mixture of activated large lymphoid cells, histiocytes and small lymphocytes. Numerous karyorrhetic debris are present. Neutrophils and plasma cells are strikingly absent.

• Journal of Dental Rehabilitation and Applied Science
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• v.32 no.4
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• pp.330-337
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• 2016

Gingival recession could occur after orthodontic or endodontic treatment. This could influence not only functional and aesthetic problem, but also patient's treatment satisfaction. There are a lot of techniques for preventing gingival recession, but laterally positioned flap with subepithelial connective tissue graft could get definite advantages such as increase of keratinized gingival width and harmonious color match between graft tissue and surrounding tissue. Clinician should select a right patient case and diagnosis with clinical and radiography exam. In a surgical procedure, getting enough amounts of subepithelial connective tissue and flap coverage should be taken into consideration. The clinical outcomes in this case report shows laterally positioned flap with subepithelial connective tissue graft could be a treatment with predictive outcome.

• Journal of Industrial Convergence
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• v.21 no.12
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• pp.37-43
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• 2023

In today's business landscape, collaboration and interoperability are crucial for organizational success and profitability. However, integrating operations across multiple organizations is challenging due to differing roles and policies in Identity and Access Management (IAM). User-centric identity (UCI) adopts a personalized approach to digital identity management, centering on the end-user for authentication and access control. It provides a decentralized system that ensures secure and customized access for each user. UCI aims to address complex security challenges by aligning access privileges with individual user requirements. This research delves into UCI's ability to streamline resource access amidst conflicting IAM roles and protocols across various organizations. The study presents a UCI-based multi-domain access control (MDAC) framework, which encompasses an ontology, a unified method for articulating access roles and policies across domains, and software services melding with UCI infrastructure. The goal is to enhance organizational resource management and decision-making by offering clear guidelines on access roles and policy management across diverse domains, ultimately boosting companies' return on investment.

• Industry Promotion Research
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• v.5 no.2
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• pp.19-25
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• 2020

This study is a study on how to revitalize social and economic organizations in the Chungnam region. For this, the following major results were presented in literature studies based on prior studies. First, it is necessary to upgrade the social economic organization promotion system and system in Chungnam. Second, there is a need to advance the measures to revitalize various social and economic organizations in cities and counties by building an integrated support system for social and economic organizations. Third, it is necessary to expand the public purchase of products of social economic organizations. Fourth, it is necessary to strengthen the business competency of the social economy organization and promote education. Fifth, it is necessary to upgrade the network for social economic organizations and create differentiated businesses. On the other hand, the social economic organization in Chungnam region shown through this study is as follows. First, social and economic organizations should share their willingness to implement policies in the provincial and provincial areas of Chungnam Province and cities and counties in terms of solving and improving various problems in the region. Based on this, it is required to upgrade the social and economic organization area. Second, the Chungnam region needs a shift in awareness that it is a social and economic organization that is a key factor in overcoming changes in the demographic structure due to industrial weakness and aging. Third, a positive shift in awareness is required by shifting awareness and strengthening education on social and economic organizations. To this end, it is necessary to raise the awareness level of local residents through public education and joint public-private education.