• Korean Journal of Clinical Pharmacy
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• v.27 no.2
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• pp.77-82
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• 2017

Background: Clostridium difficile associated diarrhea (CDAD) is a leading cause of hospital-associated gastrointestinal illness. Risk factors for CDAD include advanced age, long-term admission, antibiotics, proton-pump inhibitor or $H_2$ blocker use and immunosuppression. The practice guideline of American Journal of Gastroenterology (2013) suggests metronidazole for the first-line therapy of mild-moderate CDAD as well as vancomycin for severe CDAD. MICU inpatients receiving stress ulcer prophylaxis and antibiotics are susceptible to nosocomial CDAD. Therefore, this study aimed to evaluate occurrence and treatment of CDAD in MICU. Methods: Patients who were admitted to the MICU and had CDAD from August 2012 to August 2015 were analyzed retrospectively. Results: Of the 90 patients with CDAD, 20 patients (2.22%) had mild-moderate CDAD (16 received metronidazole and 4 received vancomycin therapy) and 70 patients (77.8%) had severe CDAD(54 received metronidazole and 16 received vancomycin therapy). Among the patients with mild- moderate CDAD, treatment with metronidazole or vancomycin resulted in same clinical cure in 50% of the patients (p=1.00). Among the patients with severe CDAD, treatment with metronidazole or vancomycin resulted in clinical cure in 40.7% and 50.0% of the patients, respectively (p=0.511). Clinical symptoms recurred in 7.4% of the severe CDAD patients treated with metronidazole and 6.3% of those treated with vancomycin(p=0.875). Conclusion: Our findings suggest that metronidazole and vancomycin are equally effective for the treatment of mild-moderate CDAD; however, vancomycin demonstrated higher clinical cure rate and lower recurrence rate for severe CDAD, although the difference was not statistically significant. For better clinical outcomes, appropriate medication use by disease severity is needed.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.2
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• pp.299-306
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• 2015

The quality for the domestic pavement is evaluated based on flexural strength at the age of 28 days in accordance with KS regulation. Most specimens of the flexural tensile strength used currently are relatively large ones with a dimension of $150{\times}150{\times}550mm$. Accordingly, it is difficult to treat the specimens, and the utilization of a curing tank is low. In this paper, the study tried to resolve the problem by specimen size specified in the code. For this purpose, a flexural strength test was conducted according to the log scale within the specimen size specified by the KS. And, based on the results of this experiment, a comparative analysis was conducted using the prediction formula of Size Effect Law (SEL) proposed by Bazant to examine the correlation between specimen sizes, so as to use the result as basic data for the reduction of the specimen size in the quality evaluation of concrete pavement.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.33 no.3
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• pp.219-224
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• 2000

Reproductive biology of the naked-headed goby, Faronigobius gymnauchen was investigated by means of histological methods. The ovary was consisted of several ovarian lamellae and the oogonia originated from the inner surface of the ovarian lamella. The testis was seminiferous tubule One in internal structure. Seminiferous tubule was consisted of many testicular cysts which contained numerous germ cells in a same developmental stage. The size of group maturity was 4.5 cm intotal length. Gonadosomatic index(GSI) of the female and male was the highest in June and July, respectively. Reproductive cycle could be classified into the growing ($January{\~}March$), maturation ($April{\~}May$), ripe and spent (June{\~}July$), and recovery and resting ($August{\~}December$). Oocyte development was group-synchronous, and yolk nucleus was observed in the early growing oocyte.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.08a
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• pp.260-260
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• 2011

투명 비정질 산화물반도체는 디스플레이의 구동소자인 박막 트랜지스터에 채널층으로 사용된다. 또한 투명하면서 유연성이 있는 소자를 저비용으로 제작할 수 있는 장점을 가진다. 투명 산화물반도체 재료 중 IGZO는 Si 또는 GaAs와 같은 공유결합성 반도체와는 다른 전자 배치로 전도대가 금속이온의 ns 궤도에서 형성되며, 가전도대가 산소 음이온의 2p 궤도에서 형성된다. 특히 큰 반경의 금속 양이온은 인접한 양이온과 궤도 겹침이 크게 발생하게 되며 캐리어의 효과적인 이동 경로를 제공해줌으로써 다른 비정질 반도체와는 다르게 높은 전하이동도(~10 $cm^2$/Vs)를 가진다. 따라서 저온공정에서 우수한 성능의 TFT소자를 제작할 수 있는 장점이 있다. 본 연구에서는 TFT 채널층으로 사용하기 위한 a-IGZO박막의 산소분압에 따른 특성변화를 분석 하였다. a-IGZO박막은 Pulsed Laser Deposition (PLD)를 이용하여 산소분압(20~200 mTorr) 변화에 따라 Glass기판에 증착하였다. 증착된 a-IGZO 박막의 구조적 특성으로는 X-ray diffraction (XRD), Field emission scanning electron microscopy (FE-SEM), 광학적 특성은 UV-vis spectroscopy 분석을 통해서 알아보았다. TFT 채널층의 조건으로는 낮은 off-current, 높은 on-off ratio를 위해 고저항 ($10^3\;{\Omega}cm$)의 진성반도체 성질과 source/drain금속과의 낮은 접촉저항(ohmic contact) 등의 전기적 성질이 필요하다. 따라서 이러한 전기적 특성확인을 위해 transmission line method (TLM)을 사용하여 접촉저항과 비저항을 측정하였고, 채널층으로 적합한 분압조건을 확인해볼 수 있었다.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.02a
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• pp.105-105
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• 2011

ZnO is a promising material since it could be applied to many fields such as solar cells, laser diodes, thin films transistors and gas sensors. ZnO has a wide and direct band gap for about 3.37 eV at room temperature and a high exciton binding energy of 60 meV. In particular, ZnO features high sensitivity to toxic and combustible gas such as CO, NOX, so on. The development of gas sensors to monitor the toxic and combustible gases is imperative due to the concerns for enviromental pollution and the safety requirements for the industry. In this study, we investigated the effect of substrate temperature and post-annealing on structural and electrical properties of ZnO thin films. ZnO thin films were deposited by pulsed laser deposition (PLD) at various temperatures at from room temperature to $600^{\circ}C$. After that, post-annealing were performed at $600^{\circ}C$. To inspect the structural properties of the deposited ZnO thin films, X-ray diffraction (XRD) was carried out. For gas sensors, the morphology of the films is dominant factor since it is deeply related with the film surface area. Therefore, the atomic force microscopy (AFM) and field emission scanning electron microscopy (FE-SEM) were used to observe the surface of the ZnO thin films. Furthermore, we analyzed the electrical properties by using a Hall measurement system.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2003.11a
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• pp.331-336
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• 2003

The advanced spent fuel conditioning process(ACP) was proposed to reduce considerably the overall volume and radioactivity for effective management of the PWR spent fuel in respects on safety and economy. The ACP is under research and development, and have scheduled to perform hot test for demonstration of the ACP after several years. For hot test, hot cell facility of ${\alpha}{\gamma}$ type possess conservative safety is required essentially. A existing hot cell of ${\beta}{\gamma}$ type will be refurbished to minimize construction expenditures of hot cell facility. In this study, the design requirements are established, and the process detail work flow was analysed for the optimum arrangement to ensure effective process operation in hot cell. And also, the basic and detail design of hot cell facility and process and safety analysis was peformed to secure conservative safety of hot cell facility and process.

• Journal of Aerospace System Engineering
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• v.12 no.2
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• pp.23-29
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• 2018

Contrail is type of clouds which are formed by a condensation of water vapour from the aircraft exhaust when the aircraft is flying the cold atmosphere. Since contrails have considerable effect on greenhouse-effect and military stealth efficiency, researches about contrail avoidance technology has been conducted for decades. However, none of the previous researches concerning contrail avoidance was carried out in Korea. Thus, review of the previous study regarding contrail reduction is absolutely needed. In this paper, researches conducted by several countries are categorically introduced, and practicabilities of their methods are analyzed. This paper also suggests some practical and systematized way to conduct future researches about contrail avoidance.

• Journal of Korean Medicine Rehabilitation
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• v.28 no.4
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• pp.71-79
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• 2018

Objectives The aim of this study is to observe the effectiveness of complex Korean medicine treatment applied to the patients with degenerative meniscal tear and the correlation among clinical effectiveness, body mass index (BMI) and Kellgren-Lawrence grade (KL-grade). Methods The study participants were 38 patients who had been diagnosed with degenerative meniscal tear. Participants were classified by BMI, KL-grade and treated with acupuncture, electroacupuncture and pharmacopuncture. Clinical outcomes were assessed using Numeric Rating Scale (NRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC Index) and EuroQol-5 Dimension Index (EQ-5D Index). Results Both NRS and WOMAC scores were significantly reduced after treatment (p<0.001). The EQ-5D for assessing quality of life showed further improvement (p<0.05). A statistically significant correlation was observed between the BMI and NRS, EQ-5D. KL-grade was correlated with WOMAC. Conclusions These results show that complex Korean medicine treatment to the patient with degenerative meniscal tear may be effective as a conservative therapy. Further research is required to confirm the effectiveness of Korean medicine treatment.

• Journal of Korean Society for Quality Management
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• v.49 no.3
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• pp.421-431
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• 2021

Purpose: For improving outgoing quality, this study presents a novel sampling framework based on predictive analytics. Methods: The proposed framework is composed of three steps. The first step is the variable selection. The knowledge-based and data-driven approaches are employed to select important variables. The second step is the model learning. In this step, we consider the supervised classification methods, the anomaly detection methods, and the rule-based methods. The applying model is the third step. This step includes the all processes to be enabled on real-time prediction. Each prediction model classifies a product as a target sample or random sample. Thereafter intensive quality inspections are executed on the specified target samples. Results: The inspection data of three Samsung products (mobile, TV, refrigerator) are used to check functional defects in the product by utilizing the proposed method. The results demonstrate that using target sampling is more effective and efficient than random sampling. Conclusion: The results of this paper show that the proposed method can efficiently detect products that have the possibilities of user's defect in the lot. Additionally our study can guide practitioners on how to easily detect defective products using stratified sampling

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2022.11a
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• pp.187-190
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• 2022

본 논문은 메타버스 등 인공지능 연계 증강/가상현실 부동 중계 플랫폼에서 부동산 영상 기반 매물 소개 시스템 구축에서 사생활 및 개인정보가 영상에 담기게 될 수 있는 위험이 존재하기에 부동산 영상 내의 개인정보 및 민감 정보를 인공지능 기술을 기반으로 검출하여 삭제해주고 복원해주는 인공지능 기술 연구개발을 목표로 하였다. 한국형 부동산 내 민감 object 를 정의하고, 최신 인공지능 딥러닝 기술 기반 민감 object detection 알고리즘을 연구 개발하며, 영상에서 삭제된 부분은 인공지능 기술을 기반으로 물체가 없는 실제 공간영상으로 복원해주는 영상복원 기술도 연구 개발하였다. 한국형 부동산 환경 (영상 촬영 조도, 디스플레이 스타일, 주변 가구 배치 등)에 맞는 인공지능 모델 구축을 위하여, 자체적으로 한국 영상 database 구축 및 Transfer learning for target domain adaptation 을 진행하였다. 제안된 알고리즘은 일반적인 환경에서 98%의 정확도와 challenge 환경에서 (occlusion 빛 반사, 저조도 등) 81%의 정확도를 보였다. 본 기술은 Proptech 분야에서 주목받고 있는 메타버스 기반 온라인 중계 서비스 기술을 활성화하기 위하여 기획되었으며, 특히 메타버스 부동산 중계 플랫폼의 활성화를 위하여 사생활 보호 측면에서 필요한 중요 기술을 인공지능 기술을 활용하여 연구 개발하였다.