• Journal of the Korean Society of Radiology
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• v.11 no.4
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• pp.177-181
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• 2017

Dose response curves using absorbed dose to the biological effect are usually available in case of conventional X beam. However, absorbed dose is not consider in treatment planning for carbon beam such as heavy ions. Because the biological effects also depend on other quantities such as the local variation, which is often characterized by the linear energy transfer (LET). So LQ model cannot explain the entire response of fractionated carbon beam irradiation. The variation in LET with penetration depth leads to substantial differences in biological effect of carbon beam. And it is therefore essential in treatment planning to calculate not only the absorbed dose but also the LET to estimate the biological outcome of the radiation of interest. LET variation plays an important role in the fractionated irradiations. It is suggested that consideration of LET is necessary in biophysical model.

• Journal of Sensor Science and Technology
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• v.5 no.5
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• pp.11-20
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• 1996

In this paper, the characteristics of therapy radiation diode sensors have been studied by using therapy radiation from the MM22 microtron accelerator. The linearity, reproducibility and error ratio were measured for feasibility as a radiation detector. Energy dependence, sensitivity change after a amount of irradiation and output value according to a number of diodes were also measured for same purpose. We have formed pulse shaping of diode signal with nuclear instruments for portal image reconstruction. The percent depth dose ratio according to field size and depth was compared with that of the detector of a ion chamber. Using thirteen silicon diodes, we can directly read diode outputs on a computer monitor after A/D conversion with 16 channels analog to digital conversion board with 12 bit resolution. The possibility for portal image with diodes has been suggested from output comparison between output value with a human phantom and that without a human phantom.

• Progress in Medical Physics
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• v.19 no.2
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• pp.89-94
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• 2008

TomoTherapy has a merit to treat cancer with Intensity modulated radiation and combines precise 3-D imaging from computerized tomography (CT scanning) with highly targeted radiation beams and rotating beamlets. In this paper, we comparing the dose distribution between TomoTherapy and linear accelerator based intensity modulated radiotherapy (IMRT) for 10 Head & Neck patients using TomoTherapy which is newly installed and operated at National Cancer Center since Sept. 2006. Furthermore, we estimate how the homogeneity and Normal Tissue Complication Probability (NTCP) are changed by motion of target. Inverse planning was carried out using CadPlan planning system (CadPlan R.6.4.7, Varian Medical System Inc. 3100 Hansen Way, Palo Alto, CA 94304-1129, USA). For each patient, an inverse IMRT plan was also made using TomoTherapy Hi-Art System (Hi-Art2_2_4 2.2.4.15, TomoTherapy Incorporated, 1240 Deming Way, Madson, WI 53717-1954, USA) and using the same targets and optimization goals. All TomoTherapy plans compared favorably with the IMRT plans regarding sparing of the organs at risk and keeping an equivalent target dose homogeneity. Our results suggest that TomoTherapy is able to reduce the normal tissue complication probability (NTCP) further, keeping a similar target dose homogeneity.

• Radiation Oncology Journal
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• v.13 no.4
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• pp.303-309
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• 1995

Purpose : The effect of dose escalation of up to 6500 cGy on local control and survial was investigated in locally advanced non-small cell lung cancer. Materials and Methods: Ninety eight patients with biopsy-proven unresec-table non-small cell lung cancer without distant metastases or medically inoperable patients with lower-stage were treated with definitive radio-therapy alone. Group A was treated by thoracic irradiation, 6000 cGy or less in total tumor dose with daily fractions of 180 to 200 cGy; and group B was treated with 6500 cGy of same daily fractions. Results : The actuarial overall survival rate for the entire group was 54% at 1 year, 26.6% at 2 years and 16.4% at 3 years with a median survival time of 13 months. Statistically significant prognostic factors that affect survival rate were stage and N-stage. However, no improvement in local control and survival has been seen with higher dose radiotherapy(group B). Conclusion : Dose escalation of up to 6500 cGy was no effect on local control and survival rate. To increase the survival rate of non-small cell lung cancer hyperfractionated radiotherapy or concurrent chemoradiotherapy should be considered.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.825-830
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• 2007

사면에서 발생되는 강우유출과정에 기여하는 대공극의 영향은 그 중요성에도 불구하고 잘 알려져 있지 않다. 특히 대공극의 공간적분포특상에 대한 현장측정은 이뤄지지 않았다. 본 연구의 실험지역은 경기도 포천시 광릉수목원에 있는 작은 소유역이다. 이 지역의 정밀한 측량을 하여 수치고도모형(DEM)을 얻었다. 이 수치고도모형을 바탕으로 수치지형분석을 통해 흐름선을 파악하여 총 20지점을 선정하였다. 각 지점에서의 대공극을 통한 수직적인 유동들은 장력침투계를 사용하여 지표면아래 깊이 10cm에서 측정하였다. 공간적 토양의 특성분포를 파악하기 위해 각 지점에서의 체적밀도와 점토함량을 조사하였다. 토양수분의 공간적 분포 특성은 TDR(Time Domain Reflectometry)방식인 TRASE를 이용하여 토양수분 값을 얻었다. 이러한 다양한 공간적 특성들은 대공극발달의 공간적 분포특성을 파악하는 중요자료가 된다. 소유역을 크게 기여사면 면적을 기준으로 상부, 중부, 하부로 나누어 대공극의 유효 공극율과 대공극흐름율을 계산하였다. 상부에서의 유효 대공극율의 평균값과 변동계수는 각각 4.3%, 42.1%이고, 대공극흐름율의 평균값과 변동계수는 각각 45.0%, 26.6%이다. 중부에서는 유효 대공극율의 평균값과 변동계수는 6.8%, 37.3%이고, 대공극흐름율의 평균값과 변동계수는 56.2%, 14.4% 이다. 그리고 하부에서의 유효공극율의 평균값과 변동계수는 12.5%, 58.3% 이고 대공극흐름율의 평균값과 변동계수는 64.5%, 24%이다. 이는 유효 대공극율과 대공극흐름율의 비율은 기여사면 면적이 증가할수록 증가하였다. 이는 대공극을 통한 물 이송 능력이 원두부로 갈수록 증가한다는 것을 보여주고 있다.e, taurine, methionine, phenylalanine은 함량(含量)이 적었다. 5. 일건(日乾)중 총유리아미노산의 변화(變化)는 생시료(生試料)의 경우 2,041.2 mg%였으나 1일(日) 건조(乾燥) 후는 1,784.0 mg%로 감소(減少)하다가 그 이후 계속 증가(增加)하여 20일(日) 건조(乾燥) 후는 5,277.0 mg%였다. 6. 일건(日乾)중 leucine, isoleucine, valine은 대체로 증가(增加)하는 경향(傾向)을 나타내었으나 aspartic acid, proline, taurine은 대체로 감소(減少)하는 경향(傾向)을 나타내었다. 436.59mg%로 가장 많았고 군유산(軍有山) 차엽(茶葉)이 146.94mg%로 가장 적었으며 일반차엽(一般茶葉)의 평균치(平均値)는 264.59mg%, 용장(龍欌) 차엽(茶葉)이 223.10mg%, Yabukita 차엽(茶葉)이 256.49mg%였다. 7) 이상(以上)의 결과(結果)를 종합(綜合)할 때 용장(龍欌) 차엽(茶葉)은 일반차엽(一般茶葉)과 형질(形質) 뿐만 아니라, 성분(成分)도 다르므로 품종(品種)이 다른 수종(樹種)으로 추정(推定)되며 와운(臥雲) 차엽(茶葉)은 일반차엽(一般茶葉)과 형질(形質)은 다르나 성분상(成分上)의 비슷한 점으로 보아 동일계통(同一系統)의 변이(變異)된 대엽종(大葉種)으로 추정(推定)된다.5(${\pm}0.77$0.77) % 의 오차로 크게 감소하였다. 결론: 방사선이 통과하는 경로에 불균질조직인 폐가 존재할 경우에도 불균질조직에 대하여 조직의 밀도를 이용하여 보정하는 방법을 사용하여 투과선량으로부터 종양선량을 계산할 수 있음을 알 수 있었다.X>로 평균$43.26{\m

• Proceedings of the Korean Vacuum Society Conference
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• 2000.02a
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• pp.189-189
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• 2000

고분자 재료에 이온을 주입함으로서 경도, 내마모, 내피로성의 기계적인 특성과 내부식성 등의 화학적 특성이 향상되며, 표면 전기전도도와 광학밀도(optical density)가 변한다. 본 연구에서는 MPPO(Modified-Polyphenlene Oxide) 표면에 N2, Ar, Xe 이온을 에너지 50keV, 선량(dose)을 1$\times$1015에서 1$\times$1017ions/cm2로 증가시키면서 조사하였다. 이온 조사량의 증가에 따라 표면 저항이 2$\times$1015에서 6$\times$106($\Omega$/$\square$)으로 감소하여 표면 전기전도도가 향상되었다. Ar 이온은 1016ion/cm2이하의 조사량(dose)에서 N2보다 표면 저항을 더 많이 감소하는데 반해 1016ion/cm2 이상의 조사량에서는 Ar과 N2의 표면 저항이 비슷한 값을 나타냈다. Xe은 Ar과 N2이온에 비하여 전체적으로 표면저항이 많이 감소하여 전도도의 향상은 Xe, Ar, N2 순서로 질량이 큰 이온이 조사 효과가 큰 것으로 나타났다. 소재 표면은 SIMS 분석을 통하여 깊이에 따른 주입이온의 분포를 관찰하였으며, 표면 색상은 황색에서 갈색을 거쳐 암갈색으로 변화함으로서 가시광선에 대한 반사율(reflectance)이 감소하고 광학밀도(optical density)가 증가하여 광학적 특성이 변하였다. 이온 주입 후 에너지 전이에 의한 효과는 optical gap를 감소시켜 광학밀도(optical density)와 표면 전기 전도도를 증가시킨다. 이에 따라 본 논문에서는 이온주입에 의한 광학적, 전기적 특성간의 상관관계를 밝히고자 한다.

• The Journal of Korean Society for Radiation Therapy
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• v.33
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• pp.9-14
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• 2021

This study examined dose change depending on the reposition error of the junction at the time of treatment with multi-isocenter volumetric modulated arc therapy. This study selected a random treatment region in the Arccheck Phantom and established the treatment plan for multi-isocenter volumetric modulated arc therapy. Then, after setting the error of the junction at 0 ~ 4 mm in the X (left), Y (upper), and Z (inner and outer) directions, the area was irradiated using a linear accelerator; the point doses and gamma indexes obtained through the Phantom were subsequently analyzed. It was found that when errors of 2 and 4 mm took place in the X and Y directions, the gamma pass rates (point doses) were 99.3% (2.085) and 98% (2.079 Gy) in the former direction and 98.5% (2.088) and 95.5% (2.093 Gy) in the latter direction, respectively. In addition, when errors of 1, 2, and 4 mm occurred in the inner and outer parts of the Z direction, the gamma pass rates (point doses) were found to be 94.8% (2.131), 82.6% (2.164), and 72.8% (2.22 Gy) in the former part and 93.4% (2.069), 90.6% (2.047), and 79.7% (1.962 Gy) in the latter part, respectively. In the X and Y directions, errors up to 4 mm were tolerable; however, in the Z direction, error values exceeding 1 mm were beyond the tolerance level. This suggests that for high and low dose areas, errors in the direction same as the progress direction in the treatment region have a more sensitive dose distribution. If the guidelines for set-up errors are established at the institutional level through continuous research in the future, it will be possible to provide good quality treatment using junctions.

• The Journal of Korean Society for Radiation Therapy
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• v.22 no.2
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• pp.123-129
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• 2010

Purpose: The purpose of this study was to evaluate dosimetric characteristics of Optically stimulated luminescent dosimeters (OSLD) for dosimetry Materials and Methods: InLight/OSL $NanoDot^{TM}$ dosimeters was used including $Inlight^{TM}MicroStar$ Reader, Solid Water Phantom, and Linear accelerator ($TRYLOGY^{(R)}$) OSLDs were placed at a Dmax in a solid water phantom and were irradiated with 100 cGy of 6 MV X-rays. Most irradiations were carried out using an SSD set up 100 cm, $10{\times}10\;cm^2$ field and 300 MU/min. The time dependence were measured at 10 minute intervals. The dose dependence were measured from 50 cGy to 600 cGy. The energy dependence was measured for nominal photon beam energies of 6, 15 MV and electron beam energies of 4-20 MeV. The dose rate dependence were also measured for dose rates of 100-1,000 MU/min. Finally, the PDD was measured by OSLDs and Ion-chamber. Results: The reproducibility of OSLD according to the Time flow was evaluated within ${\pm}2.5%$. The result of Linearity of OSLD, the dose was increased linearly up to about the 300 cGy and increased supralinearly above the 300 cGy. Energy and dose rate dependence of the response of OSL detectors were evaluated within ${\pm}2%$ and ${\pm}3%$. $PDD_{10}$ and PDD20 which were measured by OSLD was 66.7%, 38.4% and $PDD_{10}$ and $PDD_{20}$ which were measured by Ion-chamber was 66.6%, 38.3% Conclusion: As a result of analyzing characteration of OSLD, OSLD was evaluated within ${\pm}3%$ according to the change of the time, enregy and dose rate. The $PDD_{10}$ and $PDD_{20}$ are measured by OSLD and ion-chamber were evaluated within 0.3%. The OSL response is linear with a dose in the range 50~300 cGy. It was possible to repeat measurement many times and progress of the measurement of reading is easy. So the stability of the system and linear dose response relationship make it a good for dosimetry.

• Progress in Medical Physics
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• v.21 no.1
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• pp.29-34
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• 2010

In this study, we have fabricated a fiber-optic dosimeter for a proton beam therapy dosimetry. We have measured scintillating lights with the various kinds of organic scintillators and selected the BCF-12 as a sensor-tip material due to its highest light output and peak/plateau ratio. To determine the optimum diameter of BCF-12, we have measured scintillating lights according to the energy losses of proton beams in a water phantom. Also, we determined the adequate length of organic scintillator by measuring scintillating lights according to the incident angles of proton beam. Using an optimized fiber-optic dosimeter, we have measured scintillating lights according to the dose rates and monitor units of proton accelerator.

• The Journal of the Korea Contents Association
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• v.8 no.11
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• pp.203-209
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• 2008

Nowadays the risk of radiation is getting more serious, so we must know the exact dose that was irradiated, Because very high radiation dose is used in radiation therapy field. We used the ionization chamber which measure the radiation dose in this study. We tried to know the incorrect result from the distortion of geometric structure of ionization chamber and we studied how to find the distortion of geometric structure of ionization chamber. We used a radio fluoroscopy to find the wound degree of electrode of ionization chamber and a reconstructed 3D CT image to analyze the wound degree of electrode quantitatively. we measured degree of distortion by comparing with absorbed dose of normal electrode and wound electrode. The comparative result is not absolute dosimetry at specific point but relative dosimetry between thats. We measured 4 MV, 10MV photon with same absorbed dose and dose rate. The degree of distortion of wound electrode was totally $5.5{\sim}7.2%$, and there was no difference between two energies. The variation induced from radiation dose to be irradiated and dose rate, and the degree of distortion from wound direction also was almost similar value. We could find that the geometric structure of ionization chamber that can influence a basic measurement of radiation dose can be changed by old usage and inattention of management in this study, especially winding of electrode can be happened, in radiation therapy field, It is very important to keep precise radiation dose quantitatively.