• Title/Summary/Keyword: 제니스

Search Result 114, Processing Time 0.021 seconds

Effect of Dietary Fat and Genistein on Lipid Metabolism and Antioxidant Activity in Hyperlipidemic Male Rats induced High Fat Diet (고지방식이로 유도된 고지혈증 모델 흰쥐에서 지방과 제니스테인 섭취가 지질대사 및 항산화능에 미치는 영향)

  • Kim Mi-Hyun;Jang So-Young;Lee Yeon-Sook
    • Journal of Nutrition and Health
    • /
    • v.39 no.2
    • /
    • pp.100-108
    • /
    • 2006
  • This study was conducted to investigate whether dietary factors, normal fat and genistein leads to beneficial improvement of lipid metabolism and oxidative stress in adult hyperlipidemic male rats. Seven wk-old male SD rats were fed high fat diet (15% fat, 1% cholesterol) for 4 wks for induction of hyperlipidemic model rat. Weight-matched rats were then assigned to four groups according to dietary fat level (7% or 15% fat) and genistein contents (0 or 320 mg/kg diet). Food intake was significantly decreased by both high fat intake and genistein supplementation compared with normal fat intake and genistein no supplementaion. But weight gain was significantly decreased by genistein supplementation in normal fat intake compared with the other groups. Total lipid, total cholesterol and triglyceride in serum and liver were significantly decreased by normal fat intake compared with high fat intake. But total cholesterol in liver was significantly increased by genistein supplementation in both high fat and normal fat intake. TBARS in serum and liver was less produced by normal fat intake compared with high fat intake but TBARS in liver was significantly increased by genistein supplementation compared with genistein no supplementation in normal fat intake. Glutathione reductase activity in erythrocytes was significantly reduced by genistein supplementation in normal fat intake compared with the other groups. Glutathione peroxidase and glutathione reductase activities in liver were significantly inhibited by normal fat intake compared with high fat intake. Catalase activity in liver was significantly increased by genistein supplementation compared with genistein no supplementation in high fat intake. Nitrite was significantly decreased by normal fat intake compared with high fat intake. These results suggest that normal fat intake has the treatment effect against risk factors related with cardiovascular disease by reducing lipid profiles, lipid peroxidation. And genistein shows action as a antioxidant replacing antioxidant enzymes but also may act as prooxidant causing the production of TBARS.

Design and Implementation of Topology Generator for Sm art Factory Security Endpoint Identification (스마트팩토리 보안 앤드포인트 식별을 위한 토폴로지 제네레이터 설계 및 구현)

  • Yanghoon Kim
    • Journal of Platform Technology
    • /
    • v.11 no.3
    • /
    • pp.76-82
    • /
    • 2023
  • Starting from the 4th industrial revolution, core technologies were applied to industries to build various smart environments. Smart factories in the manufacturing industry produce high-quality products by applying IIoT as a core technology that can collect and control a wide range of data for customized production. However, the network environment of the smart factory converted to open through IIoT was exposed to various security risks. In accordance with security breaches, IIoT has shown degradation in the quality of manufactured products and production processes due to network disturbance, use and maintenance of forged IIoT, and can cause reliability problems in business. Accordingly, in this study, a method for safe connection and utilization of IIoT was studied during the initial establishment of a smart factory. Specifically, a study was conducted to check the IIoT connection situation so that the practicality of the IIoT connected to the smart factory could be confirmed and the harmless environment established.

  • PDF

A Study on Current Trends and Classification of Korean Platform Firms (국내 플랫폼 기업 현황 분석과 시사점: 플랫폼 기업 유형 분류를 중심으로)

  • Jin, Hyunseo;Kim, Juhee;Kim, Dohyeon
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.17 no.3
    • /
    • pp.229-243
    • /
    • 2022
  • The importance of digital economy and platform firms in the Korean economy is growing. However, the concept and definition of platform firms are still in vague. In addition, the construct of platform firms in ecosystem has not yet investigated. In this paper, we attempt to define the platform firm and to classify the platform depends on the attributes of firms and business. We find 552 platform firms compose Korean platform ecosystem. From this study, the understood of platform concept can be accurated. Specifically, from the perspective of a 'firm' rather than a business-oriented attribute, and furthermore, the type of platform firm and detailed classification of industries and services were proposed for empirical analysis in the future. In addition, through the analysis of the current status of the platform ecosystem, policy recommendations for the future development and activation of the ecosystem were presented.

Protective Effect of Isoflavone, Genistein from Soybean on Singlet Oxygen Induced Photohemolysis of Human Erythrocytes ($^1O_2$으로 유도된 사람 적혈구의 광용혈에 있어서 대두의 아이소플라본인 제니스테인의 보호작용)

  • Park, Soo-Nam
    • Korean Journal of Food Science and Technology
    • /
    • v.35 no.3
    • /
    • pp.510-518
    • /
    • 2003
  • Protective effects of natural components including genistein (4',5,7-trihydroxyisoflavone) from Glycine max MERRILL on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. Genistein $(10{\sim}100\;{\mu}m)$ suppressed photohemolysis in a concentration-dependent manner, and was more effective than the lipid peroxidation chain blocker, ${\alpha}$-tocopherol (Vit. E). Glycoside of genistein, genistin, the water-soluble antioxidant, L-ascorbate, and the iron chelator, myo-inositol hexaphosphoric acid dodecasodium salt (sodium phytate) did not exhibit protective effect against photohemolysis. L-Ascorbate and sodium phytate stimulated photohemolysis at high concentration $(500\;{\mu}m)$. ${\alpha}$-Carotene 3,3'-diol (lutein), a singlet oxygen $(^1O_2)$ quencher, exhibited pronounced protective effect, an indication that $^1O_2$ is important in photohemolysis sensitized by rose-bengal. Reactive oxygen scavenging activities $(OSC_{50})$ of natural antioxidants including genistein on reactive oxygen species (ROS) generated in $Fe^{3+}-EDTA/H_2O_2$ system using the luminol-dependent chemiluminescence assay were in the order of sodium phytate > L-ascorbate > ${\alpha}$-tocopherol > genistein > genistin. $OSC_{50}$ value of genistein, genistin, ${\alpha}$-tocopherol, L-ascorbate, and sodium phytate were 41.0, 109.0, 9.0, 5.2, and $0.56{\mu}m$ respectively. The order of free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activity $(FSC_{50})$ was L-ascorbate > ${\alpha}$-tocopherol > genistein > genistin. These results indicate that genistein can function as an antioxidant in biological systems, particularly skin exposed to solar UV radiation by scavenging $^1O_2$ and other ROS, and to protect cellular membranes against ROS.

Moisturizing and Anti-oxidation Effect of Astragalus membranaceus Root Extract (황기추출물의 보습 및 항산화 효과)

  • Jung, Taek-Kyu;Kim, Mi-Jin;Lim, Kyung-Ran;Yoon, Kyung-Sup
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.32 no.3 s.58
    • /
    • pp.193-200
    • /
    • 2006
  • We investigated the effect of moisturizing and anti-oxidation of Astragalus membranaceus (Astragali Radix) root extract with respective to growing districts and extract methods for the purpose of development of cosmetic ingredients. Astragalii Radix was collected in Jecheon, Jeongseon, Taebaek, and Yeongju in Korea and China as growing districts. Formononetin was determinated by HPLC method as one of the various active agents in Astragalus membranaceus root extract. The 75% ethanol extract demonstrated to be more effective than $H_2O$-extracted one for a scavenging activities to DPPH radicals and reactive oxygens. The 75% ethanol extract showed $IC_{50}$ (50% scavenging concentration) of 2.162 mg/mL and 2.981 mg/mL in case of free radical scavenging activity test and reactive oxygen scavenging activity test, respectively Especially, free radical scavenging activity of isoflavonoids isolated from ethylacetate fraction was similar to scavenging activity of genistein. Astragalus membranaceus root extract of Jecheon district by sonicating extraction method was more effective in skin hydration compared with others.

Effects of Capillary Water Interruption Layer on the Growth of Zoysiagrasses and Cool-season Turfgrasses in Reclaimed Land (염해지에서 모세관수 차단층 설치 유무에 따른 한국잔디 및 한지형 잔디류의 생육)

  • Kim, Jun-Beom;Yang, Geun-Mo;Choi, Joon-Soo
    • Asian Journal of Turfgrass Science
    • /
    • v.23 no.1
    • /
    • pp.35-44
    • /
    • 2009
  • This study was carried out to examine the growth performance of 4 species of cool-season grasses and 4 species of zoysiagrasses under salt injury in Seo-san reclaimed area. Grasses were grown on the plots with capillary water interruption layer (WCWIL) and without capillary water interruption layer (WOCWIL) soil systems. Cool-season grass and seeding-type zoysiagrass plots were seeded on 6 Jun, 2006. Vegetative zoysiagrass 'Junggi' was established by sprigging and 'Senock' and 'Millock' were plugged. Electric conductivities of irrigation water (ECw) ranged from 0.28 to $3.3\;dS{\cdot}m^{-1}$. Electric conductivities (ECe) of the soil with capillary water interruption layer and without capillary water interruption layer ranged from 0.55 to $9.4\;dS{\cdot}m^{-1}$ and from 1.84 to $9.4\;dS{\cdot}m^{-1}$ respectively. Leaf color, turf quality, coverage rates, and growth rates were rated visually for 2 years. Zoysiagrass 'Junggi', creeping bentgrass, zoysiagrass 'Senock' and 'Millock' showed acceptable growth at salty fairway condition, while Kentucky bluegrass, perennial ryegrass, Kentucky bluegrass mixed with perennial ryegrass, and seeded zoysiagrass 'Zenith' showed establishment rates below 70%. These results will be useful when choosing turf grass species and cultivars for the golf courses in reclaimed land area.

A Study on Survey and Analysis of Landscape Plans for Improving the Quality of Life in Rural Areas -Focus on Byeongyeong-myeon, Gangjin-gun, Jeollanam-do- (농촌지역민 삶의 질 개선을 위한 경관계획 조사·분석에 관한 연구 -전라남도 강진군 마량면을 중심으로-)

  • Jeong, Gun-Young
    • Journal of Digital Convergence
    • /
    • v.18 no.12
    • /
    • pp.133-138
    • /
    • 2020
  • The purpose of this study is to explore the methods to activate and functional changes of rural centers to improve residents' quality of life and secure sustainability in rural areas. The existing policy for activating rural centers lacks for placeness because walking-focused features of a Myeon seat have been changed due to the improvement of physical environment for easy car accessibility. They also wanted to solve abandoned houses and secure parking lots in the landscape plan. Based on analysis results, design guidelines were suggested. Long-stay tourism programs for outside visitors should be developed through the rural center activation project. They should be linked with projects for preserving the history of Byeongyeong Fortress and developing Hamel Village. Mountain trails and waterfront should be created to enhance accessibility and linkage methods with other resources should be prepared. As Byeongyeong-myeon has various tourism resources, design guidelines for each element should be made for a macroscopic direction and systematic landscape management.

Classification of Service Quality for HMR unmanned store business (HMR 무인매장 서비스 품질 분류에 관한 연구)

  • Jong Won Lee
    • Journal of Service Research and Studies
    • /
    • v.13 no.2
    • /
    • pp.41-61
    • /
    • 2023
  • The universal form of life in the era of the 4th industrial revolution can probably be summarized as the keyword "non-face-to-face". In particular, in terms of consumption activities, face-to-face contact is gradually changing to a system that minimizes, and offline stores are rapidly changing to non-contact services through kiosks and robots. The social structure is also changing with the passage of time, and most fundamentally, our dietary consumption patterns are changing. In particular, the increase in single-person households and the aging population are having a great impact on changes in the food service industry, which is closely related to dietary life. The HMR (Home Meal Replacement) market has grown significantly as the labor of cooking at home has decreased and the use of substitute foods has increased. As the size of the market has grown, the types of businesses that provide products have also diversified. The development of technology, non-face-to-face culture, and corporate management efficiency are intertwined, and unmanned stores are spreading recently. In this study, service quality attributes of HMR unmanned stores, where competition is gradually intensifying, are classified, and service quality classification using the Kano model and Timko's customer satisfaction coefficient are calculated to provide implications for service management based on customer satisfaction. As a result of the analysis, 'products with short cooking time' and 'variety of products (menu)' were classified as attractive qualities, and 'cleanliness inside/outside of the store' and 'products at reasonable prices' were classified as unified quality. In addition, 'convenience of self-checkout process' was classified as a natural quality, and 'convenience of in-store passage' was classified as an indifferent quality. Furthermore, when the service factor was satisfied within the HMR unmanned store, the factor with the highest satisfaction coefficient was 'product (menu) variety', and the factor with the highest dissatisfaction factor was 'convenience of self-checkout process'. Through the results of this study, it is intended to derive priorities in service quality management of HMR unmanned stores and provide strategic implications for related businesses.

The Influence of Website Charateristics on Customer Satisfaction, Customer Loyalty, and Repurchase Intention in Internet Shopping Malls (인터넷 쇼핑몰에서 웹사이트 특성에 따른 재구매의도에 대한 연구 -고객만족과 고객충성도를 중심으로-)

  • Shin, Ho-Kyoung;Hong, Jung-Han;Kim, Kyung-Kyu
    • The Journal of Society for e-Business Studies
    • /
    • v.12 no.1
    • /
    • pp.41-71
    • /
    • 2007
  • Researchers have continuously investigated the issues of customer satisfaction, customer loyalty, and repurchase intention of customers in Internet shopping malls, a fast growing e-bisiness model in Korea. At present, most Internet shopping malls in Korea offer similar services to their customers. This has caused intense industry competition, and the Internet shopping malls have made significant investments into their websites in order to remain attractive to their customers. This research examines the relationships among website charateristics, customer satisfaction, loyalty, and repurchase intention. Website characteristics include context, commerce, connection, communication, contents, community, and customization. We have used data from a field study of 662 individuals to test the proposed model. The results of this research show that among the 7 website characteristics, context, communication, content, and commerce are the significant determinants of customer satisfaction. In turn, customer satisfaction increases customer loyalty and repurchase intention. These findings have important theoretical and practical implications, which are discussed in the paper.

  • PDF

Cost Analysis of Modified Asphalts using a Performance Based Fracture Criterion (공용성에 근거한 파괴기준을 이용한 개질 아스팔트 포장의 비용 효과 분석)

  • Kim, Boo-Il
    • International Journal of Highway Engineering
    • /
    • v.7 no.4 s.26
    • /
    • pp.49-56
    • /
    • 2005
  • The effect of modified asphalts is evaluated by simple comparison of a single parameter (i.e., tensile strength, stiffness, etc.) between modified asphalt mixture and unmodified mixture. The use of a single parameter to evaluate the effect of modified asphalt must be questioned. Rather, a single unified framework that accounts for changes in key mixture properties is needed to effectively evaluate the modified asphalt mixtures. This study used a new performance-based fracture parameter as a single unified framework, the Energy Ratio (ER), for quantifying the effect of modified asphalts oil the fracture resistance of mixtures. The Energy Ratio was then used as a performance criterion for calculating the construction cost of two modified asphalt pavements (SBS and Crumb Rubber) and unmodified asphalt pavement. The results showed that the Energy Ratio of SBS modified asphalt was higher than those of crumb rubber and unmodified asphalt. Cost analyses indicated that the construction cost of the AC layer would be reduced by up to 24% by SBS modification. Based on the results, the Energy Ratio is capable of evaluating the effect of modified mixtures, and may form the basis of a promising fracture criterion for performance-based thickness design in asphalt pavements.

  • PDF