• Tuberculosis and Respiratory Diseases
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• v.43 no.5
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• pp.720-727
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• 1996

Objectives: $^{201}TI$ - chloride, $^{99m}Tc$ - MIBI, $^{99m}Tc$(V) - DMSA SPECT has been used in distinguishing lung cancer from benign lesion. To compare the diagnostic efficacy of SPECT with these tumor - seeking agents, we perfonned three consecutive SPECT using $^{201}TI$, $^{99m}Tc$ - MIBI, $^{99m}Tc$(V) - DMSA in same subjects with a solitary pulmonary lesion. Methods: SPECT was carried out at 10min and 3hr for $^{201}TI$ after injection of 20mCi, and 2hr for $^{99m}Tc$ - MIBI and $^{99m}Tc$(V) - DMSA after injection of 20mCi, respectively, in 37 patients with a solitary pulmonary lesion(27 lung cancer and 10 benign diseases). In patients showing visual uptake on lesion site, we obtained the lesion - to - background(target lesion/contralateral normal lung) uptake ratio from transverse slice for each radionuclide and also calculated the retention index for $^{201}TI$. Results: The diagnostic sensitivity of $^{201}TI$, $^{99m}Tc$ - MIBI and $^{99m}Tc$(V) - DMSA SPECT to lung cancer was 100%, 96% and 73%, and the specificity was 40%, 70% and 70%, respectively. The low specificities for these agents were mainly due to high positive uptake in patients with active pulmonary tuberculosis. There were no significant differences in uptake ratios and retention index between malignant and benign lesions, and among the histologic types of lung cancer. Conclusion : $^{201}TI$ and $^{99m}Tc$ - MIBI showed higher sensitivity than $^{99m}Tc$(V) - DMSA for detecting lung cancer, but was of limited usefulness in distinguishing lung cancer from benign lesion due to low specificity, especially in area with a high prevalence of active pulmonary tuberculosis.

• Journal of Intelligence and Information Systems
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• v.27 no.1
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• pp.177-190
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• 2021

Due to the development of the fourth industrial revolution technology, efforts are being made to improve areas that humans cannot handle by utilizing artificial intelligence techniques such as machine learning. Although on-demand production companies also want to reduce corporate risks such as delays in delivery by predicting total production time for orders, they are having difficulty predicting this because the total production time is all different for each order. The Theory of Constraints (TOC) theory was developed to find the least efficient areas to increase order throughput and reduce order total cost, but failed to provide a forecast of total production time. Order production varies from order to order due to various customer needs, so the total production time of individual orders can be measured postmortem, but it is difficult to predict in advance. The total measured production time of existing orders is also different, which has limitations that cannot be used as standard time. As a result, experienced managers rely on persimmons rather than on the use of the system, while inexperienced managers use simple management indicators (e.g., 60 days total production time for raw materials, 90 days total production time for steel plates, etc.). Too fast work instructions based on imperfections or indicators cause congestion, which leads to productivity degradation, and too late leads to increased production costs or failure to meet delivery dates due to emergency processing. Failure to meet the deadline will result in compensation for delayed compensation or adversely affect business and collection sectors. In this study, to address these problems, an entity that operates an order production system seeks to find a machine learning model that estimates the total production time of new orders. It uses orders, production, and process performance for materials used for machine learning. We compared and analyzed OLS, GLM Gamma, Extra Trees, and Random Forest algorithms as the best algorithms for estimating total production time and present the results.

• Korean Journal of Microbiology
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• v.31 no.2
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• pp.166-174
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• 1993

Streptomyces coeUc%r (Muller) cells were treated with $100 \mu$M hydrogen peroxide for I hour and proteins synthesized during hydrogen peroxide stress were labeled with L-[$^{35}S$]-methionine. Total cellular proteins were extracted and analyzed by two-dimensional polyacrylamide gel electrophoresis. In exponential growth phase, synthesis of about 100 proteins was increased by hydrogen peroxide treatment. These proteins were named as Pin (£eroxide-inducib]e) proteins and classified into 4 subgroups according to their induction time after hydrogen peroxide treatment. About 60 of them were found to be induced within 20 minutes and maintained throughout I hour of treatment. In stationary growth phase. synthesis of 62 proteins was increased by hydrogen peroxide and 21 of them were the same Pins found in exponential growth phase. Proteins from the mutants which are resistant to hydrogen peroxide were obtained in exponential growth phase and compared with those from the wild type on two-dimensional gel. The three mutants, N7, N9. and N24, were found to have higher constitutive leve]s of ]5, 17, and 15 Pin proteins respectively, than the wild type. 9 of these Pin proteins (D74.7a, E76.0c, E23.3. F50.7, F47.2a. F25.5, G39.6b, G24.0, H39.6a) increased in two of the three mutants and 3 proteins (F39.7, H6I.7. 120.8) increased in all of the three mutants. These proteins might play important roles in the response of S. coelic%r to hydrogen peroxide.

• Journal of Korean Society on Water Environment
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• v.33 no.2
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• pp.170-180
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• 2017

The study used jet water flow, ultra-sonication and ozonation system units to investigate impact of the unit components on water quality of stagnant Yeo-cheon River reach, Korea. Samples were collected at six locations, before operation and after 1, 3 and 6 hrs of operation. By operating the water flow unit only, dissolved oxygen increased as high as 90% after 3 hr at 25 m downstream of the device and Chl-a was reduced by 80%. Incorporating sonication, greater than 80% of Chl-a was removed even at 100 m distance from the device. Besides, total dissolved phosphorus was reduced from an average value of $420({\pm}70){\mu}g/L$ before ultrasonic irradiation to $160({\pm}40){\mu}g/L$ after the treatment. Releasing ozone into the flow with sonication, Chl-a was considerably removed from the water column and ammonia nitrogen was also decreased to average value of $20{\mu}g/L$ from $60{\mu}g/L$. However, as only $3{\ast}10^{-3}mg/L$ of ozone was used for safety purpose and due to brief reaction time it takes, effect of integrating ozone to the system covered limited area. Generally, combining sonication to jet flow is promising in preventing algal bloom formation since it has effectively removed Chl-a from the water column.

• Korean Journal of Microbiology
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• v.30 no.6
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• pp.533-538
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• 1992

The generation time of Methylobacterium extorquens AMI growing on methanol at pH 5.5 and 7.0 was found to be 23 hand 8.3 h. respectively. The bacterium grown at pH 7.0 were found to contain more amounts of spermidine and putrescine than the cell grown at pH 5.5. Cells grown at both conditions exhibited strong methanol dehydrogenase (MDH) activity at the mid-exponential growth phase. The amounts of MDH. however. were found to be almost equal through all gro~1h phases. Cells growing at the stationary phase contained large amounts of cytochrome c. The cytochrome c content was higher in cells growing at pH 7.0 than the cells growing at pH 5.5. Cells growing at pH 5.5 in the presence of putrescine or spermidine contained increased amounts of putrescine. The level of spermine, however. was decreased and that of spermidine was not changed. Spermine added into the medium was found to have no effect on the level of cellular polyamines. Putrescine or spermidine added into the medium stimulated MDH and hydroxypyruvate reductase activities. but did not affect the contents of MDH and cytochrome c. It was found that preincubation of cell-free extracts with polyamines does not stimulate MDH and hydroxypyruvate reductase activities.

• Journal of Korean Society of Transportation
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• v.25 no.2 s.95
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• pp.73-81
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• 2007

The purpose of this paper is to perform a basic study on the interaction between lanes, which can be achieved through analyzing traffic breakdown at the microscopic level. Using aerial photographic data for the microscopic analysis, this study analyzed the characteristics of traffic flow at a merging area. This research produced aggregated traffic data such as flows, speeds, and densities in 30 second intervals by lane for the macroscopic analysis and individual headway data by lane for the microscopic analysis. The paper contains an analysis of lane characteristics through flows, speeds, densities, and headway variations and also investigates the influence of ramp flows on mainline flows with space-time diagrams. Firstly, the merging area in this study is divided into three sections: before-merging, during-merging, and after-merging. The transition process was analyzed at each lane. Secondly, the breakdown was observed in detail with data divided in 50-foot units. The breakdown was checked through the relationships between ramp and freeway mainline flows, various techniques were proposed to analyze the breakdown, and the formation of breakdown was introduced as three stages in this study. In the near future, the findings of this study could contribute to determining the dynamic capacity on freeways by easily understanding changeable traffic breakdown patterns over time and space.

• Proceedings of the KOR-KST Conference
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• 1998.10b
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• pp.191-191
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• 1998

ITS를 구성하는 서비스나 기능이 대부분 동적인 특성을 지니고 있어, 앞으로는 이를 효율적으로 뒷받침할 수 있는 공간데이터(Spatial Data)가 필요하다. 특히, 대부분의 ITS서비스와 기능이 정보의 신속한 전달을 위해서 유무선통신을 사용할 것이다. 또한, 최정 사용자서비스와 응용분야가 공간데이터라는 기본적인 정보를 공유하므로써 위치에 대한 정적·동적교통정보를 제공받게 된다. 정보사용자가 사용하는 공간데이터가 상이하다면, 정보의 공유가 이루어지지 않거나 정확하게 제공되지 않는 것은 자명한 사실이다. 이러한 이유는 정보사용자가 자신들의 정보수집, 정보전달, 정보분석 등의 목적에 적합한 공간데이터를 제작하여 유지하기 때문이다. 결과적으로 정보의 공유를 위해서는 상이한 공간데이터들 간에 동일한 교통정보를 공유하도록 하는 조작이나 방법이 필요하다. 서로 다른 원본으로 구성된 데이터를 통합하고 이를 ITS서비스와 기능을 위한 각 시스템에 적용하기 위해서는 서로 다른 수준을 가지고 있는 공간데이터(수치지도 데이터)의 해상도, 위치정확도, 속성정확도, 정밀도, 범위 등과 같은 문제들이 최종 응용시스템에 적용되어져야 하고, 이를 통해 공간적인 위치와 수치지도를 구성하는 각종 엔터티가 참조되어야 할 것이다. 이뿐 아니라, 향후 데이터 공유의 방법에 있어서도, 각종 무선통신의 발달과 인터넷과 같은 정보전달매체의 대중화가 이루어짐에 따라, 정보의 공유가 동시적으로 이루어질 것이다. 본 연구에서는 공공기관주도로 제작된 전국범위의 수치지도를 하여, ITS용 네트워크데이터구성을 위한 기능분석과 사양을 제시를 함으로써, 이에 대한 프로파일 개발한다. 정보공유를 위한 위치참조모델(LRM)과 프로파일을 ITS데이터에 적용함으로써, 위치참조모델의 기능과 적용성을 평가한다.키기 위한 향후의 연구과제를 제시한다.Si결정의 크기를 비교하였을 때 45$\mu\textrm{m}$ 이하의 분말을 섞어 압출하였을 때 가장 작은 초정 Si입자 크기를 얻음 을 볼 수 있었다. 주의 Fairfax County에 소재한 주간 고속도로 66번(I-66)과 인접 교통망의 교통자료를 사용하여 각종 돌발교통 혼잡 상황을 전제로 한 Traffic Simulation과 정보제공시나\리오를 INTEGRATION Model을 이용해 실행하였다. 그 결과 적응형 알고리즘이 개개인의 최단시간 경로를 제공하는 사용자 평형 경로안내전략에 비해 교통혼잡도와 정체시간의 체류정도에 따라 3%에서 10%까지 전체통행시간을 절약할 수 있다는 결론을 얻었다.출발참, 구성대외개방선면축심, 실현국제항선적함접화국내항반적전항, 형성다축심복사식항선망; 가강기장건설, 개피포동제이국제기장건설, 괄응포동개발경제발전적수요. 부화개시일은 각 5월 26일과 5월 22일이었다. 11. 6월 중순에 애벌레를 대상으로 처리한 Phenthoate EC가 96.38%의 방제가로 약효가 가장 우수하였고 3월중순 및 4월중순 월동후 암컷을 대상으로 처리한 Machine oil, Phenthoate EC 및 Trichlorfon WP는 비교적 약효가 낮았다.>$^{\circ}$E/$\leq$30$^{\circ}$NW 단열군이 연구지역 내에서 지하수 유동성이 가장 높은 단열군으로 추정된다. 이러한 사실은 3개 시추공을 대상으로 실시한 시추공 내 물리검층과 정압주입시험에서도 확인된다.. It was resulted from increase of weight of single cocoon. "Manta"2.5ppm produced 22.2kg of cocoon. It

• Proceedings of the KOR-KST Conference
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• 1998.10b
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• pp.295-295
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• 1998

고속도로에서 교통류의 특성에 파악하여 교통류의 특성을 파악하여 동적행태로 교통상황을 분석하고 효과적인 제어전략, 시뮬레이션, 그리고 기하구조 개선등의 효율적이고 실용적인 적용을 위해서는 교통류의 정확한 모사가 필요하다. 시공간으로 표현되는 상태방정식을 포함하는 거시적 시뮬레이션 모델에 사용되는 연속류 모델은 이러한 교통류 특성을 모사하는데 적절하다. Lighthill과 Whitham(1955), Richard(1956)에 의해 일계도함수의 형태를 가지는 단순모델이 제시된 이후 모델의 결점을 보완하기 위해 많은 고계도 모델이 제시되었지만 고계도 모델이 가진 이론적인 결점에 대해서는 여러 연구들이 제시되어 있다. 또한 고계도 모델은 운동량 방정식의 유도, 정산, 구현의 어려움으로 널리 사용되기 힘들다는 단점을 가지고 있다. 만일 적절히 구현할 수 있다면 적용이 간단한 단순모델로도 보다 정확한 교통류 상황 모사가 가능하다. Ansorge는 혼잡교통류상황을 보다 정확하게 모사하기 위해 단순모델에 엔트로피 조건을 결합시킨 모델을 제시했다. Bui는 이 제안된 모델이 적절한 시뮬레이션 결과를 나타낸다는 것을 밝혔다. 그러나 이 모델은 차량의 재가속이 이루어지는 교통상황-stop-start wave의 경우 비현실적인 값을 가진다. 엔트로피조건에 의해 구해진 해는 실제보다 과다한 교통량을 추정하게 되는데 이런 결과는 위와 같은 교통상황에서 중요한 요소로 작용하는 가속효과가 무시되고 있기 때문이다. 따라서 본 연구에서는 stop-start wave 조건에서 가속도에 경계치를 부여하여 교통류율을 상한경계조건을 제시함으로써 교통상황에 맞는 교통류율을 산정하는 방법에 대해 제안하고자 한다.환승이라는 특정대안변수(Specific alternative variable)를 첨가하여 그것이 수단선택에 미치는 영향을 분석한다. 또한, 대중교통의 속성을 가지고 있는 지하철과 버스를 하나의 대안으로 묶어서 효용함수를 구한 다음 다시 승용차, 택시, 대중교통을 독립된 대안으로 두고 모형을 정립하는 NESTED LOGIT모형으로 파라메타를 추정하여 대중교통의 효용에 관해 분석·비교하였다. 본 논문에 이용된 자료는 공항을 이용하는 이용객들을 대상으로 직접 설문·면접조사한 자료이며 대상 교통수단은 승용차, 택시, 지하철, 버스로 설정하였다. 결과 적응형 알고리즘이 개개인의 최단시간 경로를 제공하는 사용자 평형 경로안내전략에 비해 교통혼잡도와 정체시간의 체류정도에 따라 3%에서 10%까지 전체통행시간을 절약할 수 있다는 결론을 얻었다.출발참, 구성대외개방선면축심, 실현국제항선적함접화국내항반적전항, 형성다축심복사식항선망; 가강기장건설, 개피포동제이국제기장건설, 괄응포동개발경제발전적수요. 부화개시일은 각 5월 26일과 5월 22일이었다. 11. 6월 중순에 애벌레를 대상으로 처리한 Phenthoate EC가 96.38%의 방제가로 약효가 가장 우수하였고 3월중순 및 4월중순 월동후 암컷을 대상으로 처리한 Machine oil, Phenthoate EC 및 Trichlorfon WP는 비교적 약효가 낮았다.>$^{\circ}$E/$\leq$30$^{\circ}$NW 단열군이 연구지역 내에서 지하수 유동성이 가장 높은 단열군으로 추정된다. 이러한 사실은 3개 시추공을 대상으로 실시한 시추공 내 물리검층과 정압주입시험에서도 확인된다.. It was result

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.10 no.4
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• pp.11-23
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• 2011

The objective of this paper is to develop a daily pattern clustering algorithm using historical traffic data that can reliably detect under various traffic flow conditions in urban streets. The developed algorithm in this paper is categorized into two major parts, that is to say a macroscopic and a microscopic points of view. First of all, a macroscopic analysis process deduces a daily peak/non-peak hour and emphasis analysis time zones based on the speed time-series. A microscopic analysis process clusters a daily pattern compared with a similarity between individuals or between individual and group. The name of the developed algorithm in microscopic analysis process is called "Two-step speed clustering (TSC) algorithm". TSC algorithm improves the accuracy of a daily pattern clustering based on the time-series speed variation data. The experiments of the algorithm have been conducted with point detector data, installed at a Ansan city, and verified through comparison with a clustering techniques using SPSS. Our efforts in this study are expected to contribute to developing pattern-based information processing, operations management of daily recurrent congestion, improvement of daily signal optimization based on TOD plans.

• The Korean Journal of Nuclear Medicine Technology
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• v.17 no.2
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• pp.31-36
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• 2013

Purpose: Measure gastric emptying time (GET: Gastric Emptying Time) is a non-invasive and quantitative evaluation methods, mainly by endoscopic or radiological examination confirmed no mechanical obstruction in patients with symptoms of congestion is checked. Such tests are not common gastric emptying time measured esophageal cancer patients (who underwent esophagectomy) patients after surgery for gastric emptying time was measured test. And the period of time for more than one year after the gastric emptying time measurement was performed. By comparing the two kinds of tests in the chest cavity after surgery as the evaluation of gastrointestinal function tests evaluate the usefulness of GET, and will evaluate the characteristics of the image. Materials and Methods: 93 patients who underwent esophagectomy with gastric emptying time measurement of subject tests immediately after surgery and after 1 year or longer were twice. Preparation of the patient before the test is more than 12 hours of overnight fasting is important, in addition to the medicine or to stop smoking, and diabetes insulin injections should be early in the morning is ideal to test. Generally labeled with $^{99m}Tc-DTPA$ resin which is used to make steamed egg, seaweed and fermented milk with a high viscosity after eating, three hours in the standing position was measured. Evaluation of gastric emptying curves on the way intragastric radioactivity level by 50% the time (half-time [T1/2]) was calculated, based on the half-life was divided into three steps: over 180 minutes was defined as delayed gastric emptying, within 180minutes was defined as intermediate gastric emptying and when all the radioisotopes were dumped into the jejunum as soon as swallowed, was defined as rapid gastric emptying. Results: Gastric emptying time of a typical images stomach of antrum and fundus additional images appear stronger over time move on to the small intestine. but esophageal cancer who underwent esophagectomy side of the thoracic cavity showed a strong image. Immediately after surgery, the half-time (T1/2) of rapid gastric emptying appeared to 12.9%, intermediate gastric emptying appeared to 52.7%, delay gastric emptying appeared to 34.4%. After more than a year the results of the half-life after surgery, 67% of rapid gastric emptying to intermediate gastric emptying was changed, 69% of delay gastric emptying to intermediate gastric emptying changed. Intermediate gastric emptying worse in patients rapid gastric emptying and the delay gastric emptying is 24% in the case. Conclusion: Esophagectomy for esophageal cancer who underwent half-time measurement test (T1/2) rapid gastric emptying and delay gastric emptying are the result of the comparison over time, changes were observed intermediate gastric emptying. Mainly seeing of gastric emptying time measurement in the esophagus instead of thoracic cavity to check the evaluation of gastrointestinal function can be useful even means. And segmentation criteria and narrow time interval of checking if more accurate information and analysis of the clinical diagnosis and evaluation seems to be done.