• Investigative Magnetic Resonance Imaging
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• v.2 no.1
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• pp.89-95
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• 1998

Purpose : To investigate the phosphorus metabolic abnormalities in skeletal muscle of patients with mitochondrial myopathy using in vivo $^{31}P$ magnetic resonance spectroscopy(MRS). Materials and Methods : Patients with mitochondrial myopathy(N=10) and normal control subjects (N=10) participated. All in vivo $^{31}P$ MRS examinations were performed on 1.5T whole-body MRI/MRS system by using an image selected in vivo spectroscopy (ISIS) pulse sequence that provided a $4{\times}4{\times}4{\;}cm^{3}$ volume of interest (VOI) in the right thigh muscle tissue. Peak areas for each phophorus methabolite were measured using a Marquart algorithm. Results : The specific features in patients with mitochondrial myopathy were a significant increase of Pi/PCr ratio (p=0.003) and a significant decrease of ATP/PCr ratio (p=0.004) as compared with normal controls. In particular, the ${\beta}-ATP/PCr$ ratio between controls and patients with mitochondrial myopathy was predominantly altered. Conclusions : In vivo $^{31}P$ MRS may be a useful modality in the clinical evaluation of patients with mitochondrial myopathy based on ATP/PCr and Pi/PCr ratios in skeletal muscle tissue and provides a valuable information in further understanding disorders of muscle metabolism.

• Investigative Magnetic Resonance Imaging
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• v.6 no.1
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• pp.64-72
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• 2002

Purpose : To introduce and demonstrate the advantages of the new hybrid two-dimensional (2D) proton spectroscopic imaging (SI) over the single voxel spectroscopy (SVS) and conventional 2D SI in the clinical application of spectroscopy for pediatric cerebral disease. Materials and Methods : Eighty-one hybrid 2D proton spectroscopic imaging was performed in 79 children (36 normal infants and children, 10 with hypoxic-ischemic injury, 20 with toxic-metabolic encephalopathy, seven with brain tumor, three with meningoencephalitis, one with neurofibromatosis, one with Sturge-Weber syndrome and one with lissencephaly) ranging in age from the third day of life to 15 years. In adult volunteers (n=5), all three techniques including hybrid 2D proton SI, SVS using PRESS sequence, and conventional 2D proton SI were performed. Both hybrid 2D proton SI and SVS using PRESS sequence were performed in clinical cases (n=). All measurements were performed with a 1.5-T scanner using standard head quadrature coil. The 16$\times$16 phase encoding steps were set on variable field of view (FOV) depending on the size of the brain. The hybrid volume of interest inside FOV was set as $75{\times}75{\times}15{\;}\textrm{mm}^3$ or smaller to get rid of unwanted fat signal. Point-resolved spectroscopy (TR/TE=1,500 msec/135 or 270msec) was employed with standard chemical shift selective saturation (CHESSI pulses for water suppression. The acquisition time and spectral quality of hybrid 2D proton SI were compared with those of SVS and conventional 2D proton SI. Results : The hybrid 2D proton SI was successfully conducted upon all patients.

• Investigative Magnetic Resonance Imaging
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• v.10 no.1
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• pp.26-31
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• 2006

Purpose : To evaluate the effect of global scaling analysis on brain activation for sensory and motor functional MR imaging study. Materials and methods : Four normal subjects without abnormal neurological history were included. Arm extension-flexion movement was used for motor function and 1KHz pure tone stimulation was used for auditory function. Functional magnetic resonance imaging was performed at 3T MRI (GE, Milwaukee, USA) using BOLD-EPI technique and SPM2 was employed for data analysis. On data analysis, the brain activation images were obtained with and without global scaling by fixing other parameters such as motion correction and realignment. Results : The difference in brain activation between no scaling and global scaling was not large in case of right upper extremity movement (p<0.000001). For auditory test, brain activation with global scaling showed larger activation than that of without global scaling (p<0.05). Conclusion : A caution must be taken into account when analyzing functional imaging data with global scaling especially for functional study of small local BOLD signal change.

• Journal of the Korean Child Neurology Society
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• v.26 no.4
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• pp.280-283
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• 2018

Magnetic resonance imaging (MRI) is recommended for patients with epileptic seizures to rule out an underlying focal lesion. However, abnormalities in idiopathic generalized epilepsy, including childhood absence epilepsy, cannot usually be identified using brain imaging modalities such as MRI. Peri-ictal MRI abnormalities have been most commonly reported secondary to status epilepticus and are rarely observed in patients with focal seizures and generalized tonic-clonic seizures. Transient peri-ictal MRI abnormalities in absence epilepsy are extremely rare. A five-year-old girl presented with a three-day history of absence seizures that persisted despite continued treatment with sodium valproate. Electroencephalography showed bursts of generalized 3-Hz spike-and-wave discharges, during and after hyperventilation. Abnormal cortex thickening in the left perisylvian region was detected on T2-weighted brain MRI, and cortical dysplasia or a tumor was suspected. The patient started treatment with lamotrigine and was seizure-free after one month. The abnormal MRI lesion was completely resolved at the two-month follow-up. We report on a patient with childhood absence epilepsy and reversible brain MRI abnormalities in the perisylvian region. To our knowledge, this is the first report of transient MRI abnormalities after absence seizures. Transient peri-ictal MRI abnormalities should be considered for differential diagnosis in patients with absence seizures and a focal abnormality on brain MRI.

• The Journal of the Acoustical Society of Korea
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• v.14 no.6
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• pp.5-12
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• 1995

In this paper, acoustic analysis of thermoacoustic refrigerating system was given and the design procedure meeting the specifications was presented. The thermoacoustic refrigerator transforms the sound wave energy into the thermal energy via adiabatic process of inert gas. The system is composed of mainly three parts ; the acoustic motor utilizing loudspeaker the stack of plate for thermal transport and the resonator to form the standing wave. Based upon the acoustic analysis, resonator dimension and stack position and size were decided, and the entire refrigerating system was designed to the given specification. Also the mechanical Impedance of the designed resonator was obtained by simulation.

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.1 no.2
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• pp.94-111
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• 2008

Traditionally the diagnosis and treatment of the diseases of the knee is based on the findings of the x-rays and the MRI. The x-rays provide good information of the changes of the internal structure of the bone. However, there is a limitation in providing information of the soft tissue and the cartilage. The MRI is one of the most expensive diagnostic modalities and it can not give us a dynamic and real time information. The sonography has a role in diagnosis and treatment of the soft tissue disease and surface of the bone. It gives us a real time dynamic information and it is really cheap. In this article the sonographic findings of the normal and pathologic conditions of the knee joint are introduced in relation to the findings of the x-rays and the MRI.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2004.07a
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• pp.519-522
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• 2004

첨가제로 $Bi2O_3$를 첨가하고, 소결 온도를 변화시켜 고주파 내역에서 전자기적 특성이 안정적으로 유지될 수 있는 Ni-Zn 페라이트를 제조하고자 하였다. $Bi2O_3$의 첨가는 액상을 형성하여 소결을 촉진시키며, 0.3 wt% 첨가된 시편에서는 비정상 입자를 성장시켜 높은 전력 손실 특성을 나타내었다. 그러나 $Bi2O_3$의 적정한 첨가는 소결을 촉진시켜 밀도를 증가시키며, 균일한 입자를 형성하여 전력 손실이 감소하였다. Ni-Zn 페라이트에 $Bi2O_3$의 첨가는 공명 주파수 범위의 제어가 가능하며, 소결 촉진 및 밀도의 증가를 가져와 안정적인 재료를 제조할 수 있었다. 투자율의 일정성이 특정 주파수 10MHz 부근에서 급증하면서 급감하는 것은 공명이 생기고, 이러한 현장은 자벽 공명 또는 자벽의 이동에 의해 나타나는 것으로 보여진다.

• Korean Journal of Optics and Photonics
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• v.9 no.4
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• pp.236-239
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• 1998

We constructed a frequency doubler with a frequency-stabilized Nd:YAG Laser, a nonlinear crystal KTP, and an external resonant cavity. Using type II phase-making method and a resonant cavity, one usually have a serious problem that the second harmonic conversion efficiency is decreased greatly, for under usual circumstances ordinary ray and extraorninary ray cannot be resonated in a cavity simultaneously. With the change of temperature and incident angle of KTP, we found an optimized condition for the phase-matching and double-resonance. As a result we produced 26 mW of green light with 318 mW of fundamental laser power from a cw Nd:YAG laser.

• Journal of Korean Orthopaedic Sports Medicine
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• v.10 no.2
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• pp.124-128
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• 2011

Many types of meniscal anomalies have been reported. The authors encountered one case of anomalous insertion of the anterior horn of the medial meniscus to the anterior horn of the lateral meniscus, which ran up along the course of the transverse ligament. This anomalous band was detected in MRI of the knee as a horizontal tear of anterior horn of the lateral meniscus but found during the operation as a anomalous insertion of the anterior horn of the medial meniscus. We report the case with a review of the literature.

• 전자공학회논문지 IE
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• v.43 no.4
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• pp.21-27
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• 2006

This paper is for the segmentation and volume calculation of the white matter and gray matter from brain MRI. We segment white matter, gray matter and CSF from the Brain image in the normal and abnormal person, and calculate the volume of segmented tissue. In this paper, we present a new method of extracting white matter, gray matter and CSF and calculation its volume from MR images for brain. And we have developed the determining method of threshold that can extract white matter and gray matter from MR image for brain through the analysis of gray values represented by ratio of each component. We proposed the calculation method of volume for white matter and gray matter by using number of extracted pixels in each slice. This algorithm input CSF/Head volume ratio and age of patient and calculates discriminant value through discriminant expression, classifies normal and abnormal using calculated discriminant value. As a result, we could blow that white matter and gray matter volume decrease and CSF volume increase as we grow gold.