• Investigative Magnetic Resonance Imaging
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• v.9 no.2
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• pp.117-133
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• 2005

For identifying the pathological findings in magnetic resonance images (MRIs), normal anatomical structures in MRIs should be identified in advance. For studying the anatomical structures in MRIs, a learning tool that includes the followings is necessary. First, MRIs of the entire body; second, horizontal, coronal, and sagittal MRIs; third, segmented images corresponding to the MRIs; fourth, three dimensional (3D) images of the anatomical structures in the MRIs; fifth, software incorporating the MRIs, segmented images, and 3D images. Such a learning tool, however, is hard to obtain. Therefore, in this research, such a learning tool which helps medical students and doctors study the normal anatomical structures in MRIs was made as follows. A healthy young Korean male adult with standard body shape was selected. Six hundred thirteen MRIs of the entire body were scanned (slice thickness 3 mm, interslice gap 0 mm, field of view 480 mm${\times}$480 mm, resolution 512${\times}$512, T1 weighted), and transferred to the personal computer. Sixty anatomical structures in the MRIs were segmented to make segmented images. Coronal, sagittal MRIs and coronal, sagittal segmented images were made. On the basis of the segmented images, forty-seven anatomical structures 3D images were made by manual surface reconstruction method. Software incorporating the MRIs, segmented images, and 3D images was composed. This learning tool that includes horizontal, coronal, sagittal MRIs of the entire body, corresponding segmented images, 3D images of the anatomical structures in the MRIs, and software is expected to help medical students and doctors study the normal anatomical structures in MRIs. This learning tool will be presented worldwide through Internet or CD titles.

• The Journal of Korean Society for Radiation Therapy
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• v.19 no.1
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• pp.7-17
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• 2007

Purpose: As increasing complexity of modern radiotherapy technique, more developing dosimetry is required. Polymer gel dosimeters offer a wide range of potential applications with high resolution and assured quality in the thee-dimensional verification of complex dose distribution such as intensity-modulated radiotherapy (IMRT). The purpose of this study is to find the most sensitive and suitable gel as a dosimeter by varying its composition ratio and its condition such as temperature during manufacturing. Materials and Methods: Each polymer gel with various ratio of composition was irradiated with the same amount of photon beam accordingly. Various polymer gels were analyzed and compared using a dedicated software written in visual C++ which converts TE images to R2 map images. Their sensitivities to the photon beam depending on their composition ratio were investigated. Results: There is no dependence on beam energy nor dose rate, and calibration curve is linear. Conclusion: The polymer gel dosimeter developed by using anti-oxidant in this study proved to be suitable for dosimetry.

• Investigative Magnetic Resonance Imaging
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• v.16 no.2
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• pp.173-176
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• 2012

We report the radiological findings of regional enhancement of the liver adjacent to the right adrenal pheochromocytoma. CT and MRI showed focal strong enhancement of adjacent liver tissue in the arterial phase. However during the delayed phase, the lesion showed iso-attenuation with normal hepatic parenchyma and not delineated. The lesion did not show abnormal signal intensity on neither T1 nor T2 weighted images and indistinguishable from normal parenchyma. The enhancing hepatic lesion was spontaneously regressed on postoperative follow up CT which was taken several months after the adrenalectomy.

• Journal of the Korean Society of Radiology
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• v.8 no.5
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• pp.255-260
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• 2014

The acute lumbar pain patients who were unavoidable to take MRI examination were made to take altered lateral recumbent position. they were also not able to control their painfulness and to be in supine position. In this study, it is supposed to increase success rate of the MRI examination through taking the altered lateral recumbent position in using spine and body matrix coil. This altered position made relaxing lumber pain and fatigue for the patients who suffered from sever lumber pain. In these reasons, it decreases the motion artifacts through correcting uncomfortable posture. As a result, qualitative analysis for the image quality was estimated to have average points of supine position A group(lateral recumbent position) of normal candidates and B group(lateral recumbent position) of the abnormal candidates who have sever pain at 4.64, 3.44, and 3.40, respectively. In conclusion, while qualitative analysis in the examination with supine position of the normal patients had significantly high points, the qualitative analysis in the examination with lateral recumbent position of the normal patients and abnormal patients who had sever lumbar pain was almost same. In addition, it was judged that radiologists' imagery interpretation had no other problems in the image evaluation of B group who had acute lumbar pain of abnormal patients. Hereupon, if this technique becomes generalized for the patients who suffer from supine position in the examination, it is supposed to be useful in medical field.

• Investigative Magnetic Resonance Imaging
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• v.3 no.1
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• pp.28-40
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• 1999

MRI는 주로 부인과 질환의 진단에 이용되어 왔으나 뛰어난 연조직 대조도와 다면 영상 능력으로 남성 골반강의 평가에서도 그 활용이 점차 확대되고 있다. 남성 골반강 MRI는 전립선을 중심으로 발전되어 왔으나 음경과 음낭, 요도 등을 침범한 외상, 종양 등의 질환에 매우 유용하므로 이들 부위에서의 MRI 이용이 더욱 증가할 것으로 보인다. 여기서는 전립선, 음경, 음낭 등의 남성 골반강 장기를 평가하는데 필요한 검사기법, 정상 해부학, 이상 질환의 MRI 소견 등에 대해 기술하고자 한다.

• Proceedings of the KSMRM Conference
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• 2001.11a
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• pp.149-149
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• 2001

목적： Birdcage coil보다 SNR이 높은 Surface coil을 이용하여 시각 자극에 대한 반응 정도의 차이를 보이고자 한다. 대상 및 방법： 연구 개발 중인 Magnum 3.0T로 영상을 얻었다. 실험 대상자는 정상인 지원자로 하였고, 10Hz로 깜박거리는 발광다이오드를 이용하여 시각 자극을 실행하였다. 일정 paradigm으로 얻어진 영상은 SPM으로 분석하였다.

• The Korean Journal of Rheology
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• v.4 no.2
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• pp.148-160
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• 1992

폴리프로필렌(PP)과 폴리에틸렌(PE)혼합물의 용융방사에 있어서 불안정성을 연구하 였으며 혼합물의 유변학적 성질, 혼합물의 형태학적 특성과 연신공명과의 관계를 고찰한 것 이다. 신장점도는 spinline rheometer를 사용하여 측정하여 섬유직경은 광센서를 이용하여 방사공정에서 on-line 측정하였고 연신공명의 주기는 Fourier 변환을 이용하여 분석하였다. PP와 PE혼합물의 용융방사에 있어서 PP 함유량이 많을수록 연신공명이 발생하는 임계연신 비가 줄어들고 그 주기는 길어진다. 정상상태에서 구한 유변학적 성질을 이용하여 Shah와 Pearson의 이론식과 Fisher와 Denn의 이론식으로부터 구한 임계연신비값이 실험치와 많은 차이를 보여주었다. 연신공명에 의하여 형성된 섬유의 가는 부분의 배향도는 굵은 부분에 비하여 크게 향상되었으며 PP 함유량이 많을수록 배향도가 크게 증가하였다.

• Proceedings of the KSMRM Conference
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• 2001.11a
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• pp.103-103
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• 2001

목적： 기능적 자기공명영상을 이용하여 숫자 연산과 연관된 뇌영역을 알아보고자 하였다. 대상 및 방법： 정상 성인 자원자 6명을 대상으로 연산과제를 이용하여 연산과제와 관계된 대뇌영역 꼭 활성화를 유도하였다. 실험은 실험 I과 실험II로 나누어 진행하였다. 실험 I에서 연산과제는 스크린을 통해 보여주고 계산식이 맞는지를 판단하여 신호하도록 하였고[예：(4＋5)$\times$8=72], 대조과제는 십자모양을 집중하여 보도록 하였다. 실험II에서 연산과제는 실험 I과 동일하였고, 대조과제는 화면에 제시되는 세 개의 수가 모두 홀수 또는 짝수일 때 신호하도록 하였다. 기능적 자기공명영상은 1.5T 초전도 자기공명영상장치에서 EPI BOLD 기법을 이용하여 얻었으며 6명에서 얻은 영상을 정상화(normalize)한 후 SPM 프로그램을 이용하여 통계분석을 하였다. 활성화된 뇌 영역은 모형뇌에 지도화하여 두 과제에서 활성화된 뇌 영역을 비교 분석하였다.

• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.94-94
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• 2003

목적： 기능적 자기공명영상과 확산텐서영상기법을 이용하여 전음성 난청과 감각신경성 난청에서의 뇌활성화 양상 그리고 청신경경로상의 차이점을 비교 연구하고자 하였다. 대상 및 방법： 전음성 난청군 (n=4)과 감각신경성 난청군(n=5) 그리고 정상군(n=5)에서의 기능적 자기 공명영상과 확산텐서영상을 획득하였다. 기능적 자기공명영상의 경우 1.5T Siemens MR scanner에서 BOLD 기법을 이용하여 500 Hz 순음 청각자극에 대한 뇌활성화 영역을 검출하였고 영상촬영시 발생하는 기계적 소음을 차폐하기 위한 청각자극기를 특별히 제작하여 사용하였다. 뇌백질신경로를 영상화하는 확산텐서영상은 3.0T GE whole body MR scanner를 사용하였으며 미세한 확산운동을 검출하기 위해 초고속 영상기법인 EPI 기법을 사용하였다. 영상의 화질을 높이기 위해 공간적으로 25개의 다른 방향으로 확산경사자장을 가하였다. 청신경로의 비등방성 영상, 신경로 방향 영상등을 구현하기 위해 획득한 확산영상들에 대한 영상 후처리과정을 시행하였다.

• Investigative Magnetic Resonance Imaging
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• v.8 no.1
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• pp.17-23
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• 2004

Purpose : To evaluate changes in total cerebral blood flow (tCBF) with aging, parenchymal volume changes and vascular abnormalities, using 2 dimensional (D) phase-contrast magnetic resonance imaging (PC MRI). Materials and Methods : Routine brain MRI including T2 weighted image, time-of-flight (TOF) MR Angiography (MRA) and 2D PC MRI were performed in 73 individuals, including 12 volunteers. Normal subjects (12 volunteers, and 21 individuals with normal MRI and normal MRA) were classified into groups according to age (18-29, 30-49 and 50-66 years). For the group with abnormalities in brain MRIs, cerebral parenchymal volume changes were scored according to the T2 weighted images, and atherosclerotic changes were scored according to the MRA findings. Abnormal groups were classified into 4 groups: (i) mild reduction in volume, (ii) marked reduction in volume by parenchymal volume and atherosclerotic changes, and (iii) increased volume and (iv) Moya-moya disease. Volumetric flow was measured at the internal carotid artery (ICA) and vertebral artery bilaterally using the velocity-flow diagrams from PC MRI, and combined 4 vessel flows and tCBF were compared among all the groups. Results : The age-specific distribution of tCBFs in normal subjects were as follows: $12.0{\pm}2.1ml/sec$ in 18-29 years group, $11.8{\pm}1.9ml/sec$ in 30-49 years group, $10.9{\pm}2.2ml/sec$ in 50-66 years group. The distribution of tCBFs in the different subsets of the abnormal population were as follows: $9.5{\pm}2.5ml/sec$ in the group with mild reduction in volume, $7.6{\pm}2.0ml/sec$ in the group with marked reduction in volume, and $7.3{\pm}1.2ml/sec$ and $7.0{\pm}1.1ml/sec$ in the increased parenchymal volume and Moya-moya disease groups respectively. Conclusion : Total cerebral blood flow decreases with increasing age with a concomitant reduction in parenchymal volumes and increasing atherosclerotic changes. It is also reduced in the presence of increased parenchymal volume and Moya-moya disease.2D PC MRI can be used as a tool to evaluate tCBF with aging and in the presence of various conditions that can affect parenchymal volume and cerebral vasculature.