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Evaluation of Toxicological Data on Food Additives and Guideline for ADI establishment - Polydimethylsiloxane as emulsifier - (식품첨가물의 독성자료 고찰과 ADI 평가지침 - 소포제 Polydimethylsiloxane를 사례로 -)

  • Choi, Chan-Woong;Jeong, Ji-Yoon;Park, Hyoung-Su;Moon, Jin-Hyun;Lee, Kwang-Ho;Lee, Hyo-Min
    • Journal of Food Hygiene and Safety
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    • v.24 no.4
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    • pp.352-356
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    • 2009
  • The purpose of this study was to introduce the toxicological study review to evaluate the safety of PDMS on the 69th JECFA meeting. Polydimethylsiloxane is a polymer and its ADI was established at 23rd JECFA meeting in 1979. The ADI was maintained although the specification was expanded at its 26th, 29 th, 37 th meetings. Recently, it was reported that PDMS with low molecular weight and viscosity has high absorption rate and different toxicity, so it was submitted at 69th meeting. Toxicological studies of PDMS were submitted from the sponsor and additional information is collected from a document searching. The toxicological studies were reviewed in accordance with the 'Guidelines for the preparation of toxicological working papers for the Joint FAO/WHO Expert Committee on Food Additives'. In the available acute, sub-chronic and chronic toxicity studies on PDMS, dose-related increases in incidence and severity of ocular lesions(corneal crystal, inflammation of the corneal epithelium etc.) were consistently observed after oral dosing. It seems to be a local irritant effect, but the mechanism by which the ocular lesions arose is unclear, although the lack of absorption of PDMS indicates that it is unlikely to be a direct systemic effect. Consequently, the relevance of the ocular lesions for food use of PDMS could not be determined. The ADI of PDMS was re-established from 0-1.5 mg/kg bw/day to 0-0.8 mg/kg bw/day by applying additional safety factor 2 based on its ocular toxicity. The result of 0-0.8 mg/kg bw/day is a temporary ADI until further data are provided to 2010.

재래닭 생산물의 소비형태에 관한 조사연구

  • 한성욱
    • Proceedings of the Korea Society of Poultry Science Conference
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    • 1998.04a
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    • pp.51-86
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    • 1998
  • $\bigcirc$ 재래닭 생산물의 소비 및 구매형태 등에 대한 조사에서 종합적인 결론은 최종 소비자의 응답자는 총 2,250명이었으며 연령, 성별, 직업, 거주지, 주거형태, 가족수, 소득분포등이 비교적 다양하게 분포되어 있다. 판매업소의 특성은 지역별, 매장면적, 업주연령, 성별, 경력등에서 매장위치는 약 60%가 농촌이고 관광지 21.3%, 도시 19.0%순이였으며 매장 면적은 10-30평이 66.9%, 경력은 3년이하 27.4%, 3-5년 22.7%, 5-10년 22.2%였다. $\bigcirc$ 재래닭고기의 소비형태에서 육류선호도는 쇠고기, 돼지고기, 닭고기 순이였으며 재래닭고기의 소비형태에서 전체 응답자의 64.4%가 먹어본 경험이 있었다. 주로 섭취시기는 74.5%가 여름철에 식구들과 같이 회식할 때 식사대용이나 부식용으로 섭취하였다. 소비자가 재래닭고기를 좋아하는 이유는 고기가 쫄깃쫄깃하여 씹는맛과 지방이 적으며 단백한 맛 때문에 독특해서 좋아한다고 하였으며, 싫어하는 이유는 너무 질기고 고기의 양이 너무 적다는 의견이 많았다. 선호하는 요리방법은 백숙, 삼계탕이었고 좋아하는 부위는 역시 다리부위였다. 재래닭고기의 섭취량에 대하여는 1회에 2인이 1마리를 먹는다가 36.4%, 3인이 1마리 31.8%로서 68.2%가 2-3인이 1마리를 먹는다고 하였으며, 가족구성원 중에는 가장이 제일 선호하는 것으로 나타났다. $\bigcirc$ 음식점에서 판매되는 요리한 재래닭의 1마리 가격에 대한 의견은 84.5%가 20,000원정도면 부담이 없이 먹겠다고 하였다. $\bigcirc$ 재래닭의 구입행동에서 구입주체는 주부였으며, 구입장소는 농.축협의 슈퍼와 정육점이었고 백화점과 재래닭 사육장에서 직접구입도 하고 있었다. 구입 동기는 가족들이 좋아하고 영양가를 생각한다가 62%였으며 구입정보는 주위사람의 권유로 구입하고 있었다. $\bigcirc$ 구입할 때 중점적으로 살펴보는 사항은 신선도와 순수재래종 여부, 위생상태였다. 한편 소비자가 언제나 구입할 수 없다는 의견이 85.2%나 되어 원활한 공급과 시장조성이 아직 정착되지 않고 있었다. $\bigcirc$ 현재 유통되고 있는 재래종닭은 소비자 대부분이 잡종으로 인식하고 있었으며, 재래종과 일반육계와의 구별은 깃털색, 피부색, 정강이색등 외관상으로 구별하고 있었다. 체중에 대한 반응은 너무 작다는 의견이었고, 식품으로의 인식도는 비교적 고급식품으로 인식하고 있다. $\bigcirc$ 재래종닭고기의 브랜드화에 대한 견해는 젊고 소득이 높은 계층에서 브랜드화의 필요성을 강조하고 있다. $\bigcirc$ 재래종달걀의 소비형태는 대부분의 소비자가 좋아하였으나 아직 먹어보지 못한 응답자가 많았다. 재래종달걀의 맛에 대해서는 고소하고 독특하여 차별성을 느끼고 있었다. $\bigcirc$ 재래종달걀의 구입장소는 계란판매점(축협.농협), 슈퍼, 백화점, 재래닭 사육 농장등 다양하였으며 포장단위는 10개를 가장 선호하였고, 포장재료는 종이, 플라스틱, 짚의 순으로 좋아하였다. $\bigcirc$ 달걀의 가격은 200원정도를 적정하다고 하였으며, 크기는 (평균 52g)는 가장 적당하다고 인식하고 있으며, 난각색은 대부분의 응답자가 갈색을 선호하였다. $\bigcirc$ 재래종달걀의 구입시 애로사항은 믿을수 없고, 구입장소를 몰라서, 값이 싸다 등이었고, 앞으로 신뢰할 수 있고 위생적인 생산 및 유통체계가 확립될 경우 더 많이 소비하겠다는 의견이었다. $\bigcirc$ 재래닭 판매업소(식당)의 판매형태는 66.7%인 대부분의 업소가 잡종과 개량종 유색닭을 판매하고 있었으며, 1개 업소에서 1일 판매수수는 5-10수의 영세한 판매형태였고, 계절적으로는 여름철에 대부분을 판매하였다. $\bigcirc$ 식당에서 판매하는 재래닭고기의 요리 종류는 주로 백숙이었고, 삼계탕, 닭볶음도 있었으며, 요리된 재래닭 1마리 가격은 20,000원 이상이었으며, 20,000원이하로 판매하는 잡종이 많았다. $\bigcirc$ 재래닭 판매업소에서 재래닭을 구입하는 방법은 재래닭 사육농장에서 1회에 수십마리 구입하여 판매업소의 간이 사육장에서 기르면서 판매하는 업소가 49.6%, 도계된 재래닭을 구입하여 판매하는 업소 26.9%, 직접 재래닭을 사육하면서도 도계하여 판매하는 업소가 21.7%였다. 판매업소에서의 재래닭 사육기간은 90일 이상이었으며 대부분의 업주는 야산에서 방사한 것을 좋게 생각하고 있었다.

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Analysis of the Efficiency of Gyeonggi-do Senior Welfare Centers by DEA Model (DEA를 이용한 경기도 노인복지관 효율성 분석)

  • Kim, Keum Hwan;Pak, Ae Kyung;Ryu, Seo Hyun;Lee, Nam Sik
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.8 no.3
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    • pp.165-177
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    • 2013
  • The purpose of this study was to examine the efficiency of senior welfare centers and the cause of differences among senior welfare centers in that regard, and to investigate influential factors for the differences in efficiency and the size of the influence of the factors. What methods would be effective at assessing the efficiency of senior welfare centers by taking into account their circumstances was reviewed, andpost-hoc analyses were made by using data envelopment analysis(DEA) and DAE/AP Modified prosthetic which were useful tools to evaluate relative efficiency. After 20 senior welfare centers located in Gyeonggi-do were selected, their yearly operating data of 2009 were utilized. The purpose of this study was to examine the efficiency of senior welfare centers. The evaluation data released by the Gyeonggi Welfare Foundation were analyzed by DEA, which is one of nonparametric statistics, and it was possible to obtain significant results on the regional operating efficiency of social welfare centers in 14 metropolitan cities and provinces, the causes and degree of their inefficiency and what areas one could refer to. As the data for the counties were utilized in this study, it's not quite possible to produce accurate results on the relative efficiency of senior welfare centers, but this study could be said to be of significance in that it suggested how to evaluate the overall operating efficiency of senior welfare centers in the counties involving the degree of their operating inefficiency, what improvements should be made and what reference groups there might be and provided information on the usefulness of the DEA model.

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Effect of Water Activity and Temperature on Growth, Germination, Sporulation, and Utilization of Carbon Source of Penicillium oxalicum (PENOX) as a Biocontrol Agent(BCA) for control of Clover(Trifolium repens L.) (토끼풀(Trifolium repens L.) 방제용 생물제제 Penicillium oxalicum (PENOX)의 발아, 생장, 포자생성 및 탄소원이용에 미치는 수분활성 및 온도의 영향)

  • Lee, Hyang-Burm;Kim, Chang-Jin
    • The Korean Journal of Pesticide Science
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    • v.4 no.3
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    • pp.68-74
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    • 2000
  • Penicillium oxalicum (PENOX) has shown the potential as a biocontrol agent(5CA) for control of a weed, clover(Trifolium repens L.) in grass plots. The bioherbicidal activity may be due to germinative and growth capacities and substrate availability of the agent over a range of environmental factors. The influences of different water activities($0.94{\sim}0.995\;a_w$) and temperatures($18{\sim}30^{\circ}C$) on mycelial growth, conidial germination, sporulation oil 2% MEA(malt extract agar) adjusted to different water activities with glycerol, and carbon source utilization using BIOLOG GN MicroPlate were determined in vitro. Decreases in $a_w$ on MEA caused a reduction in mycelial growth and conidial germination depending on temperature. The mycelial growth of PENOX was greatest at $30^{\circ}C/0.995\;a_w$. At some lowered water activity($0.97\;a_w$), the growth was similar between 25 and $30^{\circ}C$, and considerably decreased at lowered temperature($20^{\circ}C$). The germination rate was also greatest at $30^{\circ}C/0.995\;a_w$. Lag phase times for PENOX at $18^{\circ}C$ on MEA were >6hrs at tile whole $a_w$ level tested, and at 18 and $25^{\circ}C$ they were >18hrs and >12hrs at $0.94\;a_w$, respectively. However, its sporulation was some better at $0.97\;a_w$ than $0.995\;a_w$ or $0.94\;a_w$, and better at $20^{\circ}C$ than $30^{\circ}C$. In contrast, the number of carbon sources(niche size) utilized by PENOX varied with $a_w$ and temperature. Under some water stress condition($0.95\;a_w$), the agent utilized smaller number of carbon sources than $0.995\;a_w$ depending on temperature. The niche size at 0.995 and $0.95\;a_w$ were highest at $25^{\circ}C$, and showed 86 and 65, respectively. At $30^{\circ}C$, the niche size at 0.995 and $0.95\;a_w$ showed 84 and 50, respectively. There was no carbon source utilized by PENOX at $0.90\;a_w$ regardless of temperature. These information of tile fungal ecophysiology will be useful for the effective development of BCA.

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Acorn Production and Characteristics of Quercus acuta Thunb - Focused on Wando, Jindo and Haenam in Jeollanam-do, Korea - (붉가시나무의 종실 생산량 및 형질특성 - 전라남도 완도, 진도, 해남을 중심으로 -)

  • Kim, Sodam;Park, In-Hyeop
    • Korean Journal of Environment and Ecology
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    • v.35 no.6
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    • pp.621-631
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    • 2021
  • The purpose of this study is to survey and analyze acorn production and characteristics of the Quercus acuta Thunb. according to the need for information on seed supply and seedling cultivation during the restoration of warm broad-leaved forests. For the survey, a total of 30 seed traps with a surface area of 1 m2 were set up, 3 in each of 10 quadrats (8 in Wando, 1 in Haenam, and 1 in Jindo). The acorns that fell in the seed trap at the end of each month were collected from August to December each year between 2013 to 2016. The collected acorns were then classified into sound, damaged, decayed, or empty grade, and the number of acorns produced was calculated. In the case of sound acorns, acorn traits, such as length, diameter and weight of acorns without cupule, were measured. Duncan's multiple tests of acorn production and characteristics were conducted for comparative analysis of the annual average values with the values by year, stand, month, and treatment plot. The annual number of acorn dropped into the seed traps in each quadrat from 2013 to 2016 was 5-350 acorns/3 m2 in 2013, 17-551 acorns/3 m2 in 2014, 5-454 acorns/3 m2 in 2015, and 14-705 acorns/3 m2 in 2016. There was a large difference in acorn production between the quadrats, presumably attributed to the difference in the amount of light received due to the density of trees in the square. Annual acorn production per area was 335,000 acorns/ha in 2013, 932,000 acorns/ha in 2014, 556,000 acorns/ha in 2015, and 1,037,000 acorns/ha in 2016. That was a sharp variation of acorn production in the two-year cycle. As the fluctuation in the production of Q. acuta showed simultaneity between stands, it is judged that Quercus acuta Thunb. had a clear cycle of fruitfulness and fruitiness between forest objects. September showed the biggest amount of fallen acorns and largest damage from insect pests, indicating that preventing early fall of acorns could increase the fruiting period and enable mass production of sound acorns. There was no significant difference between annual average acorn length in each region. In the case of the acorn diameter and weight, the average values of acorns from Haenam were significantly higher than those from Wando and Jindo. There was no significant difference in the average annual acorn characteristics by month, and the average annual acorn length, diameter, and weight in November were 19.72mm, 12.23mm, and 1.64g, respectively, the highest between August and November.

Analysis of the mixing effect of the confluence by the difference in water temperature between the main stream and the tributary (본류와 지류의 수온 차에 의한 합류부 혼합 양상 분석)

  • Ahn, Seol Ha;Lee, Chang Hyun;Kim, Kyung Dong;Kim, Dong Su;Ryu, Si Wan;Kim, Young Do
    • Journal of Korea Water Resources Association
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    • v.56 no.2
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    • pp.103-113
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    • 2023
  • The river confluence is a section in which two rivers with different topographical and hyrodynamic characteristics are combined into one, and it is a section in which rapid flow, inflow of sediments, and hydrological topographic changes occur. In the confluence section, the flow of fluid occurs due to the difference in density due to the type of material or temperature difference, which is called a density flow. It is necessary to accurately measure and observe the confluence section including a certain section of the main stream and tributaries in order to understand the mixing behavior of the water body caused by the density difference. A comprehensive analysis of this water mixture can be obtained by obtaining flow field and flow rate information, but there is a limit to understanding the mixing of water bodies with different physical properties and water quality characteristics of rivers flowing with stratigraphic flow. Therefore, this study attempts to grasp the density flow through the water temperature distribution in the confluence section. Among the extensive data of the river, vertical data and water surface data were acquired, and through this, the stratification phenomenon of the confluence was to be confirmed. It was intended to analyze the mixed pattern of the confluence by analyzing the water mixing pattern according to the water temperature difference using the vertical data obtained by measuring the repair volume by installing the ADCP on the side of the boat and measuring the real-time concentration using YSI. This study can supplement the analysis results of the existing water quality measurement in two dimensions. Based on the comparative analysis, it will be used to investigate the current status of stratified sections in the water layer and identify the mixing characteristics of the downstream section of the river.

Preoperative Evaluation for the Prediction of Postoperative Mortality and Morbidity in Lung Cancer Candidates with Impaired Lung Function (폐기능이 저하된 폐암환자에서 폐절제술후 합병증의 예측 인자 평가에 관한 전향적 연구)

  • Perk, Jeong-Woong;Jeong, Sung-Whan;Nam, Gui-Hyun;Suh, Gee-Young;Kim, Ho-Cheol;Chung, Man-Pyo;Kim, Ho-Joong;Kwon, O-Jung;Rhee, Chong-H.
    • Tuberculosis and Respiratory Diseases
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    • v.48 no.1
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    • pp.14-23
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    • 2000
  • Background: The evaluation of candidates for successful lung resection is important. Our study was conducted to determine the preoperative predictors of postoperative mortality and morbidity in lung cancer patients with impaired lung function. Method; Between October 1, 1995 and August 31, 1997, 36 lung resection candidates for lung cancer with $FEV_1$ of less than 2L or 60% of predicted value were included prospectively. Age, sex, weight loss, hematocrit, serum albumin, EKG and concomitant illness were considered as systemic potential predictors for successful lung resection. Smoking history, presence of pneumonia, dyspnea scale(l to 4), arterial blood gas analysis with room air breathing, routine pulmonary function test were also included for the analysis. In addition, predicted postoperative(ppo) pulmonary factors such as ppo-$FEV_1$ ppo-diffusing capacity(DLco), predicted postoperative product(PPP) of ppo-$FEV_1%{\times}$ppo-DLco% and ppo-maximal $O_2$ uptake($VO_2$max) were also measured. Results: There were 31 men and 5 women with the median age of 65 years(range, 44 to 82) and a mean $FEV_1$ of $1.78{\pm}0.06L$. Pneumonectomy was performed in 14 patients, bilobectomy in 8, lobectomy in 14. Pulmonary complications developed in 10 patients; cardiac complications in 3, other complications(empyema, air leak, bleeding) in 4. Twelve patients were managed in the intensive care unit for more than 48 hours. Two patients died within 30 days after operation. The ppo-$VO_2$max was less than 10 ml/kg/min in these two patients. MVV was the only predictor for the pulmonary complications. However, there was no predictor for the post operative death in this study. Conclusions: Based on the results, MVV was the useful predictor for postoperative pulmonary complications in lung cancer resection candidates with impaired lung function In addition, ppo-$VO_2$max value less than 10 ml/kg/min was associated with postoperative death, so exercise pulmonary function test could be useful as preoperative test. But further studies are needed to validate this result.

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