• The Korean Journal of Nuclear Medicine
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• v.35 no.5
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• pp.334-341
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• 2001

Purpose: Ascorbic acid us known to act as an antioxidant. Therefore, it can be used in increasing the efficiency of radiochemical labeling of Technetium-99m setamibi by inhibition of oxidation of $Sn^{2+}$ at low concentration. We intended to estimate the efficiency of radiochemical labeling and the stability of the newly formed formulation when ascorbic acid was added to a commercial kit. Materials and Methods: Synthesis of sestamibi was performed according to Dong-A's patent procedure (No.10-2001-0012877). First, we undertook a study to evaluate the efficiency of radiochemical labeling of sestamibi containing ascorbic acid. The stability of the vials was assessed using either $7.5{\mu}g\;or\;75{\mu}g$ of ascorbic acid, added to commercial vials under the accelerated condition(Temp : $40^{\circ}C{\pm}2^{\circ}C$, Relative humidity : $75{\pm}5%$). Results: Sestamibi was synthesized in overall 35-40% yield over 5 steps from a commercially available methallyl chloride as a starling material. When ascorbic acid was added, the efficiency of radiochemical labeling was maintained compared to the vial with no ascorbic acid. The accelerated test showed that the addition of ascorbic acid inhibited the oxidation of $Sn^{2+}$ ion by antioxidation mechanism. Also, the efficiency of radiochemical labeling of this vial after 9 months was nearly the same as the starting point. Therefore, the storage period of the kit is likely to be extended. Taken together, it suggests that the addition of ascorbic acid as a stabilizer is desirable. Conclusion: To increase the stability of a sestamibi cold kit, it is desirable to add ascorbic acid as a stabilizer to the commercial formulation.

• Clinical and Experimental Pediatrics
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• v.45 no.9
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• pp.1114-1119
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• 2002

Purpose : The purposes of this study were to determine short- and long-term fractal correlation behavior of heart rates during daily activity in patients with neurocardiogenic syncope. Methods : Twenty five patients with histories of neurocardiogenic syncope episodes were included. Their analogue 24h ambulatory Holter electrocardiograms were analyzed. The tape was digitized and the digitized electrocardiograms were partioned into sections of one hour. Then their RR intervals were measured and 20,000 points of RRI were used. To quantify the fractal correlation behavior, we employed the detrended fluctuation analysis, and short-term($n{\leq}16$, ${\alpha}_1$) and long-term(n>16, ${\alpha}_2$) fractal scaling exponents were calculated. Results : When compared to control, 24-hour average values of ${\alpha}_1$ and all ${\alpha}_1$ values at quarters of each day were significantly higher in patients with syncope. On the contrary, their 24-hour average value of ${\alpha}_2$ and all ${\alpha}_2$ values at quarters of each day were lower in patients with syncope. However, statistical significances were found in 24-hour average value of ${\alpha}_2$ and in ${\alpha}_2$ value at MN-6AM. Conclusion : In the syncope patients with neurocardiogenic syncope, short-term fractal scaling exponents of RR interval was significantly high throughout the day. Therefore, their RR intervals were smoother in the short term scale and had a tendency to continue in the same direction of increase or decrease, which may contribute to persistent decrease in heart rate during a syncopal attack.

• Journal of Korea Water Resources Association
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• v.54 no.9
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• pp.731-745
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• 2021

In this study, the monthly temperature of the Han River basin was predicted by statistical multiple regression models that use global climate indices and weather data of the target region as predictors. The optimal predictors were selected through teleconnection analysis between the monthly temperature and the preceding patterns of each climate index, and forecast models capable of predicting up to 12 months in advance were constructed by combining the selected predictors and cross-validating the past period. Fore each target month, 1000 optimized models were derived and forecast ranges were presented. As a result of analyzing the predictability of monthly temperature from January 1992 to December 2020, PBIAS was -1.4 to -0.7%, RSR was 0.15 to 0.16, NSE was 0.98, and r was 0.99, indicating a high goodness-of-fit. The probability of each monthly observation being included in the forecast range was about 64.4% on average, and by month, the predictability was relatively high in September, December, February, and January, and low in April, August, and March. The predicted range and median were in good agreement with the observations, except for some periods when temperature was dramatically lower or higher than in normal years. The quantitative temperature forecast information derived from this study will be useful not only for forecasting changes in temperature in the future period (1 to 12 months in advance), but also in predicting changes in the hydro-ecological environment, including evapotranspiration highly correlated with temperature.

• Journal of Korean Society of Forest Science
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• v.81 no.4
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• pp.337-345
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• 1992

In this research, a kinematic wave model was applied for the runoff analysis, Regulation of streamflow was estimated by the calibration of roughness coefficient as a parameter. The data analyzed were obtained from Ananomiya and Shirasaka experimental basins at Tokyo University Forest in Aichi. Estimation methods and characteristics of roughness coefficient as a evaluation method of hydrological function of forest are summarized as follows ; 1. Roughness coefficient($N_s$) indicates the resistance of hillslope to the flowing water of surface runoff. There exists an hypothesis that resistance of hillslope to flowing water increase with the growth forest and development of the $A_o$ layer. 2. Roughness coefficient($N_s$) was estimated by the parameter when the stream direct runoff was calculated by using the kinematic wave. 3. Secular change of '$N_s$' in ananomiya has a curve which has an upper limit and increases exponentially near the limit. The curve quickly increased from 1935 to 1945 when results of afforestation for erosion control were thought to be effective. On the other hand, slight increase of '$N_s$' in Shirasaka indicates that there was not such a big change in the surface of soil layer. 4. The increase of '$N_s$' was related with decrease of direct runoff and increase of base flow. It was recognized that the rate of direct runoff decreased with the improvement of forest physiognomy and the rate of base flow was increased. But absolute value of water runoff per one storm decreased in chronological order.

• Journal of Conservation Science
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• v.36 no.2
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• pp.73-81
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• 2020

Considering the difficulties associated with the creation of deterioration maps for stone cultural heritages, quantitative determination of chemical and biological contaminants in them is still challenging. Hyperspectral image analysis has been proposed to overcome this drawback. In this study, hyperspectral imaging was performed on Stone Buddhas Temple in Four Directions at Gulbulsa Temple Site(Treasure 121), and several surface contaminants were observed. Based on the color and shape, these chemical and biological contaminants were classified into ten categories. Additionally, a method for establishing each class as a reference image was suggested. Simultaneously, with the help of Spectral Angle Mapper algorithm, two classification methods were used to classify the surface contaminants. Method A focused on the region of interest, while method B involved the application of the spectral library prepared from the image. Comparison of the classified images with the reference image revealed that the accuracies and kappa coefficients of methods A and B were 52.07% and 63.61%, and 0.43 and 0.55, respectively. Additionally, misclassified pixels were distributed in the same contamination series.

• Tunnel and Underground Space
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• v.27 no.1
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• pp.39-49
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• 2017

The factor of safety (FOS) is commonly used as an index to quantitatively state the degree of safety of various rock structures. Therefore it is important to understand the definition and characteristics of the adopted FOS because the calculated FOS may be different according to the definition of FOS even if it is estimated under the same stress condition. In this study, four local factors of safety based on maximum shear stress, maximum shear strength, stress invariants, and maximum principal stress were defined using the Mohr-Coulomb and Hoek-Brown failure criteria. Then, the variation characteristics of each FOS along five stress paths were investigated. It is shown that the local FOS based on the shear strength, which is widely used in the stability analysis of rock structures, results in a higher FOS value than those based on the maximum principal stress and the stress invariants. This result implies that the local FOS based on the maximum shear stress or the stress invariants is more necessary than the local FOS based on the shear strength when the conservative rock mechanics design is required. In addition, it is shown that the maximum principal stresses at failure may reveal a large difference depending on the stress path.

• Korean Journal of Environment and Ecology
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• v.34 no.2
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• pp.170-178
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• 2020

There are few landscape ecological analyses of Khingan fir (Abies nephrolepis) and other habitats of the sub-alpine zone in South Korea. In this study, we tried to quantitatively interpret and assess the habitat characteristics by analyzing 15 landscape indices according to the differences in tree layer coverage, in the Khingan fir habitat growing naturally in the sub-alpine zone of Seoraksan National Park. It was difficult to identify the tendency of landscape ecology to increase and decrease the tree layer coverage in the study site, which was the entire Khingan fir habitat in Seoraksan National Park. However, the Khingan fir habitat was found to be generally low in coverage, and population density as the tree layer coverage of less than 50 percent accounts for 85 percent of the total habitat. Moreover, the Khingan fir habitat in the 10 to 50 percent range was fragmented into a total of 286 patches, making it relatively less connected to the habitat. The total edge length and edge density, which could determine the edge effect of the main part according to the physical form, were the highest in the habitat of 26 to 50 percent coverage, indicating a relatively high impact from outside than habitats of other coverages. The shape with the tree layer coverage of between 10 and 50 percent was more complex even with patches of the same size, and it is believed that these characteristics make it more susceptible to habitat fragmentation and external confounding. We expect that the results of this study can be useful for time series analysis of spatial expansion or reduction of the Khingan fir habitat in Seoraksan National Park and provide the reference data for the morphological change and movement of patches and the connectivity and break-off between forests.

• Journal of the Korean Institute of Landscape Architecture
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• v.51 no.1
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• pp.56-71
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• 2023

Citizens' needs for urban green spaces are on the rise due to improved quality of life and increased interest in environments. The garden is noteworthy because it is small in size, making it less controversial to create in the city, and it is adjacent to the residential area, improving citizens' daily environment. Moreover, recently gardens is attracting attention as a tool for urban regeneration, such as being created in declining areas as part of a government project. Therefore, it is time to study the role and value of urban gardens in deteriorated areas in terms of space welfare. However, there are few studies that quantitatively evaluate the effects of gardens, and many prior studies are limited to focusing the green space larger than a certain size (e.g., parks and forests). Therefore, the aim of this study is to examine the effect of garden and gardening quantitatively, paying attention to social aspects such as life satisfaction and community of inhabitants. The study was conducted in an old row housing complex in Gojan1-dong, Ansan-si, Gyeonggi-do. In there, some of the dwellers voluntarily created outdoor gardens and engaged in gardening for a long time. In addition, after the 2017 Gyeonggi-do Garden Fair, several gardens have been maintained and used by residents there. For the first step, the field trip was done to research the status of the garden in the area, and then, a survey was conducted on whether or not gardening has an impact on the life satisfaction and community of residents. The results were analyzed by t-test and ANOVA. As a result, residents who are engaged in gardening are more active in the "neighborhood exchange" and "resident participation" than those who are not engaged in gardening. In addition, if residents voluntarily create a garden, the level of "satisfaction of life" is higher than those staying in the garden which is constructed by the government. And a resident who is gardening in the complex shows higher life satisfaction than those who garden outside of the complex. These results confirmed that the garden has positive effects promoting "exchanges with neighbors", "participation in the community", and "life satisfaction" of residents. It shows that it is important to ensure the right of residents to participate in the garden-making process as much as possible, and the garden's location should be paid attention to maximize the positive effect of gardens.

• Journal of the Korea Institute of Building Construction
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• v.24 no.1
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• pp.97-108
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• 2024

This research delves into the escalating concerns of accidents and fatalities in the construction industry over the recent five-year period, focusing on the development of a Safety Perception Model to augment safety measures. Given the rising percentage of elderly workers and the concurrent drop in productivity within the sector, there is a pronounced need for leveraging Fourth Industrial Revolution technologies to bolster safety protocols. The study comprises an in-depth analysis of statistical data regarding construction-related fatalities, aiming to shed light on prevailing safety challenges. Central to this investigation is the formulation of a Safety Perception Model tailored for small-scale construction projects. This model facilitates the quantification of safety risks by evaluating safety grades across construction sites. Utilizing the DWM1000 module, among an array of wireless communication technologies, the model enables the real-time tracking of worker locations and the assessment of safety levels on-site. Furthermore, the deployment of a safety management system allows for the evaluation of risk levels associated with individual workers. Aggregating these data points, the Safety Climate Index(SCLI) is calculated to depict the daily, weekly, and monthly safety climate of the site, thereby offering insights into the effectiveness of implemented safety measures and identifying areas for continuous improvement. This study is anticipated to significantly contribute to the systematic enhancement of safety and the prevention of accidents on construction sites, fostering an environment of improved productivity and strengthened safety culture through the application of the Safety Perception Model.

• Korean Journal of Microbiology
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• v.49 no.4
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• pp.424-428
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• 2013

To identify risk factors for Legionella contamination, water quality variables routinely measured in examination of natural and city waters were meta-analyzed for significance of correlation to Legionella incidences. For evaluation of abundance of Escherichia coli as a risk factor, which is currently used as an indicator of Legionella contamination in an official guideline in Korea, odds ratio (OR) of above-cutoff total coliform counts for Legionella presence/absence was used as the effect size in the meta-analysis. The OR was estimated as 1.05 (0.36-3.12, 95% CI), and the probability of having identical odds reached 0.92. Also, ORs from individual studies showed significant heterogeneity (P=0.008), which contributed to 63% of total variance of the ORs. In the case of heterotrophic plate count (HPC), the OR for Legionella presence/absence was 2.72 (2.04-3.63) with highly significant deviation from identical odds (P<0.0001). ORs from different studies were seemingly homogeneous ($Q_{df=8}$=12.7, P=0.12). Turbidity and concentrations of chlorine, iron ion and cupper ion were other routine variables that could be considered as risk factors. However, statistical measures from different studies were not uniform enough to develop an appropriate effect size while the number of studies reporting the variables was also small (3-5). In conclusion, HPC appeared to be appropriate as indicator of Legionella contamination, rather than fecal bacteria contamination. HPC may imply abundance of habitats (amoebas and biofilms) of Legionella in water. This result warrants further studies for standardizing protocols and cutoff values to infer Legionella risks from HPC.