• Title/Summary/Keyword: 정량적 모델

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Anti-Inflammatory and Antioxidative Effects of Acaiberry in Formalin-Induced Orofacial Pain in Rats (흰쥐의 악안면 통증에서 아사이베리의 항염증 및 항산화 효과)

  • Kim, Yun-Kyung;Hyun, Kyung-Yae;Lee, Min-Kyung
    • Journal of dental hygiene science
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    • v.14 no.2
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    • pp.240-247
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    • 2014
  • Acaiberry (Euterpe oleracea Mart.) is widely diffused in amazon and is known that has high antioxidant capacity and potential anti-inflammatory activities. The aim of this study was to evaluate analgesic effects of acaiberry in formalin-induced orofacial pain through p38 mitogen-activated protein kinases (p38 MAPK) and nicotinamide adenine dinucleotide phosphate 4 (NOX4) pathway. Rats were divided into 5 groups (n=6); formalin (5%, $50{\mu}L$), formalin after saline (vehicle) or acaiberry (16, 80, 160 mg/kg, intraperitoneally). The nociceptive response was investigated all of groups, p38 MAPK or NOX4 were analysed at dose of 80 mg/kg of acaiberry in rat's medulla oblongata and adrenal gland. Results indicated that acai berry produced analgesic effect in a dose-dependent manner and significantly reduced formalin-induced nociceptive response at 15~40 min. Acaiberry (80 mg/kg) decreased the increased p38 MAPK activation and NOX4 expression in medulla oblongata and adrenal gland. Based on these results, acaiberry is believed to be useful for modulation of orofacial pain and its treatments because of its anti-inflammatory and antioxidative effects.

A study on the calculation method for the number of vehicles in queue to determine the fire ventilation capacity in road tunnels - forced on the effect of queue length (도로터널의 제연용량 산정을 위한 정체차량대수 산정기법에 관한 연구 - 정체길이를 중심으로)

  • Yoo, Yong-Ho;Kim, Hyo-Gyu;Ryu, Ji-Oh
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.18 no.1
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    • pp.41-52
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    • 2016
  • When the queue length of congestion vehicles in tunnel fire is extended beyond tunnel length, the capacity of smoke control system needs to be increased in line with ventilation resistance. However, the vehicle queue length is not defined, so a rational equation is necessary in current fire prevention guideline. This study is intended to propose an equation to calculate the queue length considering the number of vehicles in queue in tunnel fire and evaluate the applicability by tunnel length as well. When it comes to normal tunnel, it is necessary to compare the vehicle queue length with tunnel length up to the length of 1,200 m in a bid to avoid applying the vehicle queue length excessively in case of fire. As a result of evaluation of applicability to model a tunnel, saving the number of jet fan for smoke control appeared to be effective. Besides, quantitative approach to explain the vehicle queue length through the relationship between the percentage of large vehicles and tunnel length was presented. Consequently, when the queue length of the congestion vehicles exceeds the tunnel length in determining the capacity of smoke control system in case of fire, the number of vehicles beyond the tunnel length needs to be excluded from estimating the ventilation resistance by vehicles.

A Study on Fluid Flow Analysis of High Pressure Positive Displacement Pump without Clearance (클리어런스가 없는 초고압 회전용적형 헬리컬기어 펌프의 유동해석에 관한 연구)

  • Min, Se-Hong;Kim, Ho-Chul
    • Fire Science and Engineering
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    • v.29 no.2
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    • pp.33-38
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    • 2015
  • For the purpose of high-pressure and suction of fixed amount, the development of ultra-high pressure rotating helical gear positive displacement pump with no clearance had been proceeded. The CFD analysis was performed to verify the internal pressure and the discharge flow velocity of the pump. Accordingly, a flow analysis were performed by FVM technique and we were unable to obtain a successful result since the fluid domain is separated because the grid is not configured in a row in FVM flow analysis of the fully enclosed type without clearance. Because of these problems, the flow analysis was performed by MPS method which grid configuration is not needed and the internal pressure and the discharge flow velocity of the pump were confirmed through the MPS flow analysis. At 1,000 rpm rotation speed of the rotor, the minimum internal pressure of the pump was 19.5 bar, maximum pressure was 44.6 bar and average pressure was 33.9 bar. And the minimum discharge flow velocity was 64.5 m/s, maximum discharge flow velocity was 84.8 m/s and average discharge flow velocity was 76.1 m/s. Through this study, we could confirm that MPS method was more suitable than FVM method in terms of flow analysis with no clearance. In addition, the relationship of the flow velocity according to the change of ultra-high pressure rotating helical gear positive displacement pump could be identified through this study.

Numerical experiments for the changes of currents by reclamation of land in Kwangyang Bay (매립으로 인한 광양만의 유동변화 수치실험)

  • 추효상
    • Journal of Environmental Science International
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    • v.11 no.7
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    • pp.637-650
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    • 2002
  • This study presents an investigation of the changes of the currents in Kwangyang Bay due to the construction of harbor, reclamation and coastal developments. Currents were simulated by the numerical experiments with a diagnostic multi-level model and using the seasonal oceanographic data of temperature, salinity and ocean current. The values of kinetic and potential energies for the currents were calculated in cases of three topographical changes; before coastal developments, the existing state and after completion of the development project in Kwangyang Bay. The changes of currents due to the coastal developments are as follow; Kinetic energies of tide induced residual currents and wind driven currents decreased by 35~40 percent and 5 percent respectively, however those of density currents increased by 10 percent since the decrease of the coastal areas. Kinetic energy of residual currents including tide induced residual currents, density currents and wind driven currents reduced by 10 percent compared with before the coastal developments. Decrease of current velocity was greatest in summer. Therefore, in summer it was assumed that the Kwangyang Bay is more easily polluted by stratification and decrease of residual current than before the coastal developments carried out.

A Study of Platform for Management and Real-Time Service of Distributed Objects (분산 객체들의 관리와 실시간 서비스를 위한 플랫폼의 연구)

  • Kim, Myung-Hee;Joo, Su-Chong
    • Proceedings of the Korea Information Processing Society Conference
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    • 2001.10a
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    • pp.297-300
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    • 2001
  • 최근의 컴퓨팅 환경은 이질적인 클라이언트와 서버들간의 상호 운용성을 요구하는 분산 어플리케이션을 위한 프로그래밍 파라다임을 지원하기 위한 분산 객체 컴퓨팅 환경으로 발전되고 있다. 여기에는 복잡한 네트워킹과 다양한 멀티미디어 응용 서비스를 위한 객체지향 기술들이 접목되고 있다. 이러한 분산 컴퓨팅 환경에서 처리되는 어플리케이션들의 실시간 서비스 지원을 위해 요구되는 실시간 특성과 분산 객체들의 관리의 어려움을 해결하기 위하여 본 논문에서는 실시간 객체그룹 플랫폼을 구축한다. 기존의 연구들은 실시간 CORBA를 사용하거나 또는 ORB를 수정하거나 실시간 운영체제상에 특정 CORBA 제품군을 사용하여 분산 환경의 특정 영역의 성능향상만을 도모하고 있다. 그러므로, 본 논문은 ORB의 수정 없이 표준 CORBA상에서 실시간 특성을 지원한 수 있는 실시간 객체그룹 플랫폼을 설계한다. 본 논문의 실시간 객체그룹 구조는 객체들의 관리적인 측면과 실시간 어플리케이션 서비스 지원 측면에 대한 요구사항들을 분석하여 정립한 모델이며, 구성요소들의 기능을 관리와 서비스로 분리하여 각각의 기능수행시에 발생하는 객체간의 상호작용이 다른 기능에 영향을 미치지 않도록 한다. 또한, 구축된 플랫폼은 실시간 어플리케이션 개발자에게 실시간 특성 파라미터의 표현과 처리에 대한 투명성을 부여하여 어플리케이션에 유연성과 확장성을 제공하기가 용이하도록 한다. 따라서, 본 논문은 실시간 객체그룹 플랫폼의 구성요소들에 대한 역할을 정의하고 기능을 정립하며, 각 구성요소들을 설계하고 구현하였으며, 구현되어진 실시간 객체그룹 플랫폼의 기능과 수행 성능을 검증한다.가지 유기화합물 중에서는 35.6%를 차지하였다. BTEX 각각 개별물질은 미국 환경보호청이 제시하는 일일 노출 기준량(Reference Concentration; RfC) 보다는 현저히 낮았다. 총 휘발성 유기화합물읜 농도는 실내가 실외 보다 높았다(I/O ratio 2.5). BTEX의 상대적 함량도 실내가 실외보다 높아 실내에도 발생원이 있음을 암시하고 있다. 자료 분석결과 유치원 실내의 벤젠은 실외로부터 유입되고 있었고, 톨루엔, 에틸벤젠, 크실렌은 실외뿐 아니라 실내에서도 발생하고 있었다. 정량한 8개 화합물 각각과 총 휘발성 유기화합물의 스피어만 상관계수는 벤젠을 제외하고는 모두 유의하였다. 이중 톨루엔과 크실렌은 총 휘발성 유기화합물과 좋은 상관성 (톨루엔 0.76, 크실렌, 0.87)을 나타내었다. 이 연구는 톨루엔과 크실렌이 총 휘발성 유기화합물의 좋은 지표를 사용될 있고, 톨루엔, 에틸벤젠, 크실렌 등 많은 휘발성 유기화합물의 발생원은 실외뿐 아니라 실내에도 있음을 나타내고 있다.>10)의 $[^{18}F]F_2$를 얻었다. 결론: $^{18}O(p,n)^{18}F$ 핵반응을 이용하여 친전자성 방사성동위원소 $[^{18}F]F_2$를 생산하였다. 표적 챔버는 알루미늄으로 제작하였으며 본 연구에서 연구된 $[^{18}F]F_2$가스는 친핵성 치환반응으로 방사성동위원소를 도입하기 어려운 다양한 방사성의 약품개발에 유용하게 이용될 수 있을 것이다.었으나 움직임 보정 후 영상을 이용하여 비교한 경우, 결합능 변화가 선조체 영역에서 국한되어 나타

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Understory Evapotranspiration Measured by Eddy-Covariance in Gwangneung Deciduous and Coniferous Forests (광릉 활엽수림과 침엽수림에서 에디공분산으로 관측한 하부 군락의 증발산)

  • Kang, Min-Seok;Kwon, Hyo-Jung;Lim, Jong-Hwan;Kim, Joon
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.11 no.4
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    • pp.233-246
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    • 2009
  • The partitioning of evapotranspiration (ET) into evaporation (E) and transpiration (T) is critical in understanding the water cycle and the couplings between the cycles of energy, water, and carbon. In forests, the total ET measured above the canopy consists of T from both overstory and understory vegetation, and E from soil and the intercepted precipitation. To quantify their relative contributions, we have measured ET from the floors of deciduous and coniferous forests in Gwangneung using eddy covariance technique from 1 June 2008 to 31 May 2009. Due to smaller eddies that contribute to turbulent transfer near the ground, we performed a spectrum analysis and found that the errors associated with sensor separation were <10%. The annual sum of the understory ET was 59 mm (16% of total ET) in the deciduous forest and 43 mm (~7%) in the coniferous forest. Overall, the understory ET was not negligible except during the summer season when the plant area index was near its maximum. In both forest canopies, the decoupling factor ($\Omega$) was about ~0.15, indicating that the understory ET was controlled mainly by vapor pressure deficit and soil moisture content. The differences in the understory ET between the two forest canopies were due to different environmental conditions within the canopies, particularly the contrasting air humidity and soil water content. The non-negligible understory ET in the Gwangneung forests suggests that the dual source or multi-level models are required for the interpretation and modeling of surface exchange of mass and energy in these forests.

Validation of HPLC Methods for Ascorbic Acid and Its Derivatives in Foods (식품 중 아스코르빈산 유래 산화방지제의 HPLC 분석법 검증 및 개선)

  • Jeong, Min Kyu;Park, Chan Uk;Park, Min Hee;Yeo, JuDong;Park, SeungKwan;Kim, SoHee;Shin, Tae-Sun;Baek, Hyung Hee;Lee, JaeHwan
    • Food Engineering Progress
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    • v.15 no.1
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    • pp.75-79
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    • 2011
  • Analytical methods for food antioxidants including ascorbic acid, erythorbic acid, ascorbyl palmitate (AP), and ascorbyl stearate (AS), were validated using high performance liquid chromatography. Validation parameters such as linearity, limit of detection (LOD), limit of quantification (LOQ), and recovery were tested using lard and cider as food model systems. Linearity of ascorbic acid and erythorbic acid were both higher than ($R^2$> 0.99), LOD of these compounds were 0.46 and 0.48 ${\mu}g/mL$, respectively and LOQ were 1.39 and 1.45 ${\mu}g/mL$, respectively. The recovery rates of these compounds were 86.35-94.78% and 84.76-95.02%, respectively. However, the concentration of AP and AS decreased in methanol stock solution. Four other solvents including ethanol, acetonitrile, mixture of methanol and acetonitrile, and mixture of ethanol and acetonitrile were tested to increase the stability of AP and AS under room temperature and refrigerated temperature. Ethanol provided better stability of AP and AS under both room and refrigerated temperature. This study can help to accurately analyze the content of ascorbic acid and its derivatives in processed foods.

Development of Air Flow Simulator in Agricultural Facility based on Virtual Reality (가상현실 기반 농업시설 공기유동 시뮬레이터의 개발)

  • Noh, Jae Seung;Kim, Yu Yong;Yoo, Young Ji;Kwon, Jin Kyung;Lee, In Bok;Kim, Rack Woo;Kim, Jun Gyu
    • Journal of Bio-Environment Control
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    • v.28 no.1
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    • pp.16-27
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    • 2019
  • Using virtual reality technology, users can learn and experience many interactions in virtual space like the actual physical space. This study was conducted to develop air flow simulator that allows farmers and consultants to consult air flow through VR devices by creating a greenhouse or pigpen model. It can help educate farmers about the importance of ventilation effects for agricultural facilities. We proposed CFD visualization system by building a virtual reality environment and constructing database of CFD and structure of agricultural facilities. After consultants can set up situations according to environmental conditions, the users experience the visualized air flow of agricultural facility according to the ventilation effects. Also it can provide a quantified environmental distribution in the agricultural facility. Currently, the CFD data in agricultural facilities are established during winter and summer. In order to experience various environmental conditions in the developed system, The experts need to run CFD data under various environmental conditions and register them in the system requirements.

Seismic Fragility Evaluation of Bridges Considering Rebar Corrosion (철근 부식을 고려한 교량의 지진취약도 평가)

  • Shin, Soobong;Kong, Sina;Moon, Jiho;Song, Jong-Keol
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.34 no.4
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    • pp.231-241
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    • 2021
  • Although the deterioration of bridges may occur due to various causes, one of the representative causes is that the chloride used for deicing in the winter penetrates bridge members and results in corrosion. This study aims to quantify the ageing degree resulting from the corrosion of a bridge, apply it to the inelastic dynamic analysis model of the bridge, perform a seismic fragility analysis, and evaluate the relationship between the ageing degree and the seismic fragility curve. It is important to appropriately define the threshold values for each damage state in seismic fragility analyses considering the ageing degree. The damage state was defined using the results of existing experimental studies on the characteristics of the deterioration in the displacement ductility capacity of the pier, according to the ageing degree. Based on the seismic fragility analyses of six types of bridges divided by three types of bearing devices and two pier heights, it was found that the seismic vulnerability tends to increase with the ageing degree. The difference in seismic vulnerability with respect to the ageing degree exhibits a tendency to increase as the damage state progresses from slight to moderate, severe, and collapse.

Evaluation of Water Quality Change by Membrane Damage to Pretreatment Process on SDI in Wastewater Reuse (하수재이용에서 전처리 막 손상에 의한 수질변화가 SDI에 미치는 영향평가)

  • Lee, Min Soo;Seo, Dongjoo;Lee, Yong-Soo;Chung, Kun Yong
    • Membrane Journal
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    • v.32 no.4
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    • pp.253-263
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    • 2022
  • This study suggests a guideline for designing unit process of wastewater reuse in terms of a maintenance of the process based on critical parameters to draw a high quality performance of RO unit. Defining the parameters was done by applying membrane integrity test (MIT) in pretreatment process utilizing lab-scale MF. SDI is utilized for judging whether permeate is suitable to RO unit. However, result said TOC concentration matching with particle count analysis is better for judging the permeate condition. When membrane test pressure (Ptest) was measured to derive log removal value in PDT, virgin state of membrane fiber was used to measure dynamic contact angle utilizing surface tension of the membrane fiber. Actually, foulant affects to the state of membrane surface, and it decreases the Ptest value along with time elapsed. Consequently, LRVDIT is also affected by Ptest value. Thus, sensitivity of direct integrity test descends with result of Ptest value change, so Ptest value should be considered not the virgin state of the membrane but its current state. Overall, this study focuses on defining design parameters suitable to MF pretreatment for RO process in wastewater reuse by assessing its impact. Therefore, utilities can acknowledge that the membrane surface condition must be considered when users conduct the direct integrity test so that Ptest and other relative parameter used to calculate LRVDIT are adequately measured.