• The Journal of the Korean bone and joint tumor society
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• v.6 no.1
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• pp.10-16
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• 2000

Object : The aim of the current study is to assess the results of segmental resection and replantation for primary malignant or aggressive tumors of the upper limb. Materials and Methods : From 1986 to 1994, ten patients who had primary malignant or aggressive tumors of the upper limb were managed with segmental resection and replantation method. The average duration of follow-up was 7 years and 7 months. Primary indication of this method is stage II B tumors which, because of their extend, could otherwise be adequately treated only by amputation. Three patients had chondrosarcoma, two had osteosarcoma, two had giant cell tumors with pathologic fracture, one had extensive chondroblastoma, one had Ewings sarcoma, and one had leiomyosarcoma. The location of the tumor was humerus in 6 patients, scapula in 3 patients, and soft tissue of forearm in 1 patient. Wide resection margins were achieved in 7 patients and marginal margin in three. Results : One patient died on 40 months after surgery due to systemic metastasis. Nine patients have remained disease free without local recurrence or metastasis. The average overall functional rating was 65% (43~90%) for ten patients on the last follow-up by the functional rating system of Enneking. The mean grasping power and pinching power of operative hand was 75%(28~95%) and 65%(43~90%) of the opposite hand, respectively. Complications associated with this surgical method included three wound dehiscences and one nerve injury that resolved with proper wound care and time. Conclusion : It was concluded that segmental resection and replantation might be used for partial limb salvage in selected cases for the treatment of primary malignant or aggressive tumors of the upper limb.

• Journal of the Korea Concrete Institute
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• v.22 no.3
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• pp.381-388
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• 2010

In this study, characteristics of the seismic response of the non-earthquake resistant reinforced concrete (RC) frame were identified. The test building is designed to withstand only gravity loads and not in compliance with modern seismic codes. Smooth bars were utilized for the reinforcement. Members are provided with minimal amount of stirrups to withstand low levels of shear forces and the core concrete is virtually not confined. Columns are slender and more flexible than beams, and beam-column connections were built without stirrups. Through the modeling of an example RC frame, the feasibility of the fiber elementbased 3D nonlinear analysis method was investigated. Since the torsion is governed by the fundamental mode shape of the structure under dynamic loading, pushover analysis cannot predict torsional response accurately. Hence, dynamic response history analysis is a more appropriate analysis method to estimate the response of an asymmetric building. The latter method was shown to be accurate in representing global responses by the comparison of the analytical and experimental results. Analytical models without rigid links provided a good estimation of reduced stiffness and strength of the test structure due to bond-slip, by forming plastic hinges closer to the column ends. However, the absence of a proper model to represent the bond-slip poased the limitations on the current inelastic analysis schemes for the seismic analysis of buildings especially for those with round steel reinforcements. Thus, development of the appropriate bond-slip model is in need to achieve more accurate analysis.

• The Korean Journal of Nuclear Medicine
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• v.36 no.6
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• pp.333-343
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• 2002

Purpose: A new linker, hydrazino nicotinamide (HYNIC), was recently introduced for labelling of liposome with $^{99m}Tc$. In this study we synthesized HYNIC derivatized PEG (polyethylene glycol)-liposomes radiolabeled with $^{99m}Tc$. Materials and Methods: In order to synthesize HYNIC-DSPE (distearoyl phosphatidyl ethanolamine) which is a crucial component for $^{99m}Tc$ chelation, first of all succinimidyl 6-BOC-hydrazinopyridine-3-carboxylic acid was synthesized from 6-chloronicotinic acid by three sequential reactions. A DSPE derivative of succinimidyl 6-BOC-hydrazinopyridine-3-carboxylic acid was transformed into HYNIC-DSPE by HCI/dioxane. HYNIC-PEG-liposomes were prepared by hydration of the dried lipid mixture of EPC (egg phosphatidyl choline): PEG-DSPE : HYNIC-DSPE:cholesterol (1.85:0.15:0.07:1, molar ratio). The HYNIC-PEG-liposomes were labeled with $^{99m}Tc$ in the presence of $SnCl_2{\cdot}2H_2O$ (a reducing agent) and tricine (a coligand). To investigate the level of in vivo transchelation of $^{99m}Tc$ in the liposomes, the $^{99m}Tc$-HYNiC-PES-liposomes were incubated with a molar excess of DTPA, cysteine or glutathione solutions at $37^{\circ}C$ for 1 hour. The radiolabeled liposomes were also incubated in the presence of human serum at $37^{\circ}C$ for 24 hours. Results: 6-BOC-hydrazinopyridine-3-carboxylic acid was synthesized with 77.3% overall yield. The HYNIC concentration in the PEG-coated liposome dispersion was 1.08 mM. In condition of considering the measured liposomal size of 106 nm, the phospholipid concentration of $77.5\;{\mu}mol/m{\ell}$ and the liposomal particle number of $5.2{\times}10^{14}$ liposomes/ml, it is corresponded to approximate 1,250 nicotinyl hydrazine group per liposome in HYNIC-PEG-liposome. The removal of free $^{99m}Tc$ was not necessary because the labeling efficiency were above 99%. The radiolabeled liposomes maintained 98%, 96% and 99%, respectively, of radioactivity after incubation with transchelators. The radiolabeled liposomes possessed above 90% of the radioactivity in serum. Conclusion: These results suggest that the HYNIC can be synthesized easily and applied in labelling of PEG-liposomes with $^{99m}Tc$.

• Journal of the Korea Concrete Institute
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• v.27 no.4
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• pp.451-458
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• 2015

The infill-wall strengthening method has been widely used for the seismic performance enhancement of the conventional reinforced concrete (RC) frame structures with non-seismic detail, which is one of the promising techniques to secure the high resisting capacity against lateral forces induced by earthquake. During the application of the infill-wall strengthening method, however, it often restricts the use of the structure. In addition, it is difficult to cast the connection part between the wall and the frame, and also difficult to ensure the shear resistance performances along the connection. In this study, an advanced strengthening method using the externally-anchored precast wall-panel (EPCW) was proposed to overcome the disadvantages of the conventional infill-wall strengthening method. The one-third scaled four RC frame specimens were fabricated, and the cyclic loading tests were conducted to verify the EPCW strengthening method. The test results showed that the strength, lateral stiffness, energy dissipation capacity of the RC frame structures strengthened by the proposed EPCW method were significantly improved compared to the control test specimen.

• Journal of the Korean Recycled Construction Resources Institute
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• v.5 no.3
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• pp.290-297
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• 2017

The flexural behavior tests of UHPC segmental U-girder and composite U-girder which has 160MPa compressive strength and 15.4m length were carried out. The test variables are volume fraction of steel fibers and slab over the U-girder. Each U-girder has longitudinal re-bars in web and lower flange. PS tendons which has 2 of 15.2mm diameter in upper flange and PS tendons which has 7 of 15.2mm diameter in lower flange were arranged and prestressed at onetime in U-girder connection stage. Enough strong prestressing force which applied to U-girder due to ultra high performance concrete strength can withstand the self weight and dead load in U-girder stage. By comparison with the brittle behavior of U-girder, composite U-girder showed the stable and ductile behavior. After the construction of slab over U-girder, flexural load capacity of composite U-girder can bear the design load in final construction stage with only one time prestressing operation which already carried out in U-girder stage. This simple prestressing method due to the ultra high strength concrete have the advantage in construction step and cost. The shear key which has narrow space has the strong composite connection between ultra high strength concrete U-girder and high strength concrete slab didn't show any slip and opening right before failure load.

• Journal of Conservation Science
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• v.35 no.5
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• pp.440-452
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• 2019

This research has analyzed SI, the traditional steel, and SIHS(SI + HS), SICS(SI + CS), and SINiS(SI + NiS), the materials that were produced through welding and reprocessing three modern steel- HS, CS, and NiS- that have different carbon content. The purpose of the analyzation was to improve the definition of the multi-layered pattern that appears in the forging process. In observing modified structures on the commissures of three modern steel that have different carbon component to the SI, SINiS produced the most significant multi-layered pattern as well as the excellent welding quality. The excellent welding quality was due to the content of nickel which helped the forge welding process with other materials. There was no significant difference in crystal grain per materials, and SICS showed the highest hardness. At the measurement of EPMA for commissures of the materials, SINiS showed the highest definition of the multi-layered pattern due to the nickel and carbon content. The results above showed that the carbon steel with nickel content is the best material for the most definite multi-layered pattern, expressed from the multi-layered structure which is a characteristic of traditional forge welding technology. It is expected that the result of this research can be utilized as the technical data in further researches regarding the relics excavated from ancient welding process and their multi-layered structure and patterns.

• Journal of the Korean earth science society
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• v.39 no.3
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• pp.211-227
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• 2018

This study evaluates the prediction skills of stratospheric polar vortex intensification events (VIEs) in Global Seasonal Forecasting System (GloSea5) model, an operational subseasonal-to-seasonal (S2S) prediction model of Korea Meteorological Administration (KMA). The results show that the prediction limits of VIEs, diagnosed with anomaly correlation coefficient (ACC) and mean squared skill score (MSSS), are 13.6 days and 18.5 days, respectively. These prediction limits are mainly determined by the eddy error, especially the large-scale eddy phase error from the eddies with the zonal wavenumber 1. This might imply that better prediction skills for VIEs can be obtained by improving the model performance in simulating the phase of planetary scale eddy. The stratospheric prediction skills, on the other hand, tend to not affect the tropospheric prediction skills in the analyzed cases. This result may indicate that stratosphere-troposphere dynamic coupling associated with VIEs might not be well predicted by GloSea5 model. However, it is possible that the coupling process, even if well predicted by the model, cannot be recognized by monotonic analyses, because intrinsic modes in the troposphere often have larger variability compared to the stratospheric impact.

• Korean Chemical Engineering Research
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• v.44 no.5
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• pp.513-519
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• 2006

We developed two kinds of the microchip for application to electrophoresis based on both glass and quartz employing the MEMS fabrications. The poly-Si layer deposited onto the bonding interface apart from channel regions can play a role as the optical slit cutting off the stray light in order to concentrate the UV ray, from which it is possible to improve the signal-to-noise (S/N) ratio of the detection on a chip. In the glass chip, the deposited poly-Si layer had an important function of the etch mask and provided the bonding surface properly enabling the anodic bonding. The glass wafer including more impurities than quartz one results in the higher surface roughness of the channel wall, which affects subsequently on the microflow behavior of the sample solutions. In order to solve this problem, we prepared here the mixed etchant consisting HF and $NH_4F$ solutions, by which the surface roughness was reduced. Both the shape and the dimension of each channel were observed, and the electroosmotic flow velocities were measured as 0.5 mm/s for quartz and 0.36 mm/s for glass channel by implementing the microchip electrophoresis. Applying the optical slit with poly-Si layer provides that the S/N ratio of the peak is increased as ca. 2 times for quartz chip and ca. 3 times for glass chip. The maximum UV absorbance is also enhanced with ca. 1.6 and 1.7 times, respectively.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.37 no.2
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• pp.5-12
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• 2000

Uncooled metallic thin-film thermopile infrared detectors have been fabricated, and the figures of merit for the detectors were examined. The hot junctions of a thermopile were prepared on a $Si_{3}N_{4}/SiO_{2}/Si_{3}N_{4}$-membrane which acts as a thermal isolation layer, the cold junctions on the membrane supported with the silicon rim which functions as a heat sink, and Au-black was used as an infrared absorber. Infrared absorbance of Au-black, which strongly depends on the chamber pressure during Au-evaporation and its mass per area, was found to be about 90 ％ in the wavelength range from 3${\mu}{\textrm}{m}$ to 14${\mu}{\textrm}{m}$. Voltage responsivity, noise equivalent power, and specific detectivity of Bi-Sb thermopile infrared detector at 5 Hz-chopping frequency were about 10.5V/W, 2.3 nW/Hz$^{1/2}$, 및 $1.9\times10^{7}$ cm.Hz$^{1/2}$/w at room temperature in air, respectively.

• Proceedings of the KWS Conference
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• 2009.11a
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• pp.62-62
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• 2009

석탄화력발전소의 CO2배출량 감소와 고효율, 대용량화로 인해 초초임계압(USC:Ultra Super Critical) 화력발전소의 건설이 증가하고 있다. USC 발전소는 효율향상을 위한 증기온도와 압력의 상승 때문에 보일러 고온고압부에 기존의 소재에 비해 고온강도와 내산화성의 재료물성이 향상된 신소재 적용이 불가피하다. 특히 사용된 신소재 중에서 보일러 본체를 구성하는 수냉벽관(Water wall), 과열기와, 재열기용 튜브 및 후육부인 헤더와 배관재로 기존의 2.25Cr-1Mo강을 개량한 2.25Cr-1.6W계 내열강이 적용되고 있다. 2.25Cr-1.6W강은 SMI와 MHI가 공동개발한 소재로 1995년 튜브제품이, 1999년에 단조, 파이프재, 플레이트제품이 ASME code case로 등재되었고, 2009년 ASME code case 2199-4로 개정되어 사용 중이다. 이 소재는 2.25Cr-1Mo강에 고온강도 개선을 위해 석출강화효과가 있는 V과 Nb을 첨가하였고, 탄화물의 열적안정성과 고용강화효과 증대를 위해 W을 첨가하였다. 그리고 제작성과 용접성 및 재료의 인성 향상을 위해 B첨가와 C함량을 낮추었다. 합금성분의 첨가와 조정에 의해 고온강도는 개선되었지만, 보일러 설치 및 보수를 위한 용접과정에서 용접금속과 CGHAZ(Coarse Grain HAZ)에서 용접균열이 발생하였다. 대부분의 용접균열은 용접결함이나 고온 혹은 저온균열이 아닌 2.25Cr-1.6W계강의 강도 개선을 위해 첨가한 V과 Nb이 용접후열처리 도중 입내에 MX형태의 미세석출로 입내를 강화시킴으로서 발생한 재열균열 민감성 증대에 기인된 것으로 판단된다. 이에 본 연구에서 용접 및 후열처리 과정에서 용접금속과 HAZ에서 발생하는 용접금속의 응력분포를 전산해석을 통해 확인하고 실제 후육파이프 용접부에서 잔류응력을 측정해 비교하였다. 용접부 응력분포는 SYSWELD 프로그램을 사용해 해석을 수행하였고, 발전소 실배관재의 용접부 응력측정은 수평부 측정이 용이하도록 지그를 부착한 Potable 잔류응력측정기를 사용해 Hole Drilling Method(HDM)를 적용하여 잔류응력을 측정하였다. 해석 결과 CGHAZ부위의 잔류응력이 용접금속과 기타 부위에 비해 높은 응력분포를 나타냈으며, 이는 CGHAZ와 용접용융선 부근에서 균열이 발생하는 실제값과 일치하는 결과를 보였다. 실제 배관재 용접부에서 측정한 잔류응력값은 항복응력의 약 50% 이하 응력값을 나타냈다. 배관 구조에 기인한 시스템응력의 영향을 제거하기 위해 배관재 용접부를 중심으로 양끝단을 절단 후 용접부에서 측정한 응력은 항복응력 대비 25%수준의 낮은값을 보였다. 그러나 배관재가 장기간 고온환경에 노출되었고 용접금속 내부의 균열이 발생한 상태에서 측정하였기 때문에 용접잔류응력은 상당부분 해소되어 상대적으로 낮은 응력값이 얻어진 것으로 판단된다.