• Environmental and Resource Economics Review
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• v.17 no.3
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• pp.167-199
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• 2008

There are many successful cases in power interconnection among European and South American countries. However, that is not the case in Northeast Asian countries. Even though there will be a considerable benefit in power interconnection in Northeast Asian countries, there will be some difficulties due to various interest relationship and constraints among countries in Northeast Asia. GTMax(Generation and Transmission Maximization) Program is a very useful tool to analyze competitive electricity market and power interconnection developed by Argonne National Laboratory under the Department of Energy in the USA. This study tried to verify applicability and usefulness by GTMax model to domestic electric power system and power transfer from Russia Far East by power interconnection. When the power by importing from Russia is 2,000MW(around 2% of domestic installed capacity in 2017), there is no impact on domestic electricity market because of small power transfer. The power by importing should be large enough for achieving greater cost reduction by power interconnection. Besides, it would be better to supply power to Kyung-In region directly in reducing overall cost when the power by importing from Russia are sold at low price. In the case of interconnecting Young-Dong region, if it is not possible to upgrade transmission line with power transfer capabilities between Young-Dong and Kyung-In region, then the power by importing from Russia can replace the power produced in Jung-Bu region and the relative benefit of importing power can be reduced.

• Korean Journal of Veterinary Research
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• v.35 no.2
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• pp.405-416
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• 1995

FBs, secondary metabolites of several species of Fusaria, especially Fusarium moniliforme and F proliferatum, are commonly contaminated in com and other food grains throughout the world. Only recently identified, these mycotoxins have been associated field outbreaks of ELEM in horses and PPE in pigs. Currently, naturally or experimentally induced FB toxicosis has been studied in poultry, ruminants and rabbits. Poultry fed FB showed decreased growth rate, performance, and immune competence, as well as embryopathic, and embryocidal effects, and ricktes. Ruminants seem to be relatively less susceptible to FBs than other doestic animal. FB toxicosis reveals that liver is a target organ in all species, although other organs are affected in a species specific manner. Recently, the main target organs for $FB_1$ toxicity in rabbits was shown to be the kidney. Even low concentrations of FBs are likely to be a problem for animal health. A current study being conducted showed that feed containing low level of $FB_1$ reduces the ability of pulmonary intravascular macrophages in pig to clear blood-borne particles which would increase the susceptibility of animals to bacterial disease. The mechanism of FB toxicity remains unknown, but may be related to altered sphingolipid biosynthesis by inhibiting sphinganine N-acyltransferase. Elevations of serum and tissue SA:SO ratio have been observed in horse, pig, chicken, turkey, and rabbit, which could could serve as in effective biomarker for consumption of FB-containing feeds. There is limited information detailing dose-effect relationships either from field cases or in the laboratory. More research on the factors, including the prevalence and tolerance levels of FBs in feedstuffs that cause domestic animal disease associated with FBs, is urgently needed.

• Korean Journal of Clinical Pharmacy
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• v.21 no.3
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• pp.215-223
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• 2011

암로디핀과 레파그리니드의 병용은 당뇨병의 합병증으로인한 고혈압 유발 시 병용 처방될 수 있다. 암로디핀과 레파그리니드의 약동학적 상호작용 연구를 위하여 암로디핀 (0.1 및 0.4 mg/kg) 과 레파그리니드를 흰 쥐에 경구(0.5 mg/kg) 및 정맥 (0.2 mg/kg) 투여하여 연구를 실시하였다. 암로디핀이 cytochrome P450 (CYP) 3A4 활성과 P-glycoprotein (P-gp)의 활성에 미치는 영향도 평가하였다. 암로디핀의 CYP3A4의 50% 효소활성억제는 $9.1{\mu}M$ 이었다. 암로디핀은 P-gp의 활성에는 영향을 미치지 않았다. 암로디핀 (0.4 mg/kg)은 레파그리니드의 혈장곡선하면적(AUC)과 최고혈장농도 ($C_{max}$)를 40.2% 와 22.2% 각각 유의성 (p < 0.05)있게 증가시켰다. 따라서, 레파그리니드의 상대적생체이용률 (RB)은 암로디핀과 병용투여 시 1.18-1.40 배 증가되었으며, 또한 레파그리니드의 절대적생체이용률(AB)은 대조군과 비교하여 41.0% 유의성 있게 증가되었다. 경구 투여 시와는 대조적으로, 암로디핀은 정맥 내로 투여된 레파그리니드에서는 약동학적 파라미터에 어떤 영향도 미치지 않았다. 따라서 암로디핀이 레파그리니드의 생체이용률을 증가시킨 것은 신장배설 감소 또는 P-gp 활성억제 보다는 암로디핀이 소장 또는 간장에서 CYP3A4을 억제시켰기 때문으로 사료된다. 암로디핀과 레파그리니드의 병용투여 시 레파그리니드의 용량을 조절하는 것이 안전하다고 사료된다.

• Applied Chemistry for Engineering
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• v.8 no.3
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• pp.403-409
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• 1997

The equilibrium constants of five deoxyribonucleosides (dDyd, dUrd, dGuo, dThd, dAdo) were estimated by the plate theory and the moment method under isocratic conditions of the Reversed-Phase High Performance Liquid Chromatography (RP-HPLC). The mobile phase in this system was composed of water and organic modifiers(acetonitrile and methanol) The plate theory of linear adsorption isotherm was treated on the basis of continuous flow of eluent through the plates of the column. The moment method was utilized to find the equilibrium constant from the first absolute moment of experimental data. The equilibrium constants of five deoxyribonucleosides in the two methods were very close, and also the equilibrium constants calculated by capacity factor were similar to those by both the plate theory and the moment method. The equilibrium constant was expressed as a semi-log function of the quantity of organic modifier. Excellent agreements between the calculated elusion profile by the plate theory and the experimental data were observed.

• Korean Chemical Engineering Research
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• v.47 no.1
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• pp.54-58
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• 2009

Ketoprofen and ibuprofen are non-steroid anti-inflammatory drug(NSAID) that have analgesic and antipyretic properties. (S)-ketoprofen and (S)-ibuprofen have pharmacological activity, while (R)-ketoprofen and (R)-ibuprofen are either inactive or have side effect. The chiral separation of racemic ketoprofen and ibuprofen enantiomers was carried out by using a Kromasil HPLC column. Some chromatographic parameters (selectivity, resolution, number of theoretical plates and ${\Delta}H$) are calculated under different mobile phase compositions of hexane/t-BME/acetic acid and temperatures. The selectivity, resolution and number of theoretical plates were observed high at $25^{\circ}C$ and the composition of hexane/t-BME/acetic acid (80/20/0.1).

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.173-177
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• 2007

현재 농업용수 이용량은 158억$m^3/yr$로 우리나라 전체 수자원이용량의 48%에 해당되며 하천유지수량을 제외하였을 경우 61%에 해당된다. 농업용수의 이용은 노후화된 농업수리시설과 관리기술 부족 등의 원인으로 이용효율이 낮은 것으로 추정되고 있다. 그러나 이러한 현황을 뒷받침해 줄 측정 및 조사자료가 부족한 실정이다. 농업용수의 물관리 연구는 장기간의 신뢰성 있는 수문자료의 획득이 절대적으로 필요하고 실제 현장에서의 물관리 상황을 조사파악하는 것이 중요한다. 이러한 자료의 축척은 체계적이고 일관되게 수행되어야 한다. 이를 위하여 한국농촌공사에서는 2000년에 경기도 용인에 위치한 이동저수지 유역을 종합시험지구로 선정하여 운영하게 되었다. 이동시험지구는 경기도 용인시, 평택시, 안성시, 사이에 위치한 전형적인 농촌지역이다. 저수지와 양수장 시설이 복합적으로 운영되어 농업용수를 공급하는 지구로 농업용수의 물관리 연구 수행을 위해 적합한 지역이다. 이동시험지구에 강우계, 저수지 수위계, 하천 수위계, 수로 수위계를 설치하여 운영하고 있으며 정기적으로 유지 관리 및 자료수집을 함으로써 신뢰성 있는 농촌지역 수문자료를 축척하고 있다. 이동시험지구의 운영은 농업용수 물관리와 관련된 체계적이고 신뢰성 있는 장기간의 수문자료를 축척하고 축척된 현장 자료의 분석을 통해 물관리 기초자료를 계량화 하는데 그 목적이 있다. 본 연구의 목적은 실제 농업용 저수지의 용수공급 운영에 따라 하천에서의 유출특성에 대한 조사를 통하여, 농업용저수지가 하천에 미치는 영향을 파악하고자 한다. 시험지구 덕성교 하천수위관측지점의 하천유출율은 65 %, 재인교 하천수위관측지점의 경우 하천유출율은 60 %를 나타내었다. 이동유역의 경우 상류에 저수지가 있으며 저수지의 시기별 저수상태와 강우량에 따라 유출에 영향을 받고 있다. 1월에 상류 저수지의 저수상태가 만수를 유지하고 있었으며 예년에 비하여 많은 강우가 발생하여 저수위 조절 차원에서 인위적으로 방류한 양이 많았기 때문으로 추정할 수 있다. 두 지점의 1월 유출이 100 % 이상인 것은 동절기 하천 결빙으로 인한 유량파악이 힘든 것으로 나타났다. 1월의 하천수위는 계측기에 기록된 수위값으로 유량을 산정한 것이다. 3월, 10월, 12월의 유출이 많은 것은 전월말 발생한 강우의 영향으로 크게 나타났다.

• Nuclear Engineering and Technology
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• v.21 no.1
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• pp.12-17
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• 1989

The correction factor of neutron fraction absorbed by $^{55}$ Mn in the MnSO$_4$ bath was determined for the absolute measurement of neutron emission rate by using the solution circulation-type manganese sulfate bath system. For the determination of this correction factor, I/f, the atomic number desnsity and the effective neutron capture cross section data of Mn, S and impurity elements in the MnSO$_4$ solution were determined. For the atomic number density determination, the MnSO$_4$ solution concentration was determined by using the volumetric EDTA titration and gravimetric method. The impurity contents were analyzed by using the ICP method. For the calculation of effective neutron capture cross sections, a FORTRAN computer program EASCAL was developed in this study. in which Westcott's parameters and Axton's empirical relations are used.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.4D
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• pp.573-580
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• 2006

The Saturation headway is a major parameter in estimating the intersection capacity and setting the signal timing. But Existing algorithms are still far from being robust in dealing with factors related to the variation of saturation headways at signalized intersections. So this study apply the fuzzy inference system using ANFIS. The ANFIS provides a method for the fuzzy modeling procedure to learn information about a data set, in order to compute the membership function parameters that best allow the associated fuzzy inference system to track the given input/output data. The climate conditions and the degree of brightness were chosen as the input variables when the rate of heavy vehicles is 10-25 %. These factors have the uncertain nature in quantification, which is the reason why these are chosen as the fuzzy variables. A neuro-fuzzy inference model to estimate saturation headways at signalized intersections was constructed in this study. Evaluating the model using the statistics of $R^2$, MAE and MSE, it was shown that the explainability of the model was very high, the values of the statistics being 0.993, 0.0289, 0.0173 respectively.

• Korean Journal of Soil Science and Fertilizer
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• v.31 no.1
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• pp.16-24
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• 1998

To determine the optimum application of fertilizers for the cultivation of Chinese cabbage in plastic film house, twenty soils which contain different salts contents were taken from 4 different area of plastic film house cultivation, Youngdong. Boeun county, Cheongweon county, and Cheongju city. The dry weight and the amount of N. P, and K uptakes of Chinese cabbage in the plot of no fertilization were considered as the factors representing the fertility of the soil. And a difference of dry weight and the amounts of N, P, and K uptakes of plants between the plot of fertilization and no fertilization were considered as the factors representing the total effect of fertilizer and fertilizer N, P, and K effects. respectively. These factors of soil fertility and fertilizer effects were estimated by correlation and regression with soil tests in order to find the critical levels and recommended method for optimum fertilization of Chinese cabbage. Chinese cabbage transplanted in two soils, having the electrical conductivity of 9.3 and 15.2 dS/m, were not able to root due to the salts toxicity. The content of inorganic N, the electrical conductivity, and CEC were founded to have significant correlation with the factors of both the soil fertility and fertilizer effects for the cultivation of Chinese cabbage. To determine the weighting degree for the productivity and the fertilizer effects, the standardized partial regression coefficient was analyzed by regression among the factors of fertility, the fertilizer effects, and the soil tests. The coefficient for inorganic N($NH_4-N$ and $NO_3-N$) was obtained as the absolute value of 756-1871 and this value was extremely higher than those of other soil tests which was 0.07-4.11. These results suggested that the content of inorganic N is the best tests for the estimation of the productivity and the fertilizer effects for the cultivation of Chinese cabbage in plastic film house. The critical level of inorganic N($NH_4-N+NO_3-N$) estimated by Cate-Nelson split method for maximum productivity and zero point of fertilizer effect was 220 mg/kg for all the factors of estimation. These results suggested that no application of fertilizer N. P, and K is required at the critical level of inorganic N of soil. Consequently the optimum application of fertilizer N, P, and K for the cultivation of Chinese cabbage in plastic film house was possible to determine by the critical level of inorganic N of soil. The critical level of electrical conductivity was estimated as 2.8 dS/m by the same method.

• Journal of the Korea Organic Resources Recycling Association
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• v.26 no.2
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• pp.95-103
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• 2018

As a guideline for desulfurization and dehumidification pretreatment facility for optimizing utilization of biogas, the $H_2S$ concentration is set at 150 % which can be treated with iron salts, dehumidification is the optimum value for generator operation, and the relative humidity applied at the utilization of biogas in EU is set at 60 %. We have set up the generator facility guidelines to optimize utilization of biogas. The appropriate amount of biogas should be at least 90 % of the total gas generation, and the capacity of generator facility should be set at 20~30 %. In order to equalize the pressure of the incoming gas the generator, a gas equalization tank should be installed and the generator room average temperature should be kept at $45^{\circ}C$ or less. Since the gas is not produced at a certain methane concentration in the digester, the efficiency is lowered. Therefore, it is required to install an air fuel ratio control system according to the change in methane concentration. Therefore, it is necessary to compensate for the disadvantages of biogasification facilities of organic waste resources and optimize utilization of biogas and improve operation of facilities. This study was conducted to optimize biogas utilization of type of organic waste(containing sewage sludge and food waste, animal manure), investigate the facilities problem and propose design, operation guidelines such as pre-treatment facilities and generators.