• Journal of Yeungnam Medical Science
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• v.14 no.2
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• pp.459-466
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• 1997

Hyperparathyroidism due to parathyroid cancer is rare. It is difficult to diagnose preoperatively but there should be an increased index of suspicion in those parathyroid patients with palpable neck masses, profound hypercalcemia(greater than 14mg/dl), marked increase of the parathyroid hormone level to greater than twice normal, and significant metabolic complications. In parathyroid cancer, systemic calcinosis is an extremely rare manifestation. The most common metastatic calcification site is lung and the other involved site is stomach, liver, skin and heart. After resection of parathyroid tumor, this systemic calcinosis is self-limiting. We experienced a patient with primary hyperparathyroidsm, presented with metastatic calcification in the lung and stomach disappeared by successful parathyroidectomy.

• Clinical and Experimental Pediatrics
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• v.45 no.10
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• pp.1298-1301
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• 2002

Systemic capillary leak syndrome(SCLS) is a rare disorder of unknown etiology, which is characterized by recurrent attacks of hypotension, hemoconcentration, and hypoalbuminemia. Urinary or enteric loss of protein is not demonstrated. It is often associated with monoclonal gammopathy, but does not manifest multiple myeloma. Since Clarkson et al. described the first case in a 34-year-old woman, about 50 cases have been reported in the literature. However, most of the cases were of adult age, and the mean age of onset in the reported cases was 42.6 years. In literature review, we could refer only one pediatric case of SCLC by Foeldvari et al. in 1995. We report another pediatric case of SCLS.

• Tuberculosis and Respiratory Diseases
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• v.45 no.1
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• pp.153-168
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• 1998

Background: The existing data indicate that obstructive sleep apnea syndrome contributes to the development of cardiovascular dysfunction such as systemic hypertension and cardiac arrhythmias, and the cardiovascular dysfunction has a major effect on high long-term mortality rate in obstructive sleep apnea syndrome patients. To a large extent the various studies have helped to clarify the pathophysiology of obstructive sleep apnea, but many basic questions still remain unanswered. Methods: In this study, the influence of obstructive sleep apnea on systemic blood pressure, cardiac rhythm and urinary catecholamines concentration was evaluated. Over-night polysomnography, 24-hour ambulatory blood pressure and ECG monitoring, and measurement of urinary catecholamines, norepinephrine (UNE) and epinephrine (UEP), during waking and sleep were undertaken in obstructive sleep apnea syndrome patients group (OSAS, n=29) and control group (Control, n=25). Results: 1) In OSAS and Control, UNE and UEP concentrations during sleep were significantly lower than during waking (P<0.01). In UNE concentrations during sleep, OSAS showed higher levels compare to Control (P<0.05). 2) In OSAS, there was a increasing tendency of the number of non-dipper of nocturnal blood pressure compare to Control (P=0.089). 3) In both group (n=54), mean systolic blood pressure during waking and sleep showed significant correlation with polysomnographic data including apnea index (AI), apnea-hypopnea index (AHI), arterial oxygen saturation nadir ($SaO_2$ nadir) and degree of oxygen desaturation (DOD). And UNE concentrations during sleep were correlated with AI, AHI, $SaO_2$ nadir, DOD and mean diastolic blood pressure during sleep. 4) In OSAS with AI>20 (n==14), there was a significant difference of heart rates before, during and after apneic events (P<0.01), and these changes of heart rates were correlated with the duration of apnea (P<0.01). The difference of heart rates between apneic and postapneic period (${\Delta}HR$) was significantly correlated with the difference of arterial oxygen saturation between before and after apneic event (${\Delta}SaO_2$) (r=0.223, P<0.001). 5) There was no significant difference in the incidence of cardiac arrhythmias between OSAS and Control In Control, the incidence of ventricular ectopy during sleep was significantly lower than during waking. But in OSAS, there was no difference between during waking and sleep. Conclusion : These results suggested that recurrent hypoxia and arousals from sleep in patients with obstructive sleep apnea syndrome may increase sympathetic nervous system activity, and recurrent hypoxia and increased sympathetic nervous system activity could contribute to the development of cardiovascular dysfunction including the changes of systemic blood pressure and cardiac function.

• Neonatal Medicine
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• v.16 no.2
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• pp.190-196
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• 2009

Purpose: Candida infection has increased in neonatal intensive care units (NICU). However, recent reports on systemic candida infections in preterm newborns are rare in Korea. The aim of this study was to examine the epidemiological features of systemic candida infection in very low birth weight infants (VLBW) over the past five years. Methods: We retrospectively reviewed the medical records of 19 patients with systemic candida infections in VLBW that were admitted to the neonatal intensive care units of three hospitals affiliated with the College of Medicine, The Catholic University of Korea from January 2004 to December 2008. We analyzed the birth weight, gestational age, age at diagnosis, risk factors, co-morbidity, antifungal treatment, and mortality rates among the 19 patients. Results: Systemic candida infections occurred in 19 cases (4.7%) among the VLBW infants. The mean birth weight and gestational age were 959.0$\pm$255.9 g and 26.7$\pm$2.1 weeks. The isolated Candida species were C. albicans (4), C. parapsilosis (9), C. glabrata (2), C. famata (2), and unkown subspecies (2). Most patients had various associated risk factors, including a central venous catheter, broad spectrum antibiotics, parenteral nutrition, intravenous lipid emulsion, endotracheal intubation and $H_2$ blocker therapy. There was no significant difference in the risk factors between newborns that survived and those that died with regard to the systemic candida infection, except for gestational age. Nine (47.4%) out of 19 patients with a candida infection died and four cases (21.2%) were directly related to the candida infection. Conclusion: The prevalence of systemic candida infection is increasing in VLBW infants. The majority of Candida species has shifted to C. non-albicans, especially C. parapsilosis. Because of the high mortality associated with candida infection in the NICU, prophylaxis and early treatment based on epidemiological features is necessary.

• Journal of Convergence for Information Technology
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• v.7 no.5
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• pp.67-73
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• 2017

To investigate the perception of the correlation between systemic diseases and oral health among some university students. The questionnaires were conducted on 485 students from 3 universities in Gwangju. As a result of the study, the female was higher than the male and was the highest in the fourth grade. Subjective health status, drinking status, smoking experience, and exercise were not significantly different in recognizing the association between systemic disease and oral health. The group with experience in oral health education recognized 3.18, and the group that practiced educational contents was highly recognized as 3.21. There was a significant difference between the two groups. Multiple regression analysis showed that major factor and grade factor influenced the perception of association between systemic disease and oral health. Therefore, it is necessary for university students to recognize the importance and necessity of periodical oral examinations. It is thought that the incidence of disease should be strengthened and enforced to recognize that there is a correlation with various diseases.

• Proceedings of the Korea Multimedia Society Conference
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• 2012.05a
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• pp.378-381
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• 2012

본 논문은 실버세대의 치매예방을 위한 제스처 인식 기반 3D기능성 게임을 제안한다. 제안된 기능성 게임은 전신 제스처 인식을 이용함으로써 사용자의 두뇌 사용능력과 신체활동성을 증가시켜 치매예방 효과를 향상시킬 수 있도록 구성하였다. 기존에 개발된 제스처 인식 기술에 사용된 카메라들은 인식률과 가동영역이 한계적이다. 보다 안정적인 전신 제스처 인식을 위해 3D depth 카메라로부터 사용자를 인식하고 사용자의 관절 정보를 획득하였으며 관절의 움직임을 분석하여 전신 제스처를 인식하였다. 게임 콘텐츠로는 치매의 대표적인 원인인 뇌세포의 퇴화에 초점을 맞춰 기억력, 논리력, 산술능력, 공간인지능력 등을 훈련할 수 있도록 구성하였다.

• The Journal of the Korea Contents Association
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• v.18 no.8
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• pp.607-615
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• 2018

The purpose of this study was to assess the level of awareness regarding the relationship between systemic diseases and oral health and the importance of education related to this association among dental patients, as well as to identify factors that affect the awareness of the relationship and the perceived need for education. This study was conducted from June 2016 to February 2017. Subjects of this study included outpatients (20-60 years old) from a dental clinic, and only patients who agreed to the survey were included. A total of 110 subjects were included, but the final analysis was based on 92 questionnaires, excluding questionnaires that were inaccurate. Survey questionnaires were completed by self-report and face-to-face interviews with a dental hygienist. The questionnaires covered basic information, awareness of the association between general and oral health, and experience with, and need for education related to, this association. Among the subjects, 48.9% were aware of the association between systemic diseases and oral health. A total of 39.1% of subjects had received education regarding the relationship between systemic diseases and oral health. Subjects who visited dental clinics regularly were 3.94 times (95% confidence intervals [CI]: 1.21-12.84) more likely to be aware of the association between oral health and disease compared with subjects who made only irregular visits to dental clinics. In addition, experience or education was significantly associated with awareness of the relationship between oral health and disease (odds ratio [OR]: 4.64, 95% CI: 1.54-13.93) and the need for education (OR: 3.98, 95% CI: 1.20-13.12). Thus, the dental professionals should provide education on the relationship between oral health and systemic disease in dental clinics to improve patients' awareness and oral health behaviors. These results can be used to strengthen education in the dental clinic.

• The Journal of Korea CHUNA Manual Medicine
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• v.5 no.1
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• pp.141-150
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• 2004

Objectives : The objective of this study is to evaluate the treatment effect of Oriental therapy including exercise therapy in chronic ankylosing spondylitis with total hip replacement. Methods : Oriental therapy and exercise therapy were performed for 64days admission in a patient who had chronic ankylosing spondylitis with total hip replacement and physical tests were examined. Result : Pain and ROM of cervical. lumbar spine, and left hip joint has improved with this treatment. And Anorexia, dyspepsia, and fatigue were also decreased. Conclusions: In this case, oriental therapy was proved to be effective in improving chronic symptoms and general prostration of Ankylosing Spondylitis. And It is necessary to carry out exercise therapy regulary.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.8 no.2
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• pp.109-112
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• 2012

Epidermolysis bullosa (EB) is an inherited skin disease characterized by blister formation of the skin following just minor trauma or spontaneously. The main classification of EB is based on the localization of the blistering. In epidermolysis bullosa simplex, the blister formation is intraepidermal; in epidermolysis bullosa junctionalis the blister formation in the epidermal-dermal junction; in the dystrophic forms of EB blister formation is intradermal. Oral manifestations of recessive dystrophic EB are characterized by rampant caries, crowding, microstomia, ankyloglossia, vestibular obliteration. Dental therapy may be well provided to patient with recessive dystrophic EB by using general anesthesia especially in case of poor cooperation. A two years old girl with recessive dystrophic EB visited our clinic for rampant caries. She was hospitalized for severe anemia and fever, and we provided dental therapy under general anesthesia. Extraction of incisors and stainless steel crown restoration of primary molars were performed.

• Journal of Veterinary Clinics
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• v.18 no.4
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• pp.429-433
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• 2001

Lymphoma is one of the most common malignant neoplasms of the dog. Little has been published on intraocular lymphoma in dogs. This report presents a 8-year-old neutered male mixed dog with a previous history on inflammatory debris on the anterior and posterior lens capsules, vitreal hemorrhage, generalized peri-pheral lymphadenopathy and a palpable mid-abodominal mass. History, clinical signs, radiography, cytology, histopathology and chemotherapeutic response confirmed multicentric lymphoma with secondary ocular infla-mmation. Intraocular lymphoma, the most common secondary neoplasm of the canine eye, may be the present-ing evidence of systemic disease. This report describes a dog that presented with ocular manifestations of multicentric lymphoma.